AR045994A1 - Farmaco activo para el dolor neuropatico - Google Patents

Farmaco activo para el dolor neuropatico

Info

Publication number
AR045994A1
AR045994A1 ARP040102487A ARP040102487A AR045994A1 AR 045994 A1 AR045994 A1 AR 045994A1 AR P040102487 A ARP040102487 A AR P040102487A AR P040102487 A ARP040102487 A AR P040102487A AR 045994 A1 AR045994 A1 AR 045994A1
Authority
AR
Argentina
Prior art keywords
neuropathic pain
active
pharmaco
linear
branched
Prior art date
Application number
ARP040102487A
Other languages
English (en)
Inventor
Angelo Guglielmotti
Lorenzo Polenzani
Maria Alessandra Alisi
Nicola Cazzolla
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Publication of AR045994A1 publication Critical patent/AR045994A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)

Abstract

Utilización de un compuesto que presenta la fórmula 1 en la que X es CH o N, y en la que, cuando X es CH, R es H, OH una cadena alquilo lineal o ramificada con C1-3, una cadena alcoxi lineal o ramificada C1-3 o un átomo de halógeno, y en la que, cuando X es N, R es H, o de una sal de adición de ácido con un ácido orgánico o inorgánico farmacéuticamente aceptable, para la preparación de una composición farmacéutica activa para tratar el dolor neuropático
ARP040102487A 2003-07-18 2004-07-15 Farmaco activo para el dolor neuropatico AR045994A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001468A ITMI20031468A1 (it) 2003-07-18 2003-07-18 Farmaco ativo nel dolore neuropatico

Publications (1)

Publication Number Publication Date
AR045994A1 true AR045994A1 (es) 2005-11-23

Family

ID=34131194

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040102487A AR045994A1 (es) 2003-07-18 2004-07-15 Farmaco activo para el dolor neuropatico

Country Status (22)

Country Link
US (1) US7638534B2 (es)
EP (1) EP1646387B1 (es)
JP (1) JP4881729B2 (es)
KR (1) KR101073993B1 (es)
CN (1) CN100427089C (es)
AR (1) AR045994A1 (es)
AT (1) ATE345134T1 (es)
AU (1) AU2004262878B2 (es)
CA (1) CA2526052C (es)
DE (1) DE602004003251T2 (es)
DK (1) DK1646387T3 (es)
EA (1) EA008144B1 (es)
ES (1) ES2275232T3 (es)
GE (1) GEP20084343B (es)
HK (1) HK1087026A1 (es)
IL (1) IL172101A (es)
IT (1) ITMI20031468A1 (es)
MX (1) MXPA06000651A (es)
PL (1) PL1646387T3 (es)
PT (1) PT1646387E (es)
UA (1) UA81051C2 (es)
WO (1) WO2005013989A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20062230A1 (it) * 2006-11-22 2008-05-23 Acraf Composto 2-alchil-indazolico procedimento per preparalo e composizione farmaceutica che lo comprende
UA99927C2 (uk) * 2007-11-12 2012-10-25 Ацьенде Кимике Риуните Анджелини Франческо А.Чи.Р.А.Ф. С.П.А. Медикамент, який є активним при невропатичному болі
KR101646093B1 (ko) 2008-07-29 2016-08-05 아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이 세로토닌 활성을 가진 화합물, 이의 제조 방법 및 이를 포함하는 약학적 조성물

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2116024A1 (en) * 1991-08-20 1993-03-04 Francis David King 5-ht4 receptor antagonists
CZ283619B6 (cs) * 1991-09-12 1998-05-13 Smithkline Beecham P.L.C Použití derivátů kyseliny benzoové pro výrobu farmaceutických prostředků, deriváty kyseliny benzoo vé, způsob jejich výroby a farmaceutické prostředky s jejich obsahem
MA22647A1 (fr) * 1991-09-14 1993-04-01 Smithkline Beecham Plc Procede de preparation d'un ester ou d'un amide d'un nouveau produit .
GB9120628D0 (en) 1991-09-27 1991-11-06 Fujisawa Pharmaceutical Co Pyrrolobenzoxazine derivatives and process for preparation thereof
DE69325167T2 (de) 1992-03-12 2000-01-20 Smithkline Beecham P.L.C., Brentford Kondensierte indol-derivate als 5-ht4-rezeptor-antagonisten
US5864039A (en) * 1994-03-30 1999-01-26 Yoshitomi Pharmaceutical Industries, Ltd. Benzoic acid compounds and use thereof as medicaments
IL117438A (en) * 1995-03-16 2001-12-23 Lilly Co Eli Indazolecarboxamides, their preparation and pharmaceutical compositions containing them
IT1291569B1 (it) * 1997-04-15 1999-01-11 Angelini Ricerche Spa Indazolammidi come agenti serotoninergici
US6069152A (en) * 1997-10-07 2000-05-30 Eli Lilly And Company 5-HT4 agonists and antagonists
DE10132746A1 (de) * 2001-07-05 2003-02-06 Gruenenthal Gmbh Substituierte 1-Phenethylpiperidinverbindungen
US6624162B2 (en) * 2001-10-22 2003-09-23 Pfizer Inc. Imidazopyridine compounds as 5-HT4 receptor modulators
AU2003255767A1 (en) * 2002-08-10 2004-02-25 Astex Technology Limited 3-(carbonyl) 1h-indazole compounds as cyclin dependent kinases (cdk) inhibitors
ITMI20030287A1 (it) * 2003-02-18 2004-08-19 Acraf Indazolammidi dotate di attivita' analgesica metodo, per
ITMI20030972A1 (it) * 2003-05-15 2004-11-16 Acraf Indazolo dotato di attivita' analgesica, metodo per prepararlo e composizione farmaceutica che lo comprende.

Also Published As

Publication number Publication date
AU2004262878B2 (en) 2009-12-17
US7638534B2 (en) 2009-12-29
ES2275232T3 (es) 2007-06-01
WO2005013989A1 (en) 2005-02-17
DE602004003251D1 (de) 2006-12-28
CN1809356A (zh) 2006-07-26
DE602004003251T2 (de) 2007-05-10
PT1646387E (pt) 2007-01-31
DK1646387T3 (da) 2007-03-19
GEP20084343B (en) 2008-03-25
EA008144B1 (ru) 2007-04-27
US20060183775A1 (en) 2006-08-17
PL1646387T3 (pl) 2007-03-30
KR101073993B1 (ko) 2011-10-17
EA200600271A1 (ru) 2006-06-30
CA2526052C (en) 2011-08-30
IL172101A (en) 2011-08-31
JP4881729B2 (ja) 2012-02-22
HK1087026A1 (en) 2006-10-06
EP1646387B1 (en) 2006-11-15
ATE345134T1 (de) 2006-12-15
JP2009513544A (ja) 2009-04-02
AU2004262878A1 (en) 2005-02-17
ITMI20031468A1 (it) 2005-01-19
EP1646387A1 (en) 2006-04-19
IL172101A0 (en) 2009-02-11
CN100427089C (zh) 2008-10-22
UA81051C2 (en) 2007-11-26
KR20060033006A (ko) 2006-04-18
CA2526052A1 (en) 2005-02-17
MXPA06000651A (es) 2006-03-30

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