AR060935A1 - Metodos para tratar enfermedades autoinmunes utilizando una molecula de fusion taci- ig - Google Patents
Metodos para tratar enfermedades autoinmunes utilizando una molecula de fusion taci- igInfo
- Publication number
- AR060935A1 AR060935A1 ARP070102090A ARP070102090A AR060935A1 AR 060935 A1 AR060935 A1 AR 060935A1 AR P070102090 A ARP070102090 A AR P070102090A AR P070102090 A ARP070102090 A AR P070102090A AR 060935 A1 AR060935 A1 AR 060935A1
- Authority
- AR
- Argentina
- Prior art keywords
- taci
- methods
- autoimmune diseases
- fusion
- molecula
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/242—Gold; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74727006P | 2006-05-15 | 2006-05-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR060935A1 true AR060935A1 (es) | 2008-07-23 |
Family
ID=38694783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP070102090A AR060935A1 (es) | 2006-05-15 | 2007-05-15 | Metodos para tratar enfermedades autoinmunes utilizando una molecula de fusion taci- ig |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8784812B2 (enExample) |
| EP (1) | EP2035028A2 (enExample) |
| JP (2) | JP2009537563A (enExample) |
| KR (1) | KR20090016707A (enExample) |
| CN (1) | CN101489573B (enExample) |
| AR (1) | AR060935A1 (enExample) |
| AU (1) | AU2007249223B2 (enExample) |
| BR (1) | BRPI0711823A2 (enExample) |
| CA (1) | CA2651791A1 (enExample) |
| EA (1) | EA015342B1 (enExample) |
| EC (1) | ECSP088982A (enExample) |
| IL (1) | IL195243A0 (enExample) |
| MX (1) | MX2008014365A (enExample) |
| NZ (1) | NZ572373A (enExample) |
| UA (1) | UA98462C2 (enExample) |
| WO (1) | WO2007134326A2 (enExample) |
| ZA (1) | ZA200809202B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8852591B2 (en) | 2007-03-27 | 2014-10-07 | Zymogenetics, Inc. | Combination of BLyS and/or APRIL inhibition and immunosuppressants for treatment of autoimmune disease |
| PT2167038T (pt) * | 2007-06-13 | 2018-06-01 | Zymogenetics Inc | Utilização de proteína de fusão taci-ig, tal como atacicept para o fabrico de um medicamento para tratar lúpus eritematoso |
| EP2233149B1 (en) | 2007-10-16 | 2016-02-10 | ZymoGenetics, Inc. | Combination of transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) and anti-CD20 agents for treatment of autoimmune disease |
| WO2011109280A1 (en) * | 2010-03-05 | 2011-09-09 | Lerner Research Institute | Methods and compositions to treat immune-mediated disorders |
| CN103458776B (zh) * | 2010-11-26 | 2016-06-08 | 血液公司 | 用于确定疾病活动的系统 |
| US20170247462A1 (en) | 2014-07-03 | 2017-08-31 | Oklahoma Medical Research Foundation | Treatment of multiple sclerosis and neuromyelitis optica |
| PE20230494A1 (es) | 2020-05-08 | 2023-03-23 | Alpine Immune Sciences Inc | Proteinas inmunomoduladoras inhibidoras de april y baff y metodos de uso de las mismas |
| JP2024514077A (ja) * | 2021-03-31 | 2024-03-28 | 江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 | 切断したtaciポリペプチド及びその融合タンパク質並びに使用 |
| IL308336A (en) * | 2021-05-07 | 2024-01-01 | Alpine Immune Sciences Inc | Methods of dosing and treatment with TACI-FC modulatory fusion protein |
| US20240018212A1 (en) * | 2021-09-30 | 2024-01-18 | RemeGen Co., Ltd | Method for treating sjogren's syndrome using taci-fc fusion protein |
| WO2024159715A1 (zh) * | 2023-01-31 | 2024-08-08 | 荣昌生物制药(烟台)股份有限公司 | 用TACI-Fc融合蛋白治疗IgG4相关性疾病的方法 |
| TW202525840A (zh) * | 2023-09-28 | 2025-07-01 | 大陸商榮昌生物製藥(煙臺)股份有限公司 | 用TACI-Fc融合蛋白治療抗體介導性排斥反應的方法 |
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| DK1297013T3 (da) | 2000-04-27 | 2006-12-27 | Biogen Idec Inc | Anvendelse af TACI som antitumormiddel |
| AU2001263114A1 (en) | 2000-05-12 | 2001-11-26 | Amgen Inc | Methods and compositions of matter concerning april/g70, bcma, blys/agp-3, and taci |
| AU8009601A (en) | 2000-08-11 | 2002-02-25 | Kirin Brewery | Polypeptides controlling phosphoric acid metabolism, calcium metabolism, calcification and vitamin d metabolism and dnas encoding the same |
| AU2002230659A1 (en) * | 2000-11-07 | 2002-05-21 | Zymogenetics Inc. | Human tumor necrosis factor receptor |
| US20030012783A1 (en) | 2001-02-20 | 2003-01-16 | Wayne Kindsvogel | Antibodies that bind both BCMA and TACI |
| ATE446771T1 (de) * | 2001-05-24 | 2009-11-15 | Zymogenetics Inc | Taci-immunoglobulin-fusionsproteine |
| WO2003014294A2 (en) | 2001-08-03 | 2003-02-20 | Genentech, Inc. | Tacis and br3 polypeptides and uses thereof |
| NZ570777A (en) | 2002-05-17 | 2009-04-30 | Celgene Corp | Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases |
| US20050163775A1 (en) * | 2003-06-05 | 2005-07-28 | Genentech, Inc. | Combination therapy for B cell disorders |
| PT1631313E (pt) * | 2003-06-05 | 2015-07-02 | Genentech Inc | Terapêutica de combinação para distúrbios de células b |
| MXPA06004301A (es) | 2003-10-20 | 2006-06-05 | Biogen Idec Inc | Regimenes terapeuticos para antagonistas del factor de activacion de celulas b. |
| US8808696B2 (en) | 2005-08-09 | 2014-08-19 | Ares Trading S.A. | Methods for the treatment and prevention of abnormal cell proliferation using TACI-fusion molecules |
| CA2618765A1 (en) | 2005-08-09 | 2007-02-15 | Zymogenetics, Inc. | Methods for treating b-cell malignancies using taci-ig fusion molecule |
-
2007
- 2007-05-15 AR ARP070102090A patent/AR060935A1/es unknown
- 2007-05-15 BR BRPI0711823-6A patent/BRPI0711823A2/pt not_active IP Right Cessation
- 2007-05-15 EA EA200870535A patent/EA015342B1/ru not_active IP Right Cessation
- 2007-05-15 AU AU2007249223A patent/AU2007249223B2/en not_active Ceased
- 2007-05-15 NZ NZ572373A patent/NZ572373A/en not_active IP Right Cessation
- 2007-05-15 UA UAA200814333A patent/UA98462C2/ru unknown
- 2007-05-15 CA CA002651791A patent/CA2651791A1/en not_active Abandoned
- 2007-05-15 EP EP07797482A patent/EP2035028A2/en not_active Ceased
- 2007-05-15 KR KR1020087030524A patent/KR20090016707A/ko not_active Ceased
- 2007-05-15 CN CN2007800262144A patent/CN101489573B/zh not_active Expired - Fee Related
- 2007-05-15 US US11/748,978 patent/US8784812B2/en not_active Expired - Fee Related
- 2007-05-15 MX MX2008014365A patent/MX2008014365A/es not_active Application Discontinuation
- 2007-05-15 JP JP2009511209A patent/JP2009537563A/ja active Pending
- 2007-05-15 WO PCT/US2007/068982 patent/WO2007134326A2/en not_active Ceased
-
2008
- 2008-10-27 ZA ZA2008/09202A patent/ZA200809202B/en unknown
- 2008-11-12 IL IL195243A patent/IL195243A0/en not_active IP Right Cessation
- 2008-12-12 EC EC2008008982A patent/ECSP088982A/es unknown
-
2013
- 2013-01-04 JP JP2013000231A patent/JP2013100313A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2035028A2 (en) | 2009-03-18 |
| BRPI0711823A2 (pt) | 2012-01-17 |
| NZ572373A (en) | 2012-02-24 |
| EA200870535A1 (ru) | 2009-04-28 |
| CN101489573A (zh) | 2009-07-22 |
| JP2013100313A (ja) | 2013-05-23 |
| US8784812B2 (en) | 2014-07-22 |
| WO2007134326A3 (en) | 2008-04-17 |
| UA98462C2 (ru) | 2012-05-25 |
| ZA200809202B (en) | 2009-12-30 |
| AU2007249223A1 (en) | 2007-11-22 |
| AU2007249223B2 (en) | 2012-08-02 |
| US20070274984A1 (en) | 2007-11-29 |
| MX2008014365A (es) | 2008-11-27 |
| KR20090016707A (ko) | 2009-02-17 |
| EA015342B1 (ru) | 2011-06-30 |
| WO2007134326A2 (en) | 2007-11-22 |
| CN101489573B (zh) | 2013-05-22 |
| JP2009537563A (ja) | 2009-10-29 |
| IL195243A0 (en) | 2011-08-01 |
| CA2651791A1 (en) | 2007-11-22 |
| ECSP088982A (es) | 2009-01-30 |
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