AR104554A1 - Sistema de control del proceso de regulación y control de una planta de estructura modular para la obtención de productos biofarmacéuticos y biológicos macromoleculares - Google Patents

Sistema de control del proceso de regulación y control de una planta de estructura modular para la obtención de productos biofarmacéuticos y biológicos macromoleculares

Info

Publication number
AR104554A1
AR104554A1 ARP160101310A ARP160101310A AR104554A1 AR 104554 A1 AR104554 A1 AR 104554A1 AR P160101310 A ARP160101310 A AR P160101310A AR P160101310 A ARP160101310 A AR P160101310A AR 104554 A1 AR104554 A1 AR 104554A1
Authority
AR
Argentina
Prior art keywords
biopharmaceutical
modular structure
biological products
regulation
control system
Prior art date
Application number
ARP160101310A
Other languages
English (en)
Spanish (es)
Inventor
Dr Bernshausen Jens
Dr Lobedann Martin
Dr Schwan Peter
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53177195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR104554(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of AR104554A1 publication Critical patent/AR104554A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/44Multiple separable units; Modules
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/58Reaction vessels connected in series or in parallel
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10Perfusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05DSYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D7/00Control of flow
    • G05D7/06Control of flow characterised by the use of electric means
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05BCONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B11/00Automatic controllers
    • G05B11/01Automatic controllers electric
    • G05B11/36Automatic controllers electric with provision for obtaining particular characteristics, e.g. proportional, integral, differential
    • G05B11/42Automatic controllers electric with provision for obtaining particular characteristics, e.g. proportional, integral, differential for obtaining a characteristic which is both proportional and time-dependent, e.g. P. I., P. I. D.
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05BCONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B13/00Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion
    • G05B13/02Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
    • G05B13/0265Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric the criterion being a learning criterion
    • G05B13/0275Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric the criterion being a learning criterion using fuzzy logic only

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Computer Hardware Design (AREA)
  • General Physics & Mathematics (AREA)
  • Automation & Control Theory (AREA)
  • Artificial Intelligence (AREA)
  • Software Systems (AREA)
  • Mathematical Physics (AREA)
  • Fuzzy Systems (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Evolutionary Computation (AREA)
  • Medical Informatics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Feedback Control In General (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Testing And Monitoring For Control Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Flow Control (AREA)
ARP160101310A 2015-05-13 2016-05-06 Sistema de control del proceso de regulación y control de una planta de estructura modular para la obtención de productos biofarmacéuticos y biológicos macromoleculares AR104554A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15167538.6A EP3093335A1 (de) 2015-05-13 2015-05-13 Prozessleitsystem zur regelung und steuerung einer modular aufgebauten anlage zur produktion von biopharmazeutischen und biologischen makromolekularen produkten

Publications (1)

Publication Number Publication Date
AR104554A1 true AR104554A1 (es) 2017-07-26

Family

ID=53177195

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP160101310A AR104554A1 (es) 2015-05-13 2016-05-06 Sistema de control del proceso de regulación y control de una planta de estructura modular para la obtención de productos biofarmacéuticos y biológicos macromoleculares

Country Status (21)

Country Link
US (2) US20180127461A1 (https=)
EP (2) EP3093335A1 (https=)
JP (1) JP6833721B2 (https=)
KR (1) KR20180005225A (https=)
CN (1) CN107849506B (https=)
AR (1) AR104554A1 (https=)
AU (1) AU2016259746B2 (https=)
BR (1) BR112017024373B1 (https=)
CA (1) CA2985678A1 (https=)
DK (1) DK3294856T3 (https=)
ES (1) ES2760468T3 (https=)
IL (1) IL255556B (https=)
MX (1) MX380681B (https=)
PL (1) PL3294856T3 (https=)
PT (1) PT3294856T (https=)
RU (1) RU2724495C2 (https=)
SA (1) SA517390330B1 (https=)
SG (1) SG11201709329YA (https=)
TW (1) TWI689303B (https=)
WO (1) WO2016180798A1 (https=)
ZA (1) ZA201708418B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3431173A1 (en) 2017-07-19 2019-01-23 Bayer Pharma Aktiengesellschaft Continuous manufacture of guidance molecule drug conjugates
CN112639850A (zh) * 2018-09-05 2021-04-09 联邦科学和工业研究组织 用于多参数制造过程的监视器
EP3699697A1 (en) 2019-02-25 2020-08-26 Bayer Aktiengesellschaft Automated simultaneous process control
JP7604486B2 (ja) * 2020-05-29 2024-12-23 株式会社ダイセル 異常変調原因特定装置、異常変調原因特定方法及び異常変調原因特定プログラム
EP4544020A1 (de) 2022-06-24 2025-04-30 Bilfinger Life Science GmbH Modulare vorrichtung und verfahren zur kontinuierlichen herstellung von biotechnologischen produkten
DE102022208467A1 (de) 2022-06-24 2024-01-04 Bilfinger Life Science Gmbh Modulare Vorrichtung und Verfahren zur kontinuierlichen Herstellung von biotechnologischen Produkten
EP4711439A1 (en) 2024-09-16 2026-03-18 Sartorius Stedim Biotech GmbH Flow system with recirculation loop

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994011838A1 (en) * 1992-11-06 1994-05-26 Abbott Laboratories Process control system for biological fluid testing
JP2004198123A (ja) * 2002-12-16 2004-07-15 Shimadzu Corp 分取液体クロマトグラフ質量分析装置
JP3823092B2 (ja) * 2003-03-11 2006-09-20 株式会社日立ハイテクノロジーズ 分離分析装置
JP2006018711A (ja) * 2004-07-05 2006-01-19 Earekkusu:Kk 液体除染剤供給システム
WO2006039588A2 (en) 2004-09-30 2006-04-13 Bayer Healthcare Llc Devices and methods for integrated continuous manufacturing of biological molecules
CN101321856A (zh) * 2005-05-09 2008-12-10 萨克松尼亚生物科技有限责任公司 用于细胞培养模块的供应系统
CN101400418B (zh) * 2006-03-17 2012-11-14 沃特世科技公司 保持流体完整性和预先形成梯度的适于液相色谱的溶剂输送系统
JP4831480B2 (ja) * 2006-06-21 2011-12-07 三浦工業株式会社 膜濾過システム
WO2012072822A1 (en) * 2010-12-03 2012-06-07 Mindseeds Laboratories Srl Microanalysis of cellular function
KR102027596B1 (ko) * 2010-12-06 2019-10-01 타폰 바이오시스템즈, 인코포레이티드 생물학적 산물을 위한 연속 처리 방법
CN103243026B (zh) * 2012-02-14 2014-09-03 常州医凌生命科技有限公司 多功能全自动细胞及溶液处理仪
EP2682168A1 (en) * 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
WO2014112527A1 (ja) * 2013-01-18 2014-07-24 株式会社島津製作所 サンプル濃縮装置
SG10201709131UA (en) 2013-03-08 2017-12-28 Genzyme Corp Continuous purification of therapeutic proteins
DE102013212540A1 (de) * 2013-06-27 2014-12-31 Agilent Technologies Inc. Konditionieren eines nachfolgenden Probenpakets in einer Probentrennstufe während Prozessierens eines vorangehenden Probenpakets in einer Probenweiterverarbeitungsstufe
CN107406816B (zh) * 2014-07-31 2021-10-12 马里兰大学巴尔的摩分校 用于从人类血液制造蛋白质的微量生物处理系统和方法

Also Published As

Publication number Publication date
SA517390330B1 (ar) 2021-09-22
EP3294856A1 (de) 2018-03-21
JP2018524668A (ja) 2018-08-30
SG11201709329YA (en) 2017-12-28
IL255556A (en) 2018-01-31
RU2017143437A (ru) 2019-06-13
ZA201708418B (en) 2022-08-31
TWI689303B (zh) 2020-04-01
MX2017014527A (es) 2018-03-12
AU2016259746A1 (en) 2017-12-07
CA2985678A1 (en) 2016-11-17
MX380681B (es) 2025-03-12
US20180127461A1 (en) 2018-05-10
BR112017024373A2 (pt) 2018-07-31
PL3294856T3 (pl) 2020-04-30
HK1252939A1 (zh) 2019-06-06
US20210221842A1 (en) 2021-07-22
KR20180005225A (ko) 2018-01-15
RU2724495C2 (ru) 2020-06-23
EP3294856B1 (de) 2019-09-18
RU2017143437A3 (https=) 2019-08-29
EP3093335A1 (de) 2016-11-16
WO2016180798A1 (de) 2016-11-17
CN107849506A (zh) 2018-03-27
BR112017024373B1 (pt) 2022-08-09
JP6833721B2 (ja) 2021-02-24
AU2016259746A8 (en) 2018-04-05
TW201717886A (zh) 2017-06-01
DK3294856T3 (da) 2019-12-09
AU2016259746B2 (en) 2020-12-24
ES2760468T3 (es) 2020-05-14
IL255556B (en) 2022-04-01
PT3294856T (pt) 2019-12-16
CN107849506B (zh) 2020-11-03

Similar Documents

Publication Publication Date Title
AR104554A1 (es) Sistema de control del proceso de regulación y control de una planta de estructura modular para la obtención de productos biofarmacéuticos y biológicos macromoleculares
MX2017003847A (es) Proteinas biespecificas activables por proteasas.
MX2021000209A (es) Metodos y productos para transfeccion de celulas.
HK1252166A1 (zh) 从环状rna产生环状dna的方法
BR112017008518A2 (pt) indutores de haploidia
MX2020006065A (es) Metodos y productos para la produccion y administracion de acido nucleico.
EA201700497A1 (ru) Способ культивирования бактерий
MX390738B (es) Metodo para producir plantas de genoma modificado a partir de protoplastos de planta a alta eficiencia.
MX393723B (es) Elementos de regulación de plantas y sus usos.
EP3293265A4 (en) Production method for exosome comprising target protein, and method for transferring target protein into cytoplasm by using exosome produced by means of the production method
AR099462A1 (es) Unidad de ultrafiltración para el intercambio continuo de medio o tampón de una solución proteica
AR103226A1 (es) Inductor de haploides
SG11201802922QA (en) Promoter system inducing expression by 3-hydroxypropionic acid and method for biological production of 3-hydroxypropionic acid using same
AR095662A1 (es) Elementos reguladores de plantas y sus usos
MY197735A (en) Pharmaceutical combinations comprising an anti-ly75 antibody
CR20150554A (es) Elementos regulatorios de planta y sus usos
EP3387108A4 (en) METHOD FOR THE DISPOSAL OF NUCLEIC ACIDS BY NANOPORES
MX351264B (es) Proteína quitinasa insecticida novedosa, su nucleótido codificador y su aplicación.
MX378585B (es) Sistema de expresion bacterial bicistronico
PY1577192A (es) Supresión de arni parental de gen de hunchback para el control de las plagas de hemípteros
CO2017009163A2 (es) Moléculas de ácido nucleico de arn polimerasa ii33 para el control de plagas de insectos
UY40808A (es) Molécula de adn recombinante aislada con actividad reguladora de genes y método para producir una planta transgénica
BR112017012389A2 (pt) supressão de rnai parental de gene kruppel para controlar pragas de coleóptero
CO2017009158A2 (es) Moléculas de ácido nucleico de arn polimerasa ii215 para el control de plagas de insectos
AR106857A1 (es) Elementos reguladores de plantas y métodos para usarlos

Legal Events

Date Code Title Description
FA Abandonment or withdrawal