AR019477A1 - Triazolopiridinas para el tratamiento de los trastornos de la trombosis - Google Patents
Triazolopiridinas para el tratamiento de los trastornos de la trombosisInfo
- Publication number
- AR019477A1 AR019477A1 ARP990103671A ARP990103671A AR019477A1 AR 019477 A1 AR019477 A1 AR 019477A1 AR P990103671 A ARP990103671 A AR P990103671A AR P990103671 A ARP990103671 A AR P990103671A AR 019477 A1 AR019477 A1 AR 019477A1
- Authority
- AR
- Argentina
- Prior art keywords
- treatment
- triazolopiridins
- gpiib
- methods
- thrombosis disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Abstract
La invencion se dirige a nuevos derivados de triazolopiridina que resultan de utilidad como antagonistas de la GPIIb/IIIa. También se revelan lascomposiciones farmacéuticas que comprenden los derivados de triazolopiridina de la presente invencion, los métodos para el tratamiento de las condicionesmediadas por la GPIIb/IIIa (por ejemplo, los métodos destinados al tratamiento de los trastornos tromboticos mediados por las plaquetas), junto con losprocesos de fabricacion de los compuestos y los nuevos intermediarios.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9423198P | 1998-07-27 | 1998-07-27 | |
US09/354,032 US6303625B1 (en) | 1998-07-27 | 1999-07-15 | Triazolopyridines for the treatment of thrombosis disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
AR019477A1 true AR019477A1 (es) | 2002-02-20 |
Family
ID=22243910
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990103671A AR019477A1 (es) | 1998-07-27 | 1999-07-26 | Triazolopiridinas para el tratamiento de los trastornos de la trombosis |
Country Status (21)
Country | Link |
---|---|
US (1) | US6303625B1 (es) |
EP (1) | EP1102766B1 (es) |
JP (1) | JP2003527306A (es) |
KR (1) | KR20010079576A (es) |
CN (1) | CN1320125A (es) |
AR (1) | AR019477A1 (es) |
AT (1) | ATE263169T1 (es) |
AU (1) | AU757512B2 (es) |
BR (1) | BR9912556A (es) |
CA (1) | CA2338654A1 (es) |
CZ (1) | CZ2001347A3 (es) |
DE (1) | DE69916073T2 (es) |
ES (1) | ES2219042T3 (es) |
HU (1) | HUP0103832A3 (es) |
ID (1) | ID27214A (es) |
MX (1) | MXPA01001099A (es) |
NO (1) | NO20010456L (es) |
PL (1) | PL345769A1 (es) |
SK (1) | SK1342001A3 (es) |
WO (1) | WO2000006570A1 (es) |
ZA (1) | ZA200100783B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6306909B1 (en) | 1997-03-12 | 2001-10-23 | Queen's University At Kingston | Anti-epileptogenic agents |
CZ2002518A3 (cs) * | 1999-08-13 | 2002-05-15 | Biogen, Inc. | Inhibitory buněčné adheze a farmaceutické prostředky, které je obsahují |
TWI290136B (en) * | 2000-04-05 | 2007-11-21 | Daiichi Seiyaku Co | Ethylenediamine derivatives |
JP2004536071A (ja) * | 2001-05-25 | 2004-12-02 | クイーンズ ユニバーシティ アット キングストン | 複素環ベータアミノ酸およびそれらの抗癲癇誘発剤としての使用 |
WO2003000657A1 (fr) | 2001-06-20 | 2003-01-03 | Daiichi Pharmaceutical Co., Ltd. | Derives de diamine |
WO2006018727A2 (en) * | 2004-08-18 | 2006-02-23 | Pharmacia & Upjohn Company Llc | Triazolopyridine compounds useful for the treatment of inflammation |
US7618983B2 (en) * | 2004-11-10 | 2009-11-17 | Janssen Pharmaceutica, N.V. | Bicyclic triazole α4 integrin inhibitors |
HUE029336T2 (en) * | 2005-09-16 | 2017-02-28 | Daiichi Sankyo Co Ltd | For the preparation of an optically active diamine derivative and process |
WO2008045393A2 (en) * | 2006-10-11 | 2008-04-17 | Amgen Inc. | Imidazo- and triazolo-pyridine compounds and methods of use therof |
EP2417135A1 (en) * | 2009-04-07 | 2012-02-15 | Schering Corporation | Substituted triazolopyridines and analogs thereof |
US8871760B2 (en) * | 2009-09-21 | 2014-10-28 | Roche Palo Alto Llc | [1,2,4]triazolo[3,4-C][1,4]oxazines as P2X7 modulators |
MX339302B (es) | 2011-09-15 | 2016-05-19 | Novartis Ag | 3-(quinolin-6-il-tio)-[1,2,4]-triazolo-[4,3-a]-piridinas 6-sustituidas como cinasas de tirosina. |
EP3004095A1 (de) * | 2013-06-03 | 2016-04-13 | Bayer Pharma Aktiengesellschaft | Triazolopyridine als thrombininhibitoren zur behandlung von thromboembolischen erkrankungen |
GB201511382D0 (en) | 2015-06-29 | 2015-08-12 | Imp Innovations Ltd | Novel compounds and their use in therapy |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3050525A (en) | 1960-12-14 | 1962-08-21 | John B Bicking | Certain derivatives of s-triazolo [4, 3-a]-pyridine |
NZ262664A (en) | 1993-02-22 | 1997-04-24 | Merck & Co Inc | Heterocyclic substituted derivatives, and medicaments thereof |
DE4326758A1 (de) * | 1993-08-10 | 1995-02-16 | Basf Ag | [1,3,4]Triazolo[1,5-a]pyridine |
CA2134192A1 (en) | 1993-11-12 | 1995-05-13 | Michael L. Denney | 5, 6-bicyclic glycoprotein iib/iiia antagonists |
-
1999
- 1999-07-15 US US09/354,032 patent/US6303625B1/en not_active Expired - Lifetime
- 1999-07-21 CA CA002338654A patent/CA2338654A1/en not_active Abandoned
- 1999-07-21 KR KR1020017001183A patent/KR20010079576A/ko not_active Application Discontinuation
- 1999-07-21 HU HU0103832A patent/HUP0103832A3/hu unknown
- 1999-07-21 BR BR9912556-0A patent/BR9912556A/pt not_active Application Discontinuation
- 1999-07-21 AT AT99937373T patent/ATE263169T1/de not_active IP Right Cessation
- 1999-07-21 ES ES99937373T patent/ES2219042T3/es not_active Expired - Lifetime
- 1999-07-21 SK SK134-2001A patent/SK1342001A3/sk unknown
- 1999-07-21 AU AU52218/99A patent/AU757512B2/en not_active Ceased
- 1999-07-21 CN CN99811380A patent/CN1320125A/zh active Pending
- 1999-07-21 JP JP2000562372A patent/JP2003527306A/ja active Pending
- 1999-07-21 WO PCT/US1999/016572 patent/WO2000006570A1/en not_active Application Discontinuation
- 1999-07-21 PL PL99345769A patent/PL345769A1/xx not_active Application Discontinuation
- 1999-07-21 DE DE69916073T patent/DE69916073T2/de not_active Expired - Fee Related
- 1999-07-21 CZ CZ2001347A patent/CZ2001347A3/cs unknown
- 1999-07-21 EP EP99937373A patent/EP1102766B1/en not_active Expired - Lifetime
- 1999-07-21 ID IDW20010365A patent/ID27214A/id unknown
- 1999-07-21 MX MXPA01001099A patent/MXPA01001099A/es unknown
- 1999-07-26 AR ARP990103671A patent/AR019477A1/es unknown
-
2001
- 2001-01-26 NO NO20010456A patent/NO20010456L/no not_active Application Discontinuation
- 2001-01-26 ZA ZA200100783A patent/ZA200100783B/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2003527306A (ja) | 2003-09-16 |
EP1102766A1 (en) | 2001-05-30 |
WO2000006570A1 (en) | 2000-02-10 |
ES2219042T3 (es) | 2004-11-16 |
AU5221899A (en) | 2000-02-21 |
PL345769A1 (en) | 2002-01-02 |
HUP0103832A3 (en) | 2002-12-28 |
CZ2001347A3 (cs) | 2001-12-12 |
HUP0103832A2 (hu) | 2002-04-29 |
US6303625B1 (en) | 2001-10-16 |
ZA200100783B (en) | 2002-01-28 |
NO20010456D0 (no) | 2001-01-26 |
SK1342001A3 (en) | 2002-04-04 |
ID27214A (id) | 2001-03-08 |
DE69916073D1 (de) | 2004-05-06 |
NO20010456L (no) | 2001-03-26 |
CN1320125A (zh) | 2001-10-31 |
DE69916073T2 (de) | 2004-12-30 |
CA2338654A1 (en) | 2000-02-10 |
AU757512B2 (en) | 2003-02-20 |
ATE263169T1 (de) | 2004-04-15 |
MXPA01001099A (es) | 2002-04-24 |
EP1102766B1 (en) | 2004-03-31 |
KR20010079576A (ko) | 2001-08-22 |
BR9912556A (pt) | 2002-01-15 |
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Legal Events
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FB | Suspension of granting procedure |