AP3491A - Triazolopyridines - Google Patents

Triazolopyridines

Info

Publication number
AP3491A
AP3491A AP2013007182A AP2013007182A AP3491A AP 3491 A AP3491 A AP 3491A AP 2013007182 A AP2013007182 A AP 2013007182A AP 2013007182 A AP2013007182 A AP 2013007182A AP 3491 A AP3491 A AP 3491A
Authority
AP
ARIPO
Prior art keywords
triazolopyridines
Prior art date
Application number
AP2013007182A
Other languages
English (en)
Other versions
AP2013007182A0 (en
Inventor
Hans Briem
Philip Lienau
Antje Margret Wengner
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of AP2013007182A0 publication Critical patent/AP2013007182A0/xx
Application granted granted Critical
Publication of AP3491A publication Critical patent/AP3491A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AP2013007182A 2011-04-21 2012-04-16 Triazolopyridines AP3491A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11163342 2011-04-21
EP11167872 2011-05-27
PCT/EP2012/056914 WO2012143329A1 (en) 2011-04-21 2012-04-16 Triazolopyridines

Publications (2)

Publication Number Publication Date
AP2013007182A0 AP2013007182A0 (en) 2013-10-31
AP3491A true AP3491A (en) 2015-12-31

Family

ID=46124297

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2013007182A AP3491A (en) 2011-04-21 2012-04-16 Triazolopyridines

Country Status (39)

Country Link
US (1) US20140120087A1 (zh)
EP (1) EP2699575B1 (zh)
JP (1) JP5989091B2 (zh)
KR (1) KR20140025470A (zh)
CN (1) CN103608350B (zh)
AP (1) AP3491A (zh)
AR (1) AR086191A1 (zh)
AU (1) AU2012244859B2 (zh)
CA (1) CA2833657A1 (zh)
CL (1) CL2013003044A1 (zh)
CO (1) CO6801751A2 (zh)
CR (1) CR20130539A (zh)
CY (1) CY1116439T1 (zh)
DK (1) DK2699575T3 (zh)
DO (1) DOP2013000244A (zh)
EA (1) EA023766B1 (zh)
EC (1) ECSP13013011A (zh)
ES (1) ES2539265T3 (zh)
GT (1) GT201300254A (zh)
HK (1) HK1190398A1 (zh)
HR (1) HRP20150517T1 (zh)
HU (1) HUE025496T2 (zh)
IL (1) IL228704A0 (zh)
JO (1) JO3040B1 (zh)
MA (1) MA35049B1 (zh)
ME (1) ME02143B (zh)
MX (1) MX348783B (zh)
MY (1) MY164939A (zh)
PE (1) PE20141351A1 (zh)
PL (1) PL2699575T3 (zh)
PT (1) PT2699575E (zh)
RS (1) RS54044B1 (zh)
SA (1) SA112330466B1 (zh)
SG (1) SG194003A1 (zh)
SI (1) SI2699575T1 (zh)
TW (1) TWI558703B (zh)
UY (1) UY34034A (zh)
WO (1) WO2012143329A1 (zh)
ZA (1) ZA201308707B (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3181555B1 (en) 2011-04-21 2018-11-28 Gilead Sciences, Inc. Benzothiazole compounds and their pharmaceutical use
UA112096C2 (uk) * 2011-12-12 2016-07-25 Байєр Інтеллектуал Проперті Гмбх Заміщені триазолопіридини та їх застосування як інгібіторів ttk
WO2013103724A1 (en) 2012-01-04 2013-07-11 Gilead Sciences, Inc. 2- (tert - butoxy) -2- (7 -methylquinolin- 6 - yl) acetic acid derivatives for treating aids
US9284323B2 (en) 2012-01-04 2016-03-15 Gilead Sciences, Inc. Naphthalene acetic acid derivatives against HIV infection
CA2867061A1 (en) 2012-03-14 2013-09-19 Bayer Intellectual Property Gmbh Substituted imidazopyridazines
MX2015000348A (es) 2012-07-10 2015-04-14 Bayer Pharma AG Metodos para preparar triazolopiridinas sustituidas.
WO2014020043A1 (en) 2012-08-02 2014-02-06 Bayer Pharma Aktiengesellschaft Combinations for the treatment of cancer
WO2014020041A1 (en) 2012-08-02 2014-02-06 Bayer Pharma Aktiengesellschaft Combinations for the treatment of cancer
JP2016527193A (ja) * 2013-06-07 2016-09-08 バイエル・ファルマ・アクティエンゲゼルシャフト 置換トリアゾロピリジン
JP2016520634A (ja) * 2013-06-07 2016-07-14 バイエル・ファルマ・アクティエンゲゼルシャフト 置換トリアゾロピリジン
WO2014198594A1 (en) * 2013-06-10 2014-12-18 Bayer Pharma Aktiengesellschaft Novel compounds for the treatment of cancer
TN2015000543A1 (en) * 2013-06-11 2017-04-06 Bayer Pharma AG Combinations for the treatment of cancer comprising a mps-1 kinase inhibitor and a mitotic inhibitor
US9586958B2 (en) * 2013-06-11 2017-03-07 Bayer Pharma Aktiengesellschaft Prodrug derivatives of substituted triazolopyridines
EP2860177A3 (en) 2013-09-20 2015-06-10 Bayer Intellectual Property GmbH Synthesis of functionalized arenes
CN107567503B (zh) 2015-04-17 2022-03-22 荷兰转化研究中心有限责任公司 用于ttk抑制剂化疗的预后生物标记
JP7111733B2 (ja) * 2017-03-16 2022-08-02 江蘇恒瑞医薬股▲ふん▼有限公司 ヘテロアリール[4,3-c]ピリミジン-5-アミン誘導体、その製造方法、およびその医薬の使用
US20230086702A1 (en) 2019-04-18 2023-03-23 The Johns Hopkins University Substituted 2-amino-pyrazolyl-[1,2,4]triazolo[1,5a]pyridine derivatives and use thereof
US11529350B2 (en) 2019-07-03 2022-12-20 Sumitomo Pharma Oncology, Inc. Tyrosine kinase non-receptor 1 (TNK1) inhibitors and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008025821A1 (en) * 2006-08-30 2008-03-06 Cellzome Limited Triazole derivatives as kinase inhibitors
WO2011063908A1 (en) * 2009-11-30 2011-06-03 Bayer Schering Pharma Aktiengesellschaft Triazolopyridines

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
US5011472A (en) 1988-09-06 1991-04-30 Brown University Research Foundation Implantable delivery system for biological factors
RU2007109778A (ru) 2004-08-17 2008-09-27 Галдерма Ресерч Энд Девелопмент, С.Н.С. (Fr) Новые биароматические соединения, которые активируют рецепторы типа ppar, и их применение в косметических и фармацевтических композициях
PE20090492A1 (es) 2007-07-18 2009-05-27 Novartis Ag Compuestos heterociclos como inhibidores de cinasa de fosfatidil-inositol-3
JP2010536841A (ja) 2007-08-23 2010-12-02 アストラゼネカ アクチボラグ 増殖性疾患治療のためのttk/mps1阻害剤としての2−アニリノプリン−8−オン類
MX2010002312A (es) 2007-08-31 2010-03-18 Merck Serono Sa Compuestos de triazolopiridina y su uso como inhibidores de cinasa reguladora de señal de apoptosis.
GB0719803D0 (en) * 2007-10-10 2007-11-21 Cancer Rec Tech Ltd Therapeutic compounds and their use
EA201000797A1 (ru) * 2007-11-27 2011-02-28 Целльзом Лимитид Аминотриазолы в качестве ингибиторов pi3k
SG173610A1 (en) * 2009-02-13 2011-09-29 Fovea Pharmaceuticals Sa [1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors
EP2424537B1 (en) 2009-04-29 2015-07-08 Bayer Intellectual Property GmbH Substituted imidazoquinoxalines
EP2473498A1 (en) 2009-09-04 2012-07-11 Bayer Pharma Aktiengesellschaft Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors
UY33452A (es) * 2010-06-16 2012-01-31 Bayer Schering Pharma Ag Triazolopiridinas sustituidas

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008025821A1 (en) * 2006-08-30 2008-03-06 Cellzome Limited Triazole derivatives as kinase inhibitors
WO2011063908A1 (en) * 2009-11-30 2011-06-03 Bayer Schering Pharma Aktiengesellschaft Triazolopyridines

Also Published As

Publication number Publication date
AP2013007182A0 (en) 2013-10-31
JO3040B1 (ar) 2016-09-05
HK1190398A1 (zh) 2014-07-04
CL2013003044A1 (es) 2014-05-02
AR086191A1 (es) 2013-11-27
EP2699575B1 (en) 2015-03-25
ME02143B (me) 2015-10-20
JP5989091B2 (ja) 2016-09-07
SI2699575T1 (sl) 2015-10-30
UY34034A (es) 2012-11-30
NZ616456A (en) 2015-09-25
CN103608350B (zh) 2015-11-25
CO6801751A2 (es) 2013-11-29
EA201301181A1 (ru) 2014-08-29
PT2699575E (pt) 2015-07-29
IL228704A0 (en) 2013-12-31
MY164939A (en) 2018-02-15
SG194003A1 (en) 2013-11-29
EA023766B1 (ru) 2016-07-29
TW201245194A (en) 2012-11-16
ZA201308707B (en) 2016-07-27
WO2012143329A1 (en) 2012-10-26
HUE025496T2 (en) 2016-04-28
PE20141351A1 (es) 2014-11-01
EP2699575A1 (en) 2014-02-26
DOP2013000244A (es) 2014-03-16
RS54044B1 (en) 2015-10-30
JP2014511887A (ja) 2014-05-19
MX2013012289A (es) 2013-11-21
PL2699575T3 (pl) 2015-08-31
DK2699575T3 (da) 2015-06-22
TWI558703B (zh) 2016-11-21
KR20140025470A (ko) 2014-03-04
MX348783B (es) 2017-06-28
GT201300254A (es) 2015-09-01
ECSP13013011A (es) 2013-12-31
CN103608350A (zh) 2014-02-26
CY1116439T1 (el) 2017-02-08
CA2833657A1 (en) 2012-10-26
AU2012244859A1 (en) 2013-10-31
AU2012244859B2 (en) 2017-06-08
SA112330466B1 (ar) 2015-09-28
MA35049B1 (fr) 2014-04-03
US20140120087A1 (en) 2014-05-01
CR20130539A (es) 2013-12-04
ES2539265T3 (es) 2015-06-29
HRP20150517T1 (hr) 2015-06-19

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