PE20060973A1 - Administracion transdermica de drogas basada en el tamano de los cristales - Google Patents

Administracion transdermica de drogas basada en el tamano de los cristales

Info

Publication number
PE20060973A1
PE20060973A1 PE2005001197A PE2005001197A PE20060973A1 PE 20060973 A1 PE20060973 A1 PE 20060973A1 PE 2005001197 A PE2005001197 A PE 2005001197A PE 2005001197 A PE2005001197 A PE 2005001197A PE 20060973 A1 PE20060973 A1 PE 20060973A1
Authority
PE
Peru
Prior art keywords
active principle
drug administration
crystal size
transdermal drug
crystals
Prior art date
Application number
PE2005001197A
Other languages
English (en)
Inventor
Viet Nguyen
Original Assignee
Noven Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noven Pharma filed Critical Noven Pharma
Publication of PE20060973A1 publication Critical patent/PE20060973A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UN SISTEMA DE TRANSMISION TRANSDERMICA QUE COMPRENDE: A) UN ADHESIVO QUE COMPRENDE UNO O MAS DE UN POLIMERO A BASE DE CAUCHO, ACRILICO O POLISILOXANO TALES COMO POLIISOBUTILENO, POLIBUTILENO, POLIISOPRENO NATURAL, ENTRE OTROS EN UNA CANTIDAD COMPRENDIDA ENTRE 5 A 97% EN PESO DEL SISTEMA Y B) UN PRINCIPIO ACTIVO SELECCIONADO ENTRE CLONIDINA, ESTRADIOL, ESCOPOLAMINA, ENTRE OTROS; EN UNA CANTIDAD COMPRENDIDA ENTRE 0,1 A 50% EN PESO DEL SISTEMA. DICHO SISTEMA COMPRENDE 3 PORCIONES DONDE EN LA PRIMERA PORCION EL PRINCIPIO ACTIVO ESTA SOLUBLE, EN LA SEGUNDA SE PRESENTA EN FORMA DE CRISTALES CON TAMANO DE PARTICULA ENTRE 1 um a 200 um Y EN LA TERCERA COMPRENDE CRISTALES CON TAMANO DE PARTICULA ENTRE 100 um a 2000 um. DICHO SISTEMA PROPORCIONA PERFILES DE LIBERACION DE PRINCIPIO ACTIVO DE ORDEN CERO DURANTE UN PERIODO DE TIEMPO PROLONGADO DE HASTA 7 DIAS O MAS
PE2005001197A 2004-10-08 2005-10-10 Administracion transdermica de drogas basada en el tamano de los cristales PE20060973A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61756104P 2004-10-08 2004-10-08

Publications (1)

Publication Number Publication Date
PE20060973A1 true PE20060973A1 (es) 2006-11-08

Family

ID=36148870

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2005001197A PE20060973A1 (es) 2004-10-08 2005-10-10 Administracion transdermica de drogas basada en el tamano de los cristales

Country Status (5)

