AR009092A1 - Un procedimiento para preparar 2'-fluoro-5-metil-beta-l- arabinofuranosiluridina. - Google Patents

Un procedimiento para preparar 2'-fluoro-5-metil-beta-l- arabinofuranosiluridina.

Info

Publication number
AR009092A1
AR009092A1 ARP970104409A ARP970104409A AR009092A1 AR 009092 A1 AR009092 A1 AR 009092A1 AR P970104409 A ARP970104409 A AR P970104409A AR P970104409 A ARP970104409 A AR P970104409A AR 009092 A1 AR009092 A1 AR 009092A1
Authority
AR
Argentina
Prior art keywords
arabinofuranosiluridine
preparing
procedure
fluoro
beta
Prior art date
Application number
ARP970104409A
Other languages
English (en)
Spanish (es)
Original Assignee
Univ Georgia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Georgia filed Critical Univ Georgia
Publication of AR009092A1 publication Critical patent/AR009092A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02—Monosaccharides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ARP970104409A 1997-07-23 1997-09-25 Un procedimiento para preparar 2'-fluoro-5-metil-beta-l- arabinofuranosiluridina. AR009092A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5348897P 1997-07-23 1997-07-23

Publications (1)

Publication Number Publication Date
AR009092A1 true AR009092A1 (es) 2000-03-08

Family

ID=21984622

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970104409A AR009092A1 (es) 1997-07-23 1997-09-25 Un procedimiento para preparar 2'-fluoro-5-metil-beta-l- arabinofuranosiluridina.

Country Status (21)

Country Link
US (2) US6512107B2 (enExample)
EP (2) EP1327637B1 (enExample)
KR (1) KR100247505B1 (enExample)
CN (1) CN1113892C (enExample)
AR (1) AR009092A1 (enExample)
AT (2) ATE304547T1 (enExample)
AU (1) AU8758298A (enExample)
BR (1) BR9810804B1 (enExample)
DE (2) DE69831619T2 (enExample)
DK (1) DK1327637T3 (enExample)
ES (2) ES2249678T3 (enExample)
ID (1) ID20624A (enExample)
IL (1) IL121730A (enExample)
IN (1) IN186807B (enExample)
MY (1) MY117314A (enExample)
PT (2) PT1327637E (enExample)
SA (1) SA98180771B1 (enExample)
SI (1) SI1327637T1 (enExample)
TR (1) TR199701051A3 (enExample)
TW (1) TW434252B (enExample)
WO (2) WO1999005157A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW434252B (en) 1997-07-23 2001-05-16 Univ Georgia Res Found Process for the preparation of 2'-fluoro-5-methyl-β-L-arabino-furanosyluridine
KR100449618B1 (ko) * 1998-03-27 2004-11-16 부광약품 주식회사 2'-플루오로-5-메틸-β-L-아라비노푸라노실유리딘의 제조방법
US6462191B1 (en) * 2000-07-13 2002-10-08 Air Products And Chemicals, Inc. Synthesis of 2-deoxy-2-fluoro-arabinose derivatives
KR100910791B1 (ko) * 2001-03-30 2009-08-04 부광약품 주식회사 2'-할로-β-Ｌ-아라비노퓨라노실 뉴클레오사이드의 제조방법
KR100487992B1 (ko) * 2001-10-25 2005-05-09 부광약품 주식회사 2'-플루오로-5-메틸-β-엘-아라비노푸라노실유리딘의 황유도체
CA2470938A1 (en) * 2001-12-20 2003-07-03 Raymond F. Schinazi Treatment of ebv and khsv infection and associated abnormal cellular proliferation
KR100976778B1 (ko) 2003-04-17 2010-08-18 부광약품 주식회사 1-（2'-플루오로-베타-엘-아라비노푸라노실）티민의 황 유도체를 유효 활성 성분으로 하는 b형 간염 바이러스 치료제
AU2005285045B2 (en) 2004-09-14 2011-10-13 Gilead Sciences, Inc. Preparation of 2'fluoro-2'- alkyl- substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives
CN103735560A (zh) 2005-06-07 2014-04-23 耶鲁大学 使用克来夫定和替比夫定治疗癌症和其它病症或疾病状态的方法
CN102066369B (zh) 2007-06-18 2013-05-29 广东东阳光药业有限公司 一种溴苯基-取代的噻唑二氢嘧啶
GB0907551D0 (en) 2009-05-01 2009-06-10 Univ Dundee Treatment or prophylaxis of proliferative conditions
EA202091856A1 (ru) 2018-02-02 2020-12-07 Маверикс Онколоджи, Инк. Низкомолекулярные лекарственные коньюгаты гемцитабина монофосфата
CN109320564B (zh) * 2018-10-26 2022-05-31 浙江晟格生物科技有限公司 一种l-来苏糖的制备工艺
CN109467583A (zh) * 2018-11-17 2019-03-15 扬州工业职业技术学院 一种克拉夫定的绿色合成工艺
CN109467541A (zh) * 2018-11-17 2019-03-15 扬州工业职业技术学院 一种绿色合成克拉夫定药物中间体的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3714473A1 (de) * 1987-04-30 1988-11-10 Basf Ag Kontinuierliches verfahren zur epimerisierung von zuckern, insbesondere von d-arabinose zu d-ribose
EP0400064B1 (en) 1988-02-09 1993-04-21 Uop Solid catalysts for continuous interconversion of epimeric aldoses and aldose analogs
DE4002727A1 (de) * 1990-01-31 1991-08-01 Bayer Ag Mischungen aus waessrigen polymerdispersionen
US5587362A (en) 1994-01-28 1996-12-24 Univ. Of Ga Research Foundation L-nucleosides
US5808040A (en) 1995-01-30 1998-09-15 Yale University L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides
TW434252B (en) 1997-07-23 2001-05-16 Univ Georgia Res Found Process for the preparation of 2'-fluoro-5-methyl-β-L-arabino-furanosyluridine

Also Published As

Publication number Publication date
IN186807B (enExample) 2001-11-10
MY117314A (en) 2004-06-30
DE69831619T2 (de) 2006-06-14
EP0998482A1 (en) 2000-05-10
US20020062018A1 (en) 2002-05-23
EP0998482B1 (en) 2003-04-02
IL121730A (en) 2005-03-20
TR199701051A2 (xx) 1999-03-22
DK1327637T3 (da) 2006-01-16
DE69831619D1 (de) 2005-10-20
DE69812959T2 (de) 2004-03-04
BR9810804B1 (pt) 2012-01-10
TR199701051A3 (tr) 1999-03-22
KR100247505B1 (ko) 2000-03-15
ATE304547T1 (de) 2005-09-15
ATE236187T1 (de) 2003-04-15
CN1113892C (zh) 2003-07-09
US20030139593A1 (en) 2003-07-24
ES2249678T3 (es) 2006-04-01
CN1206012A (zh) 1999-01-27
AU8758298A (en) 1999-02-16
DE69812959D1 (de) 2003-05-08
TW434252B (en) 2001-05-16
PT998482E (pt) 2003-08-29
US6512107B2 (en) 2003-01-28
PT1327637E (pt) 2005-11-30
US6894159B2 (en) 2005-05-17
IL121730A0 (en) 1998-02-22
EP1327637B1 (en) 2005-09-14
WO1999005158A1 (en) 1999-02-04
WO1999005157A1 (en) 1999-02-04
KR19990013297A (ko) 1999-02-25
SA98180771B1 (ar) 2006-10-29
SI1327637T1 (sl) 2005-12-31
ID20624A (id) 1999-01-28
BR9810804A (pt) 2000-09-12
EP1327637A1 (en) 2003-07-16
ES2195370T3 (es) 2003-12-01

Similar Documents

Publication Publication Date Title
AR009092A1 (es) Un procedimiento para preparar 2'-fluoro-5-metil-beta-l- arabinofuranosiluridina.
NL960025I2 (nl) Gesubstitueerde 1,3-oxathiolanen met antivirale activiteit.
DE3877684D1 (de) Orthopaedischer operationstisch fuer glieder, insbesondere fuer unterste glieder.
WO1999064047A8 (en) Novel antiviral compounds
FI900752A0 (fi) Maskin foer automatisk montering av en elastisk taetning, i synnerhet en yttre taetning, i en foensterspringa.
DE69003574D1 (de) Hoeheneinstellvorrichtung, insbesondere fuer moebel.
FI910033A0 (fi) Laogmaettat, plastiskt universalfett med speciellt hydrogenerad delvis smaeltande fettkomponent.
FI914221A0 (fi) Tvaodelade, bundna polypropylen/ polyetylenfibrer.
ATE84534T1 (de) Antivirale tetrahydroimidazo(1,4>benzodiazepin-2- thione.
FI900113L (fi) Grundfaergloesa, vattenfasta laminater.
IT8919878A0 (it) Complesso di coperchio richiudibile, a tenuta ermetica.
FI912127L (fi) Effektivt delar utnyttjande, minnesbaserad funktionskrets med vaeljbara transmissionsegenskaper.
DE3772676D1 (de) Sackhalter, insbesondere fuer muellsaecke.
FI890857L (fi) Skaopenhet att placeras under arbetsbord, i synnerhet diskbord, i ett koek.
DE59100079D1 (de) Omnibus, insbesondere niederflurbus.
FI915959A7 (fi) Foerbraenningsmotormaskin, saerskilt dieselmotor.
DE68902227D1 (de) 2-(1h-imidazol-4(5)-yl)-3,4-dihydro-2h-1-benzothiopyran.
ES1038575Y (es) Mesa perfeccionada.
DE68903879D1 (de) Gaspedal, insbesondere fuer nutzfahrzeuge.
IT230196Y1 (it) Scooter, comprendente un ricettacolo per l'alloggiamento di un casco.
IT221657Z2 (it) Sedile ad elevata traspirabilita', ad esempio per autoveicoli.
ES1027994Y (es) Montaje de mesa, perfeccionado.
ES1010355Y (es) Mascarilla de quirofano, perfeccionada.
ES1025797Y (es) Nueva disposicion de peldaños, aplicable en escaleras desmontables.
FI922901L (fi) Foerstaerkare, med en utgaongsresonans- transformator.

Legal Events

Date Code Title Description
FG Grant, registration