AR005549A1 - Derivados de la 1-pirazol-3-iletil-4-indol-3-ilpiperidina, un procedimiento para prepararlos, medicamentos y preparaciones farmaceuticas que los contienen,un procedimiento para preparar las preparaciones farmaceuticas y empleo de los mismos para la preparacion de medicamentos. - Google Patents
Derivados de la 1-pirazol-3-iletil-4-indol-3-ilpiperidina, un procedimiento para prepararlos, medicamentos y preparaciones farmaceuticas que los contienen,un procedimiento para preparar las preparaciones farmaceuticas y empleo de los mismos para la preparacion de medicamentos.Info
- Publication number
- AR005549A1 AR005549A1 ARP970100297A ARP970100297A AR005549A1 AR 005549 A1 AR005549 A1 AR 005549A1 AR P970100297 A ARP970100297 A AR P970100297A AR P970100297 A ARP970100297 A AR P970100297A AR 005549 A1 AR005549 A1 AR 005549A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparations
- preparing
- procedure
- pharmaceutical preparations
- indol
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title 2
- 239000003814 drug Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 210000003169 central nervous system Anatomy 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- YLRRJIXSMHWUEC-UHFFFAOYSA-N 3-[1-[1-(1h-pyrazol-5-yl)ethyl]piperidin-4-yl]-1h-indole Chemical class C1CC(C=2C3=CC=CC=C3NC=2)CCN1C(C)C1=CC=NN1 YLRRJIXSMHWUEC-UHFFFAOYSA-N 0.000 abstract 1
- 230000004075 alteration Effects 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- MFOBKQAGVZYMON-UHFFFAOYSA-N cyanoformohydrazide Chemical compound NNC(=O)C#N MFOBKQAGVZYMON-UHFFFAOYSA-N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 230000007257 malfunction Effects 0.000 abstract 1
- -1 monosubstituted phenyl Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19602505A DE19602505A1 (de) | 1996-01-25 | 1996-01-25 | 1-(Pyrazol-4-Indol-3-yl)-Piperidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR005549A1 true AR005549A1 (es) | 1999-06-23 |
Family
ID=7783568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970100297A AR005549A1 (es) | 1996-01-25 | 1997-01-24 | Derivados de la 1-pirazol-3-iletil-4-indol-3-ilpiperidina, un procedimiento para prepararlos, medicamentos y preparaciones farmaceuticas que los contienen,un procedimiento para preparar las preparaciones farmaceuticas y empleo de los mismos para la preparacion de medicamentos. |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0879234A1 (cs) |
| JP (1) | JP2000503972A (cs) |
| KR (1) | KR19990081970A (cs) |
| CN (1) | CN1209807A (cs) |
| AR (1) | AR005549A1 (cs) |
| AU (1) | AU715785B2 (cs) |
| BR (1) | BR9707467A (cs) |
| CA (1) | CA2244136A1 (cs) |
| CZ (1) | CZ231898A3 (cs) |
| DE (1) | DE19602505A1 (cs) |
| HU (1) | HUP9900980A2 (cs) |
| NO (1) | NO983439L (cs) |
| PL (1) | PL328228A1 (cs) |
| SK (1) | SK99298A3 (cs) |
| WO (1) | WO1997027186A1 (cs) |
| ZA (1) | ZA97572B (cs) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001021614A1 (en) * | 1999-09-09 | 2001-03-29 | H. Lundbeck A/S | 5-aminoalkyl and 5-aminocarbonyl substituted indoles |
| CZ20021604A3 (cs) | 1999-11-10 | 2002-09-11 | Takeda Chemical Industries, Ltd. | Pětičlenné N-heterocyklické sloučeniny, farmaceutický přípravek a činidlo je obsahující a jejich použití |
| US7309703B2 (en) | 2000-08-14 | 2007-12-18 | Ortho Mcneil Pharmaceutical, Inc. | Substituted pyrazoles |
| US7332494B2 (en) | 2000-08-14 | 2008-02-19 | Janssen Pharmaceutica, N.V. | Method for treating allergies using substituted pyrazoles |
| US20050026927A1 (en) * | 2001-11-14 | 2005-02-03 | Henning Boettcher | Pyrazole derivatives as psychopharmaceuticals |
| BRPI0617204A2 (pt) | 2005-10-11 | 2011-07-19 | Hoffmann La Roche | derivados de imidazo benzodiazepina |
| EP1945213A4 (en) * | 2005-10-24 | 2009-12-02 | Janssen Pharmaceutica Nv | MODULATORS OF THE R3-PIPERIDINE-4-YL-INDOLE ORL-1 RECEPTOR |
| TWI548630B (zh) | 2011-04-06 | 2016-09-11 | Ｌｇ生命科學有限公司 | １－（３－氰基－１－異丙基－吲哚－５－基）吡唑－４－羧酸結晶型及其製造方法 |
| US20240000750A1 (en) * | 2020-11-04 | 2024-01-04 | Lg Chem, Ltd. | Method for preparing crystalline particles of 1-(3-cyano-1-isopropyl-indole-5-yl)pyrazole-4-carboxylic acid, and pharmaceutical composition comprising same |
| WO2025021120A1 (zh) * | 2023-07-24 | 2025-01-30 | 上海翊石医药科技有限公司 | 一类5-ht2a受体激动剂及其制备方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2060816C3 (de) * | 1970-12-10 | 1980-09-04 | Merck Patent Gmbh, 6100 Darmstadt | 4-Phenylpiperidinderivate Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen enthaltend diese Verbindungen |
| DE2258033A1 (de) * | 1972-11-27 | 1974-05-30 | Merck Patent Gmbh | Verfahren zur herstellung von pyrazolderivaten |
| GB8719167D0 (en) * | 1987-08-13 | 1987-09-23 | Glaxo Group Ltd | Chemical compounds |
| US5045550A (en) * | 1990-09-20 | 1991-09-03 | Warner-Lambert Co. | Substituted tetrahydropyridines as central nervous system agents |
| US5521196A (en) * | 1994-10-05 | 1996-05-28 | Eli Lilly And Company | 5-HT1F agonists for the treatment of migraine |
-
1996
- 1996-01-25 DE DE19602505A patent/DE19602505A1/de not_active Withdrawn
-
1997
- 1997-01-17 CN CN97191852A patent/CN1209807A/zh active Pending
- 1997-01-17 JP JP9526493A patent/JP2000503972A/ja active Pending
- 1997-01-17 SK SK992-98A patent/SK99298A3/sk unknown
- 1997-01-17 CZ CZ982318A patent/CZ231898A3/cs unknown
- 1997-01-17 HU HU9900980A patent/HUP9900980A2/hu unknown
- 1997-01-17 WO PCT/EP1997/000187 patent/WO1997027186A1/de not_active Application Discontinuation
- 1997-01-17 CA CA002244136A patent/CA2244136A1/en not_active Abandoned
- 1997-01-17 PL PL97328228A patent/PL328228A1/xx unknown
- 1997-01-17 KR KR1019980705688A patent/KR19990081970A/ko not_active Withdrawn
- 1997-01-17 AU AU14432/97A patent/AU715785B2/en not_active Ceased
- 1997-01-17 BR BR9707467A patent/BR9707467A/pt unknown
- 1997-01-17 EP EP97901049A patent/EP0879234A1/de not_active Withdrawn
- 1997-01-23 ZA ZA9700572A patent/ZA97572B/xx unknown
- 1997-01-24 AR ARP970100297A patent/AR005549A1/es unknown
-
1998
- 1998-07-24 NO NO983439A patent/NO983439L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR19990081970A (ko) | 1999-11-15 |
| CZ231898A3 (cs) | 1998-10-14 |
| NO983439D0 (no) | 1998-07-24 |
| ZA97572B (en) | 1997-08-04 |
| AU1443297A (en) | 1997-08-20 |
| CA2244136A1 (en) | 1997-07-31 |
| SK99298A3 (en) | 1999-01-11 |
| DE19602505A1 (de) | 1997-07-31 |
| NO983439L (no) | 1998-09-25 |
| PL328228A1 (en) | 1999-01-18 |
| BR9707467A (pt) | 1999-07-20 |
| WO1997027186A1 (de) | 1997-07-31 |
| HUP9900980A2 (hu) | 1999-07-28 |
| AU715785B2 (en) | 2000-02-10 |
| CN1209807A (zh) | 1999-03-03 |
| EP0879234A1 (de) | 1998-11-25 |
| JP2000503972A (ja) | 2000-04-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |