AR073236A1 - Hidrolasas, acidos nucleicos que las codifican y metodos para prepararlas y el uso de las mismas - Google Patents

Hidrolasas, acidos nucleicos que las codifican y metodos para prepararlas y el uso de las mismas

Info

Publication number
AR073236A1
AR073236A1 ARP090103330A ARP090103330A AR073236A1 AR 073236 A1 AR073236 A1 AR 073236A1 AR P090103330 A ARP090103330 A AR P090103330A AR P090103330 A ARP090103330 A AR P090103330A AR 073236 A1 AR073236 A1 AR 073236A1
Authority
AR
Argentina
Prior art keywords
methods
polypeptides
preparing
codify
hydrolases
Prior art date
Application number
ARP090103330A
Other languages
English (en)
Original Assignee
Bunge Oils Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bunge Oils Inc filed Critical Bunge Oils Inc
Publication of AR073236A1 publication Critical patent/AR073236A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D7/00Edible oil or fat compositions containing an aqueous phase, e.g. margarines
    • A23D7/02Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by the production or working-up
    • A23D7/04Working-up
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings, cooking oils
    • A23D9/02Other edible oils or fats, e.g. shortenings, cooking oils characterised by the production or working-up
    • A23D9/04Working-up
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00Refining fats or fatty oils
    • C11B3/003Refining fats or fatty oils by enzymes or microorganisms, living or dead
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11CFATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/02Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils
    • C11C1/04Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by hydrolysis
    • C11C1/045Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by hydrolysis using enzymes or microorganisms, living or dead
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11CFATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/04Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils
    • C11C3/08Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils with fatty acids
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11CFATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/12Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by hydrogenation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6418Fatty acids by hydrolysis of fatty acid esters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6431Linoleic acids [18:2[n-6]]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432Eicosapentaenoic acids [EPA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434Docosahexenoic acids [DHA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6454Glycerides by esterification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6458Glycerides by transesterification, e.g. interesterification, ester interchange, alcoholysis or acidolysis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

HidroIasas, incluyendo lipasas, saturasas, palmitasas y/o estearatasas y polinucleotidos que las codifican y métodos para preparar y usar estos polinucleotidos y polipéptidos. También polipéptidos, por ejemplo, enzimas, que tienen una actividad de hidrolasa, por ejemplo, lipasas, saturasas, palmitasas y/o estearatasas y métodos para preparar aceites de baja saturacion o de bajo contenido de grasas trans, tales como aceites animales o vegetales de baja saturacion o de bajo contenido de grasas trans, por ejemplo, aceites de soja o canola. Además un método para hidrolizar un aceite o una grasa por dichos polipéptidos, un método para la síntesis biocatalítica de un lípido estructurado así como un método de inter-esterificacion para preparar un alimento, nutriente o un aceite.
ARP090103330A 2008-08-29 2009-08-28 Hidrolasas, acidos nucleicos que las codifican y metodos para prepararlas y el uso de las mismas AR073236A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/202,204 US8153391B2 (en) 2008-08-29 2008-08-29 Hydrolases, nucleic acids encoding them and methods for making and using them

Publications (1)

Publication Number Publication Date
AR073236A1 true AR073236A1 (es) 2010-10-20

Family

ID=41664688

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP090103330A AR073236A1 (es) 2008-08-29 2009-08-28 Hidrolasas, acidos nucleicos que las codifican y metodos para prepararlas y el uso de las mismas
ARP160102735A AR105958A2 (es) 2008-08-29 2016-09-07 Métodos para la síntesis biocatalítica de un lípido estructurado, para catalizar una reacción de interesterificación a fin de producir triacilglicéridos, de interesterificación para preparar un alimento, nutriente o un aceite, para producir un 1,3-diacilglicérido (dag) y para hidrolizar un aceite o grasa

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP160102735A AR105958A2 (es) 2008-08-29 2016-09-07 Métodos para la síntesis biocatalítica de un lípido estructurado, para catalizar una reacción de interesterificación a fin de producir triacilglicéridos, de interesterificación para preparar un alimento, nutriente o un aceite, para producir un 1,3-diacilglicérido (dag) y para hidrolizar un aceite o grasa

Country Status (13)

Country Link
US (6) US8153391B2 (es)
EP (1) EP2329032B1 (es)
CN (1) CN102325891B (es)
AR (2) AR073236A1 (es)
BR (1) BRPI0917220B1 (es)
CA (1) CA2735265C (es)
ES (1) ES2484919T3 (es)
MX (1) MX2011002226A (es)
MY (1) MY162662A (es)
PL (1) PL2329032T3 (es)
RU (1) RU2525675C2 (es)
UA (1) UA101214C2 (es)
WO (1) WO2010024924A2 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10314594B2 (en) 2012-12-14 2019-06-11 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10813630B2 (en) 2011-08-09 2020-10-27 Corquest Medical, Inc. Closure system for atrial wall
US10307167B2 (en) 2012-12-14 2019-06-04 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
CA2875830C (en) 2012-06-14 2020-08-04 Bunge Global Innovation Llc Process for production of low saturate oils
US20140142689A1 (en) 2012-11-21 2014-05-22 Didier De Canniere Device and method of treating heart valve malfunction
US9566443B2 (en) 2013-11-26 2017-02-14 Corquest Medical, Inc. System for treating heart valve malfunction including mitral regurgitation
CN106591386A (zh) * 2014-07-07 2017-04-26 嘉必优生物技术(武汉)股份有限公司 含有2‑棕榈酸甘油酯的组合物的制备方法
US10842626B2 (en) 2014-12-09 2020-11-24 Didier De Canniere Intracardiac device to correct mitral regurgitation
US20170049121A1 (en) 2015-08-20 2017-02-23 Bunge Oils, Inc. High stearic high oleic shortening compositions and methods of making and using the same
CN109929820B (zh) * 2017-12-19 2022-10-11 丰益(上海)生物技术研发中心有限公司 新型的甘油单-二酰酯脂肪酶
CN108034647B (zh) * 2018-01-31 2020-08-04 江南大学 一种饱和脂肪酸特异性脂肪酶突变体及其应用
JP7359539B2 (ja) * 2018-03-29 2023-10-11 日清オイリオグループ株式会社 油脂組成物、加熱調理用油脂組成物、加熱調理用油脂組成物の製造方法、並びに、油脂組成物における酸価上昇及び色調上昇の抑制方法
WO2019213754A1 (en) * 2018-05-07 2019-11-14 Gates Ian D Method of enzymatic biotransformation of petroleum hydrocarbon
CN112534050A (zh) * 2018-05-18 2021-03-19 帝斯曼知识产权资产管理有限公司 突变体脂肪酶及其用途
US20220046953A1 (en) * 2018-12-13 2022-02-17 Cargill, Incorporated Modified Triglyceride Including Omega-3 Fatty Acid Residue
EP4211256A1 (en) 2020-09-07 2023-07-19 Boehringer Ingelheim International Gmbh Method for detecting contaminating lipase activity
WO2023170139A1 (en) 2022-03-09 2023-09-14 Boehringer Ingelheim International Gmbh Method for detecting contaminating carboxylesterase activity
WO2024033465A1 (en) * 2022-08-10 2024-02-15 Boehringer Ingelheim International Gmbh Artificial mirnas targeting multiple hydrolases

Family Cites Families (138)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3949105A (en) 1974-03-25 1976-04-06 Lever Brothers Company Margarine fat
US4261868A (en) 1979-08-08 1981-04-14 Lever Brothers Company Stabilized enzymatic liquid detergent composition containing a polyalkanolamine and a boron compound
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US4404128A (en) 1981-05-29 1983-09-13 The Procter & Gamble Company Enzyme detergent composition
IE54838B1 (en) 1982-04-30 1990-02-28 Unilever Plc Improvements in and relating to interesterification of triglycerides of fatty acids
DK402583D0 (da) 1983-09-05 1983-09-05 Novo Industri As Fremgangsmade til fremstilling af et immobiliseret lipasepraeparat og anvendelse deraf
US4707364A (en) 1984-01-27 1987-11-17 Miles Laboratories, Inc. Composition for accelerating cheese aging
US5204015A (en) 1984-05-29 1993-04-20 Genencor International, Inc. Subtilisin mutants
US5087571A (en) 1984-06-22 1992-02-11 President And Fellows Of Harvard College Method for providing a cell culture from a transgenic non-human mammal
US5691181A (en) 1984-08-21 1997-11-25 Celltech Limited DNA encoding lipase from human gastric mucosal tissue
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
DE3546806C2 (es) 1985-03-30 1991-03-28 Marc Genf/Geneve Ch Ballivet
US4752483A (en) 1986-05-30 1988-06-21 Campbell Soup Company Method for producing a highly flavored cheese ingredient
US4962028A (en) 1986-07-09 1990-10-09 Dna Plant Technology Corporation Plant promotors
CH671155A5 (es) 1986-08-18 1989-08-15 Clinical Technologies Ass
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US5015580A (en) 1987-07-29 1991-05-14 Agracetus Particle-mediated transformation of soybean plants and lines
US5573933A (en) 1987-04-14 1996-11-12 Luminis Pty, Ltd. Transgenic pigs
US4897268A (en) 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
US4944944A (en) 1987-11-19 1990-07-31 Oklahoma Medical Research Foundation Dietary compositions and methods using bile salt-activated lipase
US5700637A (en) 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
US6054270A (en) 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
US5000975A (en) 1988-12-29 1991-03-19 American Home Products Corporation Randomized palm oil fat composition for infant formulas
US5217879A (en) 1989-01-12 1993-06-08 Washington University Infectious Sindbis virus vectors
US5069810A (en) 1989-03-16 1991-12-03 Olin Corporation Cleaning composition comprising microbial lipase SD2 and sodium dodecylbenzene sulfonate
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5527681A (en) 1989-06-07 1996-06-18 Affymax Technologies N.V. Immobilized molecular synthesis of systematically substituted compounds
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5288619A (en) 1989-12-18 1994-02-22 Kraft General Foods, Inc. Enzymatic method for preparing transesterified oils
DE69133372T2 (de) 1990-06-15 2005-02-24 Scios Inc., Sunnyvale Transgenes, nicht-menschliches säugetier das die amyloidbildende pathologie der alzheimerschen krankheit zeigt
ATE191931T1 (de) 1990-11-23 2000-05-15 Plant Genetic Systems Nv Verfahren zur transformation monokotyler pflanzen
CA2098824A1 (en) 1990-12-20 1992-06-21 William D. Huse Optimization of binding proteins
US6110700A (en) 1991-03-11 2000-08-29 The General Hospital Corporation PRAD1 cyclin and its cDNA
DE4115938A1 (de) 1991-05-16 1992-11-19 Metallgesellschaft Ag Enzymatisches verfahren zur verminderung des gehaltes an phosphorhaltigen bestandteilen in pflanzlichen und tierischen oelen
US5922854A (en) 1991-06-14 1999-07-13 Kumar; Ramesh Purifying Human Hemogloblin from transgenic pig red cells and plasmids containing pig globin nucleic acids
CA2075135A1 (en) 1991-08-02 1993-02-03 David E. Ellis Particle-mediated transformation of gymnosperms
US5632957A (en) 1993-11-01 1997-05-27 Nanogen Molecular biological diagnostic systems including electrodes
JPH05236997A (ja) 1992-02-28 1993-09-17 Hitachi Ltd ポリヌクレオチド捕捉用チップ
US5902617A (en) 1992-05-19 1999-05-11 Pabst; Patrea L. Enzyme supplemented baby formula
US5445955A (en) 1992-05-25 1995-08-29 The Nisshin Oil Mills, Ltd. Immobilization of lipase on a polymer carrier containing epoxy and tertiary amino groups
EP0571982A1 (en) 1992-05-27 1993-12-01 Showa Denko Kabushiki Kaisha Alkaline lipase, method for producing the same, microorganism producing the same and detergent composition containing alkaline lipase
WO1994012014A1 (en) 1992-11-20 1994-06-09 Agracetus, Inc. Transgenic cotton plants producing heterologous bioplastic
EP0698090B1 (en) 1993-05-20 1997-11-26 Loders Croklaan B.V. Process for preparing immobilized lipases
JP2859520B2 (ja) 1993-08-30 1999-02-17 ノボ ノルディスク アクティーゼルスカブ リパーゼ及びそれを生産する微生物及びリパーゼ製造方法及びリパーゼ含有洗剤組成物
JPH08509871A (ja) 1993-09-30 1996-10-22 アグラシータス インコーポレイテッド 異種ペルオキシダーゼを生産するトランスジェニック綿植物
US6045996A (en) 1993-10-26 2000-04-04 Affymetrix, Inc. Hybridization assays on oligonucleotide arrays
US5965452A (en) 1996-07-09 1999-10-12 Nanogen, Inc. Multiplexed active biologic array
US6468742B2 (en) 1993-11-01 2002-10-22 Nanogen, Inc. Methods for determination of single nucleic acid polymorphisms using bioelectronic microchip
US5834252A (en) 1995-04-18 1998-11-10 Glaxo Group Limited End-complementary polymerase reaction
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5639940A (en) 1994-03-03 1997-06-17 Pharmaceutical Proteins Ltd. Production of fibrinogen in transgenic animals
EP0749492A1 (en) 1994-03-09 1996-12-27 Abbott Laboratories Humanized milk
JPH09509848A (ja) 1994-03-09 1997-10-07 アボツト・ラボラトリーズ オリゴ糖及び複合糖質を産生するトランスジェニック動物
AU2067795A (en) 1994-03-29 1995-10-17 Novo Nordisk A/S Alkaline bacillus amylase
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US5750870A (en) 1994-06-17 1998-05-12 Agritope, Inc. Plant genetic transformation methods and transgenic plants
US5959171A (en) 1994-08-17 1999-09-28 Pharming B.V. Method for the production of biologically active polypeptides in a mammal's
US6211428B1 (en) 1994-09-01 2001-04-03 Merck & Co., Inc. Transgenic mouse expressing a familial form of human amyloid precursor protein
US6111166A (en) 1994-09-19 2000-08-29 Medarex, Incorporated Transgenic mice expressing human Fcα and β receptors
US5795737A (en) 1994-09-19 1998-08-18 The General Hospital Corporation High level expression of proteins
US5880327A (en) 1994-09-21 1999-03-09 American National Red Cross Transgenic mammals expressing human coagulation factor VIII
US5556752A (en) 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
EP0713917A1 (fr) * 1994-11-28 1996-05-29 Societe Des Produits Nestle S.A. Procédé d'hydrolyse des triglycérides d'acides gras polyinsaturés
US6187992B1 (en) 1994-12-05 2001-02-13 Merck & Co., Inc. Transgenic mouse having a disrupted amyloid precursor protein gene
US5830645A (en) 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US5633440A (en) 1994-12-20 1997-05-27 Dna Plant Technology Corporation P119 promoters and their uses
US6093562A (en) 1996-02-05 2000-07-25 Novo Nordisk A/S Amylase variants
US5959098A (en) 1996-04-17 1999-09-28 Affymetrix, Inc. Substrate preparation process
US6313081B1 (en) 1995-04-28 2001-11-06 Henkel Kommanditgesellschaft Auf Aktien (Kgaa) Detergents comprising cellulases
US5552317A (en) 1995-05-26 1996-09-03 Industrial Technology Research Institute Method for preparing optically active homophenylalanine and esters thereof using lipase from wheat germ or Candida lipolytica
BR9608197A (pt) * 1995-05-31 1998-07-21 Henkel Corp Processo contínuo para a produçao de ácidos carboxílicos e glicerina a partir de um glicerídeo
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5958672A (en) 1995-07-18 1999-09-28 Diversa Corporation Protein activity screening of clones having DNA from uncultivated microorganisms
US6740506B2 (en) 1995-12-07 2004-05-25 Diversa Corporation End selection in directed evolution
US6537776B1 (en) 1999-06-14 2003-03-25 Diversa Corporation Synthetic ligation reassembly in directed evolution
US5965408A (en) 1996-07-09 1999-10-12 Diversa Corporation Method of DNA reassembly by interrupting synthesis
US6358709B1 (en) 1995-12-07 2002-03-19 Diversa Corporation End selection in directed evolution
US6361974B1 (en) 1995-12-07 2002-03-26 Diversa Corporation Exonuclease-mediated nucleic acid reassembly in directed evolution
US5939250A (en) 1995-12-07 1999-08-17 Diversa Corporation Production of enzymes having desired activities by mutagenesis
US6171820B1 (en) 1995-12-07 2001-01-09 Diversa Corporation Saturation mutagenesis in directed evolution
US5830696A (en) 1996-12-05 1998-11-03 Diversa Corporation Directed evolution of thermophilic enzymes
US6238884B1 (en) 1995-12-07 2001-05-29 Diversa Corporation End selection in directed evolution
US6022963A (en) 1995-12-15 2000-02-08 Affymetrix, Inc. Synthesis of oligonucleotide arrays using photocleavable protecting groups
US6013440A (en) 1996-03-11 2000-01-11 Affymetrix, Inc. Nucleic acid affinity columns
US6096548A (en) 1996-03-25 2000-08-01 Maxygen, Inc. Method for directing evolution of a virus
US6197070B1 (en) 1996-05-15 2001-03-06 The Procter & Gamble Company Detergent compositions comprising alpha combination of α-amylases for malodor stripping
CA2261571A1 (en) 1996-07-30 1998-02-05 The Procter & Gamble Company Detergent composition comprising two cellulase components, with and without a cellulose-binding domain
US6326341B1 (en) 1996-09-11 2001-12-04 The Procter & Gamble Company Low foaming automatic dishwashing compositions
US5834259A (en) 1996-10-28 1998-11-10 Monsanto Company Process and composition for preparing D-aspartic acid
CA2275707A1 (en) 1996-12-19 1998-06-25 Unilever Plc Immobilized enzyme and its use for the processing of triglyceride oils
US6069122A (en) 1997-06-16 2000-05-30 The Procter & Gamble Company Dishwashing detergent compositions containing organic diamines for improved grease cleaning, sudsing, low temperature stability and dissolution
DE69835360T2 (de) 1997-01-17 2007-08-16 Maxygen, Inc., Redwood City EVOLUTION Prokaryotischer GANZER ZELLEN DURCH REKURSIVE SEQUENZREKOMBINATION
US6326204B1 (en) 1997-01-17 2001-12-04 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
DE19703364A1 (de) 1997-01-30 1998-08-06 Henkel Ecolab Gmbh & Co Ohg Pastenförmiges Wasch- und Reinigungsmittel
US6153410A (en) 1997-03-25 2000-11-28 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
US6826296B2 (en) 1997-07-25 2004-11-30 Affymetrix, Inc. Method and system for providing a probe array chip design database
CN100367023C (zh) 1997-09-11 2008-02-06 生物风险公司 制备高密度阵列的方法
US6465178B2 (en) 1997-09-30 2002-10-15 Surmodics, Inc. Target molecule attachment to surfaces
DE69842027D1 (de) 1997-10-30 2011-01-13 Novozymes As Mutanten der alpha-amylase
WO1999024550A1 (en) 1997-11-10 1999-05-20 The Procter & Gamble Company Process for preparing a detergent tablet
DE69828574T2 (de) 1997-11-14 2005-10-06 Sankyo Co., Ltd. Transgenes Tier als Modell für Allergie und seine Verwendung
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
US6156952A (en) 1998-04-09 2000-12-05 Constituent Institution Of The University Of Maryland System HIV transgenic animals and uses therefor
AU3408199A (en) 1998-05-01 1999-11-23 Novo Nordisk A/S Enhancers such as n-hydroxyacetanilide
US6048695A (en) 1998-05-04 2000-04-11 Baylor College Of Medicine Chemically modified nucleic acids and methods for coupling nucleic acids to solid support
DE19824705A1 (de) 1998-06-03 1999-12-09 Henkel Kgaa Amylase und Protease enthaltende Wasch- und Reinigungsmittel
JP4335995B2 (ja) 1998-07-22 2009-09-30 昭 神谷 環境保全型粒状洗浄用組成物
GB2340755B (en) 1998-08-24 2002-09-25 Cannon Rubber Ltd Breast pump insert
US6277628B1 (en) 1998-10-02 2001-08-21 Incyte Genomics, Inc. Linear microarrays
US6277489B1 (en) 1998-12-04 2001-08-21 The Regents Of The University Of California Support for high performance affinity chromatography and other uses
US6376246B1 (en) 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6436675B1 (en) 1999-09-28 2002-08-20 Maxygen, Inc. Use of codon-varied oligonucleotide synthesis for synthetic shuffling
US6368861B1 (en) 1999-01-19 2002-04-09 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6399121B1 (en) 1999-03-16 2002-06-04 Novozymes A/S Process for producing cheese
US6511824B1 (en) 1999-03-17 2003-01-28 Exelixis, Inc. Nucleic acids and polypeptides of invertebrate TWIK channels and methods of use
US6309871B1 (en) 1999-03-31 2001-10-30 Novozymes A/S Polypeptides having alkaline α-amylase activity
US6221653B1 (en) 1999-04-27 2001-04-24 Agilent Technologies, Inc. Method of performing array-based hybridization assays using thermal inkjet deposition of sample fluids
US6653151B2 (en) 1999-07-30 2003-11-25 Large Scale Proteomics Corporation Dry deposition of materials for microarrays using matrix displacement
US6337187B1 (en) 1999-11-05 2002-01-08 Millennium Pharmaceuticals, Inc. 18891, a novel human lipase
US20010008765A1 (en) 1999-12-06 2001-07-19 Fuji Photo Film Co., Ltd. DNA chip and reactive solid carrier
US6531644B1 (en) 2000-01-14 2003-03-11 Exelixis, Inc. Methods for identifying anti-cancer drug targets
AU1166502A (en) 2000-10-12 2002-04-22 Exelixis Inc Human ect2 and methods of use
US6309872B1 (en) 2000-11-01 2001-10-30 Novozymes Biotech, Inc Polypeptides having glucoamylase activity and nucleic acids encoding same
MXPA04007886A (es) 2002-02-13 2004-10-15 Dow Global Technologies Inc Sobre-expresion de genes de extremozimo en pseudomonadas y bacterias estrechamente relacionadas.
FI115842B (fi) * 2002-03-27 2005-07-29 Valio Oy Menetelmä konjugoidun linolihapon valmistamiseksi
WO2005032496A2 (en) * 2003-03-07 2005-04-14 Diversa Corporation Hydrolases, nucleic acids encoding them and mehods for making and using them
KR101237651B1 (ko) 2003-11-19 2013-02-27 다우 글로벌 테크놀로지스 엘엘씨 개선된 단백질 발현 시스템
EP1805302B1 (en) * 2004-10-08 2012-08-15 Novozymes A/S Hydrolysis of ester bonds with lipase
DE102005012113A1 (de) * 2004-12-27 2006-07-27 BSH Bosch und Siemens Hausgeräte GmbH Geschirrspülmaschine mit einer Trocknungsvorrichtung
CA2601472A1 (en) 2005-03-08 2006-09-14 Verenium Corporation Hydrolases, nucleic acids encoding them and methods for improving paper strength
CN101495644B (zh) 2006-05-30 2012-11-07 陶氏环球技术有限责任公司 密码子优化方法
UA97127C2 (uk) 2006-12-06 2012-01-10 Бандж Ойлз, Инк. Спосіб безперервної ферментативної обробки композиції, що містить ліпід, та система для його здійснення

Also Published As

Publication number Publication date
WO2010024924A2 (en) 2010-03-04
US20100055234A1 (en) 2010-03-04
US20110287136A1 (en) 2011-11-24
MY162662A (en) 2017-06-30
US8541191B2 (en) 2013-09-24
US8153391B2 (en) 2012-04-10
CA2735265A1 (en) 2010-03-04
EP2329032A2 (en) 2011-06-08
US20110287496A1 (en) 2011-11-24
US8313918B2 (en) 2012-11-20
UA101214C2 (ru) 2013-03-11
BRPI0917220A2 (pt) 2015-08-11
BRPI0917220B1 (pt) 2018-11-21
US8227215B2 (en) 2012-07-24
ES2484919T3 (es) 2014-08-12
CN102325891B (zh) 2015-01-07
US20110287495A1 (en) 2011-11-24
US8349578B2 (en) 2013-01-08
US20110281312A1 (en) 2011-11-17
EP2329032B1 (en) 2014-04-30
PL2329032T3 (pl) 2014-09-30
MX2011002226A (es) 2011-04-05
RU2011111747A (ru) 2012-10-10
AR105958A2 (es) 2017-11-29
WO2010024924A3 (en) 2010-04-29
CA2735265C (en) 2019-04-23
US20120276618A1 (en) 2012-11-01
CN102325891A (zh) 2012-01-18
RU2525675C2 (ru) 2014-08-20
US8420342B2 (en) 2013-04-16

Similar Documents

Publication Publication Date Title
AR073236A1 (es) Hidrolasas, acidos nucleicos que las codifican y metodos para prepararlas y el uso de las mismas
EA201170388A1 (ru) Гидролазы, кодирующие их нуклеиновые кислоты и способы их получения и применения
ECSP099800A (es) Producción de aceite en microorganismos
CL2017000049A1 (es) Procesos para producir productos industriales de lípidos vegetales
MY195138A (en) Microorganisms and Methods for Production of Specific Length Fatty Alcohols and Related Compounds
AR078583A1 (es) Fosfolipasas, acidos nucleicos que las codifican y metodos para prepararlas y usarlas
CR20150579A (es) Composiciones y métodos para producir cetosis elevada y sostenida
CO6400156A2 (es) Producciòn de aceites específicos en microorganismos heterotrofos
UA108850C2 (uk) Екстракт цілісного насіння видів moringa та його застосування у косметичній та/або дерматологічній композиції
CL2011001162A1 (es) Aceites obtienidos de celulas recombinantes que comprenden polinucleotidos codificantes para enzimas con actividad desaturasa y elongasa, metodo de produccion de dichos aceites, y productos directamente derivados de los mismos.
CL2014000156A1 (es) Metodo para producir una biomasa de un microorganismo que tiene acidos grasos y una concentración de epa; aceite extraído de dicha biomasa.
CL2012002897A1 (es) Metodo que comprende procesar biomasa microbiana interrumpida no tratada que tiene una composicion de aceite y fraccionar el extracto obtenido para obtener una composicion lipidica de al menos un acido graso poliinsaturado.
AR078858A1 (es) Proteinas encapsulantes de lipidos neutros modificadas y sus usos
MX2012000654A (es) Obtencion de acidos grasos a partir de larvas de insectos.
CL2011001462A1 (es) Yarrowia sp. transgenica util en la fermentacion de acidos grasos poliinsaturados que comprende un polipeptido con actividad malonil-coa sintetasa; y metodo para reducir la produccion de malonatos como subproducto de la fermetacion basado en el uso de dicha yarrowia.
AR069443A1 (es) Purificacion de materiales grasos tal como aceite
AR058650A1 (es) Procedimiento para preparar acido araquidonico y/o acido eicosapentaenoico en plantas utiles transgenicas
EA201290903A1 (ru) Способ рафинирования растительного масла и рафинированное растительное масло, полученное указанным способом
EA201400690A1 (ru) Пищевые продукты на жировой основе
EP4163354A3 (en) Polypeptides having phospholipase c activity and polynucleotides encoding same
PH12014501720A1 (en) Enzymatic process for fat and oil hydrolysis
BRPI0913122A2 (pt) método para obtenção de óleo enriquecido e óleo enriquecido resultante
AR046492A1 (es) Metodo para la produccion de acidos grasos con un bajo contenido de acidos grasos trans
CL2019001708A1 (es) Métodos para producir biomasa rica en dha, ácido palmítico y proteínas con un microorganismo eucariota.
AR083061A1 (es) Procedimiento para remover componentes que contienen fosforo y esterilglicosidos de aceite crudo o aceite previamente desmucilaginado de origen vegetal o animal

Legal Events

Date Code Title Description
FG Grant, registration