AP3589A - A novel 1,2,3,4-tetrahydroquinoline derivative useful for the treatment of diabetes - Google Patents

A novel 1,2,3,4-tetrahydroquinoline derivative useful for the treatment of diabetes

Info

Publication number
AP3589A
AP3589A AP2014007436A AP2014007436A AP3589A AP 3589 A AP3589 A AP 3589A AP 2014007436 A AP2014007436 A AP 2014007436A AP 2014007436 A AP2014007436 A AP 2014007436A AP 3589 A AP3589 A AP 3589A
Authority
AP
ARIPO
Prior art keywords
diabetes
novel
treatment
derivative useful
tetrahydroquinoline derivative
Prior art date
Application number
AP2014007436A
Other languages
English (en)
Other versions
AP2014007436A0 (en
Inventor
Chafiq Hamdouchi
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46690732&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP3589(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of AP2014007436A0 publication Critical patent/AP2014007436A0/xx
Application granted granted Critical
Publication of AP3589A publication Critical patent/AP3589A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AP2014007436A 2011-08-17 2012-08-09 A novel 1,2,3,4-tetrahydroquinoline derivative useful for the treatment of diabetes AP3589A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161524462P 2011-08-17 2011-08-17
PCT/US2012/050051 WO2013025424A1 (en) 2011-08-17 2012-08-09 A Novel 1,2,3,4-Tetrahydroquinoline Derivative Useful for the Treatment of Diabetes

Publications (2)

Publication Number Publication Date
AP2014007436A0 AP2014007436A0 (en) 2014-02-28
AP3589A true AP3589A (en) 2016-02-15

Family

ID=46690732

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2014007436A AP3589A (en) 2011-08-17 2012-08-09 A novel 1,2,3,4-tetrahydroquinoline derivative useful for the treatment of diabetes

Country Status (29)

Country Link
US (1) US8431706B2 (he)
EP (1) EP2744806B1 (he)
JP (1) JP5903162B2 (he)
KR (1) KR101570624B1 (he)
CN (1) CN103687856B (he)
AP (1) AP3589A (he)
AR (1) AR087451A1 (he)
AU (1) AU2012295372A1 (he)
BR (1) BR112014003079A2 (he)
CA (1) CA2843474C (he)
CL (1) CL2014000357A1 (he)
CO (1) CO6880069A2 (he)
CR (1) CR20140052A (he)
DO (1) DOP2014000018A (he)
EA (1) EA022165B1 (he)
EC (1) ECSP14013211A (he)
ES (1) ES2578165T3 (he)
GT (1) GT201400022A (he)
IL (1) IL230635A (he)
IN (1) IN2014MN00191A (he)
MA (1) MA35351B1 (he)
MX (1) MX2014001832A (he)
PE (1) PE20140831A1 (he)
SG (1) SG11201401793PA (he)
TN (1) TN2014000058A1 (he)
TW (1) TWI537262B (he)
UA (1) UA110983C2 (he)
WO (1) WO2013025424A1 (he)
ZA (1) ZA201400705B (he)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2016009176A0 (en) 2013-11-14 2016-04-30 Cadila Healthcare Ltd Novel heterocyclic compounds
US9957219B2 (en) 2013-12-04 2018-05-01 Merck Sharp & Dohme Corp. Antidiabetic bicyclic compounds
WO2015119899A1 (en) 2014-02-06 2015-08-13 Merck Sharp & Dohme Corp. Antidiabetic compounds
CN109666027A (zh) * 2017-10-17 2019-04-23 中国科学院上海药物研究所 一类酰胺结构的gpr40激动剂化合物及其用途
JP7289305B2 (ja) 2018-01-08 2023-06-09 セロン ファーマ エス.アー. Gpr40アゴニストとしての3-フェニル-4-ヘキシン酸誘導体
EP4227302A1 (en) 2018-02-13 2023-08-16 Gilead Sciences, Inc. Pd-1/pd-l1 inhibitors
CN112041311B (zh) 2018-04-19 2023-10-03 吉利德科学公司 Pd-1/pd-l1抑制剂
TWI809427B (zh) 2018-07-13 2023-07-21 美商基利科學股份有限公司 Pd‐1/pd‐l1抑制劑
EP3870566A1 (en) 2018-10-24 2021-09-01 Gilead Sciences, Inc. Pd-1/pd-l1 inhibitors
TWI751585B (zh) * 2019-06-28 2022-01-01 美商美國禮來大藥廠 類升糖素肽1受體促效劑
CA3156985A1 (en) 2019-10-07 2021-04-15 Kallyope, Inc. Gpr119 agonists
EP4052790A4 (en) * 2019-10-31 2023-12-27 China Petroleum & Chemical Corporation SUPPORTED CATALYST, PRODUCTION PROCESS THEREOF AND APPLICATION THEREOF
BR112022023359A2 (pt) 2020-05-19 2023-04-18 Kallyope Inc Ativadores de ampk
AU2021297323A1 (en) 2020-06-26 2023-02-16 Kallyope, Inc. AMPK activators
KR102699076B1 (ko) * 2021-04-01 2024-08-27 현대약품 주식회사 3-(4-(벤질옥시)페닐)헥스-4-이노익산 유도체의 신규 용도
CN115317484B (zh) * 2022-08-26 2023-07-18 北京箭牧科技有限公司 Ly2922470在制备预防或治疗脑血管疾病或组织缺血再灌注损伤药物中的应用
CN115671105B (zh) * 2022-11-22 2023-10-27 北京箭牧科技有限公司 Ly2922470在制备预防或治疗肾脏疾病药物中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060004012A1 (en) * 2004-02-27 2006-01-05 Michelle Akerman Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
WO2011066183A1 (en) * 2009-11-30 2011-06-03 Eli Lilly And Company Novel spiropiperidine compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197786B1 (en) * 1998-09-17 2001-03-06 Pfizer Inc 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
GT199900147A (es) * 1998-09-17 1999-09-06 1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas.
CN1288148C (zh) * 2001-03-27 2006-12-06 埃科特莱茵药品有限公司 作为尾加压素ii受体拮抗剂的1,2,3,4-四氢异喹啉的衍生物
WO2005087710A1 (ja) * 2004-03-15 2005-09-22 Takeda Pharmaceutical Company Limited アミノフェニルプロパン酸誘導体
EP2253315A1 (en) * 2004-03-30 2010-11-24 Takeda Pharmaceutical Company Limited Alkoxyphenylpropanoic acid derivatives
AR078522A1 (es) * 2009-10-15 2011-11-16 Lilly Co Eli Compuesto de espiropiperidina, composicion farmaceutica que lo comprende, su uso para preparar un medicamento util para tratar diabetes y compuesto intermediario para su sintesis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060004012A1 (en) * 2004-02-27 2006-01-05 Michelle Akerman Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
WO2011066183A1 (en) * 2009-11-30 2011-06-03 Eli Lilly And Company Novel spiropiperidine compounds

Also Published As

Publication number Publication date
US8431706B2 (en) 2013-04-30
CO6880069A2 (es) 2014-02-28
IL230635A (he) 2015-11-30
MA35351B1 (fr) 2014-08-01
CR20140052A (es) 2014-06-20
DOP2014000018A (es) 2014-04-15
SG11201401793PA (en) 2014-09-26
AP2014007436A0 (en) 2014-02-28
TWI537262B (zh) 2016-06-11
TW201319060A (zh) 2013-05-16
UA110983C2 (uk) 2016-03-10
CA2843474C (en) 2015-12-15
NZ621248A (en) 2015-08-28
EA022165B1 (ru) 2015-11-30
BR112014003079A2 (pt) 2017-02-21
GT201400022A (es) 2015-01-16
IL230635A0 (he) 2014-03-31
KR101570624B1 (ko) 2015-11-19
EP2744806A1 (en) 2014-06-25
WO2013025424A1 (en) 2013-02-21
CN103687856A (zh) 2014-03-26
AR087451A1 (es) 2014-03-26
CL2014000357A1 (es) 2014-09-05
AU2012295372A1 (en) 2014-01-23
EP2744806B1 (en) 2016-04-27
ECSP14013211A (es) 2014-03-31
MX2014001832A (es) 2014-02-27
ZA201400705B (en) 2015-11-25
JP5903162B2 (ja) 2016-04-13
CN103687856B (zh) 2015-07-22
CA2843474A1 (en) 2013-02-21
IN2014MN00191A (he) 2015-08-21
US20130045990A1 (en) 2013-02-21
JP2014521744A (ja) 2014-08-28
ES2578165T3 (es) 2016-07-21
TN2014000058A1 (en) 2015-07-01
KR20140041835A (ko) 2014-04-04
PE20140831A1 (es) 2014-07-14
EA201490269A1 (ru) 2014-05-30

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