AR054392A1 - Hemifumarato de 6- cloro-5-(2,6-difluoro-4-(3-(metilamino) proxi) fenil)-2-pirazin-2-il-n-((1s)-2,2,2-trifluoro-1-metiletil) pirimidin -4- amina, procesos para su preparcion, compuesto del hemifumarato, metodo para tratar o inhibir el crecimiento de celulas de tumor cancerosas y enfermedades asociad - Google Patents

Hemifumarato de 6- cloro-5-(2,6-difluoro-4-(3-(metilamino) proxi) fenil)-2-pirazin-2-il-n-((1s)-2,2,2-trifluoro-1-metiletil) pirimidin -4- amina, procesos para su preparcion, compuesto del hemifumarato, metodo para tratar o inhibir el crecimiento de celulas de tumor cancerosas y enfermedades asociad

Info

Publication number
AR054392A1
AR054392A1 ARP060102470A ARP060102470A AR054392A1 AR 054392 A1 AR054392 A1 AR 054392A1 AR P060102470 A ARP060102470 A AR P060102470A AR P060102470 A ARP060102470 A AR P060102470A AR 054392 A1 AR054392 A1 AR 054392A1
Authority
AR
Argentina
Prior art keywords
formula
phenyl
hemifumarate
amine
reacting
Prior art date
Application number
ARP060102470A
Other languages
English (en)
Spanish (es)
Inventor
David Michael Blum
Yanzhong Wu
Jean Schmid
Timothy Doyle
Jay Thomas Afragola
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37074929&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR054392(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of AR054392A1 publication Critical patent/AR054392A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ARP060102470A 2005-06-13 2006-06-12 Hemifumarato de 6- cloro-5-(2,6-difluoro-4-(3-(metilamino) proxi) fenil)-2-pirazin-2-il-n-((1s)-2,2,2-trifluoro-1-metiletil) pirimidin -4- amina, procesos para su preparcion, compuesto del hemifumarato, metodo para tratar o inhibir el crecimiento de celulas de tumor cancerosas y enfermedades asociad AR054392A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69001605P 2005-06-13 2005-06-13
US80278106P 2006-05-24 2006-05-24

Publications (1)

Publication Number Publication Date
AR054392A1 true AR054392A1 (es) 2007-06-20

Family

ID=37074929

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060102470A AR054392A1 (es) 2005-06-13 2006-06-12 Hemifumarato de 6- cloro-5-(2,6-difluoro-4-(3-(metilamino) proxi) fenil)-2-pirazin-2-il-n-((1s)-2,2,2-trifluoro-1-metiletil) pirimidin -4- amina, procesos para su preparcion, compuesto del hemifumarato, metodo para tratar o inhibir el crecimiento de celulas de tumor cancerosas y enfermedades asociad

Country Status (12)

Country Link
EP (1) EP1891052A1 (fr)
JP (1) JP2008543838A (fr)
AR (1) AR054392A1 (fr)
AU (1) AU2006259663A1 (fr)
BR (1) BRPI0612145A2 (fr)
CA (1) CA2610416A1 (fr)
GT (1) GT200600257A (fr)
MX (1) MX2007015718A (fr)
PE (1) PE20070114A1 (fr)
SV (1) SV2007002573A (fr)
TW (1) TW200716613A (fr)
WO (1) WO2006138180A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2581207T3 (es) 2009-11-12 2016-09-02 Tube Pharmaceuticals Gmbh Inhibidores de la tubulina
EP2903436B1 (fr) * 2012-09-19 2019-07-17 The Trustees Of The University Of Pennsylvania Composés hétérocycliques et leur utilisation pour le traitement de tauopathies neurodégénératives
WO2017181974A1 (fr) * 2016-04-20 2017-10-26 苏州苏领生物医药有限公司 Composé hétérocyclique à cinq chaînons, procédé de préparation correspondant, composition pharmaceutique et utilisation
WO2019169111A1 (fr) 2018-03-02 2019-09-06 The Trustees Of The University Of Pennsylvania Composés de [1,2,4]triazolo[1,5-a]pyrimidine et utilisation de ces derniers dans la stabilisation de microtubules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA06003207A (es) * 2003-09-24 2006-06-23 Wyeth Corp 5-arilpirimidinas como agentes anti-cancer.
CN100519559C (zh) * 2003-09-24 2009-07-29 惠氏控股公司 作为抗癌剂的6-[(经取代的)苯基]三唑并嘧啶

Also Published As

Publication number Publication date
AU2006259663A1 (en) 2006-12-28
SV2007002573A (es) 2007-01-03
PE20070114A1 (es) 2007-02-03
BRPI0612145A2 (pt) 2010-10-19
TW200716613A (en) 2007-05-01
EP1891052A1 (fr) 2008-02-27
JP2008543838A (ja) 2008-12-04
GT200600257A (es) 2007-02-14
MX2007015718A (es) 2008-02-21
CA2610416A1 (fr) 2006-12-28
WO2006138180A1 (fr) 2006-12-28

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