SV2007002573A - Proceso para la preparacion de inhibidores de tubulina - Google Patents

Proceso para la preparacion de inhibidores de tubulina

Info

Publication number
SV2007002573A
SV2007002573A SV2006002573A SV2006002573A SV2007002573A SV 2007002573 A SV2007002573 A SV 2007002573A SV 2006002573 A SV2006002573 A SV 2006002573A SV 2006002573 A SV2006002573 A SV 2006002573A SV 2007002573 A SV2007002573 A SV 2007002573A
Authority
SV
El Salvador
Prior art keywords
preparation
tubulin inhibitors
formula
rent
compounds
Prior art date
Application number
SV2006002573A
Other languages
English (en)
Inventor
David Michael Blum
Yanzhong Wu
Jean Schmid
Timothy John Doyle
Jay Thomas Afragola
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37074929&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SV2007002573(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of SV2007002573A publication Critical patent/SV2007002573A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA INVENCIÓN ES UN PROCESO PAR LA PREPARACIÓN DE LOS COMPUESTOS DE LA FÓRMULA 1: (VER FÓRMULA) EN DONDE: EL --- ES UN ENLACE OPCIONAL; R1 ES CF3 O C2F5; R2 ES H O ALQUILO C1-C3; N ES UN ENTERO DE 2, 3 O 4; X ES CL O BR; R3 Y R4 SON CADA UNO INDEPENDIENTEMENTE H O ALQUILO C1-C3 EN DONDE DICHOS COMPUESTOS DE FÓRMULA I SON INHIBIDORES DE TUBILINA QUE SON ÚTILES EN EL TRATAMIENTO DE CÁNCER
SV2006002573A 2005-06-13 2006-06-13 Proceso para la preparacion de inhibidores de tubulina SV2007002573A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69001605P 2005-06-13 2005-06-13
US80278106P 2006-05-24 2006-05-24

Publications (1)

Publication Number Publication Date
SV2007002573A true SV2007002573A (es) 2007-01-03

Family

ID=37074929

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2006002573A SV2007002573A (es) 2005-06-13 2006-06-13 Proceso para la preparacion de inhibidores de tubulina

Country Status (12)

Country Link
EP (1) EP1891052A1 (es)
JP (1) JP2008543838A (es)
AR (1) AR054392A1 (es)
AU (1) AU2006259663A1 (es)
BR (1) BRPI0612145A2 (es)
CA (1) CA2610416A1 (es)
GT (1) GT200600257A (es)
MX (1) MX2007015718A (es)
PE (1) PE20070114A1 (es)
SV (1) SV2007002573A (es)
TW (1) TW200716613A (es)
WO (1) WO2006138180A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2581207T3 (es) 2009-11-12 2016-09-02 Tube Pharmaceuticals Gmbh Inhibidores de la tubulina
WO2014047257A2 (en) * 2012-09-19 2014-03-27 The Trustees Of The University Of Pennsylvania Heterocyclic compounds and their use for the treatment of neurodegenerative tauopathies
WO2017181974A1 (zh) * 2016-04-20 2017-10-26 苏州苏领生物医药有限公司 五元杂环类化合物及其制备方法、药物组合物和用途
US11623927B2 (en) 2018-03-02 2023-04-11 The Trustees Of The University Of Pennsylvania Substituted [1,2,4]triazolo[1,5-a]pyrimidines for stabilizing microtubules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1663241B1 (en) * 2003-09-24 2009-05-27 Wyeth Holdings Corporation 5-arylpyrimidines as anticancer agents
PT1680425E (pt) * 2003-09-24 2007-02-28 Wyeth Corp 6 - [fenil (substituído)] triazolopirimidinas como agentes contra o cancro.

Also Published As

Publication number Publication date
MX2007015718A (es) 2008-02-21
BRPI0612145A2 (pt) 2010-10-19
EP1891052A1 (en) 2008-02-27
AU2006259663A1 (en) 2006-12-28
PE20070114A1 (es) 2007-02-03
GT200600257A (es) 2007-02-14
WO2006138180A1 (en) 2006-12-28
CA2610416A1 (en) 2006-12-28
TW200716613A (en) 2007-05-01
AR054392A1 (es) 2007-06-20
JP2008543838A (ja) 2008-12-04

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