MX2019010890A - Compuestos antineoplasicos. - Google Patents

Compuestos antineoplasicos.

Info

Publication number
MX2019010890A
MX2019010890A MX2019010890A MX2019010890A MX2019010890A MX 2019010890 A MX2019010890 A MX 2019010890A MX 2019010890 A MX2019010890 A MX 2019010890A MX 2019010890 A MX2019010890 A MX 2019010890A MX 2019010890 A MX2019010890 A MX 2019010890A
Authority
MX
Mexico
Prior art keywords
compounds
phm005
anticancer compounds
strain
anticancer
Prior art date
Application number
MX2019010890A
Other languages
English (en)
Inventor
María Cañedo Hernández Librada
De La Calle Verdú Fernando
Pilar Rodríguez Ramos María
Del Carmen Schleissner Sánchez María
Zúñiga Girón Paz
Original Assignee
Pharma Mar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharma Mar Sa filed Critical Pharma Mar Sa
Publication of MX2019010890A publication Critical patent/MX2019010890A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/38—Pseudomonas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Compuestos antineoplásicos de fórmula general I (ver formula) en la que R1 a R4 toman diversos significados, para su uso en el tratamiento de cáncer. Se proporcionan también una cepa novedosa de Labrenzia sp. denominada PHM005 con número de depósito de registro CECT-9225, un método para producir compuestos de la invención y análogos de los mismos usando la cepa PHM005 y la agrupación génica de laboratorio que codifica para la 10 biosíntesis de compuestos similares a pederina y similares a onnamida.
MX2019010890A 2017-03-17 2018-03-16 Compuestos antineoplasicos. MX2019010890A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17382140 2017-03-17
PCT/EP2018/056665 WO2018167270A1 (en) 2017-03-17 2018-03-16 Anticancer compounds

Publications (1)

Publication Number Publication Date
MX2019010890A true MX2019010890A (es) 2019-12-19

Family

ID=58398130

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2019010890A MX2019010890A (es) 2017-03-17 2018-03-16 Compuestos antineoplasicos.
MX2021011385A MX2021011385A (es) 2017-03-17 2019-09-12 Compuestos antineoplasicos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021011385A MX2021011385A (es) 2017-03-17 2019-09-12 Compuestos antineoplasicos.

Country Status (17)

Country Link
US (1) US20210317490A1 (es)
EP (1) EP3596068A1 (es)
JP (1) JP7209633B2 (es)
KR (1) KR102547649B1 (es)
CN (1) CN110650954B (es)
AU (2) AU2018235140B2 (es)
BR (1) BR112019019301A2 (es)
CA (1) CA3056725A1 (es)
CL (2) CL2019002661A1 (es)
IL (2) IL292572A (es)
MA (1) MA49880A (es)
MX (2) MX2019010890A (es)
MY (1) MY195435A (es)
SG (1) SG11201908267XA (es)
UA (1) UA126338C2 (es)
WO (1) WO2018167270A1 (es)
ZA (2) ZA201906518B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021043951A1 (en) 2019-09-05 2021-03-11 Pharma Mar, S.A. Drug antibody conjugates
CN112661808B (zh) * 2020-12-23 2022-05-27 浙江大学 一种酯肽类化合物及其制备方法和应用
EP4326869A1 (en) * 2021-04-20 2024-02-28 University of Louisville Recombinant miropin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3867526D1 (de) 1987-04-29 1992-02-20 Harbor Branch Oceanographic Antitumor- und antivirale verbindungen marinen ursprungs.
US4801606A (en) 1987-07-17 1989-01-31 Harbor Branch Oceanographic Institution Inc. Antiviral compositions
JP2005509435A (ja) 2001-11-22 2005-04-14 マックス−プランク ゲゼルシャフト ツァー フォルデルング デア ビッセンシャフテン エー．ファウ． ペデリン生合成遺伝子の新規な遺伝子クラスター
US9364555B2 (en) 2011-07-22 2016-06-14 University of Pittsburgh—of the Commonwealth System of Higher Education Pederin and psymberin agents

Also Published As

Publication number Publication date
CA3056725A1 (en) 2018-09-20
ZA201906518B (en) 2021-01-27
KR102547649B1 (ko) 2023-06-23
RU2019132808A3 (es) 2021-10-04
CL2021000117A1 (es) 2021-07-30
KR20190129950A (ko) 2019-11-20
AU2021277683B2 (en) 2023-03-09
EP3596068A1 (en) 2020-01-22
SG11201908267XA (en) 2019-10-30
CN110650954B (zh) 2023-11-03
CL2019002661A1 (es) 2019-12-27
ZA202006147B (en) 2023-03-29
AU2021277683A1 (en) 2021-12-23
IL292572A (en) 2022-06-01
MA49880A (fr) 2020-06-24
US20210317490A1 (en) 2021-10-14
IL269353A (en) 2019-11-28
UA126338C2 (uk) 2022-09-21
CN110650954A (zh) 2020-01-03
IL269353B (en) 2022-06-01
RU2019132808A (ru) 2021-04-19
JP2020510065A (ja) 2020-04-02
BR112019019301A2 (pt) 2020-04-28
WO2018167270A1 (en) 2018-09-20
MX2021011385A (es) 2021-10-13
AU2018235140B2 (en) 2021-11-11
JP7209633B2 (ja) 2023-01-20
AU2018235140A1 (en) 2019-10-03
MY195435A (en) 2023-01-20

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