GT200600257A - Inhibidor de tubulina y proceso para su preparacion - Google Patents

Inhibidor de tubulina y proceso para su preparacion

Info

Publication number
GT200600257A
GT200600257A GT200600257A GT200600257A GT200600257A GT 200600257 A GT200600257 A GT 200600257A GT 200600257 A GT200600257 A GT 200600257A GT 200600257 A GT200600257 A GT 200600257A GT 200600257 A GT200600257 A GT 200600257A
Authority
GT
Guatemala
Prior art keywords
tubulin inhibitor
preparation
hemifumarate
mettiletil
propoxi
Prior art date
Application number
GT200600257A
Other languages
English (en)
Inventor
David Michael Blum
Yanzhong Wu
Jean Schmid
Timothy John Doyle
Jay Thomas Afragola
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37074929&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GT200600257(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of GT200600257A publication Critical patent/GT200600257A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA INVENCIÓN SUMINISTRA HEMIFUMARATO DE 6-CLORO-5-(2, 6-DIFLUORO-4-(3-METILAMINO)-PROPOXI)-FENIL)-2-PIRAZIN-2-IL- N-((1S)-2,2,2-TRIFLUORO-1-METILETIL)-PIRIMIDIN-4-AMINA QUE ES UN INHIBIDOR DE TUBULINA ÚTIL EN EL TRATAMINETO DEL CÁNCER Y PROCESOS DE FABRICACIÓN DE DICHO HEMIFUMARATO. T2006
GT200600257A 2005-06-13 2006-06-13 Inhibidor de tubulina y proceso para su preparacion GT200600257A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69001605P 2005-06-13 2005-06-13
US80278106P 2006-05-24 2006-05-24

Publications (1)

Publication Number Publication Date
GT200600257A true GT200600257A (es) 2007-02-14

Family

ID=37074929

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200600257A GT200600257A (es) 2005-06-13 2006-06-13 Inhibidor de tubulina y proceso para su preparacion

Country Status (12)

Country Link
EP (1) EP1891052A1 (es)
JP (1) JP2008543838A (es)
AR (1) AR054392A1 (es)
AU (1) AU2006259663A1 (es)
BR (1) BRPI0612145A2 (es)
CA (1) CA2610416A1 (es)
GT (1) GT200600257A (es)
MX (1) MX2007015718A (es)
PE (1) PE20070114A1 (es)
SV (1) SV2007002573A (es)
TW (1) TW200716613A (es)
WO (1) WO2006138180A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011057805A1 (en) 2009-11-12 2011-05-19 R&D Biopharmaceuticals Gmbh Tubulin inhibitors
EP2903436B1 (en) * 2012-09-19 2019-07-17 The Trustees Of The University Of Pennsylvania Heterocyclic compounds and their use for the treatment of neurodegenerative tauopathies
WO2017181974A1 (zh) * 2016-04-20 2017-10-26 苏州苏领生物医药有限公司 五元杂环类化合物及其制备方法、药物组合物和用途
US11623927B2 (en) 2018-03-02 2023-04-11 The Trustees Of The University Of Pennsylvania Substituted [1,2,4]triazolo[1,5-a]pyrimidines for stabilizing microtubules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1680425E (pt) * 2003-09-24 2007-02-28 Wyeth Corp 6 - [fenil (substituído)] triazolopirimidinas como agentes contra o cancro.
RU2006107578A (ru) * 2003-09-24 2007-10-27 Вайет Холдингз Корпорейшн (Us) 6-арилпиримидин, применяемый в качестве противоракового агента

Also Published As

Publication number Publication date
AR054392A1 (es) 2007-06-20
TW200716613A (en) 2007-05-01
BRPI0612145A2 (pt) 2010-10-19
SV2007002573A (es) 2007-01-03
WO2006138180A1 (en) 2006-12-28
PE20070114A1 (es) 2007-02-03
EP1891052A1 (en) 2008-02-27
JP2008543838A (ja) 2008-12-04
MX2007015718A (es) 2008-02-21
CA2610416A1 (en) 2006-12-28
AU2006259663A1 (en) 2006-12-28

Similar Documents

Publication Publication Date Title
CL2008000822A1 (es) Metodo para el tratamiento de la obesidad usando un inhibidor sglt2.
CL2007002384A1 (es) Uso de compuestos derivados de 2,5-dihidroxibenceno para el tratamiento de la psoriasis.
CR20140313A (es) Compuestos de biaril éter urea
CL2016002589A1 (es) Uso del compuesto genz-112638 (eliglustat), inhibidor de glucosilceramida sintasa, en el tratamiento de la enfermedad de gaucher y enfermedad de fabry (divisional de solicitud 201201348).
BRPI0817307A2 (pt) Processo para a fabricação de uma chapa de metal.
HN2006000971A (es) Metodos para preparar composiciones o formas de dosificacion que comprenden un agonista grp119 que tiene el efecto de un secretagogo glp-1
BRPI0714539B8 (pt) processo para obtenção de forma de dosagem farmaceutica de liberação prolongada de opioides
MX2009006536A (es) Compuestos de heteroaril-heteroarilo como inhibidores de cdk para el tratamiento de cancer, inflamacion e infecciones virales.
UY30846A1 (es) Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos
ECSP077321A (es) Procesos e intermediarios para preparar inhibidores de cisteína proteasa
BRPI0408922B1 (pt) processo para o tratamento termomecánico de aço.
CL2007002380A1 (es) Uso de compuestos derivados de 2,5-dihidroxibenceno para el tratamiento terapeutico y/o profilactico de la queratosis actinica.
BRPI0709769B8 (pt) implantes biodegradáveis para o tratamento de estados associados à dopamina
AR048235A1 (es) Un procedimiento para la sintesis de (7-metoxi-3,4-dihidro-1-naftalenil)acetonitrilo y su aplicacion en la sintesis de agomelatina
AR058579A1 (es) Proceso para preparar desvenlafaxina
DE602006013945D1 (de) Substituierte cyclopentane oder cyclopentanone zur behandlung von augenhochdruck
CL2007002387A1 (es) Uso de compuestos derivados de 2,5-dihidroxibenceno para el tratamiento de artritis y dolor.
MY139833A (en) Reticle alignment and overlay for multiple reticle process
GT200600257A (es) Inhibidor de tubulina y proceso para su preparacion
UY29790A1 (es) Sales de diariloimidazola-4-carboxamidas, composiciones que las contienen, procesos de preparación y aplicaciones
UY29774A1 (es) Inhibidor de atm
ITRM20050047A1 (it) Procedimento per la produzione di energia e apparato per la sua attuazione.
NI200700175A (es) Procesos para la preparación de alcoholes de aminoetoxibencilo
AR064219A1 (es) Cuerpo moldeado que contiene titanio
GT200800066A (es) Derivados de 9-cloro-15-deoxiprostaglandina, procedimiento para su preparacion y su uso como medicamento.