AR046553A1 - Derivados de bengamida, procedimiento para su preparacion, y su uso - Google Patents
Derivados de bengamida, procedimiento para su preparacion, y su usoInfo
- Publication number
- AR046553A1 AR046553A1 ARP040103818A ARP040103818A AR046553A1 AR 046553 A1 AR046553 A1 AR 046553A1 AR P040103818 A ARP040103818 A AR P040103818A AR P040103818 A ARP040103818 A AR P040103818A AR 046553 A1 AR046553 A1 AR 046553A1
- Authority
- AR
- Argentina
- Prior art keywords
- bengamide
- procedure
- preparation
- bengamide derivatives
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/08—Oxygen atoms
- C07D223/10—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
La presente se refiere a derivados de bengamida formados, durante la fermentación, por el microorganismo Myxococcus virescens ST200611 (DSM 15898), a su uso para tratar enfermedades oncológicas, a productos farmacéuticos que comprenden derivados de bengamida, a un procedimiento para preparar bengamidas de la fórmula (2), y al microorganismo Myxococcus virescens ST200611 (DSM 15898). Reivindicación 1: Un compuesto de la fórmula (1), en la que R1 es H o alquilo C1-6; R2 es H u OH; y R3 es H o - C(=O)-alquilo C1-6 o una sal fisiológicamente del mismo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10349669A DE10349669B3 (de) | 2003-10-24 | 2003-10-24 | Bengamide-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR046553A1 true AR046553A1 (es) | 2005-12-14 |
Family
ID=34484998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040103818A AR046553A1 (es) | 2003-10-24 | 2004-10-21 | Derivados de bengamida, procedimiento para su preparacion, y su uso |
Country Status (30)
| Country | Link |
|---|---|
| EP (2) | EP1680405B1 (es) |
| JP (1) | JP4769190B2 (es) |
| KR (1) | KR20060120044A (es) |
| CN (2) | CN101294173A (es) |
| AR (1) | AR046553A1 (es) |
| AT (2) | ATE477244T1 (es) |
| AU (1) | AU2004287561B2 (es) |
| BR (1) | BRPI0415529A (es) |
| CA (1) | CA2543003A1 (es) |
| CL (1) | CL2009000674A1 (es) |
| CY (1) | CY1110458T1 (es) |
| DE (3) | DE10349669B3 (es) |
| DK (1) | DK1680405T3 (es) |
| ES (1) | ES2320894T3 (es) |
| HK (1) | HK1098131A1 (es) |
| HR (1) | HRP20090187T1 (es) |
| IL (1) | IL174524A (es) |
| MA (1) | MA28213A1 (es) |
| ME (1) | MEP33108A (es) |
| MX (1) | MXPA06004084A (es) |
| NO (1) | NO20062149L (es) |
| NZ (1) | NZ546744A (es) |
| PL (1) | PL1680405T3 (es) |
| PT (1) | PT1680405E (es) |
| RS (1) | RS20060263A (es) |
| RU (1) | RU2357956C2 (es) |
| SI (1) | SI1680405T1 (es) |
| UY (1) | UY28574A1 (es) |
| WO (1) | WO2005044803A1 (es) |
| ZA (1) | ZA200602231B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2878525B1 (fr) * | 2004-11-29 | 2007-02-23 | Aventis Pharma Sa | Bengamides possedant un cycle caprolactame substitue, procede de preparation, compositions les contenant et utilisation |
| FR2878528B1 (fr) | 2004-11-29 | 2008-05-16 | Aventis Pharma Sa | 2-alcoxy-3,4,5-trihydroxy-alkylamides, leur preparation, compositions les contenant et utilisation |
| FR2901554B1 (fr) | 2006-05-24 | 2011-04-01 | Sanofi Aventis | 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzazepine, leur preparation, compositions les contenant et utilisation |
| FR2901556A1 (fr) | 2006-05-24 | 2007-11-30 | Sanofi Aventis Sa | Derives de 2-alcoxy-3,4,5-trihydroxy-alkylamide, leur preparation, compositions les contenant et utilisation |
