CL2009000275A1 - Compuestos derivados de furo [3,2-c]piridina y tieno [3,2-c] piridina; composicion farmaceutica que los comprende; y su uso en el tratamiento del cancer. - Google Patents

Compuestos derivados de furo [3,2-c]piridina y tieno [3,2-c] piridina; composicion farmaceutica que los comprende; y su uso en el tratamiento del cancer.

Info

Publication number
CL2009000275A1
CL2009000275A1 CL2009000275A CL2009000275A CL2009000275A1 CL 2009000275 A1 CL2009000275 A1 CL 2009000275A1 CL 2009000275 A CL2009000275 A CL 2009000275A CL 2009000275 A CL2009000275 A CL 2009000275A CL 2009000275 A1 CL2009000275 A1 CL 2009000275A1
Authority
CL
Chile
Prior art keywords
pyridine
furo
thieno
cancer
treatment
Prior art date
Application number
CL2009000275A
Other languages
English (en)
Inventor
Li An-Hu
J Mulvihill Mark
Wang Ti
G Steining Arno
Wang Jing
Weng Qinghua
Kleinberg Andrew
Chen Xin
Dong Hanging
Meizhong
Original Assignee
Osi Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osi Pharm Inc filed Critical Osi Pharm Inc
Publication of CL2009000275A1 publication Critical patent/CL2009000275A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Compuestos derivados de furo [3,2.c]piridina y tieno [3,2-c] piridina y sus sales farmacéuticamente aceptables; composición farmacéutica; y su uso en el tratamiento del cáncer, sarcoma, melanoma, retinoblastoma, neuroblastoma, entre otras, que comprende una desregulación de la transmisión mesenquimal epitelial.
CL2009000275A 2008-02-06 2009-02-06 Compuestos derivados de furo [3,2-c]piridina y tieno [3,2-c] piridina; composicion farmaceutica que los comprende; y su uso en el tratamiento del cancer. CL2009000275A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6380008P 2008-02-06 2008-02-06
US11955308P 2008-12-03 2008-12-03

Publications (1)

Publication Number Publication Date
CL2009000275A1 true CL2009000275A1 (es) 2009-06-12

Family

ID=40524808

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2009000275A CL2009000275A1 (es) 2008-02-06 2009-02-06 Compuestos derivados de furo [3,2-c]piridina y tieno [3,2-c] piridina; composicion farmaceutica que los comprende; y su uso en el tratamiento del cancer.

Country Status (19)

Country Link
US (1) US8022206B2 (es)
EP (1) EP2265616B8 (es)
JP (1) JP2011511094A (es)
KR (1) KR20110014971A (es)
CN (1) CN102007127A (es)
AR (1) AR070317A1 (es)
AU (1) AU2009212338A1 (es)
BR (1) BRPI0908050A2 (es)
CA (1) CA2711078A1 (es)
CL (1) CL2009000275A1 (es)
EA (1) EA201070929A1 (es)
ES (1) ES2451024T3 (es)
IL (1) IL206758A0 (es)
MX (1) MX2010008638A (es)
PE (1) PE20091414A1 (es)
TW (1) TW200944201A (es)
UY (1) UY31638A1 (es)
WO (1) WO2009100282A1 (es)
ZA (1) ZA201005554B (es)

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WO2012003338A1 (en) 2010-07-01 2012-01-05 Takeda Pharmaceutical Company Limited COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET
TWI504350B (zh) * 2010-09-01 2015-10-21 Du Pont 殺真菌吡唑及其混合物
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AU2014302365B2 (en) 2013-06-26 2018-11-15 Abbvie Inc. Primary carboxamides as BTK inhibitors
US9907791B2 (en) * 2014-03-14 2018-03-06 University Of Utah Research Foundation Ron inhibitors for use in preventing and treating bone loss
CN103923081B (zh) * 2014-04-14 2017-06-27 武汉光谷人福生物医药有限公司 化合物及其制备方法和应用
ES2764299T3 (es) 2014-12-09 2020-06-02 Inst Nat Sante Rech Med Anticuerpos monoclonales humanos contra AXL
WO2016135041A1 (en) 2015-02-26 2016-09-01 INSERM (Institut National de la Santé et de la Recherche Médicale) Fusion proteins and antibodies comprising thereof for promoting apoptosis
CN106866447A (zh) * 2017-03-30 2017-06-20 成都绿林科技有限公司 一种合成对乙酰基苯甲酰胺的方法
US10957159B2 (en) 2018-04-12 2021-03-23 Aristocrat Technologies Australia Pty Limited Gaming machine and method for displaying a free spin count-up
US11427596B2 (en) * 2019-07-19 2022-08-30 Indian Institute of Technology Indore Metal-free solvent-free synthesis of fused-pyrido heterocycles and biomedical applications

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Also Published As

Publication number Publication date
CN102007127A (zh) 2011-04-06
WO2009100282A1 (en) 2009-08-13
AU2009212338A1 (en) 2009-08-13
CA2711078A1 (en) 2009-08-13
ES2451024T3 (es) 2014-03-26
US8022206B2 (en) 2011-09-20
ZA201005554B (en) 2011-04-28
EA201070929A1 (ru) 2011-04-29
US20090197864A1 (en) 2009-08-06
JP2011511094A (ja) 2011-04-07
BRPI0908050A2 (pt) 2015-08-11
KR20110014971A (ko) 2011-02-14
IL206758A0 (en) 2010-12-30
EP2265616B1 (en) 2013-11-20
EP2265616A1 (en) 2010-12-29
MX2010008638A (es) 2010-08-30
AR070317A1 (es) 2010-03-31
UY31638A1 (es) 2009-09-30
PE20091414A1 (es) 2009-09-23
TW200944201A (en) 2009-11-01
EP2265616B8 (en) 2014-01-08

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