AR016651A1 - Derivados de 3,4-dihidro-2h-1-benzopirano substituidos con piperidinilo o piperazinilo, proceso para su preparacion, compuestos para su exclusivo uso endicho proceso, formulaciones farmaceuticas que comprenden dichos derivados y su uso para la elaboracion de un medicamento - Google Patents
Derivados de 3,4-dihidro-2h-1-benzopirano substituidos con piperidinilo o piperazinilo, proceso para su preparacion, compuestos para su exclusivo uso endicho proceso, formulaciones farmaceuticas que comprenden dichos derivados y su uso para la elaboracion de un medicamentoInfo
- Publication number
- AR016651A1 AR016651A1 ARP980104637A ARP980104637A AR016651A1 AR 016651 A1 AR016651 A1 AR 016651A1 AR P980104637 A ARP980104637 A AR P980104637A AR P980104637 A ARP980104637 A AR P980104637A AR 016651 A1 AR016651 A1 AR 016651A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- cycloalkyl
- phenyl
- derivatives
- ocf3
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Derivados de 3,4-dihidro-2H-1-benzopirano sustituido con piperidinilo o piperazinilo que tienen la formula (I) en la cual: X es N o CH; Y es NR2CH2,CH2NR2, NR2CO, CONR2, o NR2SO2, donde R2 es H o alquilo C1-6; R1 es H, alquilo C1-6 o cicloalquilo C3-6; R3 es alquilo C1-6, cicloalquilo C3-6 o (CH2)n-arilo,donde arilo es fenilo o un anillo heteroaromático que contiene uno o dos heteroátomos seleccionados entre N, O y S y que puede ser mono- o disustituido con R4y/o R5; donde R4 es H, alquilo C1-6o cicloalquilo C3-6, halogeno, CN, CF3, OH, alcoxi C1-6, NR6R7, OCF3, SO3CH3, SO3CF3, SO2NR6R7, fenilo, fenil-alquilo C1-6,fenoxi, alquilfenilo C1-6, un anillo heterocíclico o heteroaromático optativamente sustituido que contiene uno o dos heteroátomos seleccionados entre N, O, S,SO y SO2, donde el o los sustituyentes es/son seleccionados entre alquilo C1-6, cicloalquilo C3-6 y fenil-alquilo C1-6 o COR6; donde R6 es H, alquilo C1-6 ocicloalquilo C3-6; R7 es H, alquilo C1-6 o cicloalquilo C3-6; R8 es alquilo C1-6 o cicloalquilo C3-6, CF3, OCF3, NR6R7, fenilo o un anillo heterocíclico quecontiene uno o dos heteroátomos seleccionados entre N, O, S, SO y SO2; R5 es H, OH, CF3, OCF3, halogeno, alquilo C1-6 o alcoxi C1-6; n es 0-4; y R9 es alquiloC1-6, cicloalquilo C3-6, OCF3, OCHF2, OCH2F, halogeno, CONR6R7, CN, CF3, OH, alcoxi C1-6, NR6R7, SO3CH3, SO3CF3, SO2NR6R7, un anillo heterocíclico oheteoaromático sustituido o no sustituido que contiene uno o dos heteroátomos seleccionados entre Ny O, donde el o los sustituyentes son alquilo C1-6 o COR8;donde R6, R7 y R8 son como se definieran anteriormente; como enantiomeros (R)-, enantiomeros (S)- o un racemato en forma de base libre o solvatofarmacéuticamente aceptable de los mismos, con un proceso para su preparacion, compuestos para su exclusivo uso en dicho proceso, formulaciones farmacéuticasque contienen dichos compuestos terapéuticamente activos y el uso de dichos compuestos activos para la elaboracion de un medicamento.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9703378A SE9703378D0 (sv) | 1997-09-18 | 1997-09-18 | New compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR016651A1 true AR016651A1 (es) | 2001-07-25 |
Family
ID=20408298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980104637A AR016651A1 (es) | 1997-09-18 | 1998-09-17 | Derivados de 3,4-dihidro-2h-1-benzopirano substituidos con piperidinilo o piperazinilo, proceso para su preparacion, compuestos para su exclusivo uso endicho proceso, formulaciones farmaceuticas que comprenden dichos derivados y su uso para la elaboracion de un medicamento |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US6387899B1 (es) |
| EP (1) | EP1025096B1 (es) |
| JP (1) | JP4002392B2 (es) |
| KR (1) | KR20010024078A (es) |
| CN (1) | CN1278809A (es) |
| AR (1) | AR016651A1 (es) |
| AT (1) | ATE255099T1 (es) |
| AU (1) | AU9193398A (es) |
| BR (1) | BR9812239A (es) |
| CA (1) | CA2303926A1 (es) |
| DE (1) | DE69820103T2 (es) |
| EE (1) | EE200000144A (es) |
| HR (1) | HRP20000133A2 (es) |
| HU (1) | HUP0100276A3 (es) |
| IL (1) | IL135074A0 (es) |
| IS (1) | IS5403A (es) |
| NO (1) | NO20001403L (es) |
| PL (1) | PL339661A1 (es) |
| SE (1) | SE9703378D0 (es) |
| SK (1) | SK2872000A3 (es) |
| TR (1) | TR200000737T2 (es) |
| WO (1) | WO1999014213A1 (es) |
| ZA (1) | ZA987806B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9703377D0 (sv) * | 1997-09-18 | 1997-09-18 | Astra Ab | New compounds |
| IL156595A0 (en) | 2001-01-16 | 2004-01-04 | Astrazeneca Ab | Therapeutic heterocyclic compounds |
| BR0206513A (pt) | 2001-01-16 | 2004-01-06 | Astrazeneca Ab | Composição, métodos de tratamento de um ser humano ou animal que sofre de depressão, ansiedade generalizada, distúrbios da alimentação, demência, distúrbio do p nico, distúrbios do sono, distúrbios gastrointestinais, distúrbios motores, distúrbios endócrinos, vasoespasmo e disfunção sexual, uso de qualquer um dos compostos, composição farmacêutica, e, processo para preparar compostos |
| BR0206514A (pt) * | 2001-01-16 | 2004-01-06 | Astrazeneca Ab | Composto, método de tratamento de um ser humano ou animal que sofre de enxaqueca, uso do composto, composição farmacêutica, e, processo para preparar um composto |
| WO2002066454A1 (en) * | 2001-02-21 | 2002-08-29 | Sankyo Company, Limited | Chromene derivatives |
| JP5080716B2 (ja) * | 2001-07-20 | 2012-11-21 | サイコジェニックス・インコーポレーテッド | 注意欠陥・多動性障害の治療 |
| GB0124020D0 (en) * | 2001-10-05 | 2001-11-28 | Astrazeneca Ab | Chemical compounds |
| ITTO20030140U1 (it) * | 2003-09-16 | 2005-03-17 | Interfila Srl | Matita cosmetica |
| US20050065099A1 (en) * | 2003-09-19 | 2005-03-24 | Gail Walkinshaw | Treatment of mitochondrial diseases |
| US20050165025A1 (en) * | 2004-01-22 | 2005-07-28 | Recordati Ireland Ltd. | Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists |
| TWI346109B (en) * | 2004-04-30 | 2011-08-01 | Otsuka Pharma Co Ltd | 4-amino-5-cyanopyrimidine derivatives |
| KR100681453B1 (ko) * | 2005-03-22 | 2007-02-12 | 태남자동화기기 주식회사 | 권종 분류 기능을 구비한 지폐 방출기 |
| US9066903B2 (en) | 2006-02-28 | 2015-06-30 | The United States Of America As Represented By The Department Of Veterans Affairs | Pharmacological treatment of Parkinson's disease |
| WO2008130321A2 (en) * | 2007-04-23 | 2008-10-30 | Astrazeneca Ab | Novel n-tetrahydronaphtalene or 5-heterocyclyl-chromane or 8-heterocyclyl-tetrahydronaphtalene derivatives for the treatment of pain |
| SA08290245B1 (ar) * | 2007-04-23 | 2012-02-12 | استرازينيكا ايه بي | مشتقات كربو كساميد جديدة من -n (8-اريل رباعي هيدرو نفثالين غير متجانس- 2- يل) أو -n (5-اريل كرومان غير متجانس -3-يل) لعلاج الألم |
| WO2008130322A1 (en) * | 2007-04-23 | 2008-10-30 | Astrazeneca Ab | Novel 5-heterocyclyl-chromane derivatives for the treatment of pain |
| WO2008130323A1 (en) * | 2007-04-23 | 2008-10-30 | Astrazeneca Ab | Novel 8-piperazine-tetrahydronaphtalene derivatives for the treatment of pain |
| WO2008130319A2 (en) * | 2007-04-23 | 2008-10-30 | Astrazeneca Ab | Novel n-tetrahydronaphtalene or n-chromane carboxamide derivatives for the treatment of pain |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04504721A (ja) | 1989-04-27 | 1992-08-20 | ジ・アップジョン・カンパニー | 置換３―アミノ・クロマン類 |
| US5420151A (en) * | 1989-12-22 | 1995-05-30 | Aktiebolaget Astra | Chroman derivatives |
| SE8904361D0 (sv) * | 1989-12-22 | 1989-12-22 | Astra Ab | New chroman and thiochroman derivatives |
| US5972935A (en) | 1995-08-11 | 1999-10-26 | Smithkline Beecham P.L.C. | Biphenyl(thio)amide and bipennylethan(thi) one derivatives, their preparation and their use as 5-HT1D receptor antagonists |
-
1997
- 1997-09-18 SE SE9703378A patent/SE9703378D0/xx unknown
-
1998
- 1998-08-27 ZA ZA987806A patent/ZA987806B/xx unknown
- 1998-09-09 TR TR2000/00737T patent/TR200000737T2/xx unknown
- 1998-09-09 WO PCT/SE1998/001604 patent/WO1999014213A1/en active IP Right Grant
- 1998-09-09 EE EEP200000144A patent/EE200000144A/xx unknown
- 1998-09-09 CA CA002303926A patent/CA2303926A1/en not_active Abandoned
- 1998-09-09 HU HU0100276A patent/HUP0100276A3/hu unknown
- 1998-09-09 IL IL13507498A patent/IL135074A0/xx unknown
- 1998-09-09 AU AU91933/98A patent/AU9193398A/en not_active Abandoned
- 1998-09-09 KR KR1020007002824A patent/KR20010024078A/ko not_active Application Discontinuation
- 1998-09-09 DE DE69820103T patent/DE69820103T2/de not_active Expired - Fee Related
- 1998-09-09 CN CN98811095A patent/CN1278809A/zh active Pending
- 1998-09-09 SK SK287-2000A patent/SK2872000A3/sk unknown
- 1998-09-09 PL PL98339661A patent/PL339661A1/xx not_active Application Discontinuation
- 1998-09-09 US US09/171,572 patent/US6387899B1/en not_active Expired - Fee Related
- 1998-09-09 BR BR9812239-8A patent/BR9812239A/pt not_active IP Right Cessation
- 1998-09-09 EP EP98944378A patent/EP1025096B1/en not_active Expired - Lifetime
- 1998-09-09 JP JP2000511762A patent/JP4002392B2/ja not_active Expired - Fee Related
- 1998-09-09 AT AT98944378T patent/ATE255099T1/de not_active IP Right Cessation
- 1998-09-17 AR ARP980104637A patent/AR016651A1/es not_active Application Discontinuation
-
2000
- 2000-03-09 HR HR20000133A patent/HRP20000133A2/hr not_active Application Discontinuation
- 2000-03-14 IS IS5403A patent/IS5403A/is unknown
- 2000-03-17 NO NO20001403A patent/NO20001403L/no not_active Application Discontinuation
- 2000-08-31 US US09/653,552 patent/US6384225B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20000133A2 (en) | 2001-12-31 |
| EE200000144A (et) | 2001-02-15 |
| HUP0100276A2 (hu) | 2002-05-29 |
| IL135074A0 (en) | 2001-05-20 |
| HUP0100276A3 (en) | 2002-08-28 |
| SE9703378D0 (sv) | 1997-09-18 |
| KR20010024078A (ko) | 2001-03-26 |
| EP1025096A1 (en) | 2000-08-09 |
| DE69820103D1 (de) | 2004-01-08 |
| ZA987806B (en) | 1999-03-18 |
| CA2303926A1 (en) | 1999-03-25 |
| IS5403A (is) | 2000-03-14 |
| AU9193398A (en) | 1999-04-05 |
| US6384225B1 (en) | 2002-05-07 |
| JP2001516755A (ja) | 2001-10-02 |
| NO20001403D0 (no) | 2000-03-17 |
| BR9812239A (pt) | 2000-07-18 |
| SK2872000A3 (en) | 2000-11-07 |
| US6387899B1 (en) | 2002-05-14 |
| TR200000737T2 (tr) | 2000-09-21 |
| ATE255099T1 (de) | 2003-12-15 |
| DE69820103T2 (de) | 2004-09-02 |
| CN1278809A (zh) | 2001-01-03 |
| EP1025096B1 (en) | 2003-11-26 |
| NO20001403L (no) | 2000-05-18 |
| JP4002392B2 (ja) | 2007-10-31 |
| PL339661A1 (en) | 2001-01-02 |
| WO1999014213A1 (en) | 1999-03-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR016651A1 (es) | Derivados de 3,4-dihidro-2h-1-benzopirano substituidos con piperidinilo o piperazinilo, proceso para su preparacion, compuestos para su exclusivo uso endicho proceso, formulaciones farmaceuticas que comprenden dichos derivados y su uso para la elaboracion de un medicamento | |
| AR046193A2 (es) | Derivados de piperidil o piperazinil 1,2,3,4-tetrahidronaftaleno sustituido, formulacion farmaceutica, usos en la manufactura de medicamentos, y proceso para su preparacion | |
| AR015449A1 (es) | Derivados piperidil- o peperazinil-dihidro sustituidos-2h-1-benzopirano composicion farmaceutica que los contiene, su uso para la elaboracion de unmedicamento, procedimiento para su preparacion y compuesto intermediario para su exclusivo uso en dicho procedimiento | |
| AR034282A1 (es) | Derivados de difenilazetidinona, medicamentos que contienen estos compuestos, procedimiento para su preparacion, y su utilizacion para la preparacion de medicamentos | |
| BR0016611A (pt) | Moduladores de neurotransmissão de dopamina | |
| AR006360A1 (es) | Derivados de 1,2,3,4-tetrahidronaftaleno substituidos, uso de los mismos para la preparacion de medicamentos y procedimiento para su preparacion. | |
| AR008285A1 (es) | Antagonistas muscarinicos | |
| AR024819A1 (es) | Derivados de la n-(indolcarbonil)-piperazina, un procedimiento para su preparacion, su empleo para preparar un medicamento, los medicamentos a base de los mismos y las preparaciones farmaceuticas que los contienen. | |
| AR017182A1 (es) | Compuestos de aminotiazol, inhibidores de las kinasas dependientes de ciclinas y las composiciones farmaceuticas que los contienen. | |
| FR2678833B1 (fr) | Nouvelles compositions pharmaceutiques a base de derives de la classe des taxanes. | |
| AR033306A1 (es) | Compuestos | |
| AR068695A2 (es) | Uso de un compuesto de tiazol que comprende un derivado de tiazol para la fabricacion de un medicamento para la prevencion y el tratamiento de en-fermedades causadas por la produccion anormal de citocinas y/o la acele-racion de la adhesion de neutrofilos y/o la produccion anormal de tnf- alfa | |
| HUP0301777A2 (hu) | Tiroidreceptor-ligandum anilin-származékok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk | |
| TR199900314T2 (xx) | Eter muskarinik antagonistleri. | |
| AR035612A1 (es) | 4-(piperidin-4-ilmetil)benzamidas, o sus sales, esteres o solvatos, composiciones farmaceuticas que los comprenden, usos de los mismos para preparar medicamentos, y un kit para utilizar en el tratamiento de una enfermedad cognitiva o neurodegenerativa | |
| UY27716A1 (es) | Derivados de nitrosodifenilamina y composiciones farmacéuticas que los comprenden como medicamentos que se pueden utilizar en el tratamiento de patologías que se caracterizan por estrés oxidativo. | |
| AR002016A1 (es) | Derivados de 3-fenilisoquinoleina-1-(2h)-ona, procedimiento para su preparacion y medicamento y composicion farmaceutica que los contienen. | |
| AR030239A1 (es) | Fta lidas substituidas, un procedimiento para su preparacion y composiciones farmaceuticas que contienen las mismas | |
| AR019256A1 (es) | Utilizacion de derivados tetraciclo[6-6-2-0(2.27).0(9.14)] hexadeca-2(7), 3, 5, 9(14), 10,12-hexaeno, para la preparacion de preparados farmaceuticos conaccion inhibitoria de la fosfolipasa, los referidos derivados y preparado farmaceutico que contiene por lo menos a uno de dichos derivados | |
| AR030016A1 (es) | Derivados de 4-oxo-3,5-dihidro-4h-piridazino [4,5-b]indol-1-carboxamida, medicamento y composicion farmaceutica que comprenden a dichos derivados | |
| AR024818A1 (es) | Derivados de la n-(indolcarbonil)-piperazina, un procedimiento para su preparacion, su empleo para preparar un medicamento, los medicamentos a base de losmismos y las preparaciones farmaceuticas que los contienen. | |
| MX9405111A (es) | Nuevos derivados de (1-fenil-1-heterociclil)metanol y(1-fenil-1-heterociclil-metilamina). | |
| MX9202151A (es) | Derivados de carboestirilo y composiciones farmaceuticas que contienen los mismos para usarse como un agente mejorador del trastorno de la conciencia, estimulante del sistema nervioso central o agonista de receptor sigma | |
| AR033651A1 (es) | Derivados de pirimidina-2,4,6-triona, composiciones farmaceuticas que contienen dichos compuestos y el empleo de los mismos para la manufactura de un medicamento | |
| ES2159526T3 (es) | Nuevos derivados de 4-(3-benzofuranil)piperidinilo y 4-(3-benzotienil)piperidinilo y composiciones farmaceuticas que los contienen. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |