AR098693A1 - Método para producir células del epitelio pigmentario retiniano (rpe) - Google Patents
Método para producir células del epitelio pigmentario retiniano (rpe)Info
- Publication number
- AR098693A1 AR098693A1 ARP140104590A ARP140104590A AR098693A1 AR 098693 A1 AR098693 A1 AR 098693A1 AR P140104590 A ARP140104590 A AR P140104590A AR P140104590 A ARP140104590 A AR P140104590A AR 098693 A1 AR098693 A1 AR 098693A1
- Authority
- AR
- Argentina
- Prior art keywords
- cells
- rpe
- retinian
- epitel
- pigmentary
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Ophthalmology & Optometry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361914445P | 2013-12-11 | 2013-12-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR098693A1 true AR098693A1 (es) | 2016-06-08 |
Family
ID=52446403
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140104590A AR098693A1 (es) | 2013-12-11 | 2014-12-10 | Método para producir células del epitelio pigmentario retiniano (rpe) |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP3080248A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2017504311A (cg-RX-API-DMAC7.html) |
| KR (1) | KR101871084B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN105814194A (cg-RX-API-DMAC7.html) |
| AR (1) | AR098693A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2014363032A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112016012129A8 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2933083A1 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1221734A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL245594A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2016007671A (cg-RX-API-DMAC7.html) |
| TW (2) | TW201823451A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015087231A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107207531B (zh) * | 2014-11-21 | 2021-05-25 | 里格尔药品股份有限公司 | 作为TGF-β抑制剂的稠合的咪唑衍生物 |
| IL273405B2 (en) * | 2014-12-30 | 2024-01-01 | Cell Cure Neurosciences Ltd | Rpe cell populations and methods of generating same |
| EP3240890B1 (en) * | 2014-12-30 | 2021-06-16 | Cell Cure Neurosciences Ltd. | Assessing retinal pigment epithelial cell populations |
| CA2972700A1 (en) * | 2014-12-30 | 2016-07-07 | Cell Cure Neurosciences Ltd. | Methods of treating retinal diseases |
| WO2017021973A1 (en) * | 2015-08-05 | 2017-02-09 | Cell Cure Neurosciences Ltd. | Preparation of retinal pigment epithelium cells |
| AU2016321170B2 (en) * | 2015-09-08 | 2022-09-01 | Fujifilm Cellular Dynamics | Method for reproducible differentiation of clinical-grade retinal pigment epithelium cells |
| CN108291206B (zh) | 2015-09-08 | 2022-07-08 | 富士胶片细胞动力公司 | 干细胞来源的视网膜色素上皮的基于macs的纯化 |
| CN108350429B (zh) | 2015-10-20 | 2022-02-25 | 富士胶片细胞动力公司 | 用于将多能干细胞定向分化为免疫细胞的方法 |
| US20180362925A1 (en) * | 2015-12-04 | 2018-12-20 | Bond University Ltd | Methods for differentiating cells |
| CN106344932B (zh) * | 2016-08-26 | 2019-12-27 | 首都医科大学附属北京同仁医院 | 一种用于提高视网膜退行性疾病基因治疗效果的组合物及其应用 |
| KR20190093199A (ko) | 2016-12-07 | 2019-08-08 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 망막 색소 상피 이식을 위해 피브린 지지체를 사용하는 방법 및 물질 |
| CN106906178A (zh) * | 2017-04-07 | 2017-06-30 | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 培养上皮细胞的组合物及其保持上皮样细胞形态中的应用 |
| KR102668891B1 (ko) | 2017-04-18 | 2024-05-29 | 후지필름 셀룰러 다이내믹스, 인코포레이티드 | 항원-특이적 면역 이펙터 세포 |
