AR047144A1 - Derivados de 1-n-fenilamino-1h-imidazol y composiciones farmaceuticas que los contienen - Google Patents
Derivados de 1-n-fenilamino-1h-imidazol y composiciones farmaceuticas que los contienenInfo
- Publication number
- AR047144A1 AR047144A1 ARP040104657A ARP040104657A AR047144A1 AR 047144 A1 AR047144 A1 AR 047144A1 AR P040104657 A ARP040104657 A AR P040104657A AR P040104657 A ARP040104657 A AR P040104657A AR 047144 A1 AR047144 A1 AR 047144A1
- Authority
- AR
- Argentina
- Prior art keywords
- scsnr10
- tetrazolyl
- scsnr10r11
- sconr10r11
- oso2or10
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 5
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 5
- IQUPABOKLQSFBK-UHFFFAOYSA-N 2-nitrophenol Chemical group OC1=CC=CC=C1[N+]([O-])=O IQUPABOKLQSFBK-UHFFFAOYSA-N 0.000 abstract 4
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 4
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 3
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 3
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 abstract 3
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 3
- 125000005518 carboxamido group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical group 0.000 abstract 3
- 229910052760 oxygen Inorganic materials 0.000 abstract 3
- 229910052717 sulfur Inorganic materials 0.000 abstract 3
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 3
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 abstract 2
- IANQTJSKSUMEQM-UHFFFAOYSA-N 1-benzofuran Chemical compound C1=CC=C2OC=CC2=C1 IANQTJSKSUMEQM-UHFFFAOYSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NAWXUBYGYWOOIX-SFHVURJKSA-N (2s)-2-[[4-[2-(2,4-diaminoquinazolin-6-yl)ethyl]benzoyl]amino]-4-methylidenepentanedioic acid Chemical compound C1=CC2=NC(N)=NC(N)=C2C=C1CCC1=CC=C(C(=O)N[C@@H](CC(=C)C(O)=O)C(O)=O)C=C1 NAWXUBYGYWOOIX-SFHVURJKSA-N 0.000 abstract 1
- FURVSEVWPXHUEK-UHFFFAOYSA-N 1,2$l^{6},3-benzoxathiazine 2,2-dioxide Chemical compound C1=CC=C2C=NS(=O)(=O)OC2=C1 FURVSEVWPXHUEK-UHFFFAOYSA-N 0.000 abstract 1
- YSHIPIDAJXCIFS-UHFFFAOYSA-N 1,2,3-benzodithiazine Chemical compound C1=CC=C2C=NSSC2=C1 YSHIPIDAJXCIFS-UHFFFAOYSA-N 0.000 abstract 1
- GDUQJFXEJRHTJT-UHFFFAOYSA-N 1,2lambda4,3-benzoxathiazine 2-oxide Chemical compound C1=CC=C2C=NS(=O)OC2=C1 GDUQJFXEJRHTJT-UHFFFAOYSA-N 0.000 abstract 1
- FCEHBMOGCRZNNI-UHFFFAOYSA-N 1-benzothiophene Chemical group C1=CC=C2SC=CC2=C1 FCEHBMOGCRZNNI-UHFFFAOYSA-N 0.000 abstract 1
- HXQHRUJXQJEGER-UHFFFAOYSA-N 1-methylbenzotriazole Chemical compound C1=CC=C2N(C)N=NC2=C1 HXQHRUJXQJEGER-UHFFFAOYSA-N 0.000 abstract 1
- DRLUWQXJGGKULE-UHFFFAOYSA-N 3h-1,2$l^{6},3-benzoxathiazole 2,2-dioxide Chemical compound C1=CC=C2OS(=O)(=O)NC2=C1 DRLUWQXJGGKULE-UHFFFAOYSA-N 0.000 abstract 1
- 102000014654 Aromatase Human genes 0.000 abstract 1
- 108010078554 Aromatase Proteins 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 239000002532 enzyme inhibitor Substances 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000002460 imidazoles Chemical class 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D419/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Gynecology & Obstetrics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pregnancy & Childbirth (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03293152A EP1544195A1 (en) | 2003-12-15 | 2003-12-15 | 1-N-phenyl-amino- 1H-imidazole derivatives and pharmaceutical compositions containing them |
| EP04292681 | 2004-11-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR047144A1 true AR047144A1 (es) | 2006-01-11 |
Family
ID=34702365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040104657A AR047144A1 (es) | 2003-12-15 | 2004-12-15 | Derivados de 1-n-fenilamino-1h-imidazol y composiciones farmaceuticas que los contienen |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8476455B2 (enExample) |
| EP (1) | EP1694650A1 (enExample) |
| JP (2) | JP4834557B2 (enExample) |
| KR (1) | KR20060123186A (enExample) |
| CN (1) | CN1890221B (enExample) |
| AR (1) | AR047144A1 (enExample) |
| AU (1) | AU2004299286B2 (enExample) |
| BR (1) | BRPI0417407A (enExample) |
| CA (1) | CA2549603A1 (enExample) |
| IL (1) | IL176077A0 (enExample) |
| MA (1) | MA28286A1 (enExample) |
| MX (1) | MXPA06006837A (enExample) |
| NO (1) | NO20062710L (enExample) |
| NZ (1) | NZ548399A (enExample) |
| OA (1) | OA13336A (enExample) |
| RU (1) | RU2365586C2 (enExample) |
| TW (1) | TW200533668A (enExample) |
| WO (1) | WO2005058842A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0127923D0 (en) | 2001-11-21 | 2002-01-16 | Sterix Ltd | Compound |
| US20090286863A1 (en) * | 2006-07-05 | 2009-11-19 | David Bruge | Sulfamatobenzothiophene derivatives |
| JP2010511640A (ja) * | 2006-12-04 | 2010-04-15 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | スルファマトベンゾチオフェン（ｓｕｌｆａｍａｔｏｂｅｎｚｏｔｈｉｏｐｈｅｎｅ）誘導体 |
| CA2698814A1 (en) | 2007-09-17 | 2009-03-26 | Preglem S.A. | Treatment of oestrogen dependant conditions in pre-menopausal women |
| GB0914767D0 (en) * | 2009-08-24 | 2009-09-30 | Sterix Ltd | Compound |
| DK3386500T3 (da) | 2015-12-09 | 2022-12-12 | Univ Illinois | Benzothiophen-baserede selektive østrogenreceptor ned-regulatorer |
| JP7229162B2 (ja) | 2017-01-06 | 2023-02-27 | ジー１ セラピューティクス， インコーポレイテッド | 癌の治療に対する併用療法 |
| WO2018187414A1 (en) * | 2017-04-05 | 2018-10-11 | The Regents Of The University Of California | Inhibitors of mtor-rictor interactions |
| US20210322386A1 (en) * | 2018-06-11 | 2021-10-21 | Loma Linda University | Methods of delaying and reversing alzheimer's disease progression |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3558625A (en) * | 1968-10-31 | 1971-01-26 | Merck & Co Inc | Pyrazinecarboxyaldehydes and method for their preparation |
| BE757186A (fr) | 1969-10-07 | 1971-04-07 | Bayer Ag | Nouveaux esters d'acides pyridazino-thiono-phosphoriques et-phosphoniques, leur procede de preparation et leur application comme insecticides et acaricides |
| US4166452A (en) * | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4256108A (en) * | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) * | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US4584302A (en) | 1983-09-26 | 1986-04-22 | Mcneilab, Inc. | Methods for the treatment of ventricular dysrhythmia and prevention of ventricular fibrillation |
| US4978672A (en) * | 1986-03-07 | 1990-12-18 | Ciba-Geigy Corporation | Alpha-heterocyclc substituted tolunitriles |
| US4937250A (en) * | 1988-03-07 | 1990-06-26 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| US4749713A (en) * | 1986-03-07 | 1988-06-07 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| US5071861A (en) * | 1986-03-07 | 1991-12-10 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| DE3811574A1 (de) * | 1988-03-31 | 1989-10-19 | Schering Ag | N-substituierte imidazole, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
| EP0641785B1 (en) * | 1991-09-02 | 1999-10-27 | Yamanouchi Pharmaceutical Co. Ltd. | Triazolylated tertiary amine compound or salt thereof |
| JP2500849B2 (ja) * | 1991-09-02 | 1996-05-29 | 山之内製薬株式会社 | トリアゾリル置換３級アミノ化合物又はその塩 |
| GB2273704B (en) * | 1992-12-16 | 1997-01-22 | Orion Yhtymae Oy | Triazolyl diaryl selective aromatase inhibiting compounds |
| AU5121796A (en) | 1995-05-08 | 1996-11-29 | Nippon Chemiphar Co. Ltd. | 2,4-thiazolidinedione or oxazolidinedione derivatives and hy poglycemic agent |
| DE19731328A1 (de) * | 1997-07-22 | 1999-01-28 | Hoechst Ag | Imidazol-Derivate mit Biphenylsulfonylcyanamid-Seitenkette, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
| GB9807779D0 (en) | 1998-04-09 | 1998-06-10 | Ciba Geigy Ag | Organic compounds |
| US6248780B1 (en) | 1998-10-01 | 2001-06-19 | Duquesne University Of The Holy Ghost | Compounds for the treatment of estrogen-dependent illnesses and methods for making and using the same |
| JP4320089B2 (ja) * | 1999-07-06 | 2009-08-26 | あすか製薬株式会社 | フェニルスルファメート誘導体 |
| US6436972B1 (en) | 2000-04-10 | 2002-08-20 | Dalhousie University | Pyridones and their use as modulators of serine hydrolase enzymes |
| WO2002051821A1 (en) | 2000-12-22 | 2002-07-04 | Astrazeneca Ab | Therapeutic compounds |
| DK1370539T3 (da) * | 2001-02-23 | 2012-02-13 | Leuven K U Res & Dev | HIV-inhiberende N-aminoimidazolderivater |
| CN1370533A (zh) | 2001-02-27 | 2002-09-25 | 中国人民解放军军事医学科学院放射医学研究所 | 一类新的苯并噻吩类化合物在防治妇女绝经后综合症和其它与雌激素相关疾病中的用途 |
| US7109193B2 (en) * | 2001-04-12 | 2006-09-19 | Wyeth | Tricyclic diazepines tocolytic oxytocin receptor antagonists |
| CN100473648C (zh) | 2001-11-21 | 2009-04-01 | 斯特里克斯有限公司 | 作为芳香化酶抑制剂的含氨基磺酸酯基的1,2,4-三唑衍生物 |
| GB0127923D0 (en) * | 2001-11-21 | 2002-01-16 | Sterix Ltd | Compound |
| JP2004196795A (ja) * | 2002-12-16 | 2004-07-15 | Wyeth | 外部寄生虫駆除剤としてのｎ−フェニル−３−シクロプロピルピラゾール−４−カルボニトリル |
| US6737433B1 (en) * | 2002-12-16 | 2004-05-18 | Laboratoire Theramex | 1-N-phenylamino-1H-imidazole derivatives as aromatase inhibitors and pharmaceutical compositions containing them |
| MXPA05012300A (es) | 2003-05-16 | 2006-01-30 | Theramex | Derivados de benzotiofeno de sulfamato como inhibidores de sulfatasa esteroidea. |
-
2004
- 2004-12-15 RU RU2006125417/04A patent/RU2365586C2/ru not_active IP Right Cessation
- 2004-12-15 CA CA002549603A patent/CA2549603A1/en not_active Abandoned
- 2004-12-15 OA OA1200600193A patent/OA13336A/en unknown
- 2004-12-15 MX MXPA06006837A patent/MXPA06006837A/es active IP Right Grant
- 2004-12-15 BR BRPI0417407-0A patent/BRPI0417407A/pt not_active IP Right Cessation
- 2004-12-15 AU AU2004299286A patent/AU2004299286B2/en not_active Ceased
- 2004-12-15 WO PCT/EP2004/014847 patent/WO2005058842A1/en not_active Ceased
- 2004-12-15 NZ NZ548399A patent/NZ548399A/en unknown
- 2004-12-15 AR ARP040104657A patent/AR047144A1/es not_active Application Discontinuation
- 2004-12-15 JP JP2006544394A patent/JP4834557B2/ja not_active Expired - Fee Related
- 2004-12-15 TW TW093138979A patent/TW200533668A/zh unknown
- 2004-12-15 EP EP04804432A patent/EP1694650A1/en not_active Withdrawn
- 2004-12-15 CN CN200480036357.XA patent/CN1890221B/zh not_active Expired - Fee Related
- 2004-12-15 KR KR1020067010009A patent/KR20060123186A/ko not_active Ceased
- 2004-12-15 US US10/582,778 patent/US8476455B2/en not_active Expired - Fee Related
-
2006
- 2006-05-31 IL IL176077A patent/IL176077A0/en unknown
- 2006-06-12 NO NO20062710A patent/NO20062710L/no not_active Application Discontinuation
- 2006-07-07 MA MA29173A patent/MA28286A1/fr unknown
-
2011
- 2011-06-21 JP JP2011137461A patent/JP5209760B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NZ548399A (en) | 2011-01-28 |
| NO20062710L (no) | 2006-06-30 |
| CN1890221A (zh) | 2007-01-03 |
| KR20060123186A (ko) | 2006-12-01 |
| AU2004299286A1 (en) | 2005-06-30 |
| MXPA06006837A (es) | 2006-09-04 |
| OA13336A (en) | 2006-04-13 |
| AU2004299286B2 (en) | 2011-06-30 |
| IL176077A0 (en) | 2006-10-05 |
| MA28286A1 (fr) | 2006-11-01 |
| RU2365586C2 (ru) | 2009-08-27 |
| JP2007515420A (ja) | 2007-06-14 |
| BRPI0417407A (pt) | 2007-04-03 |
| RU2006125417A (ru) | 2008-01-27 |
| JP4834557B2 (ja) | 2011-12-14 |
| US20070112009A1 (en) | 2007-05-17 |
| JP5209760B2 (ja) | 2013-06-12 |
| JP2011190277A (ja) | 2011-09-29 |
| WO2005058842A1 (en) | 2005-06-30 |
| US8476455B2 (en) | 2013-07-02 |
| EP1694650A1 (en) | 2006-08-30 |
| TW200533668A (en) | 2005-10-16 |
| CN1890221B (zh) | 2014-07-16 |
| CA2549603A1 (en) | 2005-06-30 |
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