OA10715A - Spirostanyl glycosidal crystalline monohydrate - Google Patents

Spirostanyl glycosidal crystalline monohydrate Download PDF

Info

Publication number
OA10715A
OA10715A OA60729A OA60729A OA10715A OA 10715 A OA10715 A OA 10715A OA 60729 A OA60729 A OA 60729A OA 60729 A OA60729 A OA 60729A OA 10715 A OA10715 A OA 10715A
Authority
OA
OAPI
Prior art keywords
crystalline
glycoside
monohydrate
pct
ray diffraction
Prior art date
Application number
OA60729A
Other languages
English (en)
Inventor
Douglas J M Allen
Watson Harry A Jr
Jonathan B Zung
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of OA10715A publication Critical patent/OA10715A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
OA60729A 1993-04-28 1995-10-27 Spirostanyl glycosidal crystalline monohydrate OA10715A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5444993A 1993-04-28 1993-04-28

Publications (1)

Publication Number Publication Date
OA10715A true OA10715A (en) 2002-12-09

Family

ID=21991141

Family Applications (1)

Application Number Title Priority Date Filing Date
OA60729A OA10715A (en) 1993-04-28 1995-10-27 Spirostanyl glycosidal crystalline monohydrate

Country Status (23)

Country Link
US (1) US5760009A (no)
EP (1) EP0696292A1 (no)
JP (1) JPH08504830A (no)
CN (1) CN1121722A (no)
AP (1) AP518A (no)
AU (1) AU6295694A (no)
BG (1) BG100098A (no)
BR (1) BR9406332A (no)
CA (1) CA2161239A1 (no)
CZ (1) CZ280195A3 (no)
FI (1) FI941942A (no)
HU (1) HUT67142A (no)
IL (1) IL109374A0 (no)
LV (1) LV11475A (no)
MA (1) MA23179A1 (no)
NO (1) NO954322D0 (no)
OA (1) OA10715A (no)
PL (1) PL311278A1 (no)
SI (1) SI9400203A (no)
SK (1) SK135195A3 (no)
WO (1) WO1994025479A1 (no)
YU (1) YU22694A (no)
ZA (1) ZA942772B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2074006B1 (es) * 1993-07-05 1996-03-16 Pfizer Glicosidos esteroidales para tratar hipercolesterolemia.
WO1996038466A1 (en) * 1995-05-29 1996-12-05 Pfizer Inc. Steroidal glycosides
GB9923076D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
KR20070117001A (ko) * 1998-03-26 2007-12-11 파이토팜 피엘씨 알츠하이머병을 치료하기 위한 스밀라게닌 및안주로게닌-ｄ
GB9923078D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
US6343258B1 (en) 1999-08-13 2002-01-29 ALEXIS Brian Method for testing for readiness for harvesting of tribulus terrestris l. having high steroidal saponin content
GB9923077D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB0000228D0 (en) * 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
US6410520B2 (en) 2000-02-01 2002-06-25 The Procter & Gamble Company Selective crystallization of 3-pyridyl-1-hydroxyethylidene-1, 1-bisphosphonic acid sodium as the hemipentahydrate or monohydrate
US6562974B2 (en) 2000-02-01 2003-05-13 The Procter & Gamble Company Process for making geminal bisphosphonates
GB0107822D0 (en) * 2001-03-28 2001-05-23 Phytopharm Plc Sapogenin derivatives their synthesis and use methods based upon their use
US6825960B2 (en) * 2002-01-15 2004-11-30 Inphase Technologies, Inc. System and method for bitwise readout holographic ROM
US20050130948A1 (en) * 2002-03-27 2005-06-16 Daryl Rees Therapeutic methods and uses of sapogenins and their derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2926463A1 (de) * 1978-07-05 1980-01-24 Roecar Holdings Nv Spiroketaline und ihre verwendung
US4260603A (en) * 1979-01-02 1981-04-07 Pegel Karl H Sterol glycoside with activity as prostaglandin synthetase inhibitor
NZ193564A (en) * 1979-05-02 1985-01-31 Aruba Pty Ltd Steroid alkaloids from solanum sodomeum and pharmaceutical compositions
JPS56120700A (en) * 1980-02-26 1981-09-22 Wakunaga Yakuhin Kk Cardiac stimmulant
US4602003A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia
US4602005A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis
US5010185A (en) * 1989-06-13 1991-04-23 Pfizer Inc. Processes for tigogenin beta-cellobioside
WO1993007167A1 (en) * 1991-10-04 1993-04-15 The Procter & Gamble Company Cholesterol lowering compounds and process for making them
EP0619822A1 (en) * 1991-11-25 1994-10-19 Pfizer Inc. Method for making steroidal peracyl glycosides
JPH07504921A (ja) * 1992-06-26 1995-06-01 フアイザー・インコーポレイテツド 高コレステロール血症を治療するためのステロイドグリコシド
US5530107A (en) * 1992-10-15 1996-06-25 Pfizer Inc. Method for making steroidal peracyl glycosides
JP2767530B2 (ja) * 1993-05-06 1998-06-18 花王株式会社 物品の集荷方法及び装置

Also Published As

Publication number Publication date
WO1994025479A1 (en) 1994-11-10
HU9401209D0 (en) 1994-08-29
AP9400615A0 (en) 1994-01-31
BG100098A (bg) 1996-04-30
FI941942A (fi) 1994-10-29
AP518A (en) 1996-08-23
CZ280195A3 (en) 1996-02-14
MA23179A1 (fr) 1994-12-31
YU22694A (sh) 1997-03-07
SK135195A3 (en) 1996-03-06
EP0696292A1 (en) 1996-02-14
JPH08504830A (ja) 1996-05-28
CA2161239A1 (en) 1994-11-10
BR9406332A (pt) 1995-12-26
ZA942772B (en) 1995-10-23
LV11475A (lv) 1996-08-20
CN1121722A (zh) 1996-05-01
NO954322L (no) 1995-10-27
NO954322D0 (no) 1995-10-27
IL109374A0 (en) 1994-07-31
SI9400203A (en) 1995-06-30
US5760009A (en) 1998-06-02
AU6295694A (en) 1994-11-21
PL311278A1 (en) 1996-02-05
HUT67142A (en) 1995-02-28
FI941942A0 (fi) 1994-04-27

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