AR061021A1 - Derivados de ciclopropilamidas y composiciones antimicrobianas - Google Patents

Derivados de ciclopropilamidas y composiciones antimicrobianas

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Publication number
AR061021A1
AR061021A1 ARP070102155A ARP070102155A AR061021A1 AR 061021 A1 AR061021 A1 AR 061021A1 AR P070102155 A ARP070102155 A AR P070102155A AR P070102155 A ARP070102155 A AR P070102155A AR 061021 A1 AR061021 A1 AR 061021A1
Authority
AR
Argentina
Prior art keywords
substituted
alkyl
independently
substituents
hydrogen
Prior art date
Application number
ARP070102155A
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English (en)
Original Assignee
Syngenta Participations Ag
Syngenta Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag, Syngenta Ltd filed Critical Syngenta Participations Ag
Publication of AR061021A1 publication Critical patent/AR061021A1/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/24Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/64Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/66Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/041,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06Six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D411/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

Reivindicacion 1: Un compuesto de formula 1 donde X es oxigeno o azufre; A es un anillo heterocíclico de 5 o 6 miembros que contiene de uno a tres heteroátomos, cada uno seleccionado independientemente de oxígeno, nitrogeno y azufre, o un anillo fenilo; donde el anillo heterocíclico o el fenilo están sustituidos por los grupos R6, R7 y R8; R6, R7 y R8 son cada uno, independientemente, hidrogeno, halogeno, ciano, nitro, alquilo C1-4, halogenoalquilo C1-4, halogenoalcoxi C1-4, alcoxi C1-4- alquilo C1-4 o halogenoalcoxi C1-4-alquilo C1-4, con la condicion de que al menos uno de R6, R7 y R8 no sea hidrogeno; R1, R2, R3 y R4 independientemente uno del otro representan halogeno, ciano, nitro, alquilo C1-6, el cual no está sustituido o está sustituido con uno o varios sustituyentes Ra, cicloalquilo C3-6, el cual no está sustituido o está sustituido con uno o varios sustituyentes Ra, alquenilo C2-6, el cual no está sustituido o está sustituido con uno o varios sustituyentes Ra o alquinilo C2-6, el cual no está sustituido o está sustituido con uno o varios sustituyentes Ra; cada Ra independientemente uno del otro representan halogeno, ciano, nitro, alcoxi C1-6, halogenoalcoxi C1-6, cicloalquilo C3-6, alquiltio C1-6, halogenoalquiltio C1-6 o -C(Rb)=N(ORc); Rb es hidrogeno o alquilo C1-6; Rc es alquilo C1-6; n es 0, 1, 2, 3 o 4; R5 es hidrogeno, alquilo C1-4, CH2CH=CHR5a, CH2C:::CR5b o COR5c; R5a y R5b son cada uno, independientemente, hidrogeno, alquilo C1-6, halogenoalquilo C1-6, alquenilo C2-6, alquinilo C2-6, cicloalquilo C3-7, COOalquilo C1-4, COOalquenilo C3-6, COOalquinilo C3-6 o CN; R5c es hidrogeno, alquilo C1-6, halogenoalquilo C1-6, alcoxi C1-6-alquilo C1-6, halogenoalcoxi C1-6-alquilo C1-6, alquiltio C1-6, halogenoalquiltio C1-6, alcoxi C1-6, halogenoalcoxi C1-6, alqueniloxi C3-6, halogenoalqueniloxi C3-6, alquiniloxi C3-6 o halogenoalquiniloxi C3-6; B es un grupo fenilo, naftilo o quinolinilo, el cual está sustituido con uno o varios sustituyentes Rg; cada sustituyente Rg independientemente uno del otro representa halogeno, ciano, nitro, -C(Rd)=N(ORe) o un grupo -L-Rf; cada Rd es, independientemente uno del otro, hidrogeno o alquilo C1-6; cada Re es, independientemente uno del otro, alquilo C1-6; cada L es, independientemente uno del otro, un enlace, -O- o -S-; cada Rf es, independientemente uno del otro, alquilo C1-6, el cual no está sustituido o está sustituido con uno o varios sustituyentes Rh, cicIoalquilo C3-6, el cual no está sustituido o está sustituido con uno o varios sustituyentes Rh, bicicloalquilo C6-14, el cual no está sustituido o está sustituido con uno o varios sustituyentes Rh, alquenilo C2-6, el cual no está sustituido o está sustituido con uno o varios sustituyentes Rh, alquinilo C2-6, el cual no está sustituido o está sustituido con uno o varios sustituyentes Rh, fenilo, el cual no está sustituido o está sustituido con uno o varios sustituyente Rh o heteroarilo, el cual no está sustituido o está sustituido con uno o varios sustituyentes Rh; cada Rh es, independientemente uno del otro, halogeno, ciano, nitro, alcoxi C1-6, halogenoalcoxi C1-6, alquiltio C1-6, halogenoalquiltio C1-6, alqueniloxi C3-6, alquiniloxi C3-6 o -C(Rj)=N(ORk); cada Rj es, independientemente uno del otro, hidrogeno o alquilo C1-6; cada Rk es, independientemente uno del otro, alquilo C1-6 y tautomeros, isomeros y enantiomeros de estos compuestos.
ARP070102155A 2006-05-18 2007-05-18 Derivados de ciclopropilamidas y composiciones antimicrobianas AR061021A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06010224 2006-05-18

Publications (1)

Publication Number Publication Date
AR061021A1 true AR061021A1 (es) 2008-07-30

Family

ID=38474462

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070102155A AR061021A1 (es) 2006-05-18 2007-05-18 Derivados de ciclopropilamidas y composiciones antimicrobianas

Country Status (15)

Country Link
US (1) US8618023B2 (es)
EP (1) EP2018367B1 (es)
JP (1) JP5155303B2 (es)
KR (1) KR101380139B1 (es)
CN (1) CN101466671B (es)
AR (1) AR061021A1 (es)
AT (1) ATE449068T1 (es)
BR (1) BRPI0712027B1 (es)
CA (1) CA2650795A1 (es)
DE (1) DE602007003343D1 (es)
ES (1) ES2335319T3 (es)
GT (1) GT200700041A (es)
MX (1) MX2008014534A (es)
TW (1) TWI388547B (es)
WO (1) WO2007134799A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010003155A (es) * 2007-10-04 2010-04-01 Hoffmann La Roche Derivados de ciclopropil aril amida y uso de los mismos.
WO2010084160A1 (en) 2009-01-21 2010-07-29 Oryzon Genomics S.A. Phenylcyclopropylamine derivatives and their medical use
BRPI1006006B1 (pt) * 2009-02-17 2018-05-22 Bayer Intellectual Property Gmbh Compostos, composição fungicida e método para o controle de fungos fitopatogênicos de culturas
MX338041B (es) 2009-09-25 2016-03-30 Oryzon Genomics Sa Inhibidores de demetilasa-1 especificos de lisina y su uso.
EP2486002B1 (en) 2009-10-09 2019-03-27 Oryzon Genomics, S.A. Substituted heteroaryl- and aryl- cyclopropylamine acetamides and their use
US8357635B2 (en) 2009-10-16 2013-01-22 Syngenta Crop Protection Llc Microbiocides
US9186337B2 (en) 2010-02-24 2015-11-17 Oryzon Genomics S.A. Lysine demethylase inhibitors for diseases and disorders associated with Hepadnaviridae
US9616058B2 (en) 2010-02-24 2017-04-11 Oryzon Genomics, S.A. Potent selective LSD1 inhibitors and dual LSD1/MAO-B inhibitors for antiviral use
KR101794020B1 (ko) 2010-04-19 2017-11-06 오리존 지노믹스 에스.에이. 라이신 특이적 디메틸라아제-1 억제제 및 이의 용도
MX2012013897A (es) 2010-06-03 2012-12-17 Bayer Cropscience Ag N[(het)ariletil)]pirazol (tio)carboxamidas y sus analogos heterosustituidos.
US9181198B2 (en) 2010-07-29 2015-11-10 Oryzon Genomics S.A. Arylcyclopropylamine based demethylase inhibitors of LSD1 and their medical use
WO2012013727A1 (en) * 2010-07-29 2012-02-02 Oryzon Genomics S.A. Cyclopropylamine derivatives useful as lsd1 inhibitors
WO2012045883A1 (en) 2010-10-08 2012-04-12 Oryzon Genomics S.A. Cyclopropylamine inhibitors of oxidases
WO2012072713A2 (en) 2010-11-30 2012-06-07 Oryzon Genomics, S.A. Lysine demethylase inhibitors for diseases and disorders associated with flaviviridae
EP2712315B1 (en) 2011-02-08 2021-11-24 Oryzon Genomics, S.A. Lysine demethylase inhibitors for myeloproliferative disorders
CN107266345B (zh) 2011-10-20 2021-08-17 奥瑞泽恩基因组学股份有限公司 作为lsd1抑制剂的(杂)芳基环丙胺化合物
RS58475B1 (sr) 2011-10-20 2019-04-30 Oryzon Genomics Sa Jedinjenja (hetero)aril ciklopropilamina kao lsd1 inhibitori
WO2013120940A2 (en) 2012-02-14 2013-08-22 Syngenta Participations Ag Novel compounds
EP2740474A1 (en) 2012-12-05 2014-06-11 Instituto Europeo di Oncologia S.r.l. Cyclopropylamine derivatives useful as inhibitors of histone demethylases kdm1a
TW201507722A (zh) 2013-04-30 2015-03-01 Bayer Cropscience Ag 做為殺線蟲劑及殺體內寄生蟲劑的n-(2-鹵素-2-苯乙基)-羧醯胺類
KR20200100725A (ko) * 2017-12-20 2020-08-26 신젠타 파티서페이션즈 아게 식물병원성 미생물에 의한 채소, 토마토 및 감자 식물의 감염증을 방제하거나 예방하는 방법
AR117169A1 (es) * 2018-11-28 2021-07-14 Bayer Ag (tio)amidas de piridazina como compuestos fungicidas
BR112022022595A2 (pt) 2020-05-06 2022-12-20 Bayer Ag Piridina (tio)amidas como compostos fungicidas
EP4149929A1 (en) 2020-05-12 2023-03-22 Bayer Aktiengesellschaft Triazine and pyrimidine (thio)amides as fungicidal compounds
EP4153566A1 (en) 2020-05-19 2023-03-29 Bayer CropScience Aktiengesellschaft Azabicyclic(thio)amides as fungicidal compounds
CN115697059A (zh) 2020-05-27 2023-02-03 拜耳公司 活性化合物组合
WO2023078915A1 (en) 2021-11-03 2023-05-11 Bayer Aktiengesellschaft Bis(hetero)aryl thioether (thio)amides as fungicidal compounds

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849769A (en) * 1994-08-24 1998-12-15 Medivir Ab N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection
JP3844533B2 (ja) 1995-12-15 2006-11-15 日本曹達株式会社 2,6−ジクロロイソニコチン酸フェネチルアミド誘導体及び植物病害防除剤
FR2784375B1 (fr) 1998-10-12 2000-11-24 Adir Nouveaux derives cycliques a chaine cycloalkylenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA2353627C (en) * 1998-11-04 2010-10-26 Keiichi Imamura Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component
EP1388535A1 (en) * 2002-08-07 2004-02-11 Aventis Pharma Deutschland GmbH Acylated arylcycloalkylamines and their use as pharmaceuticals
US7186735B2 (en) * 2002-08-07 2007-03-06 Sanofi-Aventis Deutschland Gmbh Acylated arylcycloalkylamines and their use as pharmaceuticals
EP1591442A1 (en) * 2004-04-26 2005-11-02 Bayer CropScience S.A. 2-Pyridinycycloalkylbenzamide derivatives and their use as fungicides
WO2005103006A1 (en) * 2004-04-26 2005-11-03 Bayer Cropscience Sa 2-pyridinylcycloalkylcarboxamide derivatives useful as fungicides
WO2006122952A1 (en) 2005-05-18 2006-11-23 Bayer Cropscience Sa 2-pyridinylcycloalkylbenzamide derivatives and their use as fungicides
US8071629B2 (en) 2005-05-18 2011-12-06 Bayer Cropscience Ag 2-pyridinylcycloalkylcarboxamide derivatives as fungicides

Also Published As

Publication number Publication date
TW200804291A (en) 2008-01-16
DE602007003343D1 (de) 2009-12-31
US20100022570A1 (en) 2010-01-28
CN101466671A (zh) 2009-06-24
TWI388547B (zh) 2013-03-11
WO2007134799A1 (en) 2007-11-29
CA2650795A1 (en) 2007-11-29
BRPI0712027A2 (pt) 2012-01-03
ATE449068T1 (de) 2009-12-15
EP2018367A1 (en) 2009-01-28
ES2335319T3 (es) 2010-03-24
GT200700041A (es) 2008-02-05
KR20090019846A (ko) 2009-02-25
MX2008014534A (es) 2008-11-27
KR101380139B1 (ko) 2014-04-01
BRPI0712027B1 (pt) 2015-12-15
EP2018367B1 (en) 2009-11-18
US8618023B2 (en) 2013-12-31
JP5155303B2 (ja) 2013-03-06
CN101466671B (zh) 2012-01-11
JP2009537469A (ja) 2009-10-29

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