| MX2019014503A (es) * | 2017-06-05 | 2020-01-23 | Mayo Found Medical Education & Res | Metodos y materiales para cultivar, proliferar, y diferenciar celulas madre. |
| CN109957545A (zh) | 2017-12-26 | 2019-07-02 | 江苏艾尔康生物医药科技有限公司 | 一种消化rpe细胞的方法 |
| TW202012390A (zh) * | 2018-06-29 | 2020-04-01 | 日商日本歐愛特農業科技股份有限公司 | 新穎之經取代吡唑衍生物 |
| JP2022532411A (ja) * | 2019-05-15 | 2022-07-14 | ノヴォ ノルディスク アー／エス | ヒト多能性幹細胞から眼野前駆細胞を得るための方法 |
| EP4001425A4 (en) * | 2019-07-19 | 2023-04-19 | Tokyo Electron Limited | METHOD FOR ASSESSING THE STATE OF CELL DIFFERENTIATION |
| EP4008350A4 (en) | 2019-07-26 | 2023-06-14 | Saitama Medical University | ANTIBODY RECOGNIZING THE EXTRACELLULAR REGION OF ALK2/ACVR1 |
| CN113699097B (zh) * | 2021-09-08 | 2023-06-09 | 湖南光琇高新生命科技有限公司 | 视网膜色素上皮细胞的制备方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG49267A1 (en) | 1989-08-14 | 1998-05-18 | Photogenesis Inc | Surgical instrument and cell isolation and transplantation |
| US6045791A (en) | 1992-03-06 | 2000-04-04 | Photogenesis, Inc. | Retinal pigment epithelium transplantation |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US5941250A (en) | 1996-11-21 | 1999-08-24 | University Of Louisville Research Foundation Inc. | Retinal tissue implantation method |
| AU2003279132A1 (en) | 2002-10-04 | 2004-05-04 | Tissuetech, Inc. | Retinal pigment epithelial cell cultures on amniotic membrane and transplantation |
| SG10201912182UA (en) | 2004-01-23 | 2020-02-27 | Astellas Inst For Regenerative Medicine | Improved modalities for the treatment of degenerative diseases of the retina |
| CA3015835A1 (en) | 2004-11-04 | 2006-05-18 | Astellas Institute For Regenerative Medicine | Derivation of embryonic stem cells |
| US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
| US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| US20090227032A1 (en) | 2005-12-13 | 2009-09-10 | Kyoto University | Nuclear reprogramming factor and induced pluripotent stem cells |
| CN101864392B (zh) | 2005-12-13 | 2016-03-23 | 国立大学法人京都大学 | 核重新编程因子 |
| JP5441099B2 (ja) | 2007-01-18 | 2014-03-12 | 独立行政法人理化学研究所 | 視細胞への分化誘導方法 |
| CA2684242C (en) | 2007-03-23 | 2019-11-12 | Wisconsin Alumni Research Foundation | Somatic cell reprogramming |
| JP5395058B2 (ja) * | 2007-04-18 | 2014-01-22 | ハダシット メディカル リサーチ サーヴィシーズ アンド ディヴェロップメント リミテッド | 幹細胞に由来する網膜色素上皮細胞 |
| JP2008307007A (ja) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| CA3177952A1 (en) | 2007-10-12 | 2009-04-23 | Astellas Institute For Regenerative Medicine | Improved methods of producing rpe cells and compositions of rpe cells |
| GB0806746D0 (en) | 2008-04-14 | 2008-05-14 | Ucl Business Plc | Membrane |
| CA3066806C (en) | 2009-08-24 | 2023-03-07 | David M. Gamm | Substantially pure human retinal progenitor, forebrain progenitor, and retinal pigment epithelium cell cultures and methods of making the same |
| WO2011063005A2 (en) | 2009-11-17 | 2011-05-26 | Advanced Cell Technology, Inc. | Methods of producing human rpe cells and pharmaceutical preparations of human rpe cells |
| ES2542226T3 (es) | 2010-04-28 | 2015-08-03 | Technische Universität Dresden | Método para producir células progenitoras retinianas polarizadas a partir de células madre pluripotentes y su diferenciación para dar células del epitelio pigmentario retiniano |
| EP3578988B1 (en) * | 2010-05-25 | 2025-01-22 | Memorial Sloan-Kettering Cancer Center | Method of nociceptor differentiantion of human embryonic stem cells and uses thereof |
| GB201011313D0 (en) | 2010-07-05 | 2010-08-18 | Ucl Business Plc | Implantation devices, methods and implants |
| EP3549617B1 (en) | 2010-07-12 | 2023-09-13 | University of Southern California | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| US8871744B2 (en) | 2010-07-21 | 2014-10-28 | B & G Partyers, LLC | Compounds and methods for selectively targeting tumor-associated mucins |
| CN102465111A (zh) * | 2010-11-19 | 2012-05-23 | 薛志刚 | 一种体外人胚胎干细胞诱导分化为视网膜色素上皮细胞的试验方法 |
| RU2590864C2 (ru) | 2011-01-18 | 2016-07-10 | МИНИПАМПЗ, ЭлЭлСи | Хирургический инструмент для имплантации |
| WO2012177968A1 (en) | 2011-06-22 | 2012-12-27 | The Schepens Eye Research Institute, Inc. | A scaffold for subretinal cell transplantation and drug delivery |
| HUE044778T2 (hu) | 2011-11-14 | 2019-11-28 | Astellas Inst For Regenerative Medicine | Humán RPE sejt gyógyászati készítmények és alkalmazásaik |
| US9850463B2 (en) | 2012-02-01 | 2017-12-26 | The Regents Of The University Of California | Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation |
| CN102618488A (zh) * | 2012-03-15 | 2012-08-01 | 中国人民解放军第三军医大学第一附属医院 | 一种制备视网膜色素上皮细胞的方法 |
| ES2688019T3 (es) | 2012-06-05 | 2018-10-30 | The Regents Of The University Of California | Métodos y composiciones para la producción acelerada de células epiteliales pigmentadas retinianas a partir de células pluripotentes |
| AU2014212230B2 (en) | 2013-02-01 | 2019-07-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for generating retinal pigment epithelium (RPE) cells from induced pluripotent stem cells (iPSCs) |
-
2014
- 2014-12-08 WO PCT/IB2014/066703 patent/WO2015087231A1/en not_active Ceased
- 2014-12-08 KR KR1020167018138A patent/KR101871084B1/ko not_active Expired - Fee Related
- 2014-12-08 CN CN201480067617.3A patent/CN105814194A/zh active Pending
- 2014-12-08 EP EP14833537.5A patent/EP3080248A1/en not_active Withdrawn
- 2014-12-08 HK HK16109751.2A patent/HK1221734A1/zh unknown
- 2014-12-08 CA CA2933083A patent/CA2933083A1/en not_active Abandoned
- 2014-12-08 BR BR112016012129A patent/BR112016012129A8/pt not_active Application Discontinuation
- 2014-12-08 JP JP2016538000A patent/JP2017504311A/ja active Pending
- 2014-12-08 AU AU2014363032A patent/AU2014363032A1/en not_active Abandoned
- 2014-12-08 MX MX2016007671A patent/MX2016007671A/es unknown
- 2014-12-09 TW TW106131045A patent/TW201823451A/zh unknown
- 2014-12-09 TW TW103142847A patent/TW201538726A/zh unknown
- 2014-12-10 AR ARP140104590A patent/AR098693A1/es unknown
-
2016
- 2016-05-10 IL IL245594A patent/IL245594A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015087231A1 (en) | 2015-06-18 |
| JP2017504311A (ja) | 2017-02-09 |
| CA2933083A1 (en) | 2015-06-18 |
| CN105814194A (zh) | 2016-07-27 |
| BR112016012129A2 (pt) | 2017-08-08 |
| AU2014363032A1 (en) | 2016-06-09 |
| MX2016007671A (es) | 2016-10-14 |
| BR112016012129A8 (pt) | 2020-05-12 |
| IL245594A0 (en) | 2016-06-30 |
| KR20160095118A (ko) | 2016-08-10 |
| EP3080248A1 (en) | 2016-10-19 |
| KR101871084B1 (ko) | 2018-06-25 |
| TW201538726A (zh) | 2015-10-16 |
| TW201823451A (zh) | 2018-07-01 |
| HK1221734A1 (zh) | 2017-06-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |