AR094783A1 - Composiciones farmacéuticas que contienen dexketoprofeno y tramadol - Google Patents

Composiciones farmacéuticas que contienen dexketoprofeno y tramadol

Info

Publication number
AR094783A1
AR094783A1 ARP140100462A ARP140100462A AR094783A1 AR 094783 A1 AR094783 A1 AR 094783A1 AR P140100462 A ARP140100462 A AR P140100462A AR P140100462 A ARP140100462 A AR P140100462A AR 094783 A1 AR094783 A1 AR 094783A1
Authority
AR
Argentina
Prior art keywords
organic
group
tramadol
corn starch
dexketoprophene
Prior art date
Application number
ARP140100462A
Other languages
English (en)
Inventor
Schmitz Reinhard
Kohl Tobias
Original Assignee
Laboratorios Menarini S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47953547&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR094783(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Laboratorios Menarini S A filed Critical Laboratorios Menarini S A
Publication of AR094783A1 publication Critical patent/AR094783A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/133Amines having hydroxy groups, e.g. sphingosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/2853Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Una composición farmacéutica en forma de dosificación oral sólida, que comprende: i) una combinación de dos principios activos farmacológicos: sal de dexketoprofeno con una base orgánica o inorgánica y sal de tramadol con un ácido orgánico o inorgánico, donde: la base orgánica o inorgánica se selecciona entre el grupo: trometamol, trimetilamina, dimetilamina, etilamina, trietilamina, dietilamina, L-lisina, L-arginina, dietanolamina, hidróxido de sodio; el ácido orgánico o inorgánico se selecciona entre el grupo: clorhídrico, bromhídrico, fosfórico, sulfúrico, metansulfónico, bencensulfónico, toluensulfónico, acético, propiónico, málico, maleico, succínico, cítrico, L-tartárico, láctico, malónico, aspártico, glutámico; ii) celulosa microcristalina como carga; iii) un aglutinante que se selecciona entre el grupo: almidón de maíz, pregelatinizado almidón de maíz, hipromelosa o sus mezclas; iv) excipientes farmacéuticamente aceptables.
ARP140100462A 2013-02-14 2014-02-13 Composiciones farmacéuticas que contienen dexketoprofeno y tramadol AR094783A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000210A ITMI20130210A1 (it) 2013-02-14 2013-02-14 Composizioni farmaceutiche contenenti dexketoprofene e tramadolo

Publications (1)

Publication Number Publication Date
AR094783A1 true AR094783A1 (es) 2015-08-26

Family

ID=47953547

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP140100462A AR094783A1 (es) 2013-02-14 2014-02-13 Composiciones farmacéuticas que contienen dexketoprofeno y tramadol

Country Status (45)

Country Link
US (1) US9949940B2 (es)
EP (1) EP2956129B1 (es)
JP (1) JP6297068B2 (es)
KR (1) KR102262408B1 (es)
CN (1) CN105007907B (es)
AP (1) AP2015008616A0 (es)
AR (1) AR094783A1 (es)
AU (1) AU2014218110B2 (es)
BR (1) BR112015018952B1 (es)
CA (1) CA2900979C (es)
CL (1) CL2015002251A1 (es)
CR (1) CR20150411A (es)
CU (1) CU24310B1 (es)
CY (1) CY1120301T1 (es)
DK (1) DK2956129T3 (es)
EA (1) EA029709B1 (es)
EC (1) ECSP15034660A (es)
ES (1) ES2672986T3 (es)
GE (1) GEP201706649B (es)
HK (1) HK1216840A1 (es)
HR (1) HRP20180974T1 (es)
HU (1) HUE038417T2 (es)
IL (1) IL240514B (es)
IT (1) ITMI20130210A1 (es)
LT (1) LT2956129T (es)
MA (1) MA38335B1 (es)
MX (1) MX353897B (es)
MY (1) MY173102A (es)
NI (1) NI201500105A (es)
NO (1) NO2956129T3 (es)
NZ (1) NZ710967A (es)
PE (1) PE20151430A1 (es)
PH (1) PH12015501766A1 (es)
PL (1) PL2956129T3 (es)
PT (1) PT2956129T (es)
RS (1) RS57271B1 (es)
SA (1) SA515360877B1 (es)
SG (1) SG11201506291UA (es)
SI (1) SI2956129T1 (es)
TN (1) TN2015000345A1 (es)
TR (1) TR201810114T4 (es)
TW (1) TWI642430B (es)
UA (1) UA115684C2 (es)
UY (1) UY35324A (es)
WO (1) WO2014124862A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022023211A1 (en) 2020-07-31 2022-02-03 Krka, D.D., Novo Mesto Formulation containing dexketoprofen and tramadol and method for making the same

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU661723B2 (en) 1991-10-30 1995-08-03 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
US5516803A (en) * 1991-10-30 1996-05-14 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
ES2058024B1 (es) 1992-11-10 1995-05-01 Menarini Lab Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico.
DE19530575A1 (de) 1995-08-19 1997-02-20 Gruenenthal Gmbh Schnell zerfallende Arzneiform von Tramadol oder einem Tramadolsalz
AU741992B2 (en) * 1998-03-06 2001-12-13 Adare Pharmaceuticals S.R.L. Fast disintegrating tablets
EP1739072A1 (en) 2005-06-15 2007-01-03 Laboratorios Menarini S.A. Polymorphic forms of dexketoprofen trometamol, preparation and pharmaceutical compositions thereof
KR20080039400A (ko) 2005-07-07 2008-05-07 파남 컴퍼니스 인크. 고수용성 약물의 서방성 약학 조성물
ITMI20060983A1 (it) * 2006-05-18 2007-11-19 Formevet S P A Composizioni farmaceutiche veterinarie per il trattamento del dolore e dell'inifiamazione
BRPI0700133A (pt) * 2007-01-29 2008-09-16 Incrementha P D & I Pesquisa D composição farmacêutica compreendendo tramadol e cetoprofeno em combinação
WO2008150324A1 (en) * 2007-03-26 2008-12-11 Theraquest Biosciences, Inc. Subanalgesic doses of drug combinations
EP2177215A1 (en) * 2008-10-17 2010-04-21 Laboratorios Del. Dr. Esteve, S.A. Co-crystals of tramadol and NSAIDs
ES2356762B1 (es) * 2009-09-04 2011-11-24 Farmalider S.A. Composicion farmaceutica de ibuprofeno, tramadol y un aminoacido basico, procedimiento para su preparacion y utilizacion de la misma.

Also Published As

Publication number Publication date
AU2014218110B2 (en) 2018-08-09
PL2956129T3 (pl) 2018-09-28
UY35324A (es) 2014-08-29
RS57271B1 (sr) 2018-08-31
CN105007907A (zh) 2015-10-28
MA38335B1 (fr) 2017-12-29
DK2956129T3 (en) 2018-06-18
CR20150411A (es) 2015-12-07
WO2014124862A1 (en) 2014-08-21
SG11201506291UA (en) 2015-09-29
ES2672986T3 (es) 2018-06-19
ECSP15034660A (es) 2019-03-29
MA38335A1 (fr) 2016-12-30
JP6297068B2 (ja) 2018-03-20
CL2015002251A1 (es) 2016-02-05
LT2956129T (lt) 2018-06-11
IL240514B (en) 2019-10-31
TW201442703A (zh) 2014-11-16
AU2014218110A1 (en) 2015-08-27
KR20150115803A (ko) 2015-10-14
BR112015018952A2 (pt) 2017-07-18
JP2016507577A (ja) 2016-03-10
US20150374650A1 (en) 2015-12-31
MX353897B (es) 2018-02-01
NO2956129T3 (es) 2018-09-15
HK1216840A1 (zh) 2016-12-09
CU24310B1 (es) 2018-01-10
PE20151430A1 (es) 2015-10-13
GEP201706649B (en) 2017-03-27
NZ710967A (en) 2019-08-30
EA029709B1 (ru) 2018-05-31
SI2956129T1 (en) 2018-06-29
HUE038417T2 (hu) 2018-10-29
UA115684C2 (uk) 2017-12-11
AP2015008616A0 (en) 2015-07-31
PT2956129T (pt) 2018-06-14
BR112015018952B1 (pt) 2022-09-13
EP2956129B1 (en) 2018-04-18
KR102262408B1 (ko) 2021-06-08
ITMI20130210A1 (it) 2014-08-15
MY173102A (en) 2019-12-26
HRP20180974T1 (hr) 2018-08-10
CA2900979C (en) 2021-04-13
SA515360877B1 (ar) 2018-04-29
PH12015501766B1 (en) 2015-11-09
NI201500105A (es) 2015-09-10
TN2015000345A1 (en) 2017-01-03
MX2015010431A (es) 2015-10-05
IL240514A0 (en) 2015-10-29
PH12015501766A1 (en) 2015-11-09
TR201810114T4 (tr) 2018-08-27
CU20150081A7 (es) 2016-01-29
CA2900979A1 (en) 2014-08-21
EP2956129A1 (en) 2015-12-23
EA201591319A1 (ru) 2016-01-29
TWI642430B (zh) 2018-12-01
CN105007907B (zh) 2017-06-09
CY1120301T1 (el) 2019-07-10
US9949940B2 (en) 2018-04-24

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