AR055412A1 - Preparacion farmaceutica adhesiva que contiene bisoprolol - Google Patents
Preparacion farmaceutica adhesiva que contiene bisoprololInfo
- Publication number
- AR055412A1 AR055412A1 ARP060103868A ARP060103868A AR055412A1 AR 055412 A1 AR055412 A1 AR 055412A1 AR P060103868 A ARP060103868 A AR P060103868A AR P060103868 A ARP060103868 A AR P060103868A AR 055412 A1 AR055412 A1 AR 055412A1
- Authority
- AR
- Argentina
- Prior art keywords
- bisoprolol
- adhesive
- preparation
- skin
- pharmaceutical preparation
- Prior art date
Links
- VHYCDWMUTMEGQY-UHFFFAOYSA-N bisoprolol Chemical compound CC(C)NCC(O)COC1=CC=C(COCCOC(C)C)C=C1 VHYCDWMUTMEGQY-UHFFFAOYSA-N 0.000 title abstract 6
- 229960002781 bisoprolol Drugs 0.000 title abstract 6
- 230000001070 adhesive effect Effects 0.000 title abstract 5
- 239000000853 adhesive Substances 0.000 title abstract 4
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 3
- 229920002367 Polyisobutene Polymers 0.000 abstract 2
- 239000012790 adhesive layer Substances 0.000 abstract 2
- 206010040880 Skin irritation Diseases 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 230000036556 skin irritation Effects 0.000 abstract 1
- 231100000475 skin irritation Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Preparacion farmacéutica adhesiva que cause menos irritacion a la superficie de la piel, mantenga una excelente estabilidad del bisoprolol en la preparacion y permita la administracion continua de una cantidad con eficacia farmacologica de bisoprolol en el organismo vivo. La preparacion adhesiva 10 comprende un soporte 1, una capa adhesiva 2 laminada sobre una superficie el soporte 1. La capa adhesiva 2 se caracteriza porque contiene bisoprolol, poliisobutileno, promotor de la pegajosidad, al igual que un ingrediente orgánico líquido compatible con el poliisobutileno y el promotor de la pegajosidad. De esta manera, se puede proporcionar una preparacion farmacéutica adhesiva que tiene buenas propiedades adhesivas, que provoca menos irritacion de la piel, que prácticamente no causa dolor en el momento del desprendimiento o retiro de la superficie de la piel y que no deja pasta. Del mismo modo, el bisoprolol se mantiene de manera altamente estable en la preparacion y se puede administrar en forma continua una cantidad con eficacia farmacologica de bisoprolol en el organismo vivo a través de la superficie de la piel.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005262559 | 2005-09-09 | ||
JP2006235270A JP5058531B2 (ja) | 2005-09-09 | 2006-08-31 | ビソプロロール含有貼付製剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR055412A1 true AR055412A1 (es) | 2007-08-22 |
Family
ID=37835896
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP060103868A AR055412A1 (es) | 2005-09-09 | 2006-09-06 | Preparacion farmaceutica adhesiva que contiene bisoprolol |
Country Status (15)
Country | Link |
---|---|
US (1) | US8808731B2 (es) |
EP (2) | EP1932523B1 (es) |
JP (1) | JP5058531B2 (es) |
KR (1) | KR101246400B1 (es) |
AR (1) | AR055412A1 (es) |
AU (1) | AU2006288260B2 (es) |
BR (1) | BRPI0615762A2 (es) |
CA (1) | CA2621867C (es) |
DK (1) | DK1932523T3 (es) |
IL (1) | IL189991A (es) |
NO (1) | NO20081253L (es) |
NZ (1) | NZ566494A (es) |
RU (1) | RU2396951C2 (es) |
TW (1) | TWI426930B (es) |
WO (1) | WO2007029781A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5058531B2 (ja) | 2005-09-09 | 2012-10-24 | 日東電工株式会社 | ビソプロロール含有貼付製剤 |
JP4945228B2 (ja) * | 2005-12-13 | 2012-06-06 | 日東電工株式会社 | ビソプロロール含有貼付製剤 |
JP5015562B2 (ja) * | 2005-12-13 | 2012-08-29 | 日東電工株式会社 | 貼付製剤 |
US8703178B2 (en) * | 2007-03-08 | 2014-04-22 | Nitto Denko Corporation | Percutaneous administration device of bisoprolol |
WO2009026133A2 (en) * | 2007-08-17 | 2009-02-26 | Alza Corporation | Transdermal bisoprolol delivery system |
US20110104247A1 (en) | 2008-03-25 | 2011-05-05 | Takeshi Ito | Composition for stabilizing beta-blocker and transdermally absorbable preparation comprising the same |
EP2286814B1 (en) * | 2008-05-15 | 2013-10-16 | Hisamitsu Pharmaceutical Co., Inc. | Transdermal preparation containing palonosetron |
US20100092544A1 (en) * | 2008-10-14 | 2010-04-15 | Katsuhiro Okada | Adhesive composition for patch and use thereof |
WO2010095537A1 (ja) | 2009-02-18 | 2010-08-26 | 久光製薬株式会社 | 経皮吸収製剤 |
KR101725832B1 (ko) | 2009-05-01 | 2017-04-11 | 히사미쓰 세이야꾸 가부시키가이샤 | 경피 흡수형 제제 |
JP5776079B2 (ja) * | 2010-02-26 | 2015-09-09 | 日東電工株式会社 | ビソプロロール含有貼付製剤 |
JP6318356B2 (ja) * | 2013-09-06 | 2018-05-09 | 日東電工株式会社 | ビソプロロール含有貼付製剤およびその包装体 |
JP6528154B2 (ja) * | 2013-09-06 | 2019-06-12 | 日東電工株式会社 | ビソプロロール含有貼付製剤 |
JP6318355B2 (ja) * | 2013-09-06 | 2018-05-09 | 日東電工株式会社 | ビソプロロール含有貼付製剤 |
JP2015051947A (ja) * | 2013-09-06 | 2015-03-19 | 日東電工株式会社 | ビソプロロール含有貼付製剤およびその包装体 |
WO2015133329A1 (ja) * | 2014-03-06 | 2015-09-11 | 帝國製薬株式会社 | 貼付製剤 |
CN107922805B (zh) * | 2015-08-17 | 2020-09-15 | 3M创新有限公司 | 纳米粘土填充的阻挡粘合剂组合物 |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5656286A (en) | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
JP2512565B2 (ja) * | 1989-10-13 | 1996-07-03 | 積水化学工業株式会社 | 貼付剤 |
US5508038A (en) | 1990-04-16 | 1996-04-16 | Alza Corporation | Polyisobutylene adhesives for transdermal devices |
US5149719A (en) * | 1990-04-27 | 1992-09-22 | Minnesota Mining And Manufacturing Company | Composition for transdermal penetration of medicaments |
JPH0813956B2 (ja) | 1990-06-22 | 1996-02-14 | 積水化学工業株式会社 | 表面保護フィルムの製造方法 |
JP3355671B2 (ja) | 1992-11-09 | 2002-12-09 | 旭化成株式会社 | 粘接着剤用組成物 |
JPH07330591A (ja) | 1994-06-06 | 1995-12-19 | Kanegafuchi Chem Ind Co Ltd | 経皮吸収製剤 |
DE19512181C2 (de) * | 1995-03-31 | 2003-11-06 | Hexal Pharma Gmbh | Transdermales System mit Ramipril und/oder Trandolapril als ACE-Hemmer |
NZ309980A (en) | 1995-06-07 | 2001-06-29 | Noven Pharma | Transdermal composition containing a blend of one or more polymers, one or more drugs that has a low molecular weight and is liquid at room temperature |
JPH10152434A (ja) * | 1996-09-26 | 1998-06-09 | Nitto Denko Corp | 経皮吸収型製剤 |
JP4119502B2 (ja) | 1997-07-08 | 2008-07-16 | 埼玉第一製薬株式会社 | 新規な経皮吸収促進剤を含有する外用剤組成物 |
JP3930984B2 (ja) * | 1997-12-12 | 2007-06-13 | 日東電工株式会社 | 経皮吸収型製剤 |
US20040142024A1 (en) * | 1999-07-27 | 2004-07-22 | Hisamitsu Pharmaceutical Co., Inc. | Patch formulation for external use |
ATE353636T1 (de) * | 1999-12-15 | 2007-03-15 | Hisamitsu Pharmaceutical Co | Adhäsive zubereitungen |
FR2807323A1 (fr) * | 2000-04-10 | 2001-10-12 | Oreal | Composition, notamment cosmetique, renfermant un steroide et un 2-alkyl alcanol ou un ester |
DE10033853A1 (de) | 2000-07-12 | 2002-01-31 | Hexal Ag | Transdermales therapeutisches System mit hochdispersem Siliziumdioxid |
JP2002038114A (ja) | 2000-07-26 | 2002-02-06 | Aicello Chemical Co Ltd | 粘着付与マスターバッチ及びこれを用いた粘着フィルム |
JP4358978B2 (ja) * | 2000-09-05 | 2009-11-04 | 日東電工株式会社 | 経皮吸収製剤 |
