AR016382A1 - Uso de un derivado del acido bencil-indazol metoxialcanoico. - Google Patents
Uso de un derivado del acido bencil-indazol metoxialcanoico.Info
- Publication number
- AR016382A1 AR016382A1 ARP980103695A ARP980103695A AR016382A1 AR 016382 A1 AR016382 A1 AR 016382A1 AR P980103695 A ARP980103695 A AR P980103695A AR P980103695 A ARP980103695 A AR P980103695A AR 016382 A1 AR016382 A1 AR 016382A1
- Authority
- AR
- Argentina
- Prior art keywords
- acid derivative
- metoxialcanoic
- bencil
- indazol
- alkyl
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- XSFVAQRSZSENGO-UHFFFAOYSA-N 3-benzyl-2h-indazole Chemical compound N1N=C2C=CC=CC2=C1CC1=CC=CC=C1 XSFVAQRSZSENGO-UHFFFAOYSA-N 0.000 abstract 1
- 102100021943 C-C motif chemokine 2 Human genes 0.000 abstract 1
- 101710155857 C-C motif chemokine 2 Proteins 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Surgery (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97MI001789A IT1293795B1 (it) | 1997-07-28 | 1997-07-28 | Farmaco attivo nel ridurre la produzione di proteina mcp-1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR016382A1 true AR016382A1 (es) | 2001-07-04 |
Family
ID=11377642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980103695A AR016382A1 (es) | 1997-07-28 | 1998-07-28 | Uso de un derivado del acido bencil-indazol metoxialcanoico. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6534534B1 (enExample) |
| EP (1) | EP1005332B1 (enExample) |
| JP (2) | JP4651191B2 (enExample) |
| AR (1) | AR016382A1 (enExample) |
| AT (1) | ATE251902T1 (enExample) |
| AU (1) | AU744492B2 (enExample) |
| CA (1) | CA2300289C (enExample) |
| DE (1) | DE69819012T2 (enExample) |
| DK (1) | DK1005332T3 (enExample) |
| ES (1) | ES2207858T3 (enExample) |
| IT (1) | IT1293795B1 (enExample) |
| PT (1) | PT1005332E (enExample) |
| SI (1) | SI1005332T1 (enExample) |
| WO (1) | WO1999004770A2 (enExample) |
| ZA (1) | ZA986636B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1293795B1 (it) * | 1997-07-28 | 1999-03-10 | Angelini Ricerche Spa | Farmaco attivo nel ridurre la produzione di proteina mcp-1 |
| US7238711B1 (en) | 1999-03-17 | 2007-07-03 | Cambridge University Technical Services Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
| ITMI20062254A1 (it) * | 2006-11-24 | 2008-05-25 | Acraf | Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca |
| LT2254869T (lt) | 2008-03-07 | 2017-08-10 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | Nauji 1-benzil-3-hidroksimetilindazolo dariniai ir jų panaudojimas gydyme ligų, susijusių su cx3cr1 ir p40 raiška |
| CA2714436C (en) | 2008-03-07 | 2017-06-27 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | Novel 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of mcp-1, cx3cr1 and p40 |
| JP5509102B2 (ja) | 2008-03-07 | 2014-06-04 | アジェンデ・キミケ・リウニテ・アンジェリニ・フランチェスコ・ア・チ・エレ・ア・エフェ・ソシエタ・ペル・アチオニ | 新規な１−ベンジル−３−ヒドロキシメチルインダゾール誘導体およびそのｍｃｐ−１およびｃｘ３ｃｒ１の発現に基づく疾患の治療への使用 |
| PL2462119T3 (pl) | 2009-08-03 | 2014-10-31 | Acraf | Sposób wytwarzania 1-benzylo-3-hydroksymetylo-1H-indazolu i jego pochodnych oraz potrzebnych magnezowych związków pośrednich |
| UA108742C2 (uk) * | 2009-09-23 | 2015-06-10 | Фармацевтична композиція для лікування запальних захворювань, опосередкованих mcp-1 | |
| US9250253B2 (en) | 2010-02-25 | 2016-02-02 | Prairie Ventures, L.L.C. | System and method for anatomical pathology sample handling, storage, and analysis |
| US8999292B2 (en) | 2012-05-01 | 2015-04-07 | Translatum Medicus Inc. | Methods for treating and diagnosing blinding eye diseases |
| EP3142664B1 (en) * | 2014-05-15 | 2019-12-04 | Translatum Medicus Inc. | Compositions and methods for treating and diagnosing ocular disorders |
| WO2016201426A1 (en) | 2015-06-12 | 2016-12-15 | Vettore, LLC | Mct4 inhibitors for treating disease |
| IL279949B2 (en) | 2016-12-12 | 2025-03-01 | Vettore Llc | Heterocyclic MCT4 inhibitors |
| US11753382B2 (en) | 2019-06-25 | 2023-09-12 | Translatum Medicus Inc. | Processes of making 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1230441B (it) | 1989-02-07 | 1991-10-23 | Acraf | Eteri della serie dell'indazolo |
| US5100899A (en) * | 1989-06-06 | 1992-03-31 | Roy Calne | Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof |
| IT1253703B (it) * | 1991-04-22 | 1995-08-23 | Angelini Francesco Ist Ricerca | Uso di acidi metossi alcanoici dell'indazolo per preparare un farmaco attivo nel trattamento di malattie autoimmunitarie |
| WO1994009128A1 (en) * | 1992-10-22 | 1994-04-28 | Mallinckrodt Medical, Inc. | Therapeutic treatment for inhibiting vascular restenosis |
| US5563145A (en) * | 1994-12-07 | 1996-10-08 | American Home Products Corporation | Rapamycin 42-oximes and hydroxylamines |
| JPH08333262A (ja) * | 1995-04-07 | 1996-12-17 | Chugai Pharmaceut Co Ltd | 免疫抑制剤 |
| US6113898A (en) * | 1995-06-07 | 2000-09-05 | Idec Pharmaceuticals Corporation | Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies |
| DE19538402A1 (de) * | 1995-10-14 | 1997-04-17 | Boehringer Mannheim Gmbh | Lipidalkohole als neue immunsuppressive und antivirale Arzneimittel |
| JPH09165339A (ja) * | 1995-10-27 | 1997-06-24 | American Home Prod Corp | ラパマイシンを付与したドナー脾細胞を用いる臓器移植の延長 |
| IT1276031B1 (it) * | 1995-10-31 | 1997-10-24 | Angelini Ricerche Spa | Composizione farmaceutica per il trattamento delle malattie autoimmuni |
| US5780462A (en) * | 1995-12-27 | 1998-07-14 | American Home Products Corporation | Water soluble rapamycin esters |
| IT1293795B1 (it) * | 1997-07-28 | 1999-03-10 | Angelini Ricerche Spa | Farmaco attivo nel ridurre la produzione di proteina mcp-1 |
-
1997
- 1997-07-28 IT IT97MI001789A patent/IT1293795B1/it active IP Right Grant
-
1998
- 1998-07-22 WO PCT/EP1998/004924 patent/WO1999004770A2/en not_active Ceased
- 1998-07-22 ES ES98943862T patent/ES2207858T3/es not_active Expired - Lifetime
- 1998-07-22 DK DK98943862T patent/DK1005332T3/da active
- 1998-07-22 EP EP98943862A patent/EP1005332B1/en not_active Expired - Lifetime
- 1998-07-22 US US09/463,666 patent/US6534534B1/en not_active Expired - Lifetime
- 1998-07-22 DE DE69819012T patent/DE69819012T2/de not_active Expired - Lifetime
- 1998-07-22 AU AU91601/98A patent/AU744492B2/en not_active Ceased
- 1998-07-22 SI SI9830573T patent/SI1005332T1/xx unknown
- 1998-07-22 CA CA002300289A patent/CA2300289C/en not_active Expired - Fee Related
- 1998-07-22 AT AT98943862T patent/ATE251902T1/de active
- 1998-07-22 JP JP2000503829A patent/JP4651191B2/ja not_active Expired - Fee Related
- 1998-07-22 PT PT98943862T patent/PT1005332E/pt unknown
- 1998-07-24 ZA ZA986636A patent/ZA986636B/xx unknown
- 1998-07-28 AR ARP980103695A patent/AR016382A1/es unknown
-
2009
- 2009-11-09 JP JP2009270715A patent/JP5086322B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IT1293795B1 (it) | 1999-03-10 |
| CA2300289A1 (en) | 1999-02-04 |
| JP2010047609A (ja) | 2010-03-04 |
| HK1028561A1 (en) | 2001-02-23 |
| SI1005332T1 (en) | 2004-02-29 |
| US6534534B1 (en) | 2003-03-18 |
| DE69819012D1 (de) | 2003-11-20 |
| JP5086322B2 (ja) | 2012-11-28 |
| DK1005332T3 (da) | 2004-02-09 |
| WO1999004770A3 (en) | 1999-04-15 |
| ZA986636B (en) | 1999-02-04 |
| AU744492B2 (en) | 2002-02-28 |
| JP4651191B2 (ja) | 2011-03-16 |
| AU9160198A (en) | 1999-02-16 |
| JP2001510793A (ja) | 2001-08-07 |
| CA2300289C (en) | 2007-11-20 |
| ES2207858T3 (es) | 2004-06-01 |
| WO1999004770A2 (en) | 1999-02-04 |
| ITMI971789A1 (it) | 1999-01-28 |
| PT1005332E (pt) | 2004-03-31 |
| EP1005332A2 (en) | 2000-06-07 |
| DE69819012T2 (de) | 2004-08-12 |
| ATE251902T1 (de) | 2003-11-15 |
| EP1005332B1 (en) | 2003-10-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR016382A1 (es) | Uso de un derivado del acido bencil-indazol metoxialcanoico. | |
| ECSP941104A (es) | Derivados de 2,6 diaminopurina, procedimiento para su preparacion y composiciones farmaceuticas que los contienen | |
| MX9302448A (es) | Derivados iminicos ciclicos, procedimientos para su preparacion y medicamentos que contienen estos compuestos. | |
| AR026410A1 (es) | ''2-aril-3-(heteroaril)-imidazo[1,2-a]pirimidinas sustituidas, y las composiciones y metodos farmaceuticos relacionados | |
| GT199800180A (es) | Derivados de la tienopirimidina y de la tienopiridina utiles como agentes anticancerigenos. | |
| AR029174A1 (es) | Derivados de espirooxindol, proceso para su preparacion, formulacion farmaceutica, y utilizacion de los derivados en la manufactura de medicamentos | |
| PA8487601A1 (es) | Derivados biciclicos sustituidos utiles como agentes contra el cancer | |
| AR037517A1 (es) | Derivados de naftiridinas, un proceso para su preparacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento para el tratamiento de una enfermedad inflamatoria | |
| MX9202747A (es) | Nuevas sulfonamidas y procedimientos para su preparacion. | |
| AR025959A1 (es) | DERIVADOS DE TER.-BUTIL-(7-METIL-IMIDAZO[1,2,a]PIRIDIN-3-IL)-AMINA, PROCEDIMIENTO PARA SU PREPARACION, MEDICAMENTOS QUE LOS CONTIENEN, SU USO PARA LAPREPARACION DE UN MEDICAMENTO PARA LA INHIBICION DE NO-SINTASA Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN | |
| ES2087916T3 (es) | Derivado de pirimidina biciclico, metodo para producir el mismo, y preparacion farmaceutica que contiene el mismo como ingrediente activo. | |
| MX9301348A (es) | Nuevos compuestos que tienen actividad farmacologica, proceso para su preparacion y composicion farmaceutica que los comprende. | |
| ES2160640T3 (es) | Nuevos (r)-5-carbamoil-8-fluoro-3-amino disustituido en n,n-3,4-dihidro-2h-1-benzopiranos. | |
| AR029825A1 (es) | Una composicion farmaceuticamente aceptable que comprende carvedilol o una sal del mismo farmaceuticamente aceptable, un procedimiento para la produccion de dicha composicion y utilizacion de la misma | |
| UY26372A1 (es) | "imidazo-3-il-aminas bicíclicas procedimiento para su preparación y medicamentos que las contienen " | |
| ES2069410T3 (es) | Nuevos derivados del acido hidroxamico y n-hidroxiurea y su uso. | |
| ES2143132T3 (es) | Monohidratos de derivado de acido aminobenceno-sulfonico y su metodo de preparacion. | |
| ES2084339T3 (es) | Tetrahidropiridinas e hidroxipiperidinas sustituidas utiles como agentes para el sistema nervioso central. | |
| ECSP045469A (es) | El uso de cianopirrolidinas sustituidas y preparaciones de combinacion que las contienen para tratar hiperlipidemia y enfermedades asociadas | |
| PT92821A (pt) | Processo para a preparacao composicoes farmaceuticas para o combate de doencas do tipo psoriase, bem como doencas inflamatorias, incorporando azelastina como substancia activa | |
| EA200200096A1 (ru) | Новые производные витамина d с циклическими субструктурами в боковых цепях, способ и промежуточные продукты для их получения и их применение для получения лекарственных средств | |
| ES2060173T3 (es) | Derivados de lisolecitina para el tratamiento de enfermedades autoinmunologicas. | |
| ES2123873T3 (es) | Pirrolocarbazol. | |
| ES2038074A1 (es) | Nuevos derivados de benzimidazol, su preparacion y su aplicacion como medicamentos. | |
| ES2111352T3 (es) | Uso de diester fosfato para el tratamiento de enfermedades retinianas. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |