AR015105A1 - Una composicion que comprende derivados de urea o carbonato y factores neurotroficos para estimular el crecimiento de neuritas en celulas nerviosas y unmedicamento que la comprende - Google Patents
Una composicion que comprende derivados de urea o carbonato y factores neurotroficos para estimular el crecimiento de neuritas en celulas nerviosas y unmedicamento que la comprendeInfo
- Publication number
- AR015105A1 AR015105A1 ARP970105320A ARP970105320A AR015105A1 AR 015105 A1 AR015105 A1 AR 015105A1 AR P970105320 A ARP970105320 A AR P970105320A AR P970105320 A ARP970105320 A AR P970105320A AR 015105 A1 AR015105 A1 AR 015105A1
- Authority
- AR
- Argentina
- Prior art keywords
- growth
- neurites
- stimulate
- understands
- medicine
- Prior art date
Links
- 108010025020 Nerve Growth Factor Proteins 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 5
- 102000007072 Nerve Growth Factors Human genes 0.000 title abstract 3
- 239000003900 neurotrophic factor Substances 0.000 title abstract 3
- 210000002241 neurite Anatomy 0.000 title abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
- 239000004202 carbamide Substances 0.000 title 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical class OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 title 1
- 210000004027 cell Anatomy 0.000 title 1
- 102000015336 Nerve Growth Factor Human genes 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229940053128 nerve growth factor Drugs 0.000 abstract 2
- 210000002569 neuron Anatomy 0.000 abstract 2
- 208000014674 injury Diseases 0.000 abstract 1
- 230000003961 neuronal insult Effects 0.000 abstract 1
- 230000000508 neurotrophic effect Effects 0.000 abstract 1
- 230000008733 trauma Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/749,114 US5780484A (en) | 1996-11-13 | 1996-11-13 | Methods for stimulating neurite growth with piperidine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR015105A1 true AR015105A1 (es) | 2001-04-18 |
Family
ID=25012320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970105320A AR015105A1 (es) | 1996-11-13 | 1997-11-13 | Una composicion que comprende derivados de urea o carbonato y factores neurotroficos para estimular el crecimiento de neuritas en celulas nerviosas y unmedicamento que la comprende |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5780484A (enEXAMPLES) |
| EP (2) | EP0941113A1 (enEXAMPLES) |
| JP (1) | JP2001503778A (enEXAMPLES) |
| KR (1) | KR100537866B1 (enEXAMPLES) |
| CN (1) | CN1168443C (enEXAMPLES) |
| AR (1) | AR015105A1 (enEXAMPLES) |
| AU (1) | AU741186B2 (enEXAMPLES) |
| BR (1) | BR9713037A (enEXAMPLES) |
| CA (1) | CA2270985A1 (enEXAMPLES) |
| CO (1) | CO5080733A1 (enEXAMPLES) |
| EA (1) | EA003530B1 (enEXAMPLES) |
| IL (1) | IL129557A0 (enEXAMPLES) |
| IN (1) | IN183409B (enEXAMPLES) |
| NZ (1) | NZ335396A (enEXAMPLES) |
| PL (1) | PL191249B1 (enEXAMPLES) |
| TW (1) | TW509572B (enEXAMPLES) |
| UA (1) | UA61090C2 (enEXAMPLES) |
| WO (1) | WO1998020893A1 (enEXAMPLES) |
| ZA (1) | ZA9710248B (enEXAMPLES) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6133456A (en) * | 1994-08-18 | 2000-10-17 | Ariad Gene Therapeutics, Inc. | Synthetic multimerizing agents |
