SE9703378D0 - New compounds - Google Patents

New compounds

Info

Publication number
SE9703378D0
SE9703378D0 SE9703378A SE9703378A SE9703378D0 SE 9703378 D0 SE9703378 D0 SE 9703378D0 SE 9703378 A SE9703378 A SE 9703378A SE 9703378 A SE9703378 A SE 9703378A SE 9703378 D0 SE9703378 D0 SE 9703378D0
Authority
SE
Sweden
Prior art keywords
alkyl
cycloalkyl
substituted
enantiomers
aryl
Prior art date
Application number
SE9703378A
Other languages
English (en)
Swedish (sv)
Inventor
Stefan Berg
Mats Linderberg
Svante Ross
Seth-Olov Thorberg
Bengt Ulff
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9703378A priority Critical patent/SE9703378D0/xx
Publication of SE9703378D0 publication Critical patent/SE9703378D0/xx
Priority to ZA987806A priority patent/ZA987806B/xx
Priority to CN98811095A priority patent/CN1278809A/zh
Priority to EEP200000144A priority patent/EE200000144A/xx
Priority to CA002303926A priority patent/CA2303926A1/en
Priority to SK287-2000A priority patent/SK2872000A3/sk
Priority to AT98944378T priority patent/ATE255099T1/de
Priority to HU0100276A priority patent/HUP0100276A3/hu
Priority to PCT/SE1998/001604 priority patent/WO1999014213A1/en
Priority to EP98944378A priority patent/EP1025096B1/en
Priority to AU91933/98A priority patent/AU9193398A/en
Priority to BR9812239-8A priority patent/BR9812239A/pt
Priority to DE69820103T priority patent/DE69820103T2/de
Priority to KR1020007002824A priority patent/KR20010024078A/ko
Priority to PL98339661A priority patent/PL339661A1/xx
Priority to US09/171,572 priority patent/US6387899B1/en
Priority to IL13507498A priority patent/IL135074A0/xx
Priority to JP2000511762A priority patent/JP4002392B2/ja
Priority to TR2000/00737T priority patent/TR200000737T2/xx
Priority to ARP980104637A priority patent/AR016651A1/es
Priority to HR20000133A priority patent/HRP20000133A2/hr
Priority to IS5403A priority patent/IS5403A/is
Priority to NO20001403A priority patent/NO20001403L/no
Priority to US09/653,552 priority patent/US6384225B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SE9703378A 1997-09-18 1997-09-18 New compounds SE9703378D0 (sv)

Priority Applications (24)

Application Number Priority Date Filing Date Title
SE9703378A SE9703378D0 (sv) 1997-09-18 1997-09-18 New compounds
ZA987806A ZA987806B (en) 1997-09-18 1998-08-27 Substituted chroman derivatives
TR2000/00737T TR200000737T2 (tr) 1997-09-18 1998-09-09 İkame edilmiş kroman türevleri.
AU91933/98A AU9193398A (en) 1997-09-18 1998-09-09 Substituted chroman derivatives
KR1020007002824A KR20010024078A (ko) 1997-09-18 1998-09-09 치환된 크로만 유도체
CA002303926A CA2303926A1 (en) 1997-09-18 1998-09-09 Substituted chroman derivatives
SK287-2000A SK2872000A3 (en) 1997-09-18 1998-09-09 Substituted chroman derivatives
AT98944378T ATE255099T1 (de) 1997-09-18 1998-09-09 Substituierte chromanderivate
HU0100276A HUP0100276A3 (en) 1997-09-18 1998-09-09 Substituted chroman derivatives, process for their preparation and medicaments containing them
PCT/SE1998/001604 WO1999014213A1 (en) 1997-09-18 1998-09-09 Substituted chroman derivatives
EP98944378A EP1025096B1 (en) 1997-09-18 1998-09-09 Substituted chroman derivatives
CN98811095A CN1278809A (zh) 1997-09-18 1998-09-09 取代的苯并二氢吡喃衍生物
BR9812239-8A BR9812239A (pt) 1997-09-18 1998-09-09 Composto, formulação farmacêutica, uso do composto, processos para o tratamento de distúrbios, para o tratamento de distúrbios mediados por 5-hidroxitriptamina, e, para a preparação do composto
DE69820103T DE69820103T2 (de) 1997-09-18 1998-09-09 Substituierte chromanderivate
EEP200000144A EE200000144A (et) 1997-09-18 1998-09-09 Asendatud kromaani derivaadid
PL98339661A PL339661A1 (en) 1997-09-18 1998-09-09 Substituted derivatives of chromane
US09/171,572 US6387899B1 (en) 1997-09-18 1998-09-09 Substituted chroman derivatives
IL13507498A IL135074A0 (en) 1997-09-18 1998-09-09 Substituted chroman derivatives
JP2000511762A JP4002392B2 (ja) 1997-09-18 1998-09-09 置換されたクロマン誘導体
ARP980104637A AR016651A1 (es) 1997-09-18 1998-09-17 Derivados de 3,4-dihidro-2h-1-benzopirano substituidos con piperidinilo o piperazinilo, proceso para su preparacion, compuestos para su exclusivo uso endicho proceso, formulaciones farmaceuticas que comprenden dichos derivados y su uso para la elaboracion de un medicamento
HR20000133A HRP20000133A2 (en) 1997-09-18 2000-03-09 Substituted chroman derivatives
IS5403A IS5403A (is) 1997-09-18 2000-03-14 Útskiptar króman afleiður
NO20001403A NO20001403L (no) 1997-09-18 2000-03-17 Substituerte kromanderivater
US09/653,552 US6384225B1 (en) 1997-09-18 2000-08-31 Intermediates in the preparation of substituted chroman derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9703378A SE9703378D0 (sv) 1997-09-18 1997-09-18 New compounds

Publications (1)

Publication Number Publication Date
SE9703378D0 true SE9703378D0 (sv) 1997-09-18

Family

ID=20408298

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9703378A SE9703378D0 (sv) 1997-09-18 1997-09-18 New compounds

Country Status (23)

Country Link
US (2) US6387899B1 (xx)
EP (1) EP1025096B1 (xx)
JP (1) JP4002392B2 (xx)
KR (1) KR20010024078A (xx)
CN (1) CN1278809A (xx)
AR (1) AR016651A1 (xx)
AT (1) ATE255099T1 (xx)
AU (1) AU9193398A (xx)
BR (1) BR9812239A (xx)
CA (1) CA2303926A1 (xx)
DE (1) DE69820103T2 (xx)
EE (1) EE200000144A (xx)
HR (1) HRP20000133A2 (xx)
HU (1) HUP0100276A3 (xx)
IL (1) IL135074A0 (xx)
IS (1) IS5403A (xx)
NO (1) NO20001403L (xx)
PL (1) PL339661A1 (xx)
SE (1) SE9703378D0 (xx)
SK (1) SK2872000A3 (xx)
TR (1) TR200000737T2 (xx)
WO (1) WO1999014213A1 (xx)
ZA (1) ZA987806B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9703377D0 (sv) * 1997-09-18 1997-09-18 Astra Ab New compounds
IL156595A0 (en) 2001-01-16 2004-01-04 Astrazeneca Ab Therapeutic heterocyclic compounds
BR0206513A (pt) 2001-01-16 2004-01-06 Astrazeneca Ab Composição, métodos de tratamento de um ser humano ou animal que sofre de depressão, ansiedade generalizada, distúrbios da alimentação, demência, distúrbio do p nico, distúrbios do sono, distúrbios gastrointestinais, distúrbios motores, distúrbios endócrinos, vasoespasmo e disfunção sexual, uso de qualquer um dos compostos, composição farmacêutica, e, processo para preparar compostos
BR0206514A (pt) * 2001-01-16 2004-01-06 Astrazeneca Ab Composto, método de tratamento de um ser humano ou animal que sofre de enxaqueca, uso do composto, composição farmacêutica, e, processo para preparar um composto
WO2002066454A1 (en) * 2001-02-21 2002-08-29 Sankyo Company, Limited Chromene derivatives
JP5080716B2 (ja) * 2001-07-20 2012-11-21 サイコジェニックス・インコーポレーテッド 注意欠陥・多動性障害の治療
GB0124020D0 (en) * 2001-10-05 2001-11-28 Astrazeneca Ab Chemical compounds
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
US20050065099A1 (en) * 2003-09-19 2005-03-24 Gail Walkinshaw Treatment of mitochondrial diseases
US20050165025A1 (en) * 2004-01-22 2005-07-28 Recordati Ireland Ltd. Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists
TWI346109B (en) * 2004-04-30 2011-08-01 Otsuka Pharma Co Ltd 4-amino-5-cyanopyrimidine derivatives
KR100681453B1 (ko) * 2005-03-22 2007-02-12 태남자동화기기 주식회사 권종 분류 기능을 구비한 지폐 방출기
US9066903B2 (en) 2006-02-28 2015-06-30 The United States Of America As Represented By The Department Of Veterans Affairs Pharmacological treatment of Parkinson's disease
WO2008130321A2 (en) * 2007-04-23 2008-10-30 Astrazeneca Ab Novel n-tetrahydronaphtalene or 5-heterocyclyl-chromane or 8-heterocyclyl-tetrahydronaphtalene derivatives for the treatment of pain
SA08290245B1 (ar) * 2007-04-23 2012-02-12 استرازينيكا ايه بي مشتقات كربو كساميد جديدة من -n (8-اريل رباعي هيدرو نفثالين غير متجانس- 2- يل) أو -n (5-اريل كرومان غير متجانس -3-يل) لعلاج الألم
WO2008130322A1 (en) * 2007-04-23 2008-10-30 Astrazeneca Ab Novel 5-heterocyclyl-chromane derivatives for the treatment of pain
WO2008130323A1 (en) * 2007-04-23 2008-10-30 Astrazeneca Ab Novel 8-piperazine-tetrahydronaphtalene derivatives for the treatment of pain
WO2008130319A2 (en) * 2007-04-23 2008-10-30 Astrazeneca Ab Novel n-tetrahydronaphtalene or n-chromane carboxamide derivatives for the treatment of pain

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04504721A (ja) 1989-04-27 1992-08-20 ジ・アップジョン・カンパニー 置換３―アミノ・クロマン類
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
SE8904361D0 (sv) * 1989-12-22 1989-12-22 Astra Ab New chroman and thiochroman derivatives
US5972935A (en) 1995-08-11 1999-10-26 Smithkline Beecham P.L.C. Biphenyl(thio)amide and bipennylethan(thi) one derivatives, their preparation and their use as 5-HT1D receptor antagonists

Also Published As

Publication number Publication date
HRP20000133A2 (en) 2001-12-31
EE200000144A (et) 2001-02-15
HUP0100276A2 (hu) 2002-05-29
IL135074A0 (en) 2001-05-20
HUP0100276A3 (en) 2002-08-28
AR016651A1 (es) 2001-07-25
KR20010024078A (ko) 2001-03-26
EP1025096A1 (en) 2000-08-09
DE69820103D1 (de) 2004-01-08
ZA987806B (en) 1999-03-18
CA2303926A1 (en) 1999-03-25
IS5403A (is) 2000-03-14
AU9193398A (en) 1999-04-05
US6384225B1 (en) 2002-05-07
JP2001516755A (ja) 2001-10-02
NO20001403D0 (no) 2000-03-17
BR9812239A (pt) 2000-07-18
SK2872000A3 (en) 2000-11-07
US6387899B1 (en) 2002-05-14
TR200000737T2 (tr) 2000-09-21
ATE255099T1 (de) 2003-12-15
DE69820103T2 (de) 2004-09-02
CN1278809A (zh) 2001-01-03
EP1025096B1 (en) 2003-11-26
NO20001403L (no) 2000-05-18
JP4002392B2 (ja) 2007-10-31
PL339661A1 (en) 2001-01-02
WO1999014213A1 (en) 1999-03-25

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