| FR2901555A1 (fr) | 2006-05-24 | 2007-11-30 | Sanofi Aventis Sa | 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzothiazepine, leur preparation, compositions les contenant et utilisation |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CO5140099A1 (es) * | 1998-11-17 | 2002-03-22 | Novartis Ag | Ciertas caprolactamas sustituidas, composiciones farmaceuticas que las contienen, y su uso en el tratamiento de tumores |
| EP1282604B1 (en) * | 2000-05-11 | 2008-01-09 | Novartis AG | Substituted caprolactam carbonates and ethers and their use as anti-tumor agents |
| JP2004262793A (ja) * | 2003-02-28 | 2004-09-24 | Noyaku Bio Technology Kaihatsu Gijutsu Kenkyu Kumiai | 化合物ｎ−９０１１、その製造法及び用途 |
| MXPA06000975A (es) * | 2003-07-25 | 2006-04-11 | Novartis Ag | Lactams sustituidos y su uso como agentes anti-cancer. |
-
2003
- 2003-10-24 DE DE10349669A patent/DE10349669B3/de not_active Expired - Fee Related
-
2004
- 2004-10-08 NZ NZ546744A patent/NZ546744A/en unknown
- 2004-10-08 CN CNA2008100958532A patent/CN101294173A/zh active Pending
- 2004-10-08 ES ES04765884T patent/ES2320894T3/es active Active
- 2004-10-08 EP EP04765884A patent/EP1680405B1/de active Active
- 2004-10-08 CA CA002543003A patent/CA2543003A1/en not_active Abandoned
- 2004-10-08 DE DE502004011536T patent/DE502004011536D1/de active Active
- 2004-10-08 PT PT04765884T patent/PT1680405E/pt unknown
- 2004-10-08 DE DE502004008837T patent/DE502004008837D1/de active Active
- 2004-10-08 AU AU2004287561A patent/AU2004287561B2/en not_active Expired - Fee Related
- 2004-10-08 ME MEP-331/08A patent/MEP33108A/xx unknown
- 2004-10-08 WO PCT/EP2004/011244 patent/WO2005044803A1/de active Application Filing
- 2004-10-08 BR BRPI0415529-7A patent/BRPI0415529A/pt not_active IP Right Cessation
- 2004-10-08 MX MXPA06004084A patent/MXPA06004084A/es active IP Right Grant
- 2004-10-08 DK DK04765884T patent/DK1680405T3/da active
- 2004-10-08 AT AT07007021T patent/ATE477244T1/de not_active IP Right Cessation
- 2004-10-08 AT AT04765884T patent/ATE420074T1/de active
- 2004-10-08 RS YUP-2006/0263A patent/RS20060263A/sr unknown
- 2004-10-08 KR KR1020067007889A patent/KR20060120044A/ko not_active Application Discontinuation
- 2004-10-08 SI SI200431054T patent/SI1680405T1/sl unknown
- 2004-10-08 EP EP07007021A patent/EP1873146B1/de active Active
- 2004-10-08 RU RU2006117769/04A patent/RU2357956C2/ru not_active IP Right Cessation
- 2004-10-08 PL PL04765884T patent/PL1680405T3/pl unknown
- 2004-10-08 JP JP2006535987A patent/JP4769190B2/ja not_active Expired - Fee Related
- 2004-10-08 CN CNB2004800306469A patent/CN100398520C/zh not_active Expired - Fee Related
- 2004-10-21 AR ARP040103818A patent/AR046553A1/es not_active Application Discontinuation
- 2004-10-22 UY UY28574A patent/UY28574A1/es unknown
-
2006
- 2006-03-16 ZA ZA200602231A patent/ZA200602231B/en unknown
- 2006-03-23 IL IL174524A patent/IL174524A/en not_active IP Right Cessation
- 2006-04-21 MA MA28955A patent/MA28213A1/fr unknown
- 2006-05-12 NO NO20062149A patent/NO20062149L/no not_active Application Discontinuation
-
2007
- 2007-02-15 HK HK07101845A patent/HK1098131A1/xx not_active IP Right Cessation
-
2009
- 2009-03-19 CL CL2009000674A patent/CL2009000674A1/es unknown
- 2009-03-23 CY CY20091100336T patent/CY1110458T1/el unknown
- 2009-03-31 HR HR20090187T patent/HRP20090187T1/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |