PE20070114A1 - Inhibidor de tubulina y proceso para su preparacion - Google Patents

Inhibidor de tubulina y proceso para su preparacion

Info

Publication number
PE20070114A1
PE20070114A1 PE2006000657A PE2006000657A PE20070114A1 PE 20070114 A1 PE20070114 A1 PE 20070114A1 PE 2006000657 A PE2006000657 A PE 2006000657A PE 2006000657 A PE2006000657 A PE 2006000657A PE 20070114 A1 PE20070114 A1 PE 20070114A1
Authority
PE
Peru
Prior art keywords
trifluoro
pirazin
react
phenyl
give
Prior art date
Application number
PE2006000657A
Other languages
English (en)
Spanish (es)
Inventor
David Michael Blum
Yanzhong Wu
Timothy John Doyle
Jay Thomas Afragola
Jean Schmid
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37074929&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20070114(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PE20070114A1 publication Critical patent/PE20070114A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PE2006000657A 2005-06-13 2006-06-13 Inhibidor de tubulina y proceso para su preparacion PE20070114A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69001605P 2005-06-13 2005-06-13
US80278106P 2006-05-24 2006-05-24

Publications (1)

Publication Number Publication Date
PE20070114A1 true PE20070114A1 (es) 2007-02-03

Family

ID=37074929

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2006000657A PE20070114A1 (es) 2005-06-13 2006-06-13 Inhibidor de tubulina y proceso para su preparacion

Country Status (12)

Country Link
EP (1) EP1891052A1 (fr)
JP (1) JP2008543838A (fr)
AR (1) AR054392A1 (fr)
AU (1) AU2006259663A1 (fr)
BR (1) BRPI0612145A2 (fr)
CA (1) CA2610416A1 (fr)
GT (1) GT200600257A (fr)
MX (1) MX2007015718A (fr)
PE (1) PE20070114A1 (fr)
SV (1) SV2007002573A (fr)
TW (1) TW200716613A (fr)
WO (1) WO2006138180A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9163060B2 (en) 2009-11-12 2015-10-20 R&D Biopharmaceuticals Gmbh Tubulin inhibitors
EP2903436B1 (fr) * 2012-09-19 2019-07-17 The Trustees Of The University Of Pennsylvania Composés hétérocycliques et leur utilisation pour le traitement de tauopathies neurodégénératives
WO2017181974A1 (fr) * 2016-04-20 2017-10-26 苏州苏领生物医药有限公司 Composé hétérocyclique à cinq chaînons, procédé de préparation correspondant, composition pharmaceutique et utilisation
WO2019169111A1 (fr) 2018-03-02 2019-09-06 The Trustees Of The University Of Pennsylvania Composés de [1,2,4]triazolo[1,5-a]pyrimidine et utilisation de ces derniers dans la stabilisation de microtubules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005030216A1 (fr) * 2003-09-24 2005-04-07 Wyeth Holdings Corporation 5-arylpyrimidines utilisees comme agents anticancereux
ES2279452T3 (es) * 2003-09-24 2007-08-16 Wyeth Holdings Corporation 6-((sustituido)fenil)triazolopirimidinas como agentes antineoplasicos.

Also Published As

Publication number Publication date
EP1891052A1 (fr) 2008-02-27
SV2007002573A (es) 2007-01-03
AR054392A1 (es) 2007-06-20
GT200600257A (es) 2007-02-14
BRPI0612145A2 (pt) 2010-10-19
CA2610416A1 (fr) 2006-12-28
AU2006259663A1 (en) 2006-12-28
JP2008543838A (ja) 2008-12-04
WO2006138180A1 (fr) 2006-12-28
TW200716613A (en) 2007-05-01
MX2007015718A (es) 2008-02-21

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