AR094290A1 - Composiciones y metodos para la administracion transdermica de agentes antiinflamatorios no esteroideos - Google Patents
Composiciones y metodos para la administracion transdermica de agentes antiinflamatorios no esteroideosInfo
- Publication number
- AR094290A1 AR094290A1 ARP130105040A ARP130105040A AR094290A1 AR 094290 A1 AR094290 A1 AR 094290A1 AR P130105040 A ARP130105040 A AR P130105040A AR P130105040 A ARP130105040 A AR P130105040A AR 094290 A1 AR094290 A1 AR 094290A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- polymeric matrix
- compositions
- matrix comprises
- occlusive
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Composiciones para la administración transdérmica de agentes antiinflamatorios no esteroideos (NSAID) en una forma flexible limitada. Las composiciones comprenden una matriz polimérica que incluye un NSAID y una matriz polimérica que comprende una mezcla de polímeros de silicona y acrílicos. Se divulga también un material de soporte oclusivo y flexible. También se describen métodos para hacer y usar las composiciones y soportes. Reivindicación 7: La composición de cualquiera de las reivindicaciones precedentes, caracterizada porque la matriz polimérica comprende aproximadamente entre 3% y 5% p/p de flurbiprofeno. Reivindicación 8: La composición de cualquiera de las reivindicaciones precedentes, caracterizada porque la matriz polimérica comprende entre aproximadamente 4 y 5% p/p de polímero acrílico. Reivindicación 9: La composición de cualquiera de las reivindicaciones precedentes, caracterizada porque la matriz polimérica comprende aproximadamente 5% p/p de copolímero acrílico en bloque. Reivindicación 10: La composición de cualquiera de las reivindicaciones precedentes, caracterizada porque la matriz polimérica comprende hasta aproximadamente 1% p/p de copolímero en bloque de estireno-isoprenoestireno. Reivindicación 11: La composición de cualquiera de las reivindicaciones precedentes, caracterizada porque la matriz polimérica comprende al menos aproximadamente 80% p/p de polímero de silicona. Reivindicación 14: La composición de cualquiera de las reivindicaciones precedentes, caracterizada porque el sistema realiza la administración del NSAID a lo largo de un periodo de tiempo de al menos 24 horas. Reivindicación 18: La composición de cualquiera de las reivindicaciones 16 a 17, caracterizada porque la capa de soporte oclusiva flexible comprende un material de soporte de tela recubierto con un recubrimiento oclusivo. Reivindicación 19: La composición de la reivindicación 18, caracterizada porque el recubrimiento oclusivo comprende poliisobutileno y/o copolímeros en bloque de estireno-isopreno-estireno (SIS).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261747039P | 2012-12-28 | 2012-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR094290A1 true AR094290A1 (es) | 2015-07-22 |
Family
ID=49956516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130105040A AR094290A1 (es) | 2012-12-28 | 2013-12-27 | Composiciones y metodos para la administracion transdermica de agentes antiinflamatorios no esteroideos |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20140188056A1 (es) |
| EP (1) | EP2938334A1 (es) |
| JP (1) | JP6550337B2 (es) |
| KR (1) | KR20150103077A (es) |
| AR (1) | AR094290A1 (es) |
| AU (1) | AU2013370290A1 (es) |
| CA (1) | CA2896336C (es) |
| HK (1) | HK1216610A1 (es) |
| IL (1) | IL239602A0 (es) |
| MX (1) | MX2015008284A (es) |
| PH (1) | PH12015501463A1 (es) |
| TW (1) | TW201438767A (es) |
| WO (1) | WO2014106009A1 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016505006A (ja) | 2012-12-28 | 2016-02-18 | ノーヴェン ファーマシューティカルズ インコーポレイテッド | レボノルゲストレル及びエチニルエストラジオール用の経皮薬物送達システム |
| EP2938335B1 (en) | 2012-12-28 | 2021-03-17 | Noven Pharmaceuticals, INC. | Multi-polymer compositions for transdermal drug delivery |
| WO2014159582A1 (en) | 2013-03-14 | 2014-10-02 | Noven Pharmaceuticals, Inc | Amphetamine transdermal compositions with acrylic block copolymer |
| AR095260A1 (es) | 2013-03-15 | 2015-09-30 | Noven Pharma | Composiciones de anfetaminas transdérmicas estables y métodos de fabricación |
| AR095259A1 (es) | 2013-03-15 | 2015-09-30 | Noven Pharma | Composiciones y métodos para la administración transdérmica de fármacos de amina terciaria |
| AU2015296807A1 (en) * | 2014-07-31 | 2017-03-09 | Noven Pharmaceuticals, Inc. | Silicone-containing acrylic polymers for transdermal drug delivery compositions |
| US10406116B2 (en) | 2015-02-06 | 2019-09-10 | Noven Pharmaceuticals, Inc. | Pressure-sensitive adhesives for transdermal drug delivery |
| JP6807848B2 (ja) | 2015-02-06 | 2021-01-06 | ノーヴェン ファーマシューティカルズ インコーポレイテッド | 経皮薬物送達のための感圧粘着剤 |
| WO2017087354A1 (en) * | 2015-11-16 | 2017-05-26 | Noven Pharmaceuticals, Inc. | Stretchable backing layers for transdermal drug delivery systems |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4112177A (en) * | 1978-01-23 | 1978-09-05 | Minnesota Mining And Manufacturing Company | Porous adhesive tape |
| JPS5843368B2 (ja) * | 1980-10-30 | 1983-09-27 | 日東電工株式会社 | 消炎鎮痛貼付剤 |
| US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US5656286A (en) * | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| AU2514292A (en) * | 1991-08-27 | 1993-03-16 | Cygnus Therapeutic Systems | Transdermal formulations for administering prazosin |
| JP3542814B2 (ja) * | 1993-03-09 | 2004-07-14 | 積水化学工業株式会社 | 消炎鎮痛貼付剤 |
| JPH08509222A (ja) * | 1993-04-22 | 1996-10-01 | ミネソタ マイニング アンド マニュファクチャリング カンパニー | 経皮抗炎症性組成物 |
| JPH08295624A (ja) * | 1995-04-26 | 1996-11-12 | Read Chem Kk | プラスター基剤、その製造方法、該基剤を使用した外用貼 付剤 |
| US5976566A (en) * | 1997-08-29 | 1999-11-02 | Macrochem Corporation | Non-steroidal antiinflammtory drug formulations for topical application to the skin |
| DE19830649C2 (de) * | 1998-07-09 | 2003-04-10 | Lohmann Therapie Syst Lts | Topisches Pflaster mit nichtsteroidalen Antirheumatika mit Säuregruppe |
| JP2000281570A (ja) * | 1999-03-30 | 2000-10-10 | Nichiban Co Ltd | 経皮投与用貼付剤 |
| US7063859B1 (en) * | 1999-04-28 | 2006-06-20 | Noven Pharmaceuticals, Inc. | Barrier film lined backing layer composition and method for topical administration of active agents |
| DE10025890A1 (de) * | 2000-05-25 | 2001-11-29 | Euro Celtique Sa | Dosierung von transdermalen Arzneimittelsystemen |
| ITMI20020798A1 (it) * | 2002-04-15 | 2003-10-15 | F T Holding S A | Cerotti transdermici a matrice adesiva siliconica stabilizzati con copolimeri metacrilici |
| AU2003268376A1 (en) * | 2002-08-30 | 2004-11-26 | Watson Pharmaceuticals, Inc. | Transdermal delivery systems and methods |
| JP2007509951A (ja) * | 2003-10-28 | 2007-04-19 | ノーヴェン ファーマシューティカルズ インコーポレイテッド | 経皮的なドラッグデリバリーシステムにおける医薬品の損失及び送達を制御するための組成物及び方法 |
| WO2006041911A2 (en) * | 2004-10-08 | 2006-04-20 | Noven Pharmaceuticals, Inc. | Device transdermal administration of drugs including acrylic polymers |
| US20080089925A1 (en) * | 2004-11-10 | 2008-04-17 | Masato Wakamatsu | Drug for External Use and Adhesive Patch |
| KR100663163B1 (ko) * | 2005-10-24 | 2007-01-02 | (주)아모레퍼시픽 | 비스테로이드성 소염진통제를 함유하는 경피 투여 제제 |
| JP2010508289A (ja) * | 2006-10-27 | 2010-03-18 | ノーヴェン ファーマシューティカルズ インコーポレイテッド | ケトプロフェン極性誘導体の経皮的送達 |
| JP5318639B2 (ja) * | 2009-04-08 | 2013-10-16 | 株式会社ウェーブロック・アドバンスト・テクノロジー | 貼付剤用支持体、及び、貼付剤 |
-
2013
- 2013-12-27 MX MX2015008284A patent/MX2015008284A/es unknown
- 2013-12-27 US US14/141,946 patent/US20140188056A1/en not_active Abandoned
- 2013-12-27 CA CA2896336A patent/CA2896336C/en active Active
- 2013-12-27 KR KR1020157019836A patent/KR20150103077A/ko not_active Application Discontinuation
- 2013-12-27 JP JP2015550783A patent/JP6550337B2/ja active Active
- 2013-12-27 TW TW102148884A patent/TW201438767A/zh unknown
- 2013-12-27 AR ARP130105040A patent/AR094290A1/es unknown
- 2013-12-27 WO PCT/US2013/077927 patent/WO2014106009A1/en active Application Filing
- 2013-12-27 AU AU2013370290A patent/AU2013370290A1/en not_active Abandoned
- 2013-12-27 EP EP13821401.0A patent/EP2938334A1/en not_active Withdrawn
-
2015
- 2015-06-23 IL IL239602A patent/IL239602A0/en unknown
- 2015-06-24 PH PH12015501463A patent/PH12015501463A1/en unknown
-
2016
- 2016-04-19 HK HK16104490.9A patent/HK1216610A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20140188056A1 (en) | 2014-07-03 |
| IL239602A0 (en) | 2015-08-31 |
| JP6550337B2 (ja) | 2019-07-24 |
| EP2938334A1 (en) | 2015-11-04 |
| WO2014106009A1 (en) | 2014-07-03 |
| HK1216610A1 (zh) | 2016-11-25 |
| PH12015501463A1 (en) | 2015-09-21 |
| MX2015008284A (es) | 2015-12-03 |
| JP2016504367A (ja) | 2016-02-12 |
| AU2013370290A1 (en) | 2015-07-16 |
| KR20150103077A (ko) | 2015-09-09 |
| TW201438767A (zh) | 2014-10-16 |
| CA2896336A1 (en) | 2014-07-03 |
| CA2896336C (en) | 2021-10-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |