AR047455A1 - Compuestos de benzotiodiazina fluorados,procedimiento para su preparacion, composiciones farmaceuticas que los contienen y usos - Google Patents
Compuestos de benzotiodiazina fluorados,procedimiento para su preparacion, composiciones farmaceuticas que los contienen y usosInfo
- Publication number
- AR047455A1 AR047455A1 ARP050100244A ARP050100244A AR047455A1 AR 047455 A1 AR047455 A1 AR 047455A1 AR P050100244 A ARP050100244 A AR P050100244A AR P050100244 A ARP050100244 A AR P050100244A AR 047455 A1 AR047455 A1 AR 047455A1
- Authority
- AR
- Argentina
- Prior art keywords
- branched
- linear
- optionally substituted
- alkyl
- halogen atoms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
- C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
- C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
- C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
-
- A—HUMAN NECESSITIES
- A62—LIFE-SAVING; FIRE-FIGHTING
- A62C—FIRE-FIGHTING
- A62C13/00—Portable extinguishers which are permanently pressurised or pressurised immediately before use
- A62C13/76—Details or accessories
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Management (AREA)
- Business, Economics & Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Reivindicacion 1: Compuestos de formula (1), en la cual: RF representa un grupo monofluoro- o polifluoro-alquilo(C1-6) lineal o ramificado o un grupo monofluoro- o polifluoro-cicloalquilalquilo, donde la parte alquilo es C1-6 y lineal o ramificado, y la parte cicloalquilo es C3-7; R1 representa un átomo de hidrogeno o un grupo seleccionado entre alquilo C1-6 lineal o ramificado opcionalmente sustituido por uno o más átomos de halogeno, preferentemente fluor, y alquilaminocarbonilo C1-6 lineal o ramificado; R2 representa un átomo de hidrogeno o de halogeno o un grupo seleccionado entre alquilo C1-6 lineal o ramificado opcionalmente sustituido por uno o más átomos de halogeno, y cicloalquilo C3-7; R3, R4, R5 y R6, que pueden ser iguales o diferentes, representan, cada uno de ellos, un átomo o grupo seleccionado entre los átomos de hidrogeno y de halogeno y los grupos nitro, ciano, alquilsulfonilo C1-6 lineal o ramificado, hidroxi, alcoxi C1-5 lineal o ramificado, alquilo C1-6 lineal o ramificado opcionalmente sustituido por uno o más átomos de halogeno, y amino opcionalmente sustituido por uno o dos grupos alquilo lineal o ramificado; y también sus sales de adicion con un ácido o una base farmacéuticamente aceptable, y sus isomeros opticos cuando éstos están presentes, entendiéndose que R3 representa un átomo de hidrogeno cuando R6 no representa un átomo de hidrogeno.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0400689A FR2865474B1 (fr) | 2004-01-26 | 2004-01-26 | Nouveaux derives de benzothiazines fluorees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR047455A1 true AR047455A1 (es) | 2006-01-18 |
Family
ID=34630671
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050100244A AR047455A1 (es) | 2004-01-26 | 2005-01-25 | Compuestos de benzotiodiazina fluorados,procedimiento para su preparacion, composiciones farmaceuticas que los contienen y usos |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7268129B2 (es) |
| EP (1) | EP1557412A1 (es) |
| JP (1) | JP4291786B2 (es) |
| KR (1) | KR100668195B1 (es) |
| CN (1) | CN1308317C (es) |
| AR (1) | AR047455A1 (es) |
| AU (1) | AU2005200311A1 (es) |
| BR (1) | BRPI0500235A (es) |
| CA (1) | CA2492161C (es) |
| EA (1) | EA009698B1 (es) |
| FR (1) | FR2865474B1 (es) |
| GE (1) | GEP20063960B (es) |
| HK (1) | HK1079778A1 (es) |
