AP3217A - 5-Amino-4-hydroxypentoyl amides - Google Patents

5-Amino-4-hydroxypentoyl amides

Info

Publication number
AP3217A
AP3217A AP2012006228A AP2012006228A AP3217A AP 3217 A AP3217 A AP 3217A AP 2012006228 A AP2012006228 A AP 2012006228A AP 2012006228 A AP2012006228 A AP 2012006228A AP 3217 A AP3217 A AP 3217A
Authority
AP
ARIPO
Prior art keywords
hydroxypentoyl
amides
amino
hydroxypentoyl amides
Prior art date
Application number
AP2012006228A
Other languages
English (en)
Other versions
AP2012006228A0 (en
Inventor
Bart Rudolf Romanie Kesteleyn
Wim Bert Griet Schepens
Jörg Kurt Wegner
Original Assignee
Medivir Ab
Janssen R & D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivir Ab, Janssen R & D filed Critical Medivir Ab
Publication of AP2012006228A0 publication Critical patent/AP2012006228A0/xx
Application granted granted Critical
Publication of AP3217A publication Critical patent/AP3217A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AP2012006228A 2009-12-11 2010-12-10 5-Amino-4-hydroxypentoyl amides AP3217A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09178979 2009-12-11
EP10162370 2010-05-10
PCT/EP2010/069328 WO2011070131A1 (en) 2009-12-11 2010-12-10 5-amino- 4-hydroxypentoyl amides

Publications (2)

Publication Number Publication Date
AP2012006228A0 AP2012006228A0 (en) 2012-04-30
AP3217A true AP3217A (en) 2015-04-30

Family

ID=43534084

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2012006228A AP3217A (en) 2009-12-11 2010-12-10 5-Amino-4-hydroxypentoyl amides

Country Status (24)

Country Link
US (1) US8592429B2 (ru)
EP (1) EP2509950B1 (ru)
JP (1) JP5797662B2 (ru)
KR (1) KR101771698B1 (ru)
CN (1) CN102770413B (ru)
AP (1) AP3217A (ru)
AR (1) AR079354A1 (ru)
AU (1) AU2010329867B2 (ru)
BR (1) BR112012013493B1 (ru)
CA (1) CA2783929C (ru)
DK (1) DK2509950T3 (ru)
EA (1) EA020758B1 (ru)
ES (1) ES2536774T3 (ru)
HK (1) HK1177454A1 (ru)
IL (1) IL219272A (ru)
JO (1) JO3090B1 (ru)
MX (1) MX2012006613A (ru)
NZ (1) NZ599916A (ru)
PL (1) PL2509950T3 (ru)
PT (1) PT2509950E (ru)
SG (1) SG181609A1 (ru)
TW (1) TWI485149B (ru)
UY (1) UY33098A (ru)
WO (1) WO2011070131A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7111733B2 (ja) 2017-03-16 2022-08-02 江蘇恒瑞医薬股▲ふん▼有限公司 ヘテロアリール[4,3-c]ピリミジン-5-アミン誘導体、その製造方法、およびその医薬の使用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL89900A0 (en) * 1988-04-12 1989-12-15 Merck & Co Inc Hiv protease inhibitors useful for the treatment of aids and pharmaceutical compositions containing them
EP0534511A1 (en) * 1991-08-16 1993-03-31 Merck & Co. Inc. HIV protease inhibitors useful for the treatment of aids
CN1089269A (zh) * 1993-01-04 1994-07-13 希巴-盖吉股份公司 新颖的作为治疗剂的5-氨基-4-羟基己酸衍生物
US5733882A (en) * 1994-01-17 1998-03-31 Smithkline Beecham Corporation Retroviral protease inhibitors
PT708085E (pt) * 1994-10-19 2002-11-29 Novartis Ag Eteres antivirais de isosteros de substrato de aspartato protease
HU229224B1 (en) * 2001-02-14 2013-09-30 Tibotec Pharmaceuticals Ltd Little Island 2-(substituted-amino)-benzothiazole sulfonamide compounds having broadspectrum hiv protease inhibitor activity and medicaments containing them
TWI286476B (en) * 2001-12-12 2007-09-11 Tibotec Pharm Ltd Combination of cytochrome P450 dependent protease inhibitors
US7834043B2 (en) * 2003-12-11 2010-11-16 Abbott Laboratories HIV protease inhibiting compounds
CN101115713A (zh) * 2005-02-10 2008-01-30 美迪维尔公司 人类免疫缺陷性病毒蛋白酶抑制剂
EP1851193B1 (en) * 2005-02-10 2009-04-22 Medivir AB Hiv protease inhibitors
WO2007048557A1 (en) * 2005-10-25 2007-05-03 Medivir Ab Protease inhibitors
JO2841B1 (en) * 2006-06-23 2014-09-15 تيبوتيك فارماسيوتيكالز ليمتد 2-(substituted-amino) -benzothiazole sulfonamide as protease inhibitors HIV (HIV)
NZ573887A (en) * 2006-07-21 2012-02-24 Gilead Sciences Inc Antiviral protease inhibitors

Also Published As

Publication number Publication date
EA201290487A1 (ru) 2012-11-30
AU2010329867A1 (en) 2012-05-24
KR20120107104A (ko) 2012-09-28
SG181609A1 (en) 2012-07-30
EP2509950A1 (en) 2012-10-17
JP5797662B2 (ja) 2015-10-21
EP2509950B1 (en) 2015-02-25
BR112012013493B1 (pt) 2020-12-08
PT2509950E (pt) 2015-06-08
AU2010329867B2 (en) 2016-01-28
ES2536774T3 (es) 2015-05-28
CA2783929A1 (en) 2011-06-16
UY33098A (es) 2011-06-30
HK1177454A1 (en) 2013-08-23
IL219272A (en) 2014-09-30
CN102770413B (zh) 2015-08-26
TW201130823A (en) 2011-09-16
CA2783929C (en) 2020-04-07
JO3090B1 (ar) 2017-03-15
TWI485149B (zh) 2015-05-21
JP2013513576A (ja) 2013-04-22
WO2011070131A1 (en) 2011-06-16
CN102770413A (zh) 2012-11-07
DK2509950T3 (en) 2015-05-18
BR112012013493A2 (pt) 2016-05-31
AP2012006228A0 (en) 2012-04-30
KR101771698B1 (ko) 2017-08-25
US20120295920A1 (en) 2012-11-22
AR079354A1 (es) 2012-01-18
EA020758B1 (ru) 2015-01-30
MX2012006613A (es) 2012-07-10
PL2509950T3 (pl) 2015-10-30
US8592429B2 (en) 2013-11-26
NZ599916A (en) 2013-10-25
BR112012013493A8 (pt) 2017-12-26
IL219272A0 (en) 2012-06-28

Similar Documents

Publication Publication Date Title
DK3023438T3 (en) Anti-gitr-antistoffer
DK2457337T3 (en) Specialtilpasset impuls-burst
EP2457176A4 (en) VIRTUAL-MACHINE-BASED APPLICATION-SERVICE PROVISION
EP2462514A4 (en) GREEN BOOKS
EP2515891A4 (en) 3-keto-N-propargyl-1-aminoindan
EP2519921A4 (en) CALL TRACING
DK2464943T3 (en) Systemintegration
GB0900568D0 (en) Poymerisation
GB0900319D0 (en) Hydrocharger
HK1177454A1 (en) 5-amino- 4-hydroxypentoyl amides 5--4--
EP2510125A4 (en) HYPER PRIMER
AU4240P (en) Tuckerbox xTriticosecale
AU4924P (en) Bonscablue Scaevola aemula
AU4925P (en) Bonscawi Scaevola aemula
AU4926P (en) Bonscalib Scaevola aemula
EG26256A (en) Oxygen hookah
GB0901192D0 (en) Seaid
AP2009000321S (en) Doropak
GB0901302D0 (en) Side-spin
GB0901193D0 (en) Birdcatcher2
AP00242S1 (en) Woodstove
GB0901126D0 (en) Eco-frame
GB0914142D0 (en) Tomisprint
AU329913S (en) Cupcan
AU324442S (en) Keylight