AR035524A1 - Sulfamidotienopirimidinas, un procedimiento para su preparacion, el uso de las mismas para la preparacion de un medicamento, los medicamentos que las comprenden, un conjunto (kit) que las incluye, las preparaciones farmaceuticas que las contienen, y un procedimiento para preparar estas preparaciones - Google Patents
Sulfamidotienopirimidinas, un procedimiento para su preparacion, el uso de las mismas para la preparacion de un medicamento, los medicamentos que las comprenden, un conjunto (kit) que las incluye, las preparaciones farmaceuticas que las contienen, y un procedimiento para preparar estas preparacionesInfo
- Publication number
- AR035524A1 AR035524A1 ARP010105889A ARP010105889A AR035524A1 AR 035524 A1 AR035524 A1 AR 035524A1 AR P010105889 A ARP010105889 A AR P010105889A AR P010105889 A ARP010105889 A AR P010105889A AR 035524 A1 AR035524 A1 AR 035524A1
- Authority
- AR
- Argentina
- Prior art keywords
- formula
- preparation
- compound
- procedure
- hal
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title abstract 3
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 2
- 229940126601 medicinal product Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 2
- ZOOGRGPOEVQQDX-UUOKFMHZSA-N 3',5'-cyclic GMP Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-UUOKFMHZSA-N 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000002993 cycloalkylene group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000012453 solvate Substances 0.000 abstract 2
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
- 101100054666 Streptomyces halstedii sch3 gene Proteins 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- -1 heteroaromatic radical Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002590 phosphodiesterase V inhibitor Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Gynecology & Obstetrics (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10064994A DE10064994A1 (de) | 2000-12-23 | 2000-12-23 | Sulfamidothienopyrimidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR035524A1 true AR035524A1 (es) | 2004-06-02 |
Family
ID=7668967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010105889A AR035524A1 (es) | 2000-12-23 | 2001-12-19 | Sulfamidotienopirimidinas, un procedimiento para su preparacion, el uso de las mismas para la preparacion de un medicamento, los medicamentos que las comprenden, un conjunto (kit) que las incluye, las preparaciones farmaceuticas que las contienen, y un procedimiento para preparar estas preparaciones |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7019013B2 (https=) |
| EP (1) | EP1353927B1 (https=) |
| JP (1) | JP4550361B2 (https=) |
| KR (1) | KR20030062438A (https=) |
| CN (1) | CN1483035A (https=) |
| AR (1) | AR035524A1 (https=) |
| AT (1) | ATE302781T1 (https=) |
| BR (1) | BR0115996A (https=) |
| CA (1) | CA2432582C (https=) |
| CZ (1) | CZ20031815A3 (https=) |
| DE (2) | DE10064994A1 (https=) |
| ES (1) | ES2247007T3 (https=) |
| HU (1) | HUP0302515A3 (https=) |
| MX (1) | MXPA03005714A (https=) |
| PL (1) | PL361733A1 (https=) |
| RU (1) | RU2003122189A (https=) |
| SK (1) | SK8432003A3 (https=) |
| WO (1) | WO2002051848A2 (https=) |
| ZA (1) | ZA200305659B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6849638B2 (en) * | 2001-04-30 | 2005-02-01 | Bayer Pharmaceuticals Corporation | 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same, and their use in the treatment or prevention of pde7b-mediated diseases and conditions |
| EP1847543A1 (de) | 2006-04-19 | 2007-10-24 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen |
| MX2007012313A (es) * | 2006-04-19 | 2007-11-21 | Boehringer Ingelheim Int | Dihidrotienopirimidinas para el tratamiento de enfermedades inflamatorias. |
| WO2008088727A2 (en) | 2007-01-12 | 2008-07-24 | Concert Pharmaceuticals, Inc. | Endothelin receptor antagonists |
| US8080549B2 (en) * | 2007-01-12 | 2011-12-20 | Concert Pharmaceuticals, Inc. | Endothelin receptor antagonists |
| WO2008090114A1 (en) | 2007-01-24 | 2008-07-31 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-) |
| WO2009050236A1 (de) | 2007-10-19 | 2009-04-23 | Boehringer Ingelheim International Gmbh | Neue piperazino-dihydrothienopyrimidin-derivate |
| AU2008313660B2 (en) * | 2007-10-19 | 2013-11-07 | Boehringer Ingelheim International Gmbh | Substituted piperidino-dihydrothienopyrimidines |
| EP2205609B1 (de) | 2007-10-19 | 2017-03-29 | Boehringer Ingelheim International GmbH | Heterocyclus-substituierte piperazino-dihydrothienopyrimidine |
| AU2011281015B2 (en) | 2010-07-23 | 2015-09-24 | President And Fellows Of Harvard College | Tricyclic proteasome activity enhancing compounds |
| US20130059866A1 (en) | 2011-08-24 | 2013-03-07 | Boehringer Ingelheim International Gmbh | Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma |
| US9802954B2 (en) | 2011-08-24 | 2017-10-31 | Boehringer Ingelheim International Gmbh | Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma |
| CA2861464C (en) | 2012-01-25 | 2018-03-06 | Proteostasis Therapeutics, Inc. | Proteasome activity modulating tricyclic compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19644228A1 (de) * | 1996-10-24 | 1998-04-30 | Merck Patent Gmbh | Thienopyrimidine |
| DE19752952A1 (de) * | 1997-11-28 | 1999-06-02 | Merck Patent Gmbh | Thienopyrimidine |
| DE19819023A1 (de) * | 1998-04-29 | 1999-11-04 | Merck Patent Gmbh | Thienopyrimidine |
| EP1167367A4 (en) | 1999-03-30 | 2002-04-24 | Nippon Soda Co | THIENOPYRIMIDINE COMPOUNDS AND SALTS THEREOF, AND PROCESS FOR THE PREPARATION THEREOF |
-
2000
- 2000-12-23 DE DE10064994A patent/DE10064994A1/de not_active Withdrawn
-
2001
- 2001-12-03 MX MXPA03005714A patent/MXPA03005714A/es not_active Application Discontinuation
- 2001-12-03 EP EP01271992A patent/EP1353927B1/de not_active Expired - Lifetime
- 2001-12-03 WO PCT/EP2001/014102 patent/WO2002051848A2/de not_active Ceased
- 2001-12-03 AT AT01271992T patent/ATE302781T1/de not_active IP Right Cessation
- 2001-12-03 ES ES01271992T patent/ES2247007T3/es not_active Expired - Lifetime
- 2001-12-03 US US10/451,183 patent/US7019013B2/en not_active Expired - Fee Related
- 2001-12-03 SK SK843-2003A patent/SK8432003A3/sk unknown
- 2001-12-03 CZ CZ20031815A patent/CZ20031815A3/cs unknown
- 2001-12-03 CA CA2432582A patent/CA2432582C/en not_active Expired - Fee Related
- 2001-12-03 HU HU0302515A patent/HUP0302515A3/hu unknown
- 2001-12-03 BR BR0115996-8A patent/BR0115996A/pt not_active Application Discontinuation
- 2001-12-03 KR KR10-2003-7008265A patent/KR20030062438A/ko not_active Withdrawn
- 2001-12-03 DE DE50107230T patent/DE50107230D1/de not_active Expired - Lifetime
- 2001-12-03 RU RU2003122189/04A patent/RU2003122189A/ru not_active Application Discontinuation
- 2001-12-03 CN CNA018212190A patent/CN1483035A/zh active Pending
- 2001-12-03 PL PL01361733A patent/PL361733A1/xx unknown
- 2001-12-03 JP JP2002552942A patent/JP4550361B2/ja not_active Expired - Fee Related
- 2001-12-19 AR ARP010105889A patent/AR035524A1/es not_active Application Discontinuation
-
2003
- 2003-07-22 ZA ZA200305659A patent/ZA200305659B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1353927A2 (de) | 2003-10-22 |
| DE50107230D1 (de) | 2005-09-29 |
| WO2002051848A2 (de) | 2002-07-04 |
| US7019013B2 (en) | 2006-03-28 |
| BR0115996A (pt) | 2004-01-06 |
| JP2004516329A (ja) | 2004-06-03 |
| HUP0302515A2 (hu) | 2003-11-28 |
| MXPA03005714A (es) | 2003-10-06 |
| CA2432582C (en) | 2011-01-25 |
| ES2247007T3 (es) | 2006-03-01 |
| PL361733A1 (en) | 2004-10-04 |
| EP1353927B1 (de) | 2005-08-24 |
| RU2003122189A (ru) | 2004-12-27 |
| CZ20031815A3 (cs) | 2003-10-15 |
| WO2002051848A3 (de) | 2002-10-24 |
| HUP0302515A3 (en) | 2005-06-28 |
| US20040063943A1 (en) | 2004-04-01 |
| KR20030062438A (ko) | 2003-07-25 |
| JP4550361B2 (ja) | 2010-09-22 |
| ZA200305659B (en) | 2004-08-27 |
| ATE302781T1 (de) | 2005-09-15 |
| DE10064994A1 (de) | 2002-07-04 |
| CA2432582A1 (en) | 2002-07-04 |
| SK8432003A3 (en) | 2003-10-07 |
| CN1483035A (zh) | 2004-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal | ||
| FC | Refusal |