AR103852A1 - DsbA Y DsbC ULTRAPURIFICADOS Y SUS MÉTODOS DE PREPARACIÓN Y USO - Google Patents
DsbA Y DsbC ULTRAPURIFICADOS Y SUS MÉTODOS DE PREPARACIÓN Y USOInfo
- Publication number
- AR103852A1 AR103852A1 ARP160100573A ARP160100573A AR103852A1 AR 103852 A1 AR103852 A1 AR 103852A1 AR P160100573 A ARP160100573 A AR P160100573A AR P160100573 A ARP160100573 A AR P160100573A AR 103852 A1 AR103852 A1 AR 103852A1
- Authority
- AR
- Argentina
- Prior art keywords
- dsbc
- dsba
- ultrapurified
- preparation
- use methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 101000874039 Bacillus phage SPbeta Disulfide bond formation protein A Proteins 0.000 abstract 1
- 101000874036 Bacillus subtilis (strain 168) SPbeta prophage-derived disulfide bond formation protein A Proteins 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 101710147276 Probable disulfide formation protein C Proteins 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0051—Oxidoreductases (1.) acting on a sulfur group of donors (1.8)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y108/00—Oxidoreductases acting on sulfur groups as donors (1.8)
- C12Y108/04—Oxidoreductases acting on sulfur groups as donors (1.8) with a disulfide as acceptor (1.8.4)
- C12Y108/04002—Protein-disulfide reductase (glutathione) (1.8.4.2), i.e. BdbC or BdbD
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y503/00—Intramolecular oxidoreductases (5.3)
- C12Y503/04—Intramolecular oxidoreductases (5.3) transposing S-S bonds (5.3.4)
- C12Y503/04001—Protein disulfide-isomerase (5.3.4.1), i.e. disufide bond-forming enzyme
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/90212—Oxidoreductases (1.) acting on a sulfur group of donors (1.8)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/99—Isomerases (5.)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562129701P | 2015-03-06 | 2015-03-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR103852A1 true AR103852A1 (es) | 2017-06-07 |
Family
ID=55637452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP160100573A AR103852A1 (es) | 2015-03-06 | 2016-03-04 | DsbA Y DsbC ULTRAPURIFICADOS Y SUS MÉTODOS DE PREPARACIÓN Y USO |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US10073098B2 (OSRAM) |
| EP (2) | EP3265557B1 (OSRAM) |
| JP (2) | JP6865689B2 (OSRAM) |
| KR (1) | KR20170122216A (OSRAM) |
| CN (1) | CN107531749A (OSRAM) |
| AR (1) | AR103852A1 (OSRAM) |
| AU (1) | AU2016230018A1 (OSRAM) |
| CA (1) | CA2978256A1 (OSRAM) |
| ES (1) | ES2761726T3 (OSRAM) |
| HK (1) | HK1247936A1 (OSRAM) |
| HR (1) | HRP20192217T1 (OSRAM) |
| IL (1) | IL254166A0 (OSRAM) |
| MX (2) | MX387454B (OSRAM) |
| PL (1) | PL3265557T3 (OSRAM) |
| SG (2) | SG11201707186YA (OSRAM) |
| SI (1) | SI3265557T1 (OSRAM) |
| WO (1) | WO2016144824A1 (OSRAM) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| WO2015105955A1 (en) | 2014-01-08 | 2015-07-16 | Flodesign Sonics, Inc. | Acoustophoresis device with dual acoustophoretic chamber |
| ES2761726T3 (es) | 2015-03-06 | 2020-05-20 | Hoffmann La Roche | DsbA y DsbC ultrapurificadas y procedimientos de preparación y uso de las mismas |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| BR112020009889A2 (pt) | 2017-12-14 | 2020-11-03 | Flodesign Sonics, Inc. | acionador e controlador de transdutor acústico |
| TWI870412B (zh) * | 2019-06-05 | 2025-01-21 | 美商建南德克公司 | 過載層析管柱之再生方法 |
| WO2021207657A1 (en) * | 2020-04-09 | 2021-10-14 | Cytomx Therapeutics, Inc. | Compositions containing activatable antibodies |
| CN115028691B (zh) * | 2022-06-29 | 2024-09-10 | 青岛硕景生物科技有限公司 | 一种检测试纸用的独立质控系统、杂交瘤细胞株、质控线用包被单克隆抗体及其应用 |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2031216A1 (de) | 1969-06-19 | 1971-01-14 | Citizen Watch Co Ltd , Tokio | Tag und Datum Stellvorrichtung fur Uhren mit Kalender |
| US3691016A (en) | 1970-04-17 | 1972-09-12 | Monsanto Co | Process for the preparation of insoluble enzymes |
| US3940475A (en) | 1970-06-11 | 1976-02-24 | Biological Developments, Inc. | Radioimmune method of assaying quantitatively for a hapten |
| CA1023287A (en) | 1972-12-08 | 1977-12-27 | Boehringer Mannheim G.M.B.H. | Process for the preparation of carrier-bound proteins |
| US4195128A (en) | 1976-05-03 | 1980-03-25 | Bayer Aktiengesellschaft | Polymeric carrier bound ligands |
| US4330440A (en) | 1977-02-08 | 1982-05-18 | Development Finance Corporation Of New Zealand | Activated matrix and method of activation |
| CA1093991A (en) | 1977-02-17 | 1981-01-20 | Hideo Hirohara | Enzyme immobilization with pullulan gel |
| US4229537A (en) | 1978-02-09 | 1980-10-21 | New York University | Preparation of trichloro-s-triazine activated supports for coupling ligands |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US5508192A (en) | 1990-11-09 | 1996-04-16 | Board Of Regents, The University Of Texas System | Bacterial host strains for producing proteolytically sensitive polypeptides |
| US5264365A (en) | 1990-11-09 | 1993-11-23 | Board Of Regents, The University Of Texas System | Protease-deficient bacterial strains for production of proteolytically sensitive polypeptides |
| US5571894A (en) | 1991-02-05 | 1996-11-05 | Ciba-Geigy Corporation | Recombinant antibodies specific for a growth factor receptor |
| DE122004000008I1 (de) | 1991-06-14 | 2005-06-09 | Genentech Inc | Humanisierter Heregulin Antikörper. |
| IE922437A1 (en) | 1991-07-25 | 1993-01-27 | Idec Pharma Corp | Recombinant antibodies for human therapy |
| WO1993006217A1 (en) | 1991-09-19 | 1993-04-01 | Genentech, Inc. | EXPRESSION IN E. COLI OF ANTIBODY FRAGMENTS HAVING AT LEAST A CYSTEINE PRESENT AS A FREE THIOL, USE FOR THE PRODUCTION OF BIFUNCTIONAL F(ab')2 ANTIBODIES |
| FI941572A7 (fi) | 1991-10-07 | 1994-05-27 | Oncologix Inc | Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenete lmä |
| WO1993008829A1 (en) | 1991-11-04 | 1993-05-13 | The Regents Of The University Of California | Compositions that mediate killing of hiv-infected cells |
| EP1136556B1 (en) | 1991-11-25 | 2005-06-08 | Enzon, Inc. | Method of producing multivalent antigen-binding proteins |
| JPH08500962A (ja) | 1992-02-06 | 1996-02-06 | クリエイティブ バイオモレキュルズ，インコーポレイテッド | 癌マーカー用生物合成結合蛋白質 |
| ATE149570T1 (de) | 1992-08-17 | 1997-03-15 | Genentech Inc | Bispezifische immunoadhesine |
| GB9325718D0 (en) * | 1993-12-16 | 1994-02-16 | Ars Holding 89 Nv | Sensor device for sandwich assay |
| US5639635A (en) | 1994-11-03 | 1997-06-17 | Genentech, Inc. | Process for bacterial production of polypeptides |
| US5789199A (en) | 1994-11-03 | 1998-08-04 | Genentech, Inc. | Process for bacterial production of polypeptides |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| US5641870A (en) | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
| US6027888A (en) | 1996-04-05 | 2000-02-22 | Board Of Regents, The University Of Texas System | Methods for producing soluble, biologically-active disulfide-bond containing eukaryotic proteins in bacterial cells |
| US6083715A (en) | 1997-06-09 | 2000-07-04 | Board Of Regents, The University Of Texas System | Methods for producing heterologous disulfide bond-containing polypeptides in bacterial cells |
| JP2000083670A (ja) | 1998-09-09 | 2000-03-28 | Hsp Kenkyusho:Kk | ＤｓｂＡ／ＤｓｂＢ／ＤｓｂＣ／ＤｓｂＤ発現プラスミド |
| IL127127A0 (en) | 1998-11-18 | 1999-09-22 | Peptor Ltd | Small functional units of antibody heavy chain variable regions |
| CA2364568A1 (en) * | 1999-03-17 | 2000-09-21 | Adrian Woolfson | Method for refolding molecules of polypeptides containing ig domains |
| US6872563B1 (en) * | 1999-10-05 | 2005-03-29 | President And Fellows Of Harvard College | Compositions and methods for production of disulfide bond containing proteins in host cells |
| SI2857516T1 (sl) | 2000-04-11 | 2017-09-29 | Genentech, Inc. | Multivalentna protitelesa in njihove uporabe |
| CA2430182C (en) | 2000-12-14 | 2011-01-25 | Genentech, Inc. | Prokaryotically produced antibodies and uses thereof |
| US8372954B2 (en) | 2000-12-22 | 2013-02-12 | National Research Council Of Canada | Phage display libraries of human VH fragments |
| JP2005289809A (ja) | 2001-10-24 | 2005-10-20 | Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) | 突然変異重鎖抗体 |
| DK1639011T3 (da) | 2003-06-30 | 2009-02-16 | Domantis Ltd | Pegylerede enkelt-domæne antistoffer (dAb) |
| ATE554107T1 (de) | 2003-12-19 | 2012-05-15 | Genentech Inc | Als therapeutika geeignete monovalente antikörperfragmente |
| TR201808537T4 (tr) | 2004-09-23 | 2018-07-23 | Genentech Inc | Sistein değiştirilmiş antikorlar ve konjugatlar. |
| CN100475965C (zh) | 2005-07-22 | 2009-04-08 | 上海高科联合生物技术研发有限公司 | 一种大肠杆菌高效外分泌表达溶葡萄球菌酶的方法 |
| EP2035456A1 (en) | 2006-06-22 | 2009-03-18 | Novo Nordisk A/S | Production of bispecific antibodies |
| ES2399075T3 (es) | 2006-08-30 | 2013-03-25 | Genentech, Inc. | Anticuerpos multiespecíficos |
| AU2008209404B2 (en) * | 2007-01-22 | 2012-08-16 | Genentech, Inc. | Polyelectrolyte precipitation and purification of antibodies |
| WO2009089004A1 (en) | 2008-01-07 | 2009-07-16 | Amgen Inc. | Method for making antibody fc-heterodimeric molecules using electrostatic steering effects |
| KR101968766B1 (ko) * | 2009-11-05 | 2019-04-12 | 제넨테크, 인크. | 이종 폴리펩티드의 분비를 위한 방법 및 조성물 |
| AU2010201410B2 (en) * | 2010-03-30 | 2015-04-30 | Pelican Technology Holdings, Inc. | High level expression of recombinant CRM197 |
| GB201012519D0 (en) | 2010-07-26 | 2010-09-08 | Ucl Business Plc | Method and system for anomaly detection in data sets |
| GB201012599D0 (en) * | 2010-07-27 | 2010-09-08 | Ucb Pharma Sa | Process for purifying proteins |
| SI2773438T2 (sl) * | 2011-11-02 | 2022-05-31 | F.Hoffmann-La Roche Ag | Izpiralna kromatografija s preobremenitvijo |
| JP6463732B2 (ja) * | 2013-04-19 | 2019-02-06 | ストロ バイオファーマ， インコーポレイテッド | 上昇したレベルの外因性シャペロンを有する細胞抽出物を用いる細菌無細胞合成系における生物活性のあるタンパク質の発現 |
| CA3174012A1 (en) * | 2013-09-13 | 2015-03-19 | Genentech, Inc. | Compositions and methods for detecting and quantifying host cell protein in cell lines and recombinant polypeptide products |
| ES2761726T3 (es) | 2015-03-06 | 2020-05-20 | Hoffmann La Roche | DsbA y DsbC ultrapurificadas y procedimientos de preparación y uso de las mismas |
-
2016
- 2016-03-04 ES ES16712126T patent/ES2761726T3/es active Active
- 2016-03-04 EP EP16712126.8A patent/EP3265557B1/en active Active
- 2016-03-04 CN CN201680026013.3A patent/CN107531749A/zh active Pending
- 2016-03-04 HK HK18107289.5A patent/HK1247936A1/zh unknown
- 2016-03-04 CA CA2978256A patent/CA2978256A1/en not_active Abandoned
- 2016-03-04 HR HRP20192217TT patent/HRP20192217T1/hr unknown
- 2016-03-04 MX MX2021000153A patent/MX387454B/es unknown
- 2016-03-04 WO PCT/US2016/021059 patent/WO2016144824A1/en not_active Ceased
- 2016-03-04 US US15/061,943 patent/US10073098B2/en active Active
- 2016-03-04 SG SG11201707186YA patent/SG11201707186YA/en unknown
- 2016-03-04 KR KR1020177026459A patent/KR20170122216A/ko not_active Ceased
- 2016-03-04 EP EP19195777.8A patent/EP3636749B1/en active Active
- 2016-03-04 PL PL16712126T patent/PL3265557T3/pl unknown
- 2016-03-04 AU AU2016230018A patent/AU2016230018A1/en not_active Abandoned
- 2016-03-04 JP JP2017546779A patent/JP6865689B2/ja active Active
- 2016-03-04 MX MX2017011189A patent/MX381844B/es unknown
- 2016-03-04 AR ARP160100573A patent/AR103852A1/es not_active Application Discontinuation
- 2016-03-04 SG SG10202005917SA patent/SG10202005917SA/en unknown
- 2016-03-04 SI SI201630544T patent/SI3265557T1/sl unknown
-
2017
- 2017-08-27 IL IL254166A patent/IL254166A0/en unknown
-
2018
- 2018-07-24 US US16/044,360 patent/US10690671B2/en active Active
-
2021
- 2021-01-07 JP JP2021001186A patent/JP7191132B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| MX2021000153A (es) | 2021-10-28 |
| CA2978256A1 (en) | 2016-09-15 |
| US20160370369A1 (en) | 2016-12-22 |
| MX387454B (es) | 2025-03-18 |
| KR20170122216A (ko) | 2017-11-03 |
| SI3265557T1 (sl) | 2020-02-28 |
| JP2018516229A (ja) | 2018-06-21 |
| IL254166A0 (en) | 2017-10-31 |
| US10073098B2 (en) | 2018-09-11 |
| ES2761726T3 (es) | 2020-05-20 |
| MX2017011189A (es) | 2018-01-23 |
| EP3265557A1 (en) | 2018-01-10 |
| CN107531749A (zh) | 2018-01-02 |
| PL3265557T3 (pl) | 2020-03-31 |
| HK1247936A1 (zh) | 2018-10-05 |
| JP7191132B2 (ja) | 2022-12-16 |
| SG10202005917SA (en) | 2020-07-29 |
| JP6865689B2 (ja) | 2021-04-28 |
| EP3636749B1 (en) | 2022-04-27 |
| US20190056399A1 (en) | 2019-02-21 |
| EP3636749A1 (en) | 2020-04-15 |
| JP2021078502A (ja) | 2021-05-27 |
| US10690671B2 (en) | 2020-06-23 |
| AU2016230018A1 (en) | 2017-09-21 |
| MX381844B (es) | 2025-03-13 |
| HRP20192217T1 (hr) | 2020-02-21 |
| EP3265557B1 (en) | 2019-10-16 |
| SG11201707186YA (en) | 2017-10-30 |
| WO2016144824A1 (en) | 2016-09-15 |
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