| MA (1) | MA27545A1 (es) |
| MX (1) | MXPA05001019A (es) |
| NO (1) | NO20050391L (es) |
| NZ (1) | NZ537877A (es) |
| SG (1) | SG113569A1 (es) |
| UA (1) | UA86574C2 (es) |
| ZA (1) | ZA200500774B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2879201B1 (fr) * | 2004-12-10 | 2007-02-16 | Servier Lab | Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| HUE049460T2 (hu) | 2010-08-10 | 2020-09-28 | Takeda Pharmaceuticals Co | Heterociklusos vegyület és annak alkalmazása ampa receptor pozitív allosztérikus modulátorként |
| CN102977054A (zh) * | 2012-12-12 | 2013-03-20 | 中国药科大学 | 一类选择性α2A受体激动剂的治疗阿尔茨海默病用途 |
| CN114230471B (zh) * | 2021-11-09 | 2024-01-26 | 河北科技大学 | 一种3,4-二氯-2-氟苯胺的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5488049A (en) * | 1993-12-10 | 1996-01-30 | Fidia - Georgetown Institute For The Neuro-Sciences | Method of treating learning and memory disorders using benzothiadiazide derivatives as nootropic agents |
| US6083947A (en) * | 1996-01-29 | 2000-07-04 | The Regents Of The University Of California | Method for treating sexual dysfunctions |
| AU4345297A (en) * | 1996-09-17 | 1998-04-14 | Regents Of The University Of California, The | Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor |
| CA2320354A1 (en) * | 1998-02-18 | 1999-08-26 | Neurosearch A/S | Novel compounds and their use as positive ampa receptor modulators |
| FR2801587B1 (fr) * | 1999-11-30 | 2002-01-11 | Adir | Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| WO2003005978A1 (en) * | 2001-07-10 | 2003-01-23 | Sven Jarby | Remedy against skin diseases |
| FR2833950B1 (fr) * | 2001-12-21 | 2005-12-16 | Servier Lab | Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2856064B1 (fr) * | 2003-06-13 | 2005-08-19 | Servier Lab | Nouveaux derives de benzothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
-
2004
- 2004-01-26 FR FR0400689A patent/FR2865474B1/fr not_active Expired - Fee Related
-
2005
- 2005-01-10 CA CA2492161A patent/CA2492161C/fr not_active Expired - Fee Related
- 2005-01-19 SG SG200500253A patent/SG113569A1/en unknown
- 2005-01-24 MA MA28063A patent/MA27545A1/fr unknown
- 2005-01-24 GE GEAP8596A patent/GEP20063960B/en unknown
- 2005-01-24 EA EA200500072A patent/EA009698B1/ru not_active IP Right Cessation
- 2005-01-24 US US11/041,495 patent/US7268129B2/en not_active Expired - Fee Related
- 2005-01-25 KR KR1020050006775A patent/KR100668195B1/ko not_active IP Right Cessation
- 2005-01-25 NO NO20050391A patent/NO20050391L/no not_active Application Discontinuation
- 2005-01-25 MX MXPA05001019A patent/MXPA05001019A/es active IP Right Grant
- 2005-01-25 UA UAA200500666A patent/UA86574C2/ru unknown
- 2005-01-25 AU AU2005200311A patent/AU2005200311A1/en not_active Abandoned
- 2005-01-25 NZ NZ537877A patent/NZ537877A/en unknown
- 2005-01-25 AR ARP050100244A patent/AR047455A1/es unknown
- 2005-01-25 EP EP05290160A patent/EP1557412A1/fr not_active Withdrawn
- 2005-01-26 ZA ZA200500774A patent/ZA200500774B/xx unknown
- 2005-01-26 JP JP2005017813A patent/JP4291786B2/ja not_active Expired - Fee Related
- 2005-01-26 BR BR0500235-4A patent/BRPI0500235A/pt not_active IP Right Cessation
- 2005-01-26 CN CNB2005100029246A patent/CN1308317C/zh not_active Expired - Fee Related
- 2005-12-22 HK HK05111844A patent/HK1079778A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1557412A1 (fr) | 2005-07-27 |
| NO20050391D0 (no) | 2005-01-25 |
| HK1079778A1 (en) | 2006-04-13 |
| US20050165008A1 (en) | 2005-07-28 |
| JP4291786B2 (ja) | 2009-07-08 |
| MA27545A1 (fr) | 2005-10-03 |
| GEP20063960B (en) | 2006-11-10 |
