AR090566A1 - Proceso para la produccion de inhibidores de crr - Google Patents
Proceso para la produccion de inhibidores de crrInfo
- Publication number
- AR090566A1 AR090566A1 ARP130101059A ARP130101059A AR090566A1 AR 090566 A1 AR090566 A1 AR 090566A1 AR P130101059 A ARP130101059 A AR P130101059A AR P130101059 A ARP130101059 A AR P130101059A AR 090566 A1 AR090566 A1 AR 090566A1
- Authority
- AR
- Argentina
- Prior art keywords
- formula
- inhibitors
- crr
- production
- alkyl
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- OCQAXYHNMWVLRH-UHFFFAOYSA-N 2,3-dibenzoyl-2,3-dihydroxybutanedioic acid Chemical compound C=1C=CC=CC=1C(=O)C(O)(C(O)=O)C(O)(C(=O)O)C(=O)C1=CC=CC=C1 OCQAXYHNMWVLRH-UHFFFAOYSA-N 0.000 abstract 1
- 102100024167 C-C chemokine receptor type 3 Human genes 0.000 abstract 1
- 101710149862 C-C chemokine receptor type 3 Proteins 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 150000001450 anions Chemical group 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cephalosporin Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12162852 | 2012-04-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR090566A1 true AR090566A1 (es) | 2014-11-19 |
Family
ID=47998462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130101059A AR090566A1 (es) | 2012-04-02 | 2013-03-27 | Proceso para la produccion de inhibidores de crr |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8680280B2 (https=) |
| EP (1) | EP2834229B1 (https=) |
| JP (1) | JP6255550B2 (https=) |
| AR (1) | AR090566A1 (https=) |
| DK (1) | DK2834229T3 (https=) |
| ES (1) | ES2641862T3 (https=) |
| TW (1) | TW201400474A (https=) |
| UY (1) | UY34719A (https=) |
| WO (1) | WO2013149926A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8278302B2 (en) | 2009-04-08 | 2012-10-02 | Boehringer Ingelheim International Gmbh | Substituted piperidines as CCR3 antagonists |
| UA109290C2 (uk) | 2010-10-07 | 2015-08-10 | Спільні кристали і солі інгібіторів ccr3 | |
| AR090566A1 (es) | 2012-04-02 | 2014-11-19 | Boehringer Ingelheim Int | Proceso para la produccion de inhibidores de crr |
| US10213421B2 (en) | 2012-04-04 | 2019-02-26 | Alkahest, Inc. | Pharmaceutical formulations comprising CCR3 antagonists |
| MY199462A (en) | 2017-04-05 | 2023-10-30 | Alkahest Inc | Methods and compositions for treating retina-associated disease using ccr3-inhibitors |
| SG11201909245PA (en) | 2017-04-05 | 2019-11-28 | Alkahest Inc | Methods and compositions for treating aging-associated impairments using ccr3-inhibitors |
| MY198220A (en) | 2018-05-15 | 2023-08-14 | Alkahest Inc | Treatment Of Aging-Associated Disease With Modulators Of Leukotriene A4 Hydrolase |
| AU2021287906B2 (en) | 2020-06-11 | 2025-09-11 | Alkahest Inc. | Methods of improving retina-associated disease outcome using CCR3-inhibitors |
| AU2022376563A1 (en) | 2021-11-01 | 2023-12-07 | Alkahest, Inc. | Benzodioxane modulators of leukotriene a4 hydrolase (lta4h) for prevention and treatment of aging-associated diseases |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7907121L (sv) | 1979-08-27 | 1981-02-28 | Astra Laekemedel Ab | Ftalimidinderivat |
| JP2807577B2 (ja) | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| JPH08134041A (ja) * | 1994-11-10 | 1996-05-28 | Fuji Photo Film Co Ltd | ピラゾールアミド類の製造方法 |
| US6433165B1 (en) | 1998-01-21 | 2002-08-13 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| WO1999038514A1 (en) | 1998-02-02 | 1999-08-05 | Merck & Co., Inc. | Cyclic amine modulators of chemokine receptor activity |
| US6140349A (en) | 1998-02-02 | 2000-10-31 | Merck & Co., Inc. | Cyclic amine modulators of chemokine receptor activity |
| EP1725235B1 (en) | 2004-02-05 | 2009-04-15 | Schering Corporation | Piperidine derivatives useful as ccr3 antagonists |
| JP2006137718A (ja) | 2004-11-12 | 2006-06-01 | Astellas Pharma Inc | インドール若しくはインダゾール誘導体 |
| US8030003B2 (en) | 2004-12-07 | 2011-10-04 | Children's Hospital Medical Center | Diagnosis of eosinophilic esophagitis based on presence of an elevated level of eotaxin-3 |
| DOP2006000051A (es) | 2005-02-24 | 2006-08-31 | Lilly Co Eli | Inhibidores de vegf-r2 y métodos |
| US20090124636A1 (en) | 2006-04-12 | 2009-05-14 | Pfizer Inc. | Chemical compounds |
| GB0701992D0 (en) | 2007-02-02 | 2007-03-14 | 7Tm Pharma As | Grehlin Receptor Modulators |
| US8008092B2 (en) | 2007-10-09 | 2011-08-30 | University Of Kentucky Research Foundation | CCR3 inhibition for ocular angiogenesis and macular degeneration |
| TW201000446A (en) | 2008-05-30 | 2010-01-01 | Astrazeneca Ab | New compounds useful in pain therapy |
| US8278302B2 (en) | 2009-04-08 | 2012-10-02 | Boehringer Ingelheim International Gmbh | Substituted piperidines as CCR3 antagonists |
| UA109290C2 (uk) | 2010-10-07 | 2015-08-10 | Спільні кристали і солі інгібіторів ccr3 | |
| AR090566A1 (es) | 2012-04-02 | 2014-11-19 | Boehringer Ingelheim Int | Proceso para la produccion de inhibidores de crr |
| US20130261153A1 (en) | 2012-04-03 | 2013-10-03 | Boehringer Ingelheim International Gmbh | Use of ccr3-inhibitors |
| US10213421B2 (en) | 2012-04-04 | 2019-02-26 | Alkahest, Inc. | Pharmaceutical formulations comprising CCR3 antagonists |
-
2013
- 2013-03-27 AR ARP130101059A patent/AR090566A1/es unknown
- 2013-03-27 US US13/851,547 patent/US8680280B2/en active Active
- 2013-03-28 JP JP2015503828A patent/JP6255550B2/ja active Active
- 2013-03-28 WO PCT/EP2013/056638 patent/WO2013149926A1/en not_active Ceased
- 2013-03-28 EP EP13712567.0A patent/EP2834229B1/en active Active
- 2013-03-28 ES ES13712567.0T patent/ES2641862T3/es active Active
- 2013-03-28 DK DK13712567.0T patent/DK2834229T3/da active
- 2013-04-01 TW TW102111742A patent/TW201400474A/zh unknown
- 2013-04-02 UY UY0001034719A patent/UY34719A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015516959A (ja) | 2015-06-18 |
| TW201400474A (zh) | 2014-01-01 |
| UY34719A (es) | 2013-10-31 |
| JP6255550B2 (ja) | 2018-01-10 |
| US8680280B2 (en) | 2014-03-25 |
| EP2834229B1 (en) | 2017-08-09 |
| ES2641862T3 (es) | 2017-11-14 |
| WO2013149926A1 (en) | 2013-10-10 |
| US20130261307A1 (en) | 2013-10-03 |
| DK2834229T3 (da) | 2017-11-20 |
| EP2834229A1 (en) | 2015-02-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |