AR054215A1 - Una formulacion farmaceutica de un taxano, una composicion solida de un taxano liofilizado a partir de una solucion de acido acetico, un procedimiento para la preparacion de dicha composicion solida de un taxano, una composicion solubilizante de un taxano liofilizado, y un conjunto de elementos (kit - Google Patents
Una formulacion farmaceutica de un taxano, una composicion solida de un taxano liofilizado a partir de una solucion de acido acetico, un procedimiento para la preparacion de dicha composicion solida de un taxano, una composicion solubilizante de un taxano liofilizado, y un conjunto de elementos (kitInfo
- Publication number
- AR054215A1 AR054215A1 AR20060100208A ARP060100208A AR054215A1 AR 054215 A1 AR054215 A1 AR 054215A1 AR 20060100208 A AR20060100208 A AR 20060100208A AR P060100208 A ARP060100208 A AR P060100208A AR 054215 A1 AR054215 A1 AR 054215A1
- Authority
- AR
- Argentina
- Prior art keywords
- taxane
- composition
- solid composition
- acetic acid
- solution
- Prior art date
Links
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 title abstract 18
- 229940123237 Taxane Drugs 0.000 title abstract 11
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title abstract 11
- 239000008247 solid mixture Substances 0.000 title abstract 7
- 239000000203 mixture Substances 0.000 title abstract 5
- 230000003381 solubilizing effect Effects 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000000243 solution Substances 0.000 abstract 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 abstract 2
- 238000004108 freeze drying Methods 0.000 abstract 2
- 239000002736 nonionic surfactant Substances 0.000 abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 2
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 abstract 1
- 239000003613 bile acid Substances 0.000 abstract 1
- 239000003978 infusion fluid Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Epoxy Compounds (AREA)
Priority Applications (28)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AR20060100208A AR054215A1 (es) | 2006-01-20 | 2006-01-20 | Una formulacion farmaceutica de un taxano, una composicion solida de un taxano liofilizado a partir de una solucion de acido acetico, un procedimiento para la preparacion de dicha composicion solida de un taxano, una composicion solubilizante de un taxano liofilizado, y un conjunto de elementos (kit |
| US12/161,625 US20090215883A1 (en) | 2006-01-20 | 2007-01-18 | Pharmaceutical formulation comprising taxane, a solid composition of taxane, a process for preparing said solid composition of taxane, a solubilizing composition of said solid composition of taxane, and a kit for the injectable formulation of taxane |
| MX2008009358A MX2008009358A (es) | 2006-01-20 | 2007-01-18 | Una formulacion farmaceutica de taxano, una composicion solida de taxano, un procedimiento para la preparacion de dicha composicion solida de taxano, una composicion solubllizante de dicha composicion solida de taxano, y un conjunto de elementos (kit |
| CA002637893A CA2637893A1 (en) | 2006-01-20 | 2007-01-18 | Taxane pharmaceutical formulation, solid taxane composition, method for preparing the solid taxane composition, composition for solubilising said solid taxane composition and set of elements (kit) for the injectable taxane formulation |
| EP07712569A EP1994925A4 (en) | 2006-01-20 | 2007-01-18 | PHARMACEUTICAL TAX FORMULATION, TAXAN SOLID-MATERIAL COMPOSITION, METHOD FOR PRODUCING TAXAN SOLID-MATERIAL COMPOSITION, COMPOSITION FOR SOLUBILIZING THE TAXAN SOLID-MATERIAL COMPOSITION, AND ELEMENT SET (KIT) FOR INJECTABLE TAX FORMULATION |
| RU2008133761/15A RU2429837C2 (ru) | 2006-01-20 | 2007-01-18 | Фармацевтический состав таксана, твердая композиция таксана, способ получения твердой композиции таксана, композиция для солюбилизации указанной твердой композиции таксана и комплект элементов (набор) для состава таксана для инъекций |
| AU2007206876A AU2007206876B2 (en) | 2006-01-20 | 2007-01-18 | Taxane pharmaceutical formulation, solid taxane composition, method for preparing the solid taxane composition, composition for solubilising said solid taxane composition and set of elements (kit) for the injectable taxane formulation |
| JP2008550785A JP2009523770A (ja) | 2006-01-20 | 2007-01-18 | タキサン医薬製剤、固形タキサン組成物、前記固形タキサン組成物の調製方法、前記固形タキサン組成物を可溶化するための組成物および注射可能なタキサン製剤のための構成要素のセット（キット） |
| NZ569783A NZ569783A (en) | 2006-01-20 | 2007-01-18 | Surfactant-free freeze-dried solid taxane composition |
| BRPI0706931-6A BRPI0706931A2 (pt) | 2006-01-20 | 2007-01-18 | uma formulação farmacêutica que compreende um taxano, uma composição sólida de taxano, um processo para preparar dita composição sólida de taxano, uma composição de solubulização de dita composição de taxano, e um kit de formulação injetável de taxano |
| PCT/ES2007/070012 WO2007082978A1 (es) | 2006-01-20 | 2007-01-18 | Una formulación farmacéutica de taxano, una composición sólida de taxano, un procedimiento para la preparación de dicha composición sólida de taxano, una composición solubilizante de dicha composición sólida de taxano, y un conjunto de elementos (kit) par |
| BRPI0706932-4A BRPI0706932A2 (pt) | 2006-01-20 | 2007-01-19 | composição sólida de taxano liofilizada, procedimento para preparar dita composição sólida, formulação farmaçêutica e conjunto (kit) de dita formulação |
| CA002638034A CA2638034A1 (en) | 2006-01-20 | 2007-01-19 | A lyophilized solid taxane composition, a process for preparing said solid composition, a pharmaceutical formulation and a kit of said formulation |
| JP2008550786A JP2009523771A (ja) | 2006-01-20 | 2007-01-19 | 凍結乾燥した個体状タキサン類組成物、前記組成物を生成する方法、前記組成物の医薬調剤、前記組成物の調剤用キット。 |
| MX2008009357A MX2008009357A (es) | 2006-01-20 | 2007-01-19 | Una composicion solida de taxano liofilizada, un procedimiento para preparar dicha composicion solida, una formulacion farmaceuctica y un conjunto (kit) de dicha formulacion. |
| PCT/ES2007/070013 WO2007082979A1 (es) | 2006-01-20 | 2007-01-19 | Una composición sólida de taxano liofilizada, un procedimiento para preparar dicha composición sólida, una formulación farmacéutica y un conjunto (kit) de dicha formulación |
| EP07712570A EP1982699A1 (en) | 2006-01-20 | 2007-01-19 | A solid lyophilized taxane composition, a method for preparing said solid composition, a pharmaceutical formulation and a kit for said formulation |
| PE2007000062A PE20070945A1 (es) | 2006-01-20 | 2007-01-19 | Una formulacion farmaceutica de taxano, una composicion solida de taxano, un procedimiento para la preparacion de dicha composicion solida de taxano, una composicion solubilizante de dicha composicion solida de taxano, y un conjunto de elementos (kit |
| UY30099A UY30099A1 (es) | 2006-01-20 | 2007-01-19 | Una composicion solida de taxano liofilizado, un procedimiento para preparar dicha composicion solida, una formulacion farmacéutica y un conjunto (kit) para la preparacion de una formulacion inyectable de taxano |
| UY30100A UY30100A1 (es) | 2006-01-20 | 2007-01-19 | Una formulacion farmacéutica de taxano, una composicion solida de taxano, un procedimiento para la preparacion de dicha composicion solida de taxano, una composicion solubilizante de dicha composicion solida de taxano, y un conjunto de elementos (kit |
| ZA200805704A ZA200805704B (en) | 2006-01-20 | 2007-01-19 | A solid lyophilized taxane composition, a method for preparing said solid composition, a pharmaceutical formulation and a kit for said formulation |
| PE2007000063A PE20071243A1 (es) | 2006-01-20 | 2007-01-19 | Una composicion solida de taxano liofilizada, un procedimiento para preparar dicha composicion solida, una formulacion farmaceutica y un conjunto (kit) para la preparacion de una formulacion inyectable de taxano |
| US12/161,609 US20090215882A1 (en) | 2006-01-20 | 2007-01-19 | Lyophilized solid taxane composition, a process for preparing said solid composition, a pharmaceutical formulation and a kit for said formulation |
| NZ569968A NZ569968A (en) | 2006-01-20 | 2007-01-19 | A solid lyophilized taxane composition, a method for preparing said solid composition, a pharmaceutical formulation and a kit for said formulation |
| AU2007206877A AU2007206877A1 (en) | 2006-01-20 | 2007-01-19 | A solid lyophilized taxane composition, a method for preparing said solid composition, a pharmaceutical formulation and a kit for said formulation |
| ZA200805989A ZA200805989B (en) | 2006-01-20 | 2008-07-09 | Taxane pharmaceutical formulation, solid taxane composition, method for preparing the solid taxane composition, composition for solubilising said solid taxane composition and set of elements (kit) for the injectable taxane formulation |
| GT200800145A GT200800145A (es) | 2006-01-20 | 2008-07-18 | Una composicion solida de taxano liofilizada, un procedimiento para preparar dicha composicion solida, una formulacion farmaceutica y un conjunto (kit) de dicha formulacion |
| GT200800146A GT200800146A (es) | 2006-01-20 | 2008-07-18 | Una formulacion farmaceutica de taxano, una composicion solida de taxano, un procedimiento para la preparacion de dicha composicion solida de taxano, una composicion solubilizante de dicha composicion solida de taxano, y un conjunto de elementos (kit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AR20060100208A AR054215A1 (es) | 2006-01-20 | 2006-01-20 | Una formulacion farmaceutica de un taxano, una composicion solida de un taxano liofilizado a partir de una solucion de acido acetico, un procedimiento para la preparacion de dicha composicion solida de un taxano, una composicion solubilizante de un taxano liofilizado, y un conjunto de elementos (kit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR054215A1 true AR054215A1 (es) | 2007-06-13 |
Family
ID=38134453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR20060100208A AR054215A1 (es) | 2006-01-20 | 2006-01-20 | Una formulacion farmaceutica de un taxano, una composicion solida de un taxano liofilizado a partir de una solucion de acido acetico, un procedimiento para la preparacion de dicha composicion solida de un taxano, una composicion solubilizante de un taxano liofilizado, y un conjunto de elementos (kit |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20090215883A1 (enExample) |
| EP (2) | EP1994925A4 (enExample) |
| JP (2) | JP2009523770A (enExample) |
| AR (1) | AR054215A1 (enExample) |
| AU (1) | AU2007206877A1 (enExample) |
| BR (2) | BRPI0706931A2 (enExample) |
| CA (2) | CA2637893A1 (enExample) |
| GT (2) | GT200800145A (enExample) |
| MX (2) | MX2008009358A (enExample) |
| NZ (2) | NZ569783A (enExample) |
| PE (2) | PE20070945A1 (enExample) |
| RU (1) | RU2429837C2 (enExample) |
| UY (2) | UY30099A1 (enExample) |
| WO (2) | WO2007082978A1 (enExample) |
| ZA (2) | ZA200805704B (enExample) |
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2006
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2007
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- 2007-01-18 EP EP07712569A patent/EP1994925A4/en not_active Withdrawn
- 2007-01-18 CA CA002637893A patent/CA2637893A1/en not_active Abandoned
- 2007-01-18 RU RU2008133761/15A patent/RU2429837C2/ru not_active IP Right Cessation
- 2007-01-18 WO PCT/ES2007/070012 patent/WO2007082978A1/es not_active Ceased
- 2007-01-18 MX MX2008009358A patent/MX2008009358A/es unknown
- 2007-01-18 BR BRPI0706931-6A patent/BRPI0706931A2/pt not_active IP Right Cessation
- 2007-01-18 US US12/161,625 patent/US20090215883A1/en not_active Abandoned
- 2007-01-18 NZ NZ569783A patent/NZ569783A/en not_active IP Right Cessation
- 2007-01-19 CA CA002638034A patent/CA2638034A1/en not_active Abandoned
- 2007-01-19 UY UY30099A patent/UY30099A1/es not_active Application Discontinuation
- 2007-01-19 AU AU2007206877A patent/AU2007206877A1/en not_active Abandoned
- 2007-01-19 PE PE2007000062A patent/PE20070945A1/es not_active Application Discontinuation
- 2007-01-19 JP JP2008550786A patent/JP2009523771A/ja not_active Abandoned
- 2007-01-19 NZ NZ569968A patent/NZ569968A/en not_active IP Right Cessation
- 2007-01-19 UY UY30100A patent/UY30100A1/es not_active Application Discontinuation
- 2007-01-19 US US12/161,609 patent/US20090215882A1/en not_active Abandoned
- 2007-01-19 EP EP07712570A patent/EP1982699A1/en not_active Withdrawn
- 2007-01-19 BR BRPI0706932-4A patent/BRPI0706932A2/pt not_active IP Right Cessation
- 2007-01-19 MX MX2008009357A patent/MX2008009357A/es not_active Application Discontinuation
- 2007-01-19 PE PE2007000063A patent/PE20071243A1/es not_active Application Discontinuation
- 2007-01-19 WO PCT/ES2007/070013 patent/WO2007082979A1/es not_active Ceased
- 2007-01-19 ZA ZA200805704A patent/ZA200805704B/xx unknown
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- 2008-07-18 GT GT200800145A patent/GT200800145A/es unknown
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Also Published As
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| JP2009523770A (ja) | 2009-06-25 |
| EP1982699A1 (en) | 2008-10-22 |
| GT200800145A (es) | 2009-07-21 |
| ZA200805989B (en) | 2009-05-27 |
| WO2007082979A1 (es) | 2007-07-26 |
| CA2637893A1 (en) | 2007-07-26 |
| BRPI0706931A2 (pt) | 2011-04-19 |
| EP1994925A4 (en) | 2013-01-23 |
| NZ569783A (en) | 2011-04-29 |
| UY30100A1 (es) | 2008-09-02 |
| EP1994925A1 (en) | 2008-11-26 |
| GT200800146A (es) | 2008-12-15 |
| ZA200805704B (en) | 2009-11-25 |
| JP2009523771A (ja) | 2009-06-25 |
| RU2008133761A (ru) | 2010-02-27 |
| NZ569968A (en) | 2011-07-29 |
| AU2007206877A1 (en) | 2007-07-26 |
| CA2638034A1 (en) | 2007-07-26 |
| US20090215882A1 (en) | 2009-08-27 |
| AU2007206876A1 (en) | 2007-07-26 |
| WO2007082978B1 (es) | 2007-09-07 |
| MX2008009357A (es) | 2008-09-10 |
| RU2429837C2 (ru) | 2011-09-27 |
| PE20071243A1 (es) | 2008-02-03 |
| BRPI0706932A2 (pt) | 2011-04-19 |
| US20090215883A1 (en) | 2009-08-27 |
| UY30099A1 (es) | 2008-09-02 |
| MX2008009358A (es) | 2008-09-10 |
| WO2007082978A1 (es) | 2007-07-26 |
| PE20070945A1 (es) | 2007-10-07 |
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