CA2549603A1 - 1-n-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them - Google Patents
1-n-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them Download PDFInfo
- Publication number
- CA2549603A1 CA2549603A1 CA002549603A CA2549603A CA2549603A1 CA 2549603 A1 CA2549603 A1 CA 2549603A1 CA 002549603 A CA002549603 A CA 002549603A CA 2549603 A CA2549603 A CA 2549603A CA 2549603 A1 CA2549603 A1 CA 2549603A1
- Authority
- CA
- Canada
- Prior art keywords
- cndot
- hydroxy
- cyano
- halogen
- derivative according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
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- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D419/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Gynecology & Obstetrics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pregnancy & Childbirth (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03293152.9 | 2003-12-15 | ||
| EP03293152A EP1544195A1 (en) | 2003-12-15 | 2003-12-15 | 1-N-phenyl-amino- 1H-imidazole derivatives and pharmaceutical compositions containing them |
| EP04292681.6 | 2004-11-12 | ||
| EP04292681 | 2004-11-12 | ||
| PCT/EP2004/014847 WO2005058842A1 (en) | 2003-12-15 | 2004-12-15 | 1-n-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2549603A1 true CA2549603A1 (en) | 2005-06-30 |
Family
ID=34702365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002549603A Abandoned CA2549603A1 (en) | 2003-12-15 | 2004-12-15 | 1-n-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8476455B2 (enExample) |
| EP (1) | EP1694650A1 (enExample) |
| JP (2) | JP4834557B2 (enExample) |
| KR (1) | KR20060123186A (enExample) |
| CN (1) | CN1890221B (enExample) |
| AR (1) | AR047144A1 (enExample) |
| AU (1) | AU2004299286B2 (enExample) |
| BR (1) | BRPI0417407A (enExample) |
| CA (1) | CA2549603A1 (enExample) |
| IL (1) | IL176077A0 (enExample) |
| MA (1) | MA28286A1 (enExample) |
| MX (1) | MXPA06006837A (enExample) |
| NO (1) | NO20062710L (enExample) |
| NZ (1) | NZ548399A (enExample) |
| OA (1) | OA13336A (enExample) |
| RU (1) | RU2365586C2 (enExample) |
| TW (1) | TW200533668A (enExample) |
| WO (1) | WO2005058842A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0127923D0 (en) | 2001-11-21 | 2002-01-16 | Sterix Ltd | Compound |
| US20090286863A1 (en) * | 2006-07-05 | 2009-11-19 | David Bruge | Sulfamatobenzothiophene derivatives |
| JP2010511640A (ja) * | 2006-12-04 | 2010-04-15 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | スルファマトベンゾチオフェン（ｓｕｌｆａｍａｔｏｂｅｎｚｏｔｈｉｏｐｈｅｎｅ）誘導体 |
| CA2698814A1 (en) | 2007-09-17 | 2009-03-26 | Preglem S.A. | Treatment of oestrogen dependant conditions in pre-menopausal women |
| GB0914767D0 (en) * | 2009-08-24 | 2009-09-30 | Sterix Ltd | Compound |
| DK3386500T3 (da) | 2015-12-09 | 2022-12-12 | Univ Illinois | Benzothiophen-baserede selektive østrogenreceptor ned-regulatorer |
| JP7229162B2 (ja) | 2017-01-06 | 2023-02-27 | ジー１ セラピューティクス， インコーポレイテッド | 癌の治療に対する併用療法 |
| WO2018187414A1 (en) * | 2017-04-05 | 2018-10-11 | The Regents Of The University Of California | Inhibitors of mtor-rictor interactions |
| US20210322386A1 (en) * | 2018-06-11 | 2021-10-21 | Loma Linda University | Methods of delaying and reversing alzheimer's disease progression |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3558625A (en) * | 1968-10-31 | 1971-01-26 | Merck & Co Inc | Pyrazinecarboxyaldehydes and method for their preparation |
| BE757186A (fr) | 1969-10-07 | 1971-04-07 | Bayer Ag | Nouveaux esters d'acides pyridazino-thiono-phosphoriques et-phosphoniques, leur procede de preparation et leur application comme insecticides et acaricides |
| US4166452A (en) * | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4256108A (en) * | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) * | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US4584302A (en) | 1983-09-26 | 1986-04-22 | Mcneilab, Inc. | Methods for the treatment of ventricular dysrhythmia and prevention of ventricular fibrillation |
| US4978672A (en) * | 1986-03-07 | 1990-12-18 | Ciba-Geigy Corporation | Alpha-heterocyclc substituted tolunitriles |
| US4937250A (en) * | 1988-03-07 | 1990-06-26 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| US4749713A (en) * | 1986-03-07 | 1988-06-07 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| US5071861A (en) * | 1986-03-07 | 1991-12-10 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| DE3811574A1 (de) * | 1988-03-31 | 1989-10-19 | Schering Ag | N-substituierte imidazole, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
| EP0641785B1 (en) * | 1991-09-02 | 1999-10-27 | Yamanouchi Pharmaceutical Co. Ltd. | Triazolylated tertiary amine compound or salt thereof |
| JP2500849B2 (ja) * | 1991-09-02 | 1996-05-29 | 山之内製薬株式会社 | トリアゾリル置換３級アミノ化合物又はその塩 |
| GB2273704B (en) * | 1992-12-16 | 1997-01-22 | Orion Yhtymae Oy | Triazolyl diaryl selective aromatase inhibiting compounds |
| AU5121796A (en) | 1995-05-08 | 1996-11-29 | Nippon Chemiphar Co. Ltd. | 2,4-thiazolidinedione or oxazolidinedione derivatives and hy poglycemic agent |
| DE19731328A1 (de) * | 1997-07-22 | 1999-01-28 | Hoechst Ag | Imidazol-Derivate mit Biphenylsulfonylcyanamid-Seitenkette, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
| GB9807779D0 (en) | 1998-04-09 | 1998-06-10 | Ciba Geigy Ag | Organic compounds |
| US6248780B1 (en) | 1998-10-01 | 2001-06-19 | Duquesne University Of The Holy Ghost | Compounds for the treatment of estrogen-dependent illnesses and methods for making and using the same |
| JP4320089B2 (ja) * | 1999-07-06 | 2009-08-26 | あすか製薬株式会社 | フェニルスルファメート誘導体 |
| US6436972B1 (en) | 2000-04-10 | 2002-08-20 | Dalhousie University | Pyridones and their use as modulators of serine hydrolase enzymes |
| WO2002051821A1 (en) | 2000-12-22 | 2002-07-04 | Astrazeneca Ab | Therapeutic compounds |
| DK1370539T3 (da) * | 2001-02-23 | 2012-02-13 | Leuven K U Res & Dev | HIV-inhiberende N-aminoimidazolderivater |
| CN1370533A (zh) | 2001-02-27 | 2002-09-25 | 中国人民解放军军事医学科学院放射医学研究所 | 一类新的苯并噻吩类化合物在防治妇女绝经后综合症和其它与雌激素相关疾病中的用途 |
| US7109193B2 (en) * | 2001-04-12 | 2006-09-19 | Wyeth | Tricyclic diazepines tocolytic oxytocin receptor antagonists |
| CN100473648C (zh) | 2001-11-21 | 2009-04-01 | 斯特里克斯有限公司 | 作为芳香化酶抑制剂的含氨基磺酸酯基的1,2,4-三唑衍生物 |
| GB0127923D0 (en) * | 2001-11-21 | 2002-01-16 | Sterix Ltd | Compound |
| JP2004196795A (ja) * | 2002-12-16 | 2004-07-15 | Wyeth | 外部寄生虫駆除剤としてのｎ−フェニル−３−シクロプロピルピラゾール−４−カルボニトリル |
| US6737433B1 (en) * | 2002-12-16 | 2004-05-18 | Laboratoire Theramex | 1-N-phenylamino-1H-imidazole derivatives as aromatase inhibitors and pharmaceutical compositions containing them |
| MXPA05012300A (es) | 2003-05-16 | 2006-01-30 | Theramex | Derivados de benzotiofeno de sulfamato como inhibidores de sulfatasa esteroidea. |
-
2004
- 2004-12-15 RU RU2006125417/04A patent/RU2365586C2/ru not_active IP Right Cessation
- 2004-12-15 CA CA002549603A patent/CA2549603A1/en not_active Abandoned
- 2004-12-15 OA OA1200600193A patent/OA13336A/en unknown
- 2004-12-15 MX MXPA06006837A patent/MXPA06006837A/es active IP Right Grant
- 2004-12-15 BR BRPI0417407-0A patent/BRPI0417407A/pt not_active IP Right Cessation
- 2004-12-15 AU AU2004299286A patent/AU2004299286B2/en not_active Ceased
- 2004-12-15 WO PCT/EP2004/014847 patent/WO2005058842A1/en not_active Ceased
- 2004-12-15 NZ NZ548399A patent/NZ548399A/en unknown
- 2004-12-15 AR ARP040104657A patent/AR047144A1/es not_active Application Discontinuation
- 2004-12-15 JP JP2006544394A patent/JP4834557B2/ja not_active Expired - Fee Related
- 2004-12-15 TW TW093138979A patent/TW200533668A/zh unknown
- 2004-12-15 EP EP04804432A patent/EP1694650A1/en not_active Withdrawn
- 2004-12-15 CN CN200480036357.XA patent/CN1890221B/zh not_active Expired - Fee Related
- 2004-12-15 KR KR1020067010009A patent/KR20060123186A/ko not_active Ceased
- 2004-12-15 US US10/582,778 patent/US8476455B2/en not_active Expired - Fee Related
-
2006
- 2006-05-31 IL IL176077A patent/IL176077A0/en unknown
- 2006-06-12 NO NO20062710A patent/NO20062710L/no not_active Application Discontinuation
- 2006-07-07 MA MA29173A patent/MA28286A1/fr unknown
-
2011
- 2011-06-21 JP JP2011137461A patent/JP5209760B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NZ548399A (en) | 2011-01-28 |
| NO20062710L (no) | 2006-06-30 |
| CN1890221A (zh) | 2007-01-03 |
| KR20060123186A (ko) | 2006-12-01 |
| AU2004299286A1 (en) | 2005-06-30 |
| MXPA06006837A (es) | 2006-09-04 |
| OA13336A (en) | 2006-04-13 |
| AU2004299286B2 (en) | 2011-06-30 |
| IL176077A0 (en) | 2006-10-05 |
| MA28286A1 (fr) | 2006-11-01 |
| RU2365586C2 (ru) | 2009-08-27 |
| JP2007515420A (ja) | 2007-06-14 |
| AR047144A1 (es) | 2006-01-11 |
| BRPI0417407A (pt) | 2007-04-03 |
| RU2006125417A (ru) | 2008-01-27 |
| JP4834557B2 (ja) | 2011-12-14 |
| US20070112009A1 (en) | 2007-05-17 |
| JP5209760B2 (ja) | 2013-06-12 |
| JP2011190277A (ja) | 2011-09-29 |
| WO2005058842A1 (en) | 2005-06-30 |
| US8476455B2 (en) | 2013-07-02 |
| EP1694650A1 (en) | 2006-08-30 |
| TW200533668A (en) | 2005-10-16 |
| CN1890221B (zh) | 2014-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20161014 |