HK1190398A1 - 三唑並吡啶類化合物 - Google Patents

三唑並吡啶類化合物

Info

Publication number
HK1190398A1
HK1190398A1 HK14103581.3A HK14103581A HK1190398A1 HK 1190398 A1 HK1190398 A1 HK 1190398A1 HK 14103581 A HK14103581 A HK 14103581A HK 1190398 A1 HK1190398 A1 HK 1190398A1
Authority
HK
Hong Kong
Prior art keywords
triazolopyridines
Prior art date
Application number
HK14103581.3A
Other languages
English (en)
Inventor
Volker Schulze
Dirk Kosemund
Antje Margret Wengner
Gerhard Siemeister
Detlef Stckigt
Philip Lienau
Hartmut Schirok
Hans Briem
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of HK1190398A1 publication Critical patent/HK1190398A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK14103581.3A 2011-04-21 2014-04-15 三唑並吡啶類化合物 HK1190398A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11163342 2011-04-21
EP11167872 2011-05-27
PCT/EP2012/056914 WO2012143329A1 (en) 2011-04-21 2012-04-16 Triazolopyridines

Publications (1)

Publication Number Publication Date
HK1190398A1 true HK1190398A1 (zh) 2014-07-04

Family

ID=46124297

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14103581.3A HK1190398A1 (zh) 2011-04-21 2014-04-15 三唑並吡啶類化合物

Country Status (39)

Country Link
US (1) US20140120087A1 (zh)
EP (1) EP2699575B1 (zh)
JP (1) JP5989091B2 (zh)
KR (1) KR20140025470A (zh)
CN (1) CN103608350B (zh)
AP (1) AP3491A (zh)
AR (1) AR086191A1 (zh)
AU (1) AU2012244859B2 (zh)
CA (1) CA2833657A1 (zh)
CL (1) CL2013003044A1 (zh)
CO (1) CO6801751A2 (zh)
CR (1) CR20130539A (zh)
CY (1) CY1116439T1 (zh)
DK (1) DK2699575T3 (zh)
DO (1) DOP2013000244A (zh)
EA (1) EA023766B1 (zh)
EC (1) ECSP13013011A (zh)
ES (1) ES2539265T3 (zh)
GT (1) GT201300254A (zh)
HK (1) HK1190398A1 (zh)
HR (1) HRP20150517T1 (zh)
HU (1) HUE025496T2 (zh)
IL (1) IL228704A0 (zh)
JO (1) JO3040B1 (zh)
MA (1) MA35049B1 (zh)
ME (1) ME02143B (zh)
MX (1) MX348783B (zh)
MY (1) MY164939A (zh)
PE (1) PE20141351A1 (zh)
PL (1) PL2699575T3 (zh)
PT (1) PT2699575E (zh)
RS (1) RS54044B1 (zh)
SA (1) SA112330466B1 (zh)
SG (1) SG194003A1 (zh)
SI (1) SI2699575T1 (zh)
TW (1) TWI558703B (zh)
UY (1) UY34034A (zh)
WO (1) WO2012143329A1 (zh)
ZA (1) ZA201308707B (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2013012266A (es) 2011-04-21 2013-11-22 Gilead Sciences Inc Compuestos de benzotiazol y su uso farmaceutico.
UA112096C2 (uk) * 2011-12-12 2016-07-25 Байєр Інтеллектуал Проперті Гмбх Заміщені триазолопіридини та їх застосування як інгібіторів ttk
WO2013103738A1 (en) 2012-01-04 2013-07-11 Gilead Sciences, Inc. Napthalene acetic acid derivatives against hiv infection
US9376392B2 (en) 2012-01-04 2016-06-28 Gilead Sciences, Inc. 2-(tert-butoxy)-2-(7-methylquinolin-6-yl) acetic acid derivatives for treating AIDS
US9512126B2 (en) 2012-03-14 2016-12-06 Bayer Intellectual Property Gmbh Substituted imidazopyridazines
EA027544B1 (ru) 2012-07-10 2017-08-31 Байер Фарма Акциенгезельшафт Способ получения замещенных триазолопиридинов
WO2014020041A1 (en) 2012-08-02 2014-02-06 Bayer Pharma Aktiengesellschaft Combinations for the treatment of cancer
WO2014020043A1 (en) 2012-08-02 2014-02-06 Bayer Pharma Aktiengesellschaft Combinations for the treatment of cancer
WO2014195276A1 (en) * 2013-06-07 2014-12-11 Bayer Pharma Aktiengesellschaft Substituted triazolopyridines having activity as mps-1 inhibitors
WO2014195274A1 (en) * 2013-06-07 2014-12-11 Bayer Pharma Aktiengesellschaft Substituted triazolopyridines
EA201501175A1 (ru) * 2013-06-10 2016-10-31 Байер Фарма Акциенгезельшафт Новые соединения для лечения злокачественного новообразования
PL3008062T3 (pl) 2013-06-11 2017-08-31 Bayer Pharma Aktiengesellschaft Pochodne proleki podstawionych triazolopirydyn
EP3007692A1 (en) * 2013-06-11 2016-04-20 Bayer Pharma Aktiengesellschaft Combinations for the treatment of cancer comprising a mps-1 kinase inhibitor and a mitotic inhibitor
EP2860177A3 (en) 2013-09-20 2015-06-10 Bayer Intellectual Property GmbH Synthesis of functionalized arenes
CA2981844A1 (en) 2015-04-17 2016-10-20 Netherlands Translational Research Center B.V. Prognostic biomarkers for ttk inhibitor chemotherapy
EP3575301A4 (en) * 2017-03-16 2020-08-05 Jiangsu Hengrui Medicine Co., Ltd. HETEROARYL [4,3-C] PYRIMIDINE-5-AMINE DERIVATIVE, PROCESS FOR PREPARATION AND MEDICAL USES
AU2020257301A1 (en) 2019-04-18 2021-11-11 The Johns Hopkins University Substituted 2-amino-pyrazolyl-(1,2,4)triazolo(1,5a) pyridine derivatives and use thereof
JP2022539208A (ja) 2019-07-03 2022-09-07 スミトモ ファーマ オンコロジー, インコーポレイテッド チロシンキナーゼ非受容体1(tnk1)阻害剤およびその使用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
US5011472A (en) 1988-09-06 1991-04-30 Brown University Research Foundation Implantable delivery system for biological factors
MX2007001943A (es) 2004-08-17 2007-05-09 Galderma Res & Dev Nuevos compuestos biaromaticos activadores de los receptores del tipo receptor activado del proliferador de peroxisoma (ppar) y su uso en composiciones cosmeticas o farmaceuticas.
AU2007291190A1 (en) * 2006-08-30 2008-03-06 Cellzome Limited Triazole derivatives as kinase inhibitors
JP2010533680A (ja) * 2007-07-18 2010-10-28 ノバルティス アーゲー 二環ヘテロアリール化合物およびそれらのキナーゼ阻害剤としての使用
NZ584138A (en) 2007-08-23 2011-10-28 Astrazeneca Ab 2-anilinopurin-8-ones as inhibitors of ttk/mps1 for the treatment of proliferative disorders
AU2008291075A1 (en) * 2007-08-31 2009-03-05 Merck Serono S.A. Triazolopyridine compounds and their use as ask inhibitors
GB0719803D0 (en) * 2007-10-10 2007-11-21 Cancer Rec Tech Ltd Therapeutic compounds and their use
BRPI0819606A2 (pt) * 2007-11-27 2017-05-09 Cellzome Ltd amino triazóis como inobidores de pi3k
WO2010092041A1 (en) 2009-02-13 2010-08-19 Fovea Pharmaceuticals Sa [1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors
EP2424537B1 (en) 2009-04-29 2015-07-08 Bayer Intellectual Property GmbH Substituted imidazoquinoxalines
CA2772790C (en) 2009-09-04 2017-06-27 Benjamin Bader Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors
EP2343297A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridines
UY33452A (es) * 2010-06-16 2012-01-31 Bayer Schering Pharma Ag Triazolopiridinas sustituidas

Also Published As

Publication number Publication date
CN103608350A (zh) 2014-02-26
TW201245194A (en) 2012-11-16
RS54044B1 (en) 2015-10-30
EP2699575A1 (en) 2014-02-26
CR20130539A (es) 2013-12-04
TWI558703B (zh) 2016-11-21
JO3040B1 (ar) 2016-09-05
AP3491A (en) 2015-12-31
AU2012244859B2 (en) 2017-06-08
CN103608350B (zh) 2015-11-25
SA112330466B1 (ar) 2015-09-28
HRP20150517T1 (hr) 2015-06-19
KR20140025470A (ko) 2014-03-04
ZA201308707B (en) 2016-07-27
CO6801751A2 (es) 2013-11-29
AU2012244859A1 (en) 2013-10-31
GT201300254A (es) 2015-09-01
PT2699575E (pt) 2015-07-29
CA2833657A1 (en) 2012-10-26
WO2012143329A1 (en) 2012-10-26
DK2699575T3 (da) 2015-06-22
EA023766B1 (ru) 2016-07-29
SI2699575T1 (sl) 2015-10-30
ME02143B (me) 2015-10-20
UY34034A (es) 2012-11-30
PE20141351A1 (es) 2014-11-01
MA35049B1 (fr) 2014-04-03
MY164939A (en) 2018-02-15
PL2699575T3 (pl) 2015-08-31
CY1116439T1 (el) 2017-02-08
CL2013003044A1 (es) 2014-05-02
MX348783B (es) 2017-06-28
ES2539265T3 (es) 2015-06-29
AR086191A1 (es) 2013-11-27
SG194003A1 (en) 2013-11-29
US20140120087A1 (en) 2014-05-01
ECSP13013011A (es) 2013-12-31
NZ616456A (en) 2015-09-25
DOP2013000244A (es) 2014-03-16
IL228704A0 (en) 2013-12-31
EA201301181A1 (ru) 2014-08-29
HUE025496T2 (en) 2016-04-28
JP2014511887A (ja) 2014-05-19
AP2013007182A0 (en) 2013-10-31
MX2013012289A (es) 2013-11-21
EP2699575B1 (en) 2015-03-25
JP5989091B2 (ja) 2016-09-07

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20200412