AP365A - Novel steroid esters. - Google Patents

Novel steroid esters. Download PDF

Info

Publication number
AP365A
AP365A APAP/P/1992/000354A AP9200354A AP365A AP 365 A AP365 A AP 365A AP 9200354 A AP9200354 A AP 9200354A AP 365 A AP365 A AP 365A
Authority
AP
ARIPO
Prior art keywords
hydrogen
compound
carbon atoms
dione
formula
Prior art date
Application number
APAP/P/1992/000354A
Other languages
English (en)
Other versions
AP9200354A0 (en
Inventor
Bengt Ingemar Axelsson
Ralph Lennart Brattsand
Leif Arne Kallstorm
Bror Arne Thalen
Original Assignee
Ab Astra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ab Astra filed Critical Ab Astra
Publication of AP9200354A0 publication Critical patent/AP9200354A0/xx
Application granted granted Critical
Publication of AP365A publication Critical patent/AP365A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
APAP/P/1992/000354A 1991-02-04 1992-01-27 Novel steroid esters. AP365A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9100342A SE9100342D0 (sv) 1991-02-04 1991-02-04 Novel steroid esters

Publications (2)

Publication Number Publication Date
AP9200354A0 AP9200354A0 (en) 1992-01-31
AP365A true AP365A (en) 1994-10-21

Family

ID=20381807

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1992/000354A AP365A (en) 1991-02-04 1992-01-27 Novel steroid esters.

Country Status (38)

Country Link
US (1) US5614514A (fr)
EP (1) EP0572451B1 (fr)
JP (1) JP2947933B2 (fr)
KR (1) KR100205835B1 (fr)
CN (3) CN1039329C (fr)
AP (1) AP365A (fr)
AT (1) ATE164589T1 (fr)
BG (1) BG61816B1 (fr)
CA (1) CA2100453A1 (fr)
CZ (1) CZ282057B6 (fr)
DE (1) DE69224982T2 (fr)
DK (1) DK0572451T3 (fr)
DZ (1) DZ1554A1 (fr)
EE (1) EE03110B1 (fr)
ES (1) ES2114931T3 (fr)
FI (1) FI933451A0 (fr)
HK (1) HK1004335A1 (fr)
HU (1) HU221168B1 (fr)
IE (1) IE920167A1 (fr)
IL (1) IL100542A (fr)
IS (1) IS1653B (fr)
MA (1) MA22407A1 (fr)
MX (1) MX9200374A (fr)
MY (1) MY111502A (fr)
NO (1) NO304074B1 (fr)
NZ (1) NZ241211A (fr)
PL (1) PL170383B1 (fr)
PT (1) PT100087B (fr)
RO (1) RO111272B1 (fr)
RU (1) RU2112775C1 (fr)
SE (1) SE9100342D0 (fr)
SK (1) SK281802B6 (fr)
TN (1) TNSN92008A1 (fr)
TW (1) TW287166B (fr)
UA (1) UA43825C2 (fr)
WO (1) WO1992013873A1 (fr)
YU (1) YU48893B (fr)
ZA (1) ZA92234B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
KR960700266A (ko) * 1993-01-08 1996-01-19 클래스 빌헬름슨 신규 결장- 또는 회장-특이성 스테로이드 유도체(Novel Colon-or lleum-Specific Steroid Derivatives)
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
US5983956A (en) 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
GB9923076D0 (en) 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
EP1079859B1 (fr) 1998-05-22 2010-07-14 The Board Of Trustees Of The Leland Stanford Junior University Molecules bifonctionnelles et therapies basees sur celles-ci
IL146132A0 (en) 1999-05-27 2002-07-25 Euro Celtique Sa Preparations for the application of anti-infective and/or anti-inflammatory agents to external or internal parts of the human or animal body in functional and cosmetic tissue remodelling and repair treatments
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
HRP20010018A2 (en) 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
WO2003070745A2 (fr) * 2002-02-20 2003-08-28 Sepracor Inc. Formes modifiees de carbonate et de carbamate de glucocorticoides
US20050009798A1 (en) 2002-02-20 2005-01-13 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists
PL374731A1 (en) 2002-07-08 2005-10-31 Pliva-Istrazivacki Institut D.O.O. New compounds, compositions and methods for treatment of inflammatory diseases and conditions
RS20050006A (en) 2002-07-08 2007-09-21 Glaxo Smith Kline Istraživački Centar Zagreb D.O.O., Novel compounds,compositions as carriers for steroid/non- steroid anti-inflammatory,antineoplastic and antiviral active molecules
WO2004017904A2 (fr) * 2002-08-23 2004-03-04 The Mclean Hospital Corporation Conjugues de corticosteroides et utilisations de ceux-ci
WO2004033478A2 (fr) * 2002-10-08 2004-04-22 Sepracor Inc. Formes modifiees par l'acide gras des glucocorticoides
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
HRP20030604A2 (en) 2003-07-25 2005-04-30 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromenes, preparation thereof andtheir antiinflammatory action
HRP20030603A2 (en) 2003-07-25 2005-10-31 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromene compounds of antiinflammatory action
WO2005016352A1 (fr) * 2003-08-05 2005-02-24 Sepracor Inc. Amino-acide et formes de glucocorticoide modifiees par peptide associes a des agonistes beta 2-adrenergiques
US20090048221A1 (en) 2004-10-27 2009-02-19 Mladen Mercep Conjugates with Anti-Inflammatory Activity
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
DK2398500T3 (da) 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
US8737506B1 (en) 2010-12-29 2014-05-27 Sprint Communications Company L.P. Determination of transmit diversity transmission delays
US8437713B1 (en) 2011-02-16 2013-05-07 Sprint Communications Company L.P. Wireless transmit diversity control by location of a wireless communication device
US8565686B2 (en) 2011-06-30 2013-10-22 Sprint Communications Company L.P. Power status multipath search window sizing for wireless communications
IN2014MN01571A (fr) 2012-02-10 2015-05-15 Taiwan Liposome Co Ltd
JP5965187B2 (ja) * 2012-03-30 2016-08-03 小林製薬株式会社 油性軟膏剤
CN109985048B (zh) * 2017-12-29 2021-06-29 广州市赛普特医药科技股份有限公司 2β,3α,5α-三羟基雄甾-6-酮用于炎症反应的治疗

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0170642A2 (fr) * 1984-07-30 1986-02-05 Aktiebolaget Draco Liposomes contenant des esters de stéroides
US4695625A (en) * 1984-06-11 1987-09-22 Sicor Societa Italiana Corticosteroidi S.P.A. Process for the preparation of 16,17 acetals of pregnane derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126375A (en) * 1964-03-24 Chioacyl
US3197469A (en) * 1958-08-06 1965-07-27 Pharmaceutical Res Products In 16, 17-acetals and ketals of 6-halo-16, 17-dihydroxy steroids of the pregnane seriesand intermediates therefor
US3048581A (en) * 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
US3357974A (en) * 1965-12-28 1967-12-12 Merck & Co Inc Processes for preparing 16alpha, 17alpha-acetals and ketals of 16alpha, 17alpha, 21-trihydroxy-delta4-pregnene-3, 20-diones
US3758686A (en) * 1971-12-07 1973-09-11 American Cyanamid Co Method of using steroid acetonides
SE378109B (fr) * 1972-05-19 1975-08-18 Bofors Ab
US3796701A (en) * 1973-02-26 1974-03-12 Squibb & Sons Inc 5alpha,9-oxazino steroids and 9-carboxamido steroids
SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
US4304727A (en) * 1980-12-05 1981-12-08 The Upjohn Company 9α-Debromination
JPS58176485A (ja) * 1982-04-08 1983-10-15 Nippon Denso Co Ltd 可変容量圧縮機
US4749649A (en) * 1983-05-16 1988-06-07 The Upjohn Company Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen
JPS6067496A (ja) * 1983-09-26 1985-04-17 Ota Seiyaku Kk フルオシノロン１６，１７−アセトニド２１−ブチレ−トおよびその製造法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695625A (en) * 1984-06-11 1987-09-22 Sicor Societa Italiana Corticosteroidi S.P.A. Process for the preparation of 16,17 acetals of pregnane derivatives
EP0170642A2 (fr) * 1984-07-30 1986-02-05 Aktiebolaget Draco Liposomes contenant des esters de stéroides

Also Published As

Publication number Publication date
CN1158726A (zh) 1997-09-10
JP2947933B2 (ja) 1999-09-13
TNSN92008A1 (fr) 1993-06-08
NZ241211A (en) 1993-08-26
CZ282057B6 (cs) 1997-05-14
DZ1554A1 (fr) 2002-02-17
DE69224982D1 (de) 1998-05-07
WO1992013873A1 (fr) 1992-08-20
NO304074B1 (no) 1998-10-19
YU48893B (sh) 2002-10-18
MA22407A1 (fr) 1992-10-01
AP9200354A0 (en) 1992-01-31
IS3809A (is) 1992-08-05
EE03110B1 (et) 1998-08-17
BG98011A (bg) 1994-04-29
FI933451A (fi) 1993-08-03
DE69224982T2 (de) 1998-07-30
EP0572451A1 (fr) 1993-12-08
ES2114931T3 (es) 1998-06-16
MY111502A (en) 2000-07-31
UA43825C2 (uk) 2002-01-15
HK1004335A1 (en) 1998-11-20
RO111272B1 (ro) 1996-08-30
NO932762D0 (no) 1993-08-02
PT100087B (pt) 1999-09-30
ZA92234B (en) 1992-10-28
IL100542A (en) 1997-02-18
CN1076606C (zh) 2001-12-26
HU221168B1 (en) 2002-08-28
ATE164589T1 (de) 1998-04-15
BG61816B1 (bg) 1998-06-30
CZ149593A3 (en) 1994-03-16
US5614514A (en) 1997-03-25
TW287166B (fr) 1996-10-01
SK79793A3 (en) 1994-03-09
SK281802B6 (sk) 2001-08-06
IL100542A0 (en) 1992-09-06
HU9302243D0 (en) 1993-10-28
CA2100453A1 (fr) 1992-08-05
YU6492A (sh) 1994-12-28
CN1039329C (zh) 1998-07-29
SE9100342D0 (sv) 1991-02-04
JPH06505233A (ja) 1994-06-16
CN1076607C (zh) 2001-12-26
CN1155418A (zh) 1997-07-30
CN1064078A (zh) 1992-09-02
PL170383B1 (pl) 1996-12-31
HUT64972A (en) 1994-03-28
IE920167A1 (en) 1992-08-12
PT100087A (pt) 1993-05-31
MX9200374A (es) 1992-08-01
AU661472B2 (en) 1995-07-27
FI933451A0 (fi) 1993-08-03
DK0572451T3 (da) 1998-10-19
NO932762L (no) 1993-08-02
RU2112775C1 (ru) 1998-06-10
IS1653B (is) 1997-06-20
EP0572451B1 (fr) 1998-04-01
AU1235892A (en) 1992-09-07
KR100205835B1 (ko) 1999-07-01

Similar Documents

Publication Publication Date Title
AP365A (en) Novel steroid esters.
EP0570454B1 (fr) Nouveaux steroides
US4693999A (en) Liposomes containing steroid esters
US5888995A (en) Steroid esters
AU661472C (en) Novel steroid esters
SI9210064A (sl) Nove antiinflamatorno in antialergijsko aktivne spojine, glukokortikosteroidi ter postopki za njihovo pripravo
AU661471C (en) Novel steroids
HRP920587A2 (en) Liposomes containing steroid esters a process for the preparation of stable camomile extract rich with active substances