| AU2005200311A1 (en) | 2005-08-11 |
| KR100668195B1 (ko) | 2007-01-11 |
| FR2865474B1 (fr) | 2008-06-13 |
| US7268129B2 (en) | 2007-09-11 |
| CA2492161C (fr) | 2010-06-22 |
| NO20050391L (no) | 2005-07-27 |
| KR20050077028A (ko) | 2005-07-29 |
| CN1308317C (zh) | 2007-04-04 |
| CN1680343A (zh) | 2005-10-12 |
| SG113569A1 (en) | 2005-08-29 |
| NZ537877A (en) | 2005-10-28 |
| JP2005232166A (ja) | 2005-09-02 |
| EA009698B1 (ru) | 2008-02-28 |
| ZA200500774B (en) | 2005-08-10 |
| EA200500072A1 (ru) | 2005-08-25 |
| UA86574C2 (ru) | 2009-05-12 |
| CA2492161A1 (fr) | 2005-07-26 |
| FR2865474A1 (fr) | 2005-07-29 |
| MXPA05001019A (es) | 2007-11-14 |
| BRPI0500235A (pt) | 2005-09-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR047823A1 (es) | Derivados de 1,2,3,4-tetrahidroisoquinolina sustituida | |
| AR088808A2 (es) | Derivados de 2h-piridazin-3-ona, composiciones farmaceuticas que los contienen y un proceso para la preparacion de dichos derivados y el uso de dichos derivados para la preparacion de una composicion farmaceutica | |
| AR062677A1 (es) | Derivados de biaril-sulfonamida, procesos de produccion y composiciones farmaceuticas que los comprenden | |
| ECSP12011867A (es) | Derivados bencimidazol-imidazol | |
| AR038379A1 (es) | Esteres de acidos fluoreno-carboxilicos, procedimientos para su preparacion asi como su utilizacion en calidad de medicamentos | |
| AR052866A1 (es) | Fenil-metanonas monociclicas sustituidas | |
| AR063988A1 (es) | Derivados heterociclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen | |
| UY26727A1 (es) | Derivados de tropano útiles en terapia | |
| AR057062A1 (es) | Moduladores de aminoquinolina y aminoquinazolina quinasa | |
| AR056337A1 (es) | Derivados de alquil-, alquenil- y alquinilcarbamatos, su preparacion y su aplicacion en terapeutica | |
| NO20054787L (no) | Indenderivater som farmasotiske midler | |
| AR054341A1 (es) | Combinaciones sinergicas de compuestos activos fungicidas | |
| UY30048A1 (es) | Derivados sustituidos de la n,2-(1h-benzimidazol-1-il) acetamida, composiciones farmacéuticas conteniéndolos, procesos de preparación y aplicaciones | |
| AR061835A1 (es) | Derivados tetraciclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen | |
| AR051392A1 (es) | Antagonistas no peptidicos de bradiquinina y composiciones farmaceuticas de los mismos | |
| AR033879A1 (es) | Compuesto sulfonamida, composicion farmaceutica que lo comprende, su uso para preparar dicha composicion y procedimiento para la obtencion de dicho compuesto | |
| SE0403171D0 (sv) | New compounds | |
| AR045155A1 (es) | Derivados de 6-indolilsulfonamidas, su preparacion y su aplicacion como medicamentos | |
| AR052308A1 (es) | Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto | |
| AR047455A1 (es) | Compuestos de benzotiodiazina fluorados,procedimiento para su preparacion, composiciones farmaceuticas que los contienen y usos | |
| AR045156A1 (es) | Derivados de 5-indolilsulfonamidas, su preparacion y su aplicacion como medicamentos | |
| AR051149A1 (es) | Compuestos de benzotiadiazina, un proceso para su preparacion y composiciones farmaceuticas que los contienen | |
| AR054121A1 (es) | Compuestos de fenilpiridilpiperazina, procedimiento de preparacion, composiciones farmaceuticas que los contienen, y usos farmacologicos como antagonistas de receptores histaminergicos h3 | |
| AR040133A1 (es) | Derivados de n-acilamino bencil eter | |
| AR052139A1 (es) | Formulaciones de benzotiazol y el uso de las mismas |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |