AP518A - Spirostanyl glycosidal crystalline monohydrate. - Google Patents

Spirostanyl glycosidal crystalline monohydrate. Download PDF

Info

Publication number
AP518A
AP518A APAP/P/1994/000615A AP9400615A AP518A AP 518 A AP518 A AP 518A AP 9400615 A AP9400615 A AP 9400615A AP 518 A AP518 A AP 518A
Authority
AP
ARIPO
Prior art keywords
crystalline
compound
water
monohydrate
hypercholesterolemia
Prior art date
Application number
APAP/P/1994/000615A
Other languages
English (en)
Other versions
AP9400615A0 (en
Inventor
Douglas John Meldrum Allen
Jr Harry A Watson
Jonothan B Zung
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of AP9400615A0 publication Critical patent/AP9400615A0/xx
Application granted granted Critical
Publication of AP518A publication Critical patent/AP518A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
APAP/P/1994/000615A 1993-04-28 1994-01-27 Spirostanyl glycosidal crystalline monohydrate. AP518A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5444993A 1993-04-28 1993-04-28

Publications (2)

Publication Number Publication Date
AP9400615A0 AP9400615A0 (en) 1994-01-31
AP518A true AP518A (en) 1996-08-23

Family

ID=21991141

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1994/000615A AP518A (en) 1993-04-28 1994-01-27 Spirostanyl glycosidal crystalline monohydrate.

Country Status (23)

Country Link
US (1) US5760009A (no)
EP (1) EP0696292A1 (no)
JP (1) JPH08504830A (no)
CN (1) CN1121722A (no)
AP (1) AP518A (no)
AU (1) AU6295694A (no)
BG (1) BG100098A (no)
BR (1) BR9406332A (no)
CA (1) CA2161239A1 (no)
CZ (1) CZ280195A3 (no)
FI (1) FI941942A (no)
HU (1) HUT67142A (no)
IL (1) IL109374A0 (no)
LV (1) LV11475A (no)
MA (1) MA23179A1 (no)
NO (1) NO954322D0 (no)
OA (1) OA10715A (no)
PL (1) PL311278A1 (no)
SI (1) SI9400203A (no)
SK (1) SK135195A3 (no)
WO (1) WO1994025479A1 (no)
YU (1) YU22694A (no)
ZA (1) ZA942772B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2074006B1 (es) * 1993-07-05 1996-03-16 Pfizer Glicosidos esteroidales para tratar hipercolesterolemia.
WO1996038466A1 (en) * 1995-05-29 1996-12-05 Pfizer Inc. Steroidal glycosides
GB9923076D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
KR20070117001A (ko) * 1998-03-26 2007-12-11 파이토팜 피엘씨 알츠하이머병을 치료하기 위한 스밀라게닌 및안주로게닌-ｄ
GB9923078D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
US6343258B1 (en) 1999-08-13 2002-01-29 ALEXIS Brian Method for testing for readiness for harvesting of tribulus terrestris l. having high steroidal saponin content
GB9923077D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB0000228D0 (en) * 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
US6410520B2 (en) 2000-02-01 2002-06-25 The Procter & Gamble Company Selective crystallization of 3-pyridyl-1-hydroxyethylidene-1, 1-bisphosphonic acid sodium as the hemipentahydrate or monohydrate
US6562974B2 (en) 2000-02-01 2003-05-13 The Procter & Gamble Company Process for making geminal bisphosphonates
GB0107822D0 (en) * 2001-03-28 2001-05-23 Phytopharm Plc Sapogenin derivatives their synthesis and use methods based upon their use
US6825960B2 (en) * 2002-01-15 2004-11-30 Inphase Technologies, Inc. System and method for bitwise readout holographic ROM
US20050130948A1 (en) * 2002-03-27 2005-06-16 Daryl Rees Therapeutic methods and uses of sapogenins and their derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2926463A1 (de) * 1978-07-05 1980-01-24 Roecar Holdings Nv Spiroketaline und ihre verwendung
US4260603A (en) * 1979-01-02 1981-04-07 Pegel Karl H Sterol glycoside with activity as prostaglandin synthetase inhibitor
NZ193564A (en) * 1979-05-02 1985-01-31 Aruba Pty Ltd Steroid alkaloids from solanum sodomeum and pharmaceutical compositions
JPS56120700A (en) * 1980-02-26 1981-09-22 Wakunaga Yakuhin Kk Cardiac stimmulant
US4602003A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia
US4602005A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis
US5010185A (en) * 1989-06-13 1991-04-23 Pfizer Inc. Processes for tigogenin beta-cellobioside
WO1993007167A1 (en) * 1991-10-04 1993-04-15 The Procter & Gamble Company Cholesterol lowering compounds and process for making them
EP0619822A1 (en) * 1991-11-25 1994-10-19 Pfizer Inc. Method for making steroidal peracyl glycosides
JPH07504921A (ja) * 1992-06-26 1995-06-01 フアイザー・インコーポレイテツド 高コレステロール血症を治療するためのステロイドグリコシド
US5530107A (en) * 1992-10-15 1996-06-25 Pfizer Inc. Method for making steroidal peracyl glycosides
JP2767530B2 (ja) * 1993-05-06 1998-06-18 花王株式会社 物品の集荷方法及び装置

Also Published As

Publication number Publication date
WO1994025479A1 (en) 1994-11-10
HU9401209D0 (en) 1994-08-29
AP9400615A0 (en) 1994-01-31
BG100098A (bg) 1996-04-30
FI941942A (fi) 1994-10-29
CZ280195A3 (en) 1996-02-14
MA23179A1 (fr) 1994-12-31
YU22694A (sh) 1997-03-07
SK135195A3 (en) 1996-03-06
EP0696292A1 (en) 1996-02-14
JPH08504830A (ja) 1996-05-28
CA2161239A1 (en) 1994-11-10
BR9406332A (pt) 1995-12-26
ZA942772B (en) 1995-10-23
LV11475A (lv) 1996-08-20
OA10715A (en) 2002-12-09
CN1121722A (zh) 1996-05-01
NO954322L (no) 1995-10-27
NO954322D0 (no) 1995-10-27
IL109374A0 (en) 1994-07-31
SI9400203A (en) 1995-06-30
US5760009A (en) 1998-06-02
AU6295694A (en) 1994-11-21
PL311278A1 (en) 1996-02-05
HUT67142A (en) 1995-02-28
FI941942A0 (fi) 1994-04-27

Similar Documents

Publication Publication Date Title
US5703052A (en) Sterodial glycosides for treating hypercholesterolemia
AP518A (en) Spirostanyl glycosidal crystalline monohydrate.
KR970002642B1 (ko) 안드로스탄 17-카복실산 에스테르, 이의 제조방법, 및 이를 함유하는 약제
GB1599863A (en) Pharmaceutical compositions for use in the inhibition of the biosynthesis of mevalonic acid
GB2068382A (en) 25-hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol
US4332797A (en) Chlorambucil derivatives
US6150336A (en) Steroidal glycosides
US5804562A (en) Spirostanyl glycosidal crystals
DD266801A5 (de) Verfahren zur herstellung einer oestrogen wirksamen verbindung
CA1255293A (en) 2-oxa- or -aza-pregnane compounds
EP0430386A1 (de) 14Alpha, 17alpha-überbrückte 16-Hydroxyestratriene
JPS635097A (ja) アンドロスト−４−エン−３，１７−ジオンのメチレン誘導体およびその製造方法
KR20030090207A (ko) 결장표적성 프로드럭으로서의 코티코스테로이드21-설페이트 소듐 유도체
HU181845B (en) Process for producing delta-4,9 above-pregnane derivatives
NO945001L (no) Steroide glykosider for behandling av hyperkolestrolemi