JP2002187836A (ja) * | 2000-12-21 | 2002-07-05 | Oishi Koseido:Kk | 貼付剤 |
JP4478757B2 (ja) * | 2002-04-19 | 2010-06-09 | 日東電工株式会社 | ビソプロロール含有貼付剤 |
JP2004244585A (ja) | 2003-02-17 | 2004-09-02 | Nippon Shokubai Co Ltd | 粘着剤組成物および粘着製品 |
EP1652508B1 (en) * | 2003-07-31 | 2013-12-04 | Hisamitsu Pharmaceutical Co., Inc. | Adhesive patch |
US20070158227A1 (en) * | 2004-01-30 | 2007-07-12 | Satoshi Amano | Plaster enclosing packaging bag |
DE202005006418U1 (de) | 2004-04-23 | 2005-09-08 | Infocus Corp., Wilsonville | Anordnung von lichtaussendenden Einrichtungen in Projektionssystemen |
JP4745747B2 (ja) | 2004-08-12 | 2011-08-10 | 日東電工株式会社 | フェンタニル含有貼付製剤 |
ES2596809T3 (es) | 2004-10-08 | 2017-01-12 | Noven Pharmaceuticals, Inc. | Dispositivo de administración transdérmica de fármacos que incluye un refuerzo oclusivo |
JP5632577B2 (ja) | 2005-01-31 | 2014-11-26 | 久光製薬株式会社 | 貼付剤 |
JP4782438B2 (ja) | 2005-02-17 | 2011-09-28 | 日東電工株式会社 | 貼付製剤 |
JP5058531B2 (ja) | 2005-09-09 | 2012-10-24 | 日東電工株式会社 | ビソプロロール含有貼付製剤 |
JP5015562B2 (ja) * | 2005-12-13 | 2012-08-29 | 日東電工株式会社 | 貼付製剤 |
JP4945228B2 (ja) | 2005-12-13 | 2012-06-06 | 日東電工株式会社 | ビソプロロール含有貼付製剤 |
US8703178B2 (en) * | 2007-03-08 | 2014-04-22 | Nitto Denko Corporation | Percutaneous administration device of bisoprolol |
-
2006
- 2006-08-31 JP JP2006235270A patent/JP5058531B2/ja active Active
- 2006-09-06 AR ARP060103868A patent/AR055412A1/es not_active Application Discontinuation
- 2006-09-07 EP EP06783221A patent/EP1932523B1/en not_active Not-in-force
- 2006-09-07 BR BRPI0615762-9A patent/BRPI0615762A2/pt not_active IP Right Cessation
- 2006-09-07 RU RU2008113846/15A patent/RU2396951C2/ru not_active IP Right Cessation
- 2006-09-07 EP EP11003489A patent/EP2359823A1/en not_active Withdrawn
- 2006-09-07 US US12/066,095 patent/US8808731B2/en not_active Expired - Fee Related
- 2006-09-07 WO PCT/JP2006/317764 patent/WO2007029781A1/ja active Application Filing
- 2006-09-07 NZ NZ566494A patent/NZ566494A/en not_active IP Right Cessation
- 2006-09-07 DK DK06783221.2T patent/DK1932523T3/da active
- 2006-09-07 KR KR1020087005702A patent/KR101246400B1/ko not_active IP Right Cessation
- 2006-09-07 CA CA2621867A patent/CA2621867C/en not_active Expired - Fee Related
- 2006-09-07 AU AU2006288260A patent/AU2006288260B2/en not_active Ceased
- 2006-09-08 TW TW095133239A patent/TWI426930B/zh not_active IP Right Cessation
-
2008
- 2008-03-06 IL IL189991A patent/IL189991A/en not_active IP Right Cessation
- 2008-03-10 NO NO20081253A patent/NO20081253L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US20090291126A1 (en) | 2009-11-26 |
IL189991A (en) | 2014-07-31 |
NO20081253L (no) | 2008-06-09 |
KR20080041692A (ko) | 2008-05-13 |
EP1932523A4 (en) | 2008-11-26 |
EP2359823A1 (en) | 2011-08-24 |
EP1932523B1 (en) | 2011-07-27 |
AU2006288260A1 (en) | 2007-03-15 |
RU2008113846A (ru) | 2009-10-20 |
US8808731B2 (en) | 2014-08-19 |
CA2621867C (en) | 2012-12-18 |
KR101246400B1 (ko) | 2013-03-21 |
JP2007099759A (ja) | 2007-04-19 |
AU2006288260B2 (en) | 2011-05-26 |
NZ566494A (en) | 2010-10-29 |
EP1932523A1 (en) | 2008-06-18 |
TW200800144A (en) | 2008-01-01 |
CA2621867A1 (en) | 2007-03-15 |
DK1932523T3 (da) | 2011-11-14 |
WO2007029781A1 (ja) | 2007-03-15 |
IL189991A0 (en) | 2008-08-07 |
TWI426930B (zh) | 2014-02-21 |
JP5058531B2 (ja) | 2012-10-24 |
RU2396951C2 (ru) | 2010-08-20 |
BRPI0615762A2 (pt) | 2011-05-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |