AR061152A1 - Vacuna recombinante contra virus de la lengua azul - Google Patents

Vacuna recombinante contra virus de la lengua azul

Info

Publication number
AR061152A1
AR061152A1 ARP070102369A ARP070102369A AR061152A1 AR 061152 A1 AR061152 A1 AR 061152A1 AR P070102369 A ARP070102369 A AR P070102369A AR P070102369 A ARP070102369 A AR P070102369A AR 061152 A1 AR061152 A1 AR 061152A1
Authority
AR
Argentina
Prior art keywords
btv
composition
language
blue
vector
Prior art date
Application number
ARP070102369A
Other languages
English (en)
Inventor
Jean-Christophe Audonnet
Kemal Karaca
Jiansheng Yao
Nigel James Maclanchlan
Original Assignee
Merial Ltd
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd, Univ California filed Critical Merial Ltd
Publication of AR061152A1 publication Critical patent/AR061152A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12111—Orbivirus, e.g. bluetongue virus
    • C12N2720/12122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12111—Orbivirus, e.g. bluetongue virus
    • C12N2720/12134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)

Abstract

La presente se refiere a una composicion inmunogénica o vacuna para inducir una respuesta inmune o respuesta inmunoprotectora contra Orbivirus, más específicamente el virus de lengua azul (BTV) en un animal susceptible de la infeccion causada por el BTV. La composicion puede incluir un vehículo o excipiente farmacéutica o veterinariamente aceptable, y un vector. El vector puede contener una/s molécula(s) de ácidos nucleicos heterologa(s), expresa in vivo en el animal el antígeno, inmunogeno o epítopo de BTV, por ejemplo, VP2 BTV, VP5 BTV, VP2 y VP5 BTV, VP3 BTV, VP7 BTV, VP2 y VP5 y VP3 BTV, VP2 y VP5 y VP7 BTV. La composicion puede contener un adyuvante, como ser un carbomero. También se contemplan los métodos para preparar y utilizar dicha composicion, incluidos los regímenes de primera dosis-refuerzo e incluido el diagnostico diferencial. Un kit para llevar a cabo el método, de las distintas reivindicaciones.
ARP070102369A 2006-06-01 2007-06-01 Vacuna recombinante contra virus de la lengua azul AR061152A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/444,698 US7862821B2 (en) 2006-06-01 2006-06-01 Recombinant vaccine against bluetongue virus

Publications (1)

Publication Number Publication Date
AR061152A1 true AR061152A1 (es) 2008-08-06

Family

ID=38790493

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070102369A AR061152A1 (es) 2006-06-01 2007-06-01 Vacuna recombinante contra virus de la lengua azul

Country Status (17)

Country Link
US (1) US7862821B2 (es)
EP (2) EP2029622A2 (es)
CN (2) CN103143034A (es)
AR (1) AR061152A1 (es)
AU (1) AU2007293474C9 (es)
BR (1) BRPI0712191A2 (es)
CA (1) CA2653696C (es)
ES (1) ES2623138T3 (es)
HK (1) HK1200180A1 (es)
IL (1) IL195641A (es)
MA (1) MA30569B1 (es)
NZ (1) NZ573435A (es)
RU (1) RU2446823C2 (es)
TW (1) TWI399213B (es)
UY (1) UY30385A1 (es)
WO (1) WO2008030282A2 (es)
ZA (1) ZA200810826B (es)

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CN104619720A (zh) * 2012-08-29 2015-05-13 英特维特国际股份有限公司 标记疫苗
CN103305473B (zh) * 2013-06-18 2015-01-07 中国农业科学院哈尔滨兽医研究所 抗蓝舌病病毒血清1型vp2蛋白的单克隆抗体btv1-4b6及其识别的b细胞表位多肽与应用
CN103305472A (zh) * 2013-06-18 2013-09-18 中国农业科学院哈尔滨兽医研究所 抗蓝舌病病毒血清1型vp2蛋白的单克隆抗体btv1-3e8及其识别的b细胞表位多肽与应用
CN104258138A (zh) * 2014-09-28 2015-01-07 山东新希望六和集团有限公司 一种用于治疗牛蓝舌病的药物组合物及其制备方法
AU2019239552A1 (en) 2018-03-19 2020-09-10 Boehringer Ingelheim Vetmedica Gmbh EHV insertion site UL43
CN110551634A (zh) * 2019-09-04 2019-12-10 中国农业科学院兰州兽医研究所 一种山羊支原体山羊肺炎亚种分离培养方法
CN110551653A (zh) * 2019-09-04 2019-12-10 中国农业科学院兰州兽医研究所 一种无血清制备牛支原体抗原的方法
CN113308441B (zh) * 2021-06-02 2022-05-10 华中农业大学 一株猫疱疹病毒i型病毒株及其应用

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RU2008152064A (ru) 2010-07-20
EP2029622A2 (en) 2009-03-04
NZ573435A (en) 2011-09-30
CN103143034A (zh) 2013-06-12
EP2816057B1 (en) 2017-02-01
IL195641A (en) 2013-12-31
AU2007293474C1 (en) 2014-06-05
WO2008030282A3 (en) 2009-12-17
BRPI0712191A2 (pt) 2012-03-06
CN101754975A (zh) 2010-06-23
IL195641A0 (en) 2011-08-01
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AU2007293474B2 (en) 2012-07-19
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CA2653696C (en) 2017-10-24
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US20070280960A1 (en) 2007-12-06
CN101754975B (zh) 2013-01-02
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US7862821B2 (en) 2011-01-04

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