AR004226A1 - Disposicion para la administracion transmucosal de una droga en la cavidad oral. - Google Patents

Disposicion para la administracion transmucosal de una droga en la cavidad oral.

Info

Publication number
AR004226A1
AR004226A1 ARP960104864A ARP960104864A AR004226A1 AR 004226 A1 AR004226 A1 AR 004226A1 AR P960104864 A ARP960104864 A AR P960104864A AR P960104864 A ARP960104864 A AR P960104864A AR 004226 A1 AR004226 A1 AR 004226A1
Authority
AR
Argentina
Prior art keywords
drug
oral cavity
contact
transmucosal administration
tissue
Prior art date
Application number
ARP960104864A
Other languages
English (en)
Original Assignee
Theratech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theratech Inc filed Critical Theratech Inc
Publication of AR004226A1 publication Critical patent/AR004226A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Una disposición para la administración transmucosal de una droga en la cavidad oral que comprende una capa adhesiva que consiste un polímerohidrofílico que presenta una superficie adaptada para contactar un primer tejido de la cavidadoral y adherirse al mismo cuando está húmedo y unasuperficie opuesta en contacto con y adherido a una capa que contiene la droga portando una cantidad efectiva de una droga y opcionalmente una cantidadefectiva de un mejorador de penetración, endonde la capa que contiene la droga está adaptada para contactar y estar en relación de transferencia de drogacon el tejido de mucosa de la cavidad oral cuando la capa de adhesivo contacta y se adhiere al primer tejido. Las drogas preferidasincluyen péptid os talescomo los péptidos insulinotrópicos tipo glucagon.
ARP960104864A 1995-10-23 1996-10-23 Disposicion para la administracion transmucosal de una droga en la cavidad oral. AR004226A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/546,994 US5849322A (en) 1995-10-23 1995-10-23 Compositions and methods for buccal delivery of pharmaceutical agents

Publications (1)

Publication Number Publication Date
AR004226A1 true AR004226A1 (es) 1998-11-04

Family

ID=24182900

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960104864A AR004226A1 (es) 1995-10-23 1996-10-23 Disposicion para la administracion transmucosal de una droga en la cavidad oral.

Country Status (11)

Country Link
US (1) US5849322A (es)
EP (1) EP0857063A4 (es)
JP (1) JPH11513983A (es)
KR (1) KR19990064289A (es)
CN (1) CN1202821A (es)
AR (1) AR004226A1 (es)
AU (1) AU716054B2 (es)
BR (1) BR9611137A (es)
CA (1) CA2235402A1 (es)
WO (1) WO1997015297A1 (es)
ZA (1) ZA968907B (es)

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Also Published As

Publication number Publication date
EP0857063A4 (en) 2000-03-01
BR9611137A (pt) 1999-03-30
WO1997015297A1 (en) 1997-05-01
AU7464896A (en) 1997-05-15
AU716054B2 (en) 2000-02-17
EP0857063A1 (en) 1998-08-12
CA2235402A1 (en) 1997-05-01
JPH11513983A (ja) 1999-11-30
US5849322A (en) 1998-12-15
CN1202821A (zh) 1998-12-23
ZA968907B (en) 1997-06-12
KR19990064289A (ko) 1999-07-26

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