DE602004003251D1 - Verwendung von indazol-derivaten zur behandlung von neuropathischen schmerzen - Google Patents

Verwendung von indazol-derivaten zur behandlung von neuropathischen schmerzen

Info

Publication number
DE602004003251D1
DE602004003251D1 DE602004003251T DE602004003251T DE602004003251D1 DE 602004003251 D1 DE602004003251 D1 DE 602004003251D1 DE 602004003251 T DE602004003251 T DE 602004003251T DE 602004003251 T DE602004003251 T DE 602004003251T DE 602004003251 D1 DE602004003251 D1 DE 602004003251D1
Authority
DE
Germany
Prior art keywords
treatment
neuropathic pain
indazol
derivatives
indazol derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004003251T
Other languages
English (en)
Other versions
DE602004003251T2 (de
Inventor
Angelo Guglielmotti
Lorenzo Polenzani
Alessandra Alisi
Nicola Cazzolla
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angelini Acraf SpA
Original Assignee
Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aziende Chimiche Riunite Angelini Francesco ACRAF SpA filed Critical Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Publication of DE602004003251D1 publication Critical patent/DE602004003251D1/de
Application granted granted Critical
Publication of DE602004003251T2 publication Critical patent/DE602004003251T2/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE602004003251T 2003-07-18 2004-07-08 Verwendung von indazol-derivaten zur behandlung von neuropathischen schmerzen Active DE602004003251T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI20031468 2003-07-18
IT001468A ITMI20031468A1 (it) 2003-07-18 2003-07-18 Farmaco ativo nel dolore neuropatico
PCT/EP2004/007635 WO2005013989A1 (en) 2003-07-18 2004-07-08 Use of indazole derivatives for the treatment of neuropathic pain

Publications (2)

Publication Number Publication Date
DE602004003251D1 true DE602004003251D1 (de) 2006-12-28
DE602004003251T2 DE602004003251T2 (de) 2007-05-10

Family

ID=34131194

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004003251T Active DE602004003251T2 (de) 2003-07-18 2004-07-08 Verwendung von indazol-derivaten zur behandlung von neuropathischen schmerzen

Country Status (22)

Country Link
US (1) US7638534B2 (de)
EP (1) EP1646387B1 (de)
JP (1) JP4881729B2 (de)
KR (1) KR101073993B1 (de)
CN (1) CN100427089C (de)
AR (1) AR045994A1 (de)
AT (1) ATE345134T1 (de)
AU (1) AU2004262878B2 (de)
CA (1) CA2526052C (de)
DE (1) DE602004003251T2 (de)
DK (1) DK1646387T3 (de)
EA (1) EA008144B1 (de)
ES (1) ES2275232T3 (de)
GE (1) GEP20084343B (de)
HK (1) HK1087026A1 (de)
IL (1) IL172101A (de)
IT (1) ITMI20031468A1 (de)
MX (1) MXPA06000651A (de)
PL (1) PL1646387T3 (de)
PT (1) PT1646387E (de)
UA (1) UA81051C2 (de)
WO (1) WO2005013989A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20062230A1 (it) 2006-11-22 2008-05-23 Acraf Composto 2-alchil-indazolico procedimento per preparalo e composizione farmaceutica che lo comprende
UA99927C2 (uk) * 2007-11-12 2012-10-25 Ацьенде Кимике Риуните Анджелини Франческо А.Чи.Р.А.Ф. С.П.А. Медикамент, який є активним при невропатичному болі
US8686147B2 (en) 2008-07-29 2014-04-01 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Compound with serotoninergic activity, process for preparing it and pharmaceutical composition comprising it

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2435092A (en) 1991-08-20 1993-03-16 Smithkline Beecham Plc 5-ht4 receptor antagonists
CA2118812C (en) * 1991-09-12 2006-01-17 Francis David King 5-ht4 receptor antagonists
MA22647A1 (fr) * 1991-09-14 1993-04-01 Smithkline Beecham Plc Procede de preparation d'un ester ou d'un amide d'un nouveau produit .
GB9120628D0 (en) 1991-09-27 1991-11-06 Fujisawa Pharmaceutical Co Pyrrolobenzoxazine derivatives and process for preparation thereof
MY110110A (en) 1992-03-12 1998-01-27 Smithkline Beecham Plc Pharmaceuticals in the treatment of gastrointestinal disorders, cardiovascular disorders and cns disorders
US5864039A (en) * 1994-03-30 1999-01-26 Yoshitomi Pharmaceutical Industries, Ltd. Benzoic acid compounds and use thereof as medicaments
IL117438A (en) * 1995-03-16 2001-12-23 Lilly Co Eli Indazolecarboxamides, their preparation and pharmaceutical compositions containing them
IT1291569B1 (it) * 1997-04-15 1999-01-11 Angelini Ricerche Spa Indazolammidi come agenti serotoninergici
US6069152A (en) * 1997-10-07 2000-05-30 Eli Lilly And Company 5-HT4 agonists and antagonists
DE10132746A1 (de) * 2001-07-05 2003-02-06 Gruenenthal Gmbh Substituierte 1-Phenethylpiperidinverbindungen
US6624162B2 (en) * 2001-10-22 2003-09-23 Pfizer Inc. Imidazopyridine compounds as 5-HT4 receptor modulators
JP2006502133A (ja) * 2002-08-10 2006-01-19 アステックス、セラピューティックス、リミテッド サイクリン依存キナーゼ（ｃｄｋ）インヒビターとしての３−（カルボニル）１ｈ−インダゾール化合物
ITMI20030287A1 (it) 2003-02-18 2004-08-19 Acraf Indazolammidi dotate di attivita' analgesica metodo, per
ITMI20030972A1 (it) * 2003-05-15 2004-11-16 Acraf Indazolo dotato di attivita' analgesica, metodo per prepararlo e composizione farmaceutica che lo comprende.

Also Published As

Publication number Publication date
EA008144B1 (ru) 2007-04-27
DE602004003251T2 (de) 2007-05-10
IL172101A0 (en) 2009-02-11
PL1646387T3 (pl) 2007-03-30
ES2275232T3 (es) 2007-06-01
DK1646387T3 (da) 2007-03-19
AU2004262878A1 (en) 2005-02-17
ITMI20031468A1 (it) 2005-01-19
EA200600271A1 (ru) 2006-06-30
US7638534B2 (en) 2009-12-29
GEP20084343B (en) 2008-03-25
JP2009513544A (ja) 2009-04-02
KR20060033006A (ko) 2006-04-18
PT1646387E (pt) 2007-01-31
CN1809356A (zh) 2006-07-26
EP1646387A1 (de) 2006-04-19
US20060183775A1 (en) 2006-08-17
CA2526052C (en) 2011-08-30
UA81051C2 (en) 2007-11-26
MXPA06000651A (es) 2006-03-30
CA2526052A1 (en) 2005-02-17
CN100427089C (zh) 2008-10-22
ATE345134T1 (de) 2006-12-15
HK1087026A1 (en) 2006-10-06
WO2005013989A1 (en) 2005-02-17
JP4881729B2 (ja) 2012-02-22
IL172101A (en) 2011-08-31
AU2004262878B2 (en) 2009-12-17
KR101073993B1 (ko) 2011-10-17
EP1646387B1 (de) 2006-11-15
AR045994A1 (es) 2005-11-23

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