AR094712A1 - Modificador de sabor dulce - Google Patents

Modificador de sabor dulce

Info

Publication number
AR094712A1
AR094712A1 ARP140100526A ARP140100526A AR094712A1 AR 094712 A1 AR094712 A1 AR 094712A1 AR P140100526 A ARP140100526 A AR P140100526A AR P140100526 A ARP140100526 A AR P140100526A AR 094712 A1 AR094712 A1 AR 094712A1
Authority
AR
Argentina
Prior art keywords
sweet flavor
flavor modifier
alkyl
heteroaryl
modifier
Prior art date
Application number
ARP140100526A
Other languages
English (en)
Inventor
Darmohusodo Vincent
Tachdjian Catherine
Petrovic Goran
Adamski-Werner Sara
Fotsing Joseph
Kimmich Rachel
Karanewsky Donald
Original Assignee
Senomyx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senomyx Inc filed Critical Senomyx Inc
Publication of AR094712A1 publication Critical patent/AR094712A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20Synthetic spices, flavouring agents or condiments
    • A23L27/205Heterocyclic compounds
    • A23L27/2056Heterocyclic compounds having at least two different hetero atoms, at least one being a nitrogen atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Seasonings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Reivindicación 1: Un compuesto que tiene la fórmula estructural (1) o una sal o solvato de esta; en donde R¹ y R² son independientemente alquilo C₁₋₄; o alternativamente, R¹ y R², junto con el átomo de carbono al cual están unidos, forman un cicloalquilo C₃₋₇; R es hidrógeno o alquilo C₁₋₆; y Het es heteroarilo o heteroarilo sustituido.
ARP140100526A 2013-02-19 2014-02-19 Modificador de sabor dulce AR094712A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361766652P 2013-02-19 2013-02-19

Publications (1)

Publication Number Publication Date
AR094712A1 true AR094712A1 (es) 2015-08-19

Family

ID=51351650

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP140100526A AR094712A1 (es) 2013-02-19 2014-02-19 Modificador de sabor dulce

Country Status (10)

Country Link
US (4) US9475803B2 (es)
AR (1) AR094712A1 (es)
BR (1) BR112015017912B1 (es)
CA (1) CA2897821A1 (es)
CL (1) CL2015002334A1 (es)
JO (2) JO3155B1 (es)
MX (1) MX362259B (es)
PE (1) PE20151994A1 (es)
TW (1) TWI639385B (es)
WO (1) WO2014130513A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
WO2010014666A2 (en) 2008-07-31 2010-02-04 Senomyx, Inc. Processes and intermediates for making sweet taste enhancers
RU2666534C2 (ru) 2012-08-06 2018-09-11 Сеномикс, Инк. Модификатор сладкого вкуса и аромата
JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
JP6949838B2 (ja) 2015-10-29 2021-10-13 フィルメニッヒ インコーポレイテッドFirmenich Incorporated 高甘味度甘味料
US10266861B2 (en) 2015-12-14 2019-04-23 E. I. Du Pont De Nemours And Company Production and composition of fructose syrup
US11751592B2 (en) 2016-04-06 2023-09-12 The Coca-Cola Company Sweetness and taste improvement of steviol glycoside or mogroside sweeteners
MX2019012940A (es) 2017-05-03 2019-12-16 Firmenich Incorporated Metodos para producir edulcorantes de alta intensidad.
SG11201909793YA (en) 2017-06-20 2019-11-28 Raqualia Pharma Inc AMIDE DERIVATIVES AS Nav1.7 and Nav1.8 BLOCKERS
EP3720295A4 (en) * 2017-12-08 2021-09-08 Chromocell Corporation TRYPTOPHANE DERIVATIVES AS SWEETENERS
US11945813B2 (en) 2018-08-07 2024-04-02 Firmenich Incorporated 5-substituted 4-amino-1H-benzo[c][1,2,6]thiadiazine 2,2-dioxides and formulations and uses thereof
CN109503410B (zh) * 2018-12-10 2021-12-03 安徽金禾实业股份有限公司 一种三氯蔗糖生产中溶剂dmf回收的方法
EP4040986A1 (en) * 2019-12-13 2022-08-17 Firmenich Incorporated Taste modifying compositions and uses thereof
EP4258895A1 (en) 2021-01-15 2023-10-18 Firmenich Incorporated Sweetener compostions comprising siamenoside i and uses thereof
WO2022155667A1 (en) 2021-01-15 2022-07-21 Firmenich Incorporated Sweetener compositions comprising mogrosides and uses thereof
JP2024514002A (ja) 2021-04-15 2024-03-27 ジボダン エス エー 味改変剤
JP2024524266A (ja) * 2021-06-23 2024-07-05 フイルメニツヒ ソシエテ アノニム ラクターゼを含むフレーバー修飾組成物
WO2023172415A1 (en) 2022-03-07 2023-09-14 Firmenich Incorporated Sweetener compositions
WO2023169995A1 (en) 2022-03-10 2023-09-14 Firmenich Sa Sweetener compositions
WO2023198436A2 (en) 2022-04-11 2023-10-19 Firmenich Sa Sweetener compositions
WO2024149700A1 (en) * 2023-01-12 2024-07-18 Firmenich Sa Process for preparation of sulfamoyl chloride

Family Cites Families (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB951651A (en) 1960-02-17 1964-03-11 Shell Res Ltd Substituted benzonitriles, their preparation and compositions containing them
US3278532A (en) 1964-07-06 1966-10-11 Sandoz Ag Dioxybenzothiadiazines
US3857972A (en) 1971-03-10 1974-12-31 Int Flavors & Fragrances Inc Flavoring with an oxocyclic pyrimidine
US3843804A (en) 1971-03-10 1974-10-22 Int Flavors & Fragrances Inc Novel flavoring compositions and processes
LU64388A1 (es) 1971-12-02 1973-07-16
FI54312C (fi) 1972-05-09 1978-11-10 Sumitomo Chemical Co Foerfarande foer framstaellning av tieno-(2,3-d)pyrimidinderivat med avsoendring av urinsyra i urin utoekande
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3960860A (en) 1973-01-08 1976-06-01 International Flavors & Fragrances Inc. 2-Methyl-5,7-dihydrothieno-[3,4d]-pyrimidine
US4036837A (en) 1973-03-23 1977-07-19 American Home Products Corporation 2 Alkoxyoxamoyl-pyrazines
US3966965A (en) 1973-03-23 1976-06-29 American Home Products Corporation Oxamic acid derivatives for the prevention of immediate type hypersensitivity reactions
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
GB1570494A (en) 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
US4137325A (en) 1977-03-17 1979-01-30 American Home Products Corporation Antisecretory oxamic acid esters
ZA782648B (en) 1977-05-23 1979-06-27 Ici Australia Ltd The prevention,control or eradication of infestations of ixodid ticks
JPS5951290B2 (ja) 1978-07-13 1984-12-13 松下電器産業株式会社 調理器
ES472163A1 (es) 1978-07-28 1979-03-16 Consejo Superior Investigacion Ÿun nuevo procedimiento para la obtencion de 5,5-dioxido de 7-amino-2h-4h-vic-triazolo (4,5-c) (1,2,6) tiadiazinaÿ
IE51802B1 (en) 1979-12-03 1987-04-01 Fujisawa Pharmaceutical Co Quinazoline derivatives,processes for their preparation and pharmaceutical compositions containing them
JPS5951290A (ja) 1982-09-14 1984-03-24 Dai Ichi Seiyaku Co Ltd ベンゾチエノイミダゾピリミジンジオン化合物
ES531159A0 (es) 1984-03-30 1985-09-01 Consejo Superior Investigacion Procedimiento para la preparacion de aminociclotiadiazinas
GB8504253D0 (en) 1985-02-19 1985-03-20 Ici Plc Electrostatic spraying apparatus
US4672116A (en) 1985-12-20 1987-06-09 Ortho Pharmaceutical Corporation Substituted 5,6-dialkoxyquinazoline derivatives
JPS6387959A (ja) 1986-10-01 1988-04-19 Sanyo Kokusaku Pulp Co Ltd ステビア甘味料の呈味性改善法
US4960870A (en) 1987-02-11 1990-10-02 Ciba-Geigy Corporation Heavy metal complex azo dyes containing a benzothiophene-1,1-dioxide, 2,1-benzothiazine-2,2-dioxide, 1,4-benzothiazine-1,1-dioxide or thienopyridine-1,1-dioxide coupling component
JPH0655730B2 (ja) 1987-07-17 1994-07-27 ザ ヌトラスウィート カンパニー 強力甘味剤
US5380541A (en) 1987-08-07 1995-01-10 Tate & Lyle Public Limited Company Sucralose compositions
DE3815221C2 (de) 1988-05-04 1995-06-29 Gradinger F Hermes Pharma Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen
JPH02238856A (ja) 1989-03-14 1990-09-21 Mitajiri Kagaku Kogyo Kk ミラクリンを有効成分とする矯味・調味料及びこれを含有する飲食品
US5192785A (en) 1989-09-03 1993-03-09 A. H. Robins Company, Incorporated Sulfamates as antiglaucoma agents
US5504095A (en) 1990-09-19 1996-04-02 Pfizer Inc. Aminobenzosultam derivatives as lipoxygenase inhibitors
US5698155A (en) 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
IL102764A0 (en) 1991-08-16 1993-01-31 Merck & Co Inc Quinazoline derivatives,and pharmaceutical compositions containing them
PT100905A (pt) 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
GB9127188D0 (en) 1991-12-21 1992-02-19 Smithkline Beecham Plc Novel compounds
KR970010069B1 (ko) 1992-08-24 1997-06-20 주식회사 럭키 신규 세팔로스포린계 항생제 및 이의 제조방법
WO1996028205A1 (en) 1995-03-14 1996-09-19 Siemens Aktiengesellschaft Ultrasonic atomizer device with removable precision dosing unit
JP3585127B2 (ja) 1995-03-14 2004-11-04 シーメンス アクチエンゲゼルシヤフト 超音波噴霧システム
US6046206A (en) 1995-06-07 2000-04-04 Cell Pathways, Inc. Method of treating a patient having a precancerous lesions with amide quinazoline derivatives
DE19632423A1 (de) 1996-08-12 1998-02-19 Merck Patent Gmbh Thienopyrimidine
DE59711346D1 (de) 1996-12-20 2004-04-01 Nutrinova Gmbh Verfahren zur verstärkung der süsskraft und zur geschmacksverbesserung einer mischung hochintensiver süssstoffe
KR100220953B1 (ko) 1996-12-31 1999-10-01 김영환 아미드 또는 이미드를 도입한 ArF 감광막 수지
GB9711650D0 (en) 1997-06-05 1997-07-30 Pfizer Ltd Compounds useful in therapy
US5954047A (en) 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
US5990117A (en) 1998-04-15 1999-11-23 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to quinazoline derivatives
AU4317399A (en) 1998-05-28 1999-12-13 Parker Hughes Institute Quinazolines for treating brain tumor
US7588900B2 (en) 2001-07-03 2009-09-15 The Regents Of The University Of California Mammalian sweet and amino acid heterodimeric taste receptors
US6169118B1 (en) 1998-11-12 2001-01-02 Block Drug Company, Inc. Flavor blend for masking unpleasant taste of zinc compounds
WO2000071524A1 (en) 1999-05-19 2000-11-30 Smithkline Beecham Plc 2-nh-pyridones and pyrimidones as mrs inhibitors
GB9915995D0 (en) 1999-07-09 1999-09-08 Ahmed S Non-steroidal sulphamate compounds for use as oestrone sulphatase inhibitors
JP3523166B2 (ja) 1999-09-02 2004-04-26 高砂香料工業株式会社 食品香料劣化防止剤、食品香料劣化防止方法およびその食品香料劣化防止剤を含有する食品
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
WO2001077676A1 (en) 2000-04-07 2001-10-18 Senomyx, Inc. T2r taste receptors and genes encoding same
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
CN1234691C (zh) 2001-03-02 2006-01-04 住友化学工业株式会社 喹啉-3-羧酸化合物的制备方法
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
EP2003451B1 (en) 2001-06-26 2012-05-30 Senomyx, Inc. T1r1-t1r3 hetero-oligomeric umami taste receptors and cell lines that express said receptors and use thereof for identification of umami taste compounds
US20060134693A1 (en) 2001-07-06 2006-06-22 Guy Servant Olfactory cyclic nucleotide-gated channel cell-based assays to identify T1R and T2R taste modulators
CN100442996C (zh) 2001-07-19 2008-12-17 三荣源有限公司 味道改良组合物及其应用
AU2002336462A1 (en) 2001-09-06 2003-03-24 Millennium Pharmaceuticals, Inc. Piperazine and homopiperazine compounds
DE60215699T2 (de) 2001-12-14 2007-08-30 Merck Frosst Canada Ltd., Kirkland Quinolinone als prostaglandin rezeptor liganden
WO2003055866A1 (en) 2001-12-21 2003-07-10 Bayer Pharmaceuticals Corporation Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
GB0206033D0 (en) 2002-03-14 2002-04-24 Pfizer Ltd Compounds useful in therapy
AU2003261354A1 (en) 2002-08-02 2004-02-23 The Regents Of The University Of California New uses for inhibitors of inosine monophosphate dehydrogenase
GB0230015D0 (en) 2002-12-23 2003-01-29 Novartis Ag Organic compounds
DE10324548A1 (de) 2003-05-28 2004-12-16 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Diätisches Lebensmittel bei einer gewichtskontrollierenden bzw. gewichtsreduzierenden Ernährung
BRPI0413347A (pt) 2003-08-06 2006-10-10 Senomyx Inc novos sabores, modificadores de sabor, agentes de sabor, realçadores de sabor, agentes de sabor e/ou realçadores umami ou doces, e utilização correspondente
WO2005016889A1 (en) 2003-08-08 2005-02-24 Virginia Commonwealth University Compounds having antiestrogenic and tissue selective estrogenic properties
CA2558683A1 (en) 2004-03-05 2005-09-22 Sunil Srivastava High-intensity sweetener-polyol compositions
EP1753864A2 (en) 2004-04-14 2007-02-21 Monell Chemical Senses Center Taste receptors of the t1r family from domestic dog
JP5001150B2 (ja) 2004-06-08 2012-08-15 ファミリーズ オブ スパイナル マスキュラー アトロフィー 脊髄性筋萎縮症のための2,4−ジアミノキナゾリン
US20060045953A1 (en) 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
EP1808083B1 (en) 2004-10-15 2012-12-05 Ajinomoto Co., Inc. Sweetener composition
US20080261823A1 (en) 2004-12-10 2008-10-23 Yitzhak Tor Fluorescent Nucleoside Analogs That Mimic Naturally Occurring Nucleosides
ES2324231T3 (es) 2004-12-17 2009-08-03 F. Hoffmann-La Roche Ag Derivados de tieno-piridina como intensificadores alostericos de gaba-b.
JP4734346B2 (ja) 2005-02-04 2011-07-27 セノミックス インコーポレイテッド 連結ヘテロアリール部分を含む化合物、ならびに食用組成物のための新規なうまみフレーバー改変剤、味物質および味覚増強剤としての使用
WO2006084184A2 (en) 2005-02-04 2006-08-10 Senomyx, Inc. Molecules comprising linked organic moieties as flavor modifiers for comestible compositions
US8796441B2 (en) 2005-04-13 2014-08-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Human sweet and umami taste receptor variants
US20080176830A1 (en) 2005-04-14 2008-07-24 Adams Nicholas D Compounds, Compositions, and Methods
JP2008545688A (ja) 2005-05-25 2008-12-18 ワイス 置換3−シアノキノリン並びにその中間体を合成する方法
AR055329A1 (es) 2005-06-15 2007-08-15 Senomyx Inc Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor
JP2007007591A (ja) 2005-07-01 2007-01-18 Mikuni Corp 電解水及びその製造方法
EP1922311A2 (en) 2005-09-09 2008-05-21 Brystol-Myers Squibb Company Acyclic ikur inhibitors
CN101605810B (zh) 2005-10-20 2013-07-17 塞诺米克斯公司 嵌合的人甜味-鲜味和鲜味-甜味受体
US8506956B2 (en) 2005-10-31 2013-08-13 Kaneka Corporation Method for stabilizing reduced coenzyme Q10
JP2009520784A (ja) 2005-12-22 2009-05-28 アストラゼネカ アクチボラグ キナゾリン誘導体、その製造方法および抗癌剤としてのその使用
AU2007271486A1 (en) 2006-07-05 2008-01-10 Merck Patent Gmbh Sulfamate benzothiophene derivatives
BRPI0716053A2 (pt) 2006-08-22 2013-08-06 Redpoint Bio Corp compostos heterocÍclicos como promotores de adoÇantes
US7928111B2 (en) 2007-06-08 2011-04-19 Senomyx, Inc. Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
US8633186B2 (en) 2007-06-08 2014-01-21 Senomyx Inc. Modulation of chemosensory receptors and ligands associated therewith
US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
WO2009006722A1 (en) 2007-07-12 2009-01-15 Mehrzad Gomari Paper-free local flyer advertising (a technology method of localized internet advertising)
RU2511315C2 (ru) * 2008-07-31 2014-04-10 Синомикс, Инк. Композиции, содержащие усилители сладкого вкуса, и способы их получения
WO2010014666A2 (en) 2008-07-31 2010-02-04 Senomyx, Inc. Processes and intermediates for making sweet taste enhancers
EP2552207B1 (en) 2010-04-02 2019-08-21 Firmenich Incorporated Sweet flavor modifier
EP2587939B1 (en) 2010-06-29 2014-03-19 Firmenich SA Active ingredient delivery system
BR112013003332B1 (pt) 2010-08-12 2018-11-13 Senomyx, Inc. método para melhorar a estabilidade de intensificador de doce e composição contendo intensificador de doce estabilizado
EP2629617A4 (en) 2010-10-19 2014-08-27 Elcelyx Therapeutics Inc THERAPIES BASED ON CHEMOSOUS RECEPTOR LIGANDS
EP2695899A1 (de) 2012-08-06 2014-02-12 Basf Se Polyharnstoff-Elastomere mit erhöhter Chemikalienbeständigkeit
RU2666534C2 (ru) 2012-08-06 2018-09-11 Сеномикс, Инк. Модификатор сладкого вкуса и аромата
JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
KR102265636B1 (ko) 2013-03-13 2021-06-16 디에스엠 뉴트리셔널 프라덕츠 아게 우레아/오일 복합체로부터 우레아 및 오일의 회수

Also Published As

Publication number Publication date
CL2015002334A1 (es) 2016-05-27
JO3287B1 (ar) 2018-09-16
BR112015017912A2 (pt) 2017-07-11
MX2015010559A (es) 2015-11-16
US20150257422A1 (en) 2015-09-17
US9000151B2 (en) 2015-04-07
MX362259B (es) 2019-01-09
JO3155B1 (ar) 2017-09-20
BR112015017912B1 (pt) 2021-08-31
US20140235624A1 (en) 2014-08-21
PE20151994A1 (es) 2016-01-29
WO2014130513A1 (en) 2014-08-28
US20170029416A1 (en) 2017-02-02
US9695162B2 (en) 2017-07-04
US9371317B2 (en) 2016-06-21
TWI639385B (zh) 2018-11-01
TW201440667A (zh) 2014-11-01
CA2897821A1 (en) 2014-08-28
US20150376176A1 (en) 2015-12-31
US9475803B2 (en) 2016-10-25

Similar Documents

Publication Publication Date Title
AR094712A1 (es) Modificador de sabor dulce
CY1120635T1 (el) Βενζαμιδια αμινοετεροαρυλιου ως αναστολεις κινασης
CR20150418A (es) Compuestos de tetrahidropirrolotiazina
EA201591503A1 (ru) Производные нафтиридина, полезные в качестве антагонистов альфа-v-бета-6 интегрина
GB2528586B (en) Treatment of a subterranean formation with composition including a microorganism or compound generated by the same
BR112017006253A2 (pt) novos compostos
RS54730B1 (sr) Inhibitori beta sekretaze
UY35333A (es) Compuestos de azabencimidazol
AR097866A1 (es) Derivados de 4-azaindol
EA201690894A1 (ru) Феноксиэтилы
AR094812A1 (es) Derivado de piridina monocíclico como inhibidor del fgfr
AR095523A1 (es) Derivados piridin-4-ilo
EA201591349A1 (ru) Способ получения вортиоксетина
AR089623A1 (es) Inhibidores de iap
EA201591915A1 (ru) Соединения феноксиэтил дигидро-1h-изохинолина
AR097253A1 (es) Derivado de pirazolilpirazol sustituido y el uso del mismo como herbicida
AR089753A1 (es) Derivados de amida heterociclicos como antagonistas del receptor p2x7
RS54716B1 (en) HETEROCYCLIC COMPOUNDS AND THEIR APPLICATIONS
EA201491852A1 (ru) Новые пиразольные соединения
AR098269A1 (es) Poliéster terminado en epoxi
AR096161A1 (es) Derivados de triazina
AR093827A1 (es) Agentes antibacterianos de tetrahidroquinolina triciclica
EA201690593A1 (ru) Новые соединения мочевины
EA201690908A1 (ru) Пиразолопиримидиновые соединения
AR102298A1 (es) Compuesto heterocíclico fusionado

Legal Events

Date Code Title Description
FB Suspension of granting procedure