Country Link
US (2) US8246976B2 (es)
AR (1) AR051585A1 (es)
PE (1) PE20060973A1 (es)
TW (1) TW200616589A (es)
WO (1) WO2006041908A2 (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006041907A2 (en) * 2004-10-08 2006-04-20 Noven Pharmaceuticals, Inc. Transdermal delivery of estradiol
US7888422B2 (en) * 2005-11-09 2011-02-15 Mylan Technologies Inc. Long-wearing removable pressure sensitive adhesive
CN101528830A (zh) 2006-07-10 2009-09-09 麦德医像公司 超弹性环氧水凝胶
ES2657887T3 (es) * 2006-07-14 2018-03-07 Hisamitsu Pharmaceutical Co., Inc. Preparación adhesiva
GB2443928A (en) * 2006-11-08 2008-05-21 Regen Therapeutics Plc Transdermal pharmaceutical composition comprising Zolpidem
US7829116B2 (en) 2006-11-14 2010-11-09 Momentive Performance Materials Inc. Adhesive-forming composition and blend of adhesives obtained therefrom
US7976951B2 (en) 2006-11-14 2011-07-12 Momentive Performance Materials Inc. Laminate containing an adhesive-forming composition
WO2008150120A1 (en) * 2007-06-08 2008-12-11 Samyang Corporation Matrix-type transdermal drug delivery system and preparation method thereof
HU227970B1 (en) * 2007-07-10 2012-07-30 Egis Gyogyszergyar Nyrt Pharmaceutical compositions containing silicones of high volatility
US9017301B2 (en) * 2007-09-04 2015-04-28 Mylan Technologies, Inc. Transdermal drug delivery systems comprising a coated release liner
EP2227635A2 (en) 2007-12-03 2010-09-15 Medipacs, Inc. Fluid metering device
CA2711774C (en) 2008-01-28 2016-05-24 Teikoku Seiyaku Co., Ltd. Fentanyl-containing patch for external use
US9238102B2 (en) 2009-09-10 2016-01-19 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
US20110172645A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US20110172639A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Device and method for delivery of microneedle to desired depth within the skin
US20110172609A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
WO2012060431A1 (ja) * 2010-11-02 2012-05-10 積水メディカル株式会社 貼付剤
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
CA2906274A1 (en) 2012-03-14 2013-09-19 Medipacs, Inc. Smart polymer materials with excess reactive molecules
US10045935B2 (en) 2012-07-31 2018-08-14 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
US10045965B2 (en) 2012-07-31 2018-08-14 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
US11154535B2 (en) 2012-07-31 2021-10-26 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
AR094289A1 (es) 2012-12-28 2015-07-22 Noven Pharma Sistemas de administracion transdermica de farmacos para levonorgestrel y etinil estradiol
MX366230B (es) 2012-12-28 2019-07-03 Noven Pharma Composiciones multipolimericas para liberación transdermica de farmaco.
US10221283B2 (en) * 2013-01-18 2019-03-05 Georgetown University Amino-substituted polysiloxanes combined with polymerizable and unpolymerizable organic acids
US11337936B2 (en) 2013-03-14 2022-05-24 Noven Pharmaceuticals, Inc. Amphetamine transdermal compositions with acrylic block copolymer
AR095260A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones de anfetaminas transdérmicas estables y métodos de fabricación
AR095259A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones y métodos para la administración transdérmica de fármacos de amina terciaria
WO2015095533A1 (en) * 2013-12-18 2015-06-25 Massachusetts Institute Of Technology Polymer matrices for controlling crystallization
AU2015296807A1 (en) * 2014-07-31 2017-03-09 Noven Pharmaceuticals, Inc. Silicone-containing acrylic polymers for transdermal drug delivery compositions
MX2017011349A (es) * 2015-03-04 2018-06-27 Noven Pharma Fluidos de silicona oligomericos/polimericos para uso en sistemas transdermicos de suministro de farmaco.
EP3267982A4 (en) * 2015-03-13 2018-11-07 Amneal Pharmaceuticals LLC Fentanyl transdermal delivery system
EP3383374A4 (en) * 2015-11-30 2019-07-24 Elliptical Therapeutics, LLC SYSTEMS AND METHODS OF TRANSDERMAL DRUG DELIVERY
US20200131409A1 (en) 2017-04-17 2020-04-30 3M Innovative Properties Company Blended block copolymer/silicone pressure sensitive adhesives
JP6704514B2 (ja) * 2017-04-25 2020-06-03 久光製薬株式会社 貼付剤
WO2019113470A1 (en) * 2017-12-08 2019-06-13 Teikoku Pharma Usa, Inc. Naloxone transdermal delivery devices and methods for using the same
US11096902B1 (en) 2021-05-07 2021-08-24 King Abdulaziz University Transdermal film formulations and methods of use

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5843368B2 (ja) 1980-10-30 1983-09-27 日東電工株式会社 消炎鎮痛貼付剤
US4559222A (en) 1983-05-04 1985-12-17 Alza Corporation Matrix composition for transdermal therapeutic system
US4585836A (en) 1984-10-29 1986-04-29 Dow Corning Corporation Silicone pressure-sensitive adhesive process and product with improved lap-shear stability-II
US4655767A (en) 1984-10-29 1987-04-07 Dow Corning Corporation Transdermal drug delivery devices with amine-resistant silicone adhesives
US4591622A (en) 1984-10-29 1986-05-27 Dow Corning Corporation Silicone pressure-sensitive adhesive process and product thereof
US4584355A (en) 1984-10-29 1986-04-22 Dow Corning Corporation Silicone pressure-sensitive adhesive process and product with improved lap-shear stability-I
US4858836A (en) * 1986-12-12 1989-08-22 Murata Kikai Kabushiki Kaisha Yarn end finding device
US5474783A (en) 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US4994267A (en) 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
US5656286A (en) 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5446070A (en) 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US4994278A (en) 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Breathable backing
JPH0653277A (ja) * 1992-06-04 1994-02-25 Lsi Logic Corp 半導体装置アセンブリおよびその組立方法
US5762952A (en) 1993-04-27 1998-06-09 Hercon Laboratories Corporation Transdermal delivery of active drugs
US5474787A (en) 1994-10-21 1995-12-12 The Wm. Wrigley Jr. Company Chewing gum containing a lecithin/glycerol triacetate blend
EP1021204B1 (en) 1997-09-26 2005-12-28 Noven Pharmaceuticals, Inc. Bioadhesive compositions and methods for topical administration of active agents
ES2237415T5 (es) * 1999-01-14 2008-12-16 Noven Pharmaceuticals, Inc. Composiciones dermicas.
US20010033858A1 (en) 2000-02-29 2001-10-25 Jie Zhang Transdermal drug patch
DE10034673C1 (de) * 2000-07-17 2002-04-25 Medac Klinische Spezialpraep Dermales Applikationssystem für Aminolävulinsäure und seine Verwendung
WO2003030872A2 (en) * 2001-10-12 2003-04-17 Elan Pharma International Ltd. Compositions having a combination of particles for immediate release and for controlled release
US20050069591A1 (en) * 2003-09-30 2005-03-31 Howard Bernstein Injectable, oral, or topical sustained release pharmaceutical formulations

Also Published As

Publication number Publication date
US20060078603A1 (en) 2006-04-13
AR051585A1 (es) 2007-01-24
TW200616589A (en) 2006-06-01
US8277838B2 (en) 2012-10-02
US20110091511A1 (en) 2011-04-21
WO2006041908A2 (en) 2006-04-20
WO2006041908A3 (en) 2006-07-20
US8246976B2 (en) 2012-08-21

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