AR115975A1 - Animales transgénicos y embriones transgénicos productores de una nucleasa de diseño mediante ingeniería - Google Patents

Animales transgénicos y embriones transgénicos productores de una nucleasa de diseño mediante ingeniería

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Publication number
AR115975A1
AR115975A1 ARP190102344A ARP190102344A AR115975A1 AR 115975 A1 AR115975 A1 AR 115975A1 AR P190102344 A ARP190102344 A AR P190102344A AR P190102344 A ARP190102344 A AR P190102344A AR 115975 A1 AR115975 A1 AR 115975A1
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Argentina
Prior art keywords
transgenic
toolkit
locus
genome
cell
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ARP190102344A
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English (en)
Inventor
Ji Hyun Park
Gyeong Min Gim
Soo Young Yum
Won You Lee
Goo Jang
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Lart Bio Co Ltd
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Publication date
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Publication of AR115975A1 publication Critical patent/AR115975A1/es

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  • Life Sciences & Earth Sciences (AREA)
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Abstract

La presente descripción se relaciona con un animal transgénico y un embrión transgénico que producen componentes de una nucleasa de diseño mediante ingeniería. De acuerdo con la divulgación de la presente descripción, el animal transgénico (o embrión) que produce los componentes de una nucleasa de diseño mediante ingeniería es un animal (o embrión) transgénico que incluye una primera célula que tiene un genoma que incluye una primera caja de herramientas; y una segunda célula que tiene un genoma que incluye una segunda caja de herramientas, en donde la primera caja de herramientas y la segunda caja de herramientas incluyen al menos uno de un polinucleótido que codifica una endonucleasa guiada por ARN y un polinucleótido que codifica un ácido nucleico guía que es capaz de unirse específicamente a un sitio diana, respectivamente, en donde la primera caja de herramientas está presente en un primer locus del genoma de la primera célula; la segunda caja de herramientas está presente en un segundo locus del genoma de la segunda célula; y el primer locus es diferente del segundo locus.
ARP190102344A 2018-08-16 2019-08-16 Animales transgénicos y embriones transgénicos productores de una nucleasa de diseño mediante ingeniería AR115975A1 (es)

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US (1) US12029204B2 (es)
JP (4) JP7060256B2 (es)
KR (8) KR102158428B1 (es)
AR (1) AR115975A1 (es)
AU (3) AU2019275586B2 (es)
BR (1) BR112020000388A2 (es)

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KR102158428B1 (ko) 2018-08-16 2020-09-22 (주)라트바이오 인위적 뉴클레아제를 생산하는 형질전환 배아 및 형질전환 동물의 제작 방법
JP2023176590A (ja) * 2022-05-31 2023-12-13 株式会社ポル・メド・テック 遺伝子導入ブタの製造方法、体細胞クローニング原料、遺伝子導入ブタ、樹立された体細胞、及び組織ないし臓器
WO2024020111A1 (en) * 2022-07-20 2024-01-25 Syntax Bio, Inc. Systems for cell programming and methods thereof
CN117737136A (zh) * 2023-01-20 2024-03-22 中国科学院水生生物研究所 优化的雌鱼育性控制的方法及应用
CN117737122A (zh) * 2023-01-20 2024-03-22 中国科学院水生生物研究所 雌鱼育性控制的方法及应用

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KR102158428B1 (ko) 2018-08-16 2020-09-22 (주)라트바이오 인위적 뉴클레아제를 생산하는 형질전환 배아 및 형질전환 동물의 제작 방법

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US20210337776A1 (en) 2021-11-04
KR20210004925A (ko) 2021-01-13
KR102103104B1 (ko) 2020-04-22
JP2020534789A (ja) 2020-12-03
KR20200045452A (ko) 2020-05-04
KR102158428B1 (ko) 2020-09-22
JP7060256B2 (ja) 2022-04-26
KR102471750B1 (ko) 2022-11-28
AU2019275586B2 (en) 2021-06-17
KR102197703B1 (ko) 2020-12-31
KR20200020580A (ko) 2020-02-26
KR20200045453A (ko) 2020-05-04
KR20200021042A (ko) 2020-02-27
KR102103103B1 (ko) 2020-04-21
BR112020000388A2 (pt) 2021-03-09
JP2022095839A (ja) 2022-06-28
JP2022095840A (ja) 2022-06-28
AU2021232801B2 (en) 2024-05-02
JP2024045299A (ja) 2024-04-02
JP7430413B2 (ja) 2024-02-13
KR102608838B1 (ko) 2023-12-01
KR102471751B1 (ko) 2022-11-28
AU2021232802A1 (en) 2021-10-14
KR20210003070A (ko) 2021-01-11
AU2021232801A1 (en) 2021-10-14
JP7430414B2 (ja) 2024-02-13
KR20220163905A (ko) 2022-12-12
US12029204B2 (en) 2024-07-09
KR102197707B1 (ko) 2020-12-31
KR20200020579A (ko) 2020-02-26
AU2019275586A1 (en) 2020-03-05

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