AR040034A1 - Pentafluorosulfanilbenzoilguanidinas, procedimiento para su preparacion, su uso como medicamento o compuesto auxiliar de diagnostico, y un medicamento que las comprende - Google Patents
Pentafluorosulfanilbenzoilguanidinas, procedimiento para su preparacion, su uso como medicamento o compuesto auxiliar de diagnostico, y un medicamento que las comprendeInfo
- Publication number
- AR040034A1 AR040034A1 ARP030101716A ARP030101716A AR040034A1 AR 040034 A1 AR040034 A1 AR 040034A1 AR P030101716 A ARP030101716 A AR P030101716A AR P030101716 A ARP030101716 A AR P030101716A AR 040034 A1 AR040034 A1 AR 040034A1
- Authority
- AR
- Argentina
- Prior art keywords
- group
- atoms
- atom
- medicinal
- so2ch3
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Compuestos que son adecuados como medicamentos anti-arrítmicos con un componente cardioprotector para la profilaxis del infarto y el tratamiento del infarto, y para el tratamiento de la angina de pecho. También inhiben preventivamente los procesos patofisiológicos asociados con el desarrollo de danos inducidos por la isquemia, especialmente en la activación de arritmias cardíacas inducidas por la isquemia. Reivindicación 1: Una pentafluorosulfanilbenzoilguanidina de fórmula (1) y / o (2) en las que R1 es un átomo de H, un grupo alquilo que tiene 1, 2, 3, o 4 átomos de C, un grupo alcoxi que tiene 1, 2, 3, o 4 átomos de C un átomo de F, un átomo de Cl, un átomo de Br, un átomo de I, un grupo CN, un grupo NR10R11, un grupo -Op-(CH2)n-(CF2)o-CF3 o un grupo -(Som)q-(CH2)r-(CF2)s-CF3; R10 y R11 son, independientemente uno de otro, un átomo de H, un grupo alquilo que tiene 1,2,3,o 4 átomos de C, o un grupo -CH2-CF3; m es 0,1 o 2; n, o, p, q, r, y s son, independientemente uno de otro, 0, o 1, R2 es un átomo de H, F, Cl, Br, I, un grupo CN, un grupo -SO2CH3, un grupo -(SOh)z-(CH2)k-(CF2)1-CF3, un grupo alquilo que tiene 1, 2, 3, 4, 5 o 6 átomos de C, un grupo cicloalquilo que tiene 3, 4, 5, 6, 7 u 8 átomos de C, en los que 1,2,3 o 4 átomos de H se pueden reemplazar con átomos de F; h es 0, 1 o 2; z es 0 o 1; k es 0, 1, 2, 3, o 4; 1 es 0 o 1; o R2 es un grupo -(CH2)t-fenilo o un grupo -O-fenilo, que está sin sustituir o sustituido con 1, 2, o 3 radicales seleccionados del grupo que consta de un átomo de F, Cl, Br, I, un grupo -Ou-(CH2)v-CF3, un grupo alcoxi que tiene 1, 2, 3, o 4 átomos de C, un grupo alquilo que tiene 1, 2, 3, o 4 átomos de C, y un grupo -SO2CH3; t es 0, 1, 2, 3, o 4; u es 0 o 1; v es 0, 1, 2 o 3; o R2 es un grupo -(CH2)w-heteroarilo, que está sin sustituir o sustituido con 1, 2, o 3 radicales seleccionados del grupo que consta de un átomo de F, Cl, Br, I, un grupo -Ox-(CH2)y-CF3, un grupo alcoxi que tiene 1, 2, 3, o 4 átomos de C, y un grupo alquilo que tiene 1, 2, 3, o 4 átomos de C, y un grupo -SO2CH3; w es 0, 1, 2, 3 o 4; x es 0 o 1; y es 0, 1, 2, o 3; R3 y R4 son, independientemente uno de otro, un átomo de H o F; y sus sales farmacéuticamente aceptables.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10222192A DE10222192A1 (de) | 2002-05-18 | 2002-05-18 | Pentafluorsulfuranyl-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR040034A1 true AR040034A1 (es) | 2005-03-09 |
Family
ID=29285565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030101716A AR040034A1 (es) | 2002-05-18 | 2003-05-16 | Pentafluorosulfanilbenzoilguanidinas, procedimiento para su preparacion, su uso como medicamento o compuesto auxiliar de diagnostico, y un medicamento que las comprende |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP1509498B1 (es) |
| JP (1) | JP4383341B2 (es) |
| KR (1) | KR100977676B1 (es) |
| CN (1) | CN100506791C (es) |
| AR (1) | AR040034A1 (es) |
| AT (1) | ATE343563T1 (es) |
| AU (1) | AU2003242531B2 (es) |
| BR (1) | BR0311128A (es) |
| CA (1) | CA2486336C (es) |
| CY (1) | CY1105867T1 (es) |
| DE (2) | DE10222192A1 (es) |
| DK (1) | DK1509498T3 (es) |
| ES (1) | ES2274264T3 (es) |
| HK (1) | HK1076095A1 (es) |
| HR (1) | HRP20041078B1 (es) |
| IL (2) | IL165213A0 (es) |
| MA (1) | MA27277A1 (es) |
| ME (1) | MEP28908A (es) |
| MX (1) | MXPA04011497A (es) |
| MY (1) | MY139310A (es) |
| NO (1) | NO333288B1 (es) |
| PE (1) | PE20040452A1 (es) |
| PL (1) | PL209700B1 (es) |
| PT (1) | PT1509498E (es) |
| RS (1) | RS50772B (es) |
| RU (1) | RU2315752C2 (es) |
| TW (1) | TWI281467B (es) |
| WO (1) | WO2003097591A1 (es) |
| ZA (1) | ZA200408886B (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7501440B2 (en) | 2003-03-07 | 2009-03-10 | Sanofi-Aventis Deutschland Gmbh | Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use |
| DE10338554A1 (de) * | 2003-08-22 | 2005-03-31 | Aventis Pharma Deutschland Gmbh | Pentafluorosulfanylphenyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE10353204A1 (de) * | 2003-11-13 | 2005-06-16 | Aventis Pharma Deutschland Gmbh | Verfahren zur Herstellung von 4-Pentafluorsulfanyl-benzoylguanidinen |
| OA13285A (en) * | 2003-11-13 | 2007-01-31 | Sanofi Aventis Deutschland | Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same. |
| DE10353205A1 (de) * | 2003-11-13 | 2005-06-16 | Aventis Pharma Deutschland Gmbh | Ortho-substituierte Pentafluorsulfuranyl-Benzole, Verfahren zu ihrer Herstellung sowie ihre Verwendung als wertvolle Synthese-Zwischenstufen |
| DE102004043937A1 (de) * | 2004-09-11 | 2006-03-30 | Sanofi-Aventis Deutschland Gmbh | Ortho-substituierte Pentafluorsulfuranyl-Benzole, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Synthese-Zwischenstufen |
| DE102004043938A1 (de) * | 2004-09-11 | 2006-03-30 | Sanofi-Aventis Deutschland Gmbh | Pentafluorosulfanylphenyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| KR101136251B1 (ko) * | 2007-02-09 | 2012-04-25 | 화이자 리미티드 | 구충제 |
| EP2468722B1 (en) * | 2007-03-23 | 2014-10-01 | UBE Industries, Ltd. | Process for producing arylsulfur halotetrafluorides |
| WO2009028514A1 (ja) * | 2007-08-28 | 2009-03-05 | Ube Industries, Ltd. | ペンタフルオロスルファニルベンゼン化合物の製造方法、及び新規なペンタフルオロスルファニルベンゼン化合物 |
| JP5439745B2 (ja) * | 2008-05-27 | 2014-03-12 | 宇部興産株式会社 | ハロゲノメチルペンタフルオロスルファニルベンゼン化合物及びその製造方法 |
| US9102608B2 (en) | 2011-12-06 | 2015-08-11 | Ube Industries, Ltd. | Method for producing pentafluorosulfanyl benzoic acid |
| CN108003034B (zh) * | 2017-12-26 | 2020-07-03 | 金凯(辽宁)化工有限公司 | 一种2-甲基-5-氨基三氟甲苯的制备方法 |
| RU2765117C2 (ru) * | 2019-09-24 | 2022-01-25 | Федеральное государственное автономное образовательное учреждение высшего образования "Уральский федеральный университет имени первого Президента России Б.Н. Ельцина" | Применение натриевой соли диэтилового эфира 4-оксо-1,4-дигидропиразоло[5,1-с]-1,2,4-триазин-3,8-дикарбоновой кислоты, моногидрата в качестве средства лечения и профилактики поздних осложнений сахарного диабета |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4417004A1 (de) * | 1994-05-13 | 1995-11-16 | Hoechst Ag | Perfluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19517848A1 (de) * | 1995-05-16 | 1996-11-21 | Merck Patent Gmbh | Fluorhaltige Benzoylguanidine |
| DE19526381A1 (de) * | 1995-07-19 | 1997-01-23 | Hoechst Ag | 4-Fluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| GB9606015D0 (en) * | 1996-03-22 | 1996-05-22 | Rhone Poulenc Agriculture | New herbicides |
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2002
- 2002-05-18 DE DE10222192A patent/DE10222192A1/de not_active Withdrawn
-
2003
- 2003-04-25 PE PE2003000415A patent/PE20040452A1/es not_active Application Discontinuation
- 2003-05-05 PT PT03752723T patent/PT1509498E/pt unknown
- 2003-05-05 IL IL16521303A patent/IL165213A0/xx unknown
- 2003-05-05 ME MEP-289/08A patent/MEP28908A/xx unknown
- 2003-05-05 JP JP2004505324A patent/JP4383341B2/ja not_active Expired - Fee Related
- 2003-05-05 MX MXPA04011497A patent/MXPA04011497A/es active IP Right Grant
- 2003-05-05 KR KR1020047018590A patent/KR100977676B1/ko not_active IP Right Cessation
- 2003-05-05 CN CNB038113198A patent/CN100506791C/zh not_active Expired - Fee Related
- 2003-05-05 DK DK03752723T patent/DK1509498T3/da active
- 2003-05-05 CA CA2486336A patent/CA2486336C/en not_active Expired - Fee Related
- 2003-05-05 WO PCT/EP2003/004669 patent/WO2003097591A1/de active IP Right Grant
- 2003-05-05 RU RU2004137115/04A patent/RU2315752C2/ru not_active IP Right Cessation
- 2003-05-05 RS YUP-990/04A patent/RS50772B/sr unknown
- 2003-05-05 DE DE50305498T patent/DE50305498D1/de not_active Expired - Lifetime
- 2003-05-05 EP EP03752723A patent/EP1509498B1/de not_active Expired - Lifetime
- 2003-05-05 AT AT03752723T patent/ATE343563T1/de active
- 2003-05-05 BR BR0311128-8A patent/BR0311128A/pt not_active IP Right Cessation
- 2003-05-05 PL PL371784A patent/PL209700B1/pl unknown
- 2003-05-05 ES ES03752723T patent/ES2274264T3/es not_active Expired - Lifetime
- 2003-05-05 AU AU2003242531A patent/AU2003242531B2/en not_active Ceased
- 2003-05-15 TW TW092113151A patent/TWI281467B/zh not_active IP Right Cessation
- 2003-05-16 MY MYPI20031822A patent/MY139310A/en unknown
- 2003-05-16 AR ARP030101716A patent/AR040034A1/es active IP Right Grant
-
2004
- 2004-11-03 ZA ZA2004/08886A patent/ZA200408886B/en unknown
- 2004-11-15 IL IL165213A patent/IL165213A/en not_active IP Right Cessation
- 2004-11-16 MA MA27949A patent/MA27277A1/fr unknown
- 2004-11-17 HR HRP20041078AA patent/HRP20041078B1/hr not_active IP Right Cessation
- 2004-12-14 NO NO20045447A patent/NO333288B1/no not_active IP Right Cessation
-
2005
- 2005-09-16 HK HK05108117.6A patent/HK1076095A1/xx not_active IP Right Cessation
-
2006
- 2006-12-20 CY CY20061101825T patent/CY1105867T1/el unknown
Also Published As
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