| US20030036654A1 (en) * | 1994-08-18 | 2003-02-20 | Holt Dennis A. | Synthetic multimerizing agents |
| US6150527A (en) * | 1994-08-18 | 2000-11-21 | Ariad Pharmaceuticals, Inc. | Synthetic multimerizing agents |
| US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| US6242468B1 (en) * | 1997-02-27 | 2001-06-05 | Jia-He Li | Carbamate and urea compositions and neurotrophic uses |
| ZA98825B (en) * | 1997-02-27 | 1998-10-19 | Guilford Pharm Inc | Method of using neurotrophic carbamates and ureas |
| US6514686B2 (en) | 1997-04-28 | 2003-02-04 | The University Of British Columbia | Method and composition for modulating amyloidosis |
| US20010049381A1 (en) | 1997-06-04 | 2001-12-06 | Gpl Nil Holdings, Inc., | Pyrrolidine derivative hair growth compositions and uses |
| US5945441A (en) | 1997-06-04 | 1999-08-31 | Gpi Nil Holdings, Inc. | Pyrrolidine carboxylate hair revitalizing agents |
| US6852496B1 (en) | 1997-08-12 | 2005-02-08 | Oregon Health And Science University | Methods of screening for agents that promote nerve cell growth |
| US5968921A (en) * | 1997-10-24 | 1999-10-19 | Orgegon Health Sciences University | Compositions and methods for promoting nerve regeneration |
| CN1299346A (zh) * | 1998-06-03 | 2001-06-13 | Gpi;Nil控股公司 | N-杂环羧酸或羧酸等排物的脲和氨基羧酸酯 |
| US6331537B1 (en) | 1998-06-03 | 2001-12-18 | Gpi Nil Holdings, Inc. | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds |
| CA2334002A1 (en) | 1998-06-03 | 1999-12-09 | Mark H. Norman | N-linked sulphonamides of n-heterocyclic carboxylic acids or carboxylic acid isosteres |
| EA200100149A1 (ru) | 1998-07-17 | 2001-08-27 | Агурон Фармасьютикалз, Инк. | Соединения, композиции и способы стимуляции роста и удлинения нейронов |
| GB9815880D0 (en) | 1998-07-21 | 1998-09-16 | Pfizer Ltd | Heterocycles |
| US7338976B1 (en) * | 1998-08-14 | 2008-03-04 | Gpi Nil Holdings, Inc. | Heterocyclic esters or amides for vision and memory disorders |
| US6376517B1 (en) * | 1998-08-14 | 2002-04-23 | Gpi Nil Holdings, Inc. | Pipecolic acid derivatives for vision and memory disorders |
| US6395758B1 (en) * | 1998-08-14 | 2002-05-28 | Gpi Nil Holdings, Inc. | Small molecule carbamates or ureas for vision and memory disorders |
| US6462072B1 (en) | 1998-09-21 | 2002-10-08 | Gpi Nil Holdings, Inc. | Cyclic ester or amide derivatives |
| US6228872B1 (en) * | 1998-11-12 | 2001-05-08 | Bristol-Myers Squibb Company | Neurotrophic diamide and carbamate agents |
| AU6073300A (en) | 1999-07-06 | 2001-01-22 | Vertex Pharmaceuticals Incorporated | N-heterocyclic derivatives with neuronal activity |
| US6734211B1 (en) | 1999-07-09 | 2004-05-11 | Oregon Health & Sciences University | Compositions and methods for promoting nerve regeneration |
| BR0012327A (pt) * | 1999-07-09 | 2002-07-02 | Ortho Mcneil Pharm Inc | Pirrolidinas e piperidinas neurotróficas, e composições e métodos relacionados |
| EP1214293A1 (en) | 1999-09-08 | 2002-06-19 | Guilford Pharmaceuticals Inc. | Non-peptidic cyclophilin binding compounds and their use |
| ATE335524T1 (de) * | 1999-11-12 | 2006-09-15 | Alcon Inc | Verwendung von neurophilin liganden zur behandlung von augenerkrankungen |
| US7253169B2 (en) | 1999-11-12 | 2007-08-07 | Gliamed, Inc. | Aza compounds, pharmaceutical compositions and methods of use |
| US6417189B1 (en) | 1999-11-12 | 2002-07-09 | Gpi Nil Holdings, Inc. | AZA compounds, pharmaceutical compositions and methods of use |
| US6818643B1 (en) | 1999-12-08 | 2004-11-16 | Bristol-Myers Squibb Company | Neurotrophic bicyclic diamides |
| WO2001046195A1 (en) | 1999-12-21 | 2001-06-28 | Gpi Nil Holdings, Inc. | Hydantoin derivative compounds, pharmaceutical compositions, and methods of using same |
| JP2004532187A (ja) | 2001-01-25 | 2004-10-21 | ギルフォード ファーマシュウティカルズ インコーポレイテッド | 三置換カルボサイクリックサイクロフィリン結合化合物とその用途 |
| JP2005500270A (ja) * | 2001-05-29 | 2005-01-06 | ギルフォード ファーマシュウティカルズ インコーポレイテッド | 手術の結果として発生した神経損傷を治療するための方法 |
| US20040147433A1 (en) * | 2001-06-14 | 2004-07-29 | Marcus Keep | Neuroimmunophilins for selective neuronal radioprotection |
| US6635892B2 (en) * | 2002-01-24 | 2003-10-21 | Pei Electronics, Inc. | Compact integrated infrared scene projector |
| WO2004031148A1 (en) * | 2002-10-03 | 2004-04-15 | Vertex Pharmaceuticals Incorporated | Piperazine and piperidine derivatives for treatment of neurological diseases |
| US20060189551A1 (en) * | 2004-10-04 | 2006-08-24 | Duke University | Combination therapies for fungal pathogens |
| CA2590254A1 (en) | 2004-12-20 | 2006-06-29 | Wyeth | Rapamycin derivatives and the uses thereof in the treatment of neurological disorders |
| WO2006068932A2 (en) * | 2004-12-20 | 2006-06-29 | Wyeth | Rapamycin analogues and the uses thereof in the treatment of neurological, proliferative, and inflammatory disorders |
| DK1849773T3 (da) * | 2005-02-17 | 2013-11-04 | Astellas Pharma Inc | Piperazinderivater til behandlingen af urininkontinens og smerte |
| DOP2007000021A (es) * | 2006-02-02 | 2007-08-31 | Rinat Neuroscience Corp | Procedimientos para tratar pérdida de peso no deseada o trastornos alimentarios administrando un agonista de trkb |
| WO2007088479A1 (en) * | 2006-02-02 | 2007-08-09 | Rinat Neuroscience Corp. | Methods for treating obesity by administering a trkb antagonist |
| JP2021525737A (ja) | 2018-05-30 | 2021-09-27 | ザップ サージカル システムズ, インコーポレイテッド | 重要構造近くにおける放射線外科的神経調節 |
| CN116763768A (zh) * | 2022-03-15 | 2023-09-19 | 润佳(苏州)医药科技有限公司 | 同位素富集的3-氨基-1-丙磺酸衍生物及其用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192773A (en) * | 1990-07-02 | 1993-03-09 | Vertex Pharmaceuticals, Inc. | Immunosuppressive compounds |
| JP3145709B2 (ja) * | 1991-05-09 | 2001-03-12 | バーテックス ファーマシューティカルズ インコーポレイテッド | 新規な免疫抑制化合物 |
| NZ314207A (en) * | 1992-09-28 | 2000-12-22 | Vertex Pharma | 1-(2-Oxoacetyl)-piperidine-2-carboxylic acid derivatives as multi drug resistant cancer cell sensitizers |
| US5744485A (en) * | 1994-03-25 | 1998-04-28 | Vertex Pharmaceuticals Incorporated | Carbamates and ureas as modifiers of multi-drug resistance |
| IL115685A (en) * | 1994-11-16 | 2000-08-31 | Vertex Pharma | Amino acid derivatives pharmaceutical compositions containing the same and processes for the preparation thereof |
| US5543423A (en) * | 1994-11-16 | 1996-08-06 | Vertex Pharmaceuticals, Incorporated | Amino acid derivatives with improved multi-drug resistance activity |
| US5726184A (en) * | 1995-05-19 | 1998-03-10 | Vertex Pharmaceuticals Incorporated | Tetralin compounds with improved MDR activity |
| US5614547A (en) * | 1995-06-07 | 1997-03-25 | Guilford Pharmaceuticals Inc. | Small molecule inhibitors of rotamase enzyme |
| US5696135A (en) * | 1995-06-07 | 1997-12-09 | Gpi Nil Holdings, Inc. | Inhibitors of rotamase enzyme activity effective at stimulating neuronal growth |
| US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| US6037370A (en) * | 1995-06-08 | 2000-03-14 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
| US5801197A (en) * | 1995-10-31 | 1998-09-01 | Gpi Nil Holdings, Inc. | Rotamase enzyme activity inhibitors |
| US5811434A (en) * | 1996-11-13 | 1998-09-22 | Vertex Pharmacueticals Incorporated | Methods and compositions for stimulating neurite growth |
| US5840736A (en) * | 1996-11-13 | 1998-11-24 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
| CN104718162B (zh) * | 2012-09-28 | 2017-11-21 | Dic株式会社 | α‑氧化铝微粒以及其制造方法 |
-
1996
- 1996-11-13 US US08/749,114 patent/US5780484A/en not_active Expired - Lifetime
-
1997
- 1997-11-13 JP JP52286798A patent/JP2001503778A/ja active Pending
- 1997-11-13 AR ARP970105320A patent/AR015105A1/es not_active Application Discontinuation
- 1997-11-13 BR BR9713037-0A patent/BR9713037A/pt not_active Application Discontinuation
- 1997-11-13 EA EA199900463A patent/EA003530B1/ru not_active IP Right Cessation
- 1997-11-13 CA CA002270985A patent/CA2270985A1/en not_active Abandoned
- 1997-11-13 TW TW086116912A patent/TW509572B/zh not_active IP Right Cessation
- 1997-11-13 EP EP97948309A patent/EP0941113A1/en not_active Ceased
- 1997-11-13 UA UA99063269A patent/UA61090C2/uk unknown
- 1997-11-13 CO CO97066753A patent/CO5080733A1/es unknown
- 1997-11-13 AU AU54397/98A patent/AU741186B2/en not_active Ceased
- 1997-11-13 CN CNB971802483A patent/CN1168443C/zh not_active Expired - Fee Related
- 1997-11-13 EP EP06000328A patent/EP1666053A1/en not_active Ceased
- 1997-11-13 ZA ZA9710248A patent/ZA9710248B/xx unknown
- 1997-11-13 NZ NZ335396A patent/NZ335396A/xx unknown
- 1997-11-13 IL IL12955797A patent/IL129557A0/xx not_active IP Right Cessation
- 1997-11-13 PL PL333286A patent/PL191249B1/pl not_active IP Right Cessation
- 1997-11-13 KR KR10-1999-7004194A patent/KR100537866B1/ko not_active Expired - Fee Related
- 1997-11-13 IN IN2147CA1997 patent/IN183409B/en unknown
- 1997-11-13 WO PCT/US1997/020868 patent/WO1998020893A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100537866B1 (ko) | 2005-12-21 |
| EA199900463A1 (ru) | 2000-02-28 |
| PL191249B1 (pl) | 2006-04-28 |
| AU5439798A (en) | 1998-06-03 |
| US5780484A (en) | 1998-07-14 |
| IL129557A0 (en) | 2000-02-29 |
| BR9713037A (pt) | 2000-04-11 |
| NZ335396A (en) | 2000-11-24 |
| CO5080733A1 (es) | 2001-09-25 |
| CN1239434A (zh) | 1999-12-22 |
| WO1998020893A1 (en) | 1998-05-22 |
| JP2001503778A (ja) | 2001-03-21 |
| CN1168443C (zh) | 2004-09-29 |
| UA61090C2 (uk) | 2003-11-17 |
| IN183409B (enEXAMPLES) | 1999-12-25 |
| ZA9710248B (en) | 1998-05-28 |
| KR20000068964A (ko) | 2000-11-25 |
| EA003530B1 (ru) | 2003-06-26 |
| CA2270985A1 (en) | 1998-05-22 |
| TW509572B (en) | 2002-11-11 |
| PL333286A1 (en) | 1999-11-22 |
| AU741186B2 (en) | 2001-11-22 |
| EP1666053A1 (en) | 2006-06-07 |
| EP0941113A1 (en) | 1999-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |