AR023571A1 - Procedimiento para preparar un compuesto aromatico sustituido con un nitrilo terciario - Google Patents

Procedimiento para preparar un compuesto aromatico sustituido con un nitrilo terciario

Info

Publication number
AR023571A1
AR023571A1 ARP000101874A ARP000101874A AR023571A1 AR 023571 A1 AR023571 A1 AR 023571A1 AR P000101874 A ARP000101874 A AR P000101874A AR P000101874 A ARP000101874 A AR P000101874A AR 023571 A1 AR023571 A1 AR 023571A1
Authority
AR
Argentina
Prior art keywords
aromatic compound
formula
nitrile
approximately
tertiary nitrile
Prior art date
Application number
ARP000101874A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR023571A1 publication Critical patent/AR023571A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C3/00—Special supporting arrangements for lens assemblies or monocles
    • G02C3/003—Arrangements for fitting and securing to the head in the position of use
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Optics & Photonics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Se describe un procedimiento para preparar un compuesto aromático sustituido con un nitrilo terciario de formula (1) que comprende tratar un compuestoaromático sustituido de formula (2) con un nitrilo secundario de formula (3) en la presencia de unabase que tiene un valor numérico de pKa en el margencomprendido entre aproximadamente 17 y aproximadamente 30, con la condicion de que la diferencia entre los valores numéricos de pKa de dicha base y delcorrespondiente nitrilo terciario de formula(3 ) no ha de ser mayor que aproximadamente6: en el seno de un disolvente aprotico que tiene una constantedieléctrica (E) de menos de aproximadamente 20: y a una termperatura de reaccion comprendida en el margen de aproximadamente 0sC aaproximadamente 120sC; conlo que se forma dicho producto final del tipo de compuesto aromático sustituido con nitrilo terciario de formula (1) en la que las partes constituyentes W1. W2W3, W4 y W5; y los restos sustituyentes R1. R2, R3, R4, R5, R6 yR7 en los compu estos de Formulas (1)(2)(3) se seleccionan entre grupos y radicales orgánicosconocidos como los que se detallan adicionalmente en la presente memoria descriptiva.
ARP000101874A 1999-04-20 2000-04-19 Procedimiento para preparar un compuesto aromatico sustituido con un nitrilo terciario AR023571A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13017599P 1999-04-20 1999-04-20

Publications (1)

Publication Number Publication Date
AR023571A1 true AR023571A1 (es) 2002-09-04

Family

ID=22443407

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000101874A AR023571A1 (es) 1999-04-20 2000-04-19 Procedimiento para preparar un compuesto aromatico sustituido con un nitrilo terciario

Country Status (24)

Country Link
US (1) US6303782B1 (es)
EP (1) EP1046635B1 (es)
JP (1) JP3420553B2 (es)
KR (1) KR100352111B1 (es)
CN (1) CN1138756C (es)
AR (1) AR023571A1 (es)
AT (1) ATE286019T1 (es)
AU (1) AU771854B2 (es)
BR (1) BR0001628A (es)
CA (1) CA2306004C (es)
DE (1) DE60017001T2 (es)
DK (1) DK1046635T3 (es)
ES (1) ES2233286T3 (es)
HK (1) HK1032041A1 (es)
HU (1) HUP0001613A3 (es)
ID (1) ID25689A (es)
IL (1) IL135633A (es)
PL (1) PL339832A1 (es)
PT (1) PT1046635E (es)
RU (1) RU2182572C2 (es)
TR (1) TR200001053A2 (es)
TW (1) TW552256B (es)
YU (1) YU19700A (es)
ZA (1) ZA200001962B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040186310A1 (en) * 2001-06-22 2004-09-23 Kim Keun-Sik Process for preparation of cyclohexanol derivatives
TW200716517A (en) * 2005-04-29 2007-05-01 Wyeth Corp Process for preparing 3,3-disubstituted oxindoles and thio-oxindoles
CN101486676B (zh) * 2008-12-23 2010-12-08 南京航空航天大学 氰甲基吡啶化合物的制备方法
CN102911080B (zh) * 2012-09-12 2015-01-21 衢州学院 一种制备2,6-二氯-α-(4-氯苯基)-4-硝基苯乙腈的方法
WO2016116555A1 (en) 2015-01-22 2016-07-28 Sanofi-Aventis Deutschland Gmbh Process for the production of 2-[4-(cyclopropanecarbonyl)phenyl]-2-methyl-propanenitrile
CN107114183B (zh) * 2017-05-03 2019-11-19 滨州学院 一种提高冬枣果实品质的土壤管理方法

Also Published As

Publication number Publication date
BR0001628A (pt) 2001-01-02
DE60017001D1 (de) 2005-02-03
KR100352111B1 (ko) 2002-09-12
TW552256B (en) 2003-09-11
HUP0001613A2 (hu) 2000-11-28
EP1046635A1 (en) 2000-10-25
HUP0001613A3 (en) 2003-03-28
CN1138756C (zh) 2004-02-18
IL135633A (en) 2005-09-25
JP2000344725A (ja) 2000-12-12
AU2644900A (en) 2000-10-26
ZA200001962B (en) 2002-03-20
ES2233286T3 (es) 2005-06-16
PL339832A1 (en) 2000-10-23
EP1046635B1 (en) 2004-12-29
KR20000071731A (ko) 2000-11-25
TR200001053A2 (tr) 2001-01-22
DE60017001T2 (de) 2005-12-15
ATE286019T1 (de) 2005-01-15
HK1032041A1 (en) 2001-07-06
US6303782B1 (en) 2001-10-16
CA2306004A1 (en) 2000-10-20
CA2306004C (en) 2005-11-29
RU2182572C2 (ru) 2002-05-20
HU0001613D0 (en) 2000-06-28
IL135633A0 (en) 2001-05-20
PT1046635E (pt) 2005-04-29
DK1046635T3 (da) 2005-03-14
YU19700A (sh) 2003-01-31
CN1271723A (zh) 2000-11-01
AU771854B2 (en) 2004-04-01
ID25689A (id) 2000-10-26
JP3420553B2 (ja) 2003-06-23

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