AP3129A - Extracellular matrix compositions - Google Patents

Extracellular matrix compositions

Info

Publication number
AP3129A
AP3129A AP2010005380A AP2010005380A AP3129A AP 3129 A AP3129 A AP 3129A AP 2010005380 A AP2010005380 A AP 2010005380A AP 2010005380 A AP2010005380 A AP 2010005380A AP 3129 A AP3129 A AP 3129A
Authority
AP
ARIPO
Prior art keywords
extracellular matrix
matrix compositions
compositions
extracellular
matrix
Prior art date
Application number
AP2010005380A
Other languages
English (en)
Other versions
AP2010005380A0 (en
Inventor
Kyle Nickey
Frank Ziegler
Mark Baumgartner
Original Assignee
Histogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Histogen Inc filed Critical Histogen Inc
Publication of AP2010005380A0 publication Critical patent/AP2010005380A0/en
Application granted granted Critical
Publication of AP3129A publication Critical patent/AP3129A/xx

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0625Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0627Hair cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0656Adult fibroblasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00Specific components of cell culture medium
    • C12N2500/02Atmosphere, e.g. low oxygen conditions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/165Vascular endothelial growth factor [VEGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40Regulators of development
    • C12N2501/415Wnt; Frizzeled
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/90Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
AP2010005380A 2008-01-30 2009-01-30 Extracellular matrix compositions AP3129A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2485408P 2008-01-30 2008-01-30
US3436108P 2008-03-06 2008-03-06
US5094008P 2008-05-06 2008-05-06
PCT/US2009/032697 WO2009097559A1 (en) 2008-01-30 2009-01-30 Extracellular matrix compositions

Publications (2)

Publication Number Publication Date
AP2010005380A0 AP2010005380A0 (en) 2010-08-31
AP3129A true AP3129A (en) 2015-02-28

Family

ID=40913280

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2010005380A AP3129A (en) 2008-01-30 2009-01-30 Extracellular matrix compositions

Country Status (12)

Country Link
US (1) US8257947B2 (ja)
EP (1) EP2262891B1 (ja)
JP (2) JP5647007B2 (ja)
KR (1) KR101650957B1 (ja)
CN (1) CN102066558B (ja)
AP (1) AP3129A (ja)
AU (1) AU2009209022B2 (ja)
BR (2) BRPI0906972B1 (ja)
CA (1) CA2714387C (ja)
SG (2) SG10201906494PA (ja)
WO (1) WO2009097559A1 (ja)
ZA (1) ZA201006148B (ja)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8361503B2 (en) 2007-03-02 2013-01-29 University of Pittsburgh—of the Commonwealth System of Higher Education Extracellular matrix-derived gels and related methods
US9283302B2 (en) 2011-12-16 2016-03-15 Cormatrix Cardiovascular, Inc. Extracellular matrix encasement structures and methods
US8524494B2 (en) 2008-01-30 2013-09-03 Histogen, Inc. Low oxygen tension and BFGF generates a multipotent stem cell from a fibroblast in vitro
WO2009111087A1 (en) * 2008-03-07 2009-09-11 Worcester Polytechnic Institute Novel use of basic fibroblast growth factor in the de-differentiation of animal connective tissue cells
AU2010271212B2 (en) * 2009-07-10 2015-07-16 Histogen, Inc. Conditioned medium and extracellular matrix compositions from cells cultured under hypoxic conditions
RU2418066C1 (ru) * 2010-04-26 2011-05-10 Учреждение Российской академии наук Государственный научный центр Российской Федерации-Институт медико-биологических проблем Российской академии наук (ГНЦ РФ-ИМБП РАН) Способ модификации пролиферативной активности и дифференцировочной потенции мультипотентных мезенхимальных стромальных клеток
WO2012018680A1 (en) * 2010-07-31 2012-02-09 Global Therapeutics Llc Methods and systems for generating a tissue pocket in a patient
CN104822342A (zh) * 2012-10-08 2015-08-05 矩阵心血管疾病有限公司 用于治疗生物组织的方法和系统
EP3461886A1 (en) 2013-02-12 2019-04-03 Replicel Life Sciences Inc. Methods for isolating non-bulbar dermal sheath cells and compositions
US9820933B2 (en) * 2013-04-19 2017-11-21 Korea University Research And Business Foundation Composition for stimulating hair growth or preventing hair loss which includes extract neural stem cell and method for producing same
US10533191B2 (en) 2014-01-15 2020-01-14 Serucell Corporation Therapeutic serum obtained from co-cultured cells
US10500233B2 (en) 2014-02-12 2019-12-10 Replicel Life Sciences Inc. Compositions and methods for treating bone, joints and cartilage
KR102440051B1 (ko) 2014-03-21 2022-09-06 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 세포외 기질로부터 유래한 최종 멸균된 하이드로겔의 제조 방법
KR101633585B1 (ko) * 2014-03-31 2016-06-27 아주대학교산학협력단 표면개질된 연골세포 유래 세포외 기질막을 유효성분으로 함유하는 유착방지용 조성물
WO2015152596A1 (ko) * 2014-03-31 2015-10-08 아주대학교산학협력단 표면개질된 연골세포 유래 세포외 기질막을 유효성분으로 함유하는 유착방지용 조성물
WO2015164728A1 (en) * 2014-04-24 2015-10-29 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Fractionating extracellular matrix to modulate bioactivity and the host response
JP6718202B2 (ja) * 2014-06-20 2020-07-08 共栄化学工業株式会社 皮膚外用剤
FR3029116B1 (fr) * 2014-12-01 2018-03-30 Advanced Chitosan Solutions Biotech Procede d'obtention d'un gel de cartilage pour la reparation cartilagineuse, comprenant du chitosane et des chondrocytes
FR3032632A1 (fr) * 2015-02-12 2016-08-19 Exel Ind Pistolet de projection d'un fluide, filtre pour un tel pistolet, et procede d'extraction d'un filtre hors d'un tel pistolet
CN104941008A (zh) * 2015-05-19 2015-09-30 烟台正海生物科技股份有限公司 一种引导组织再生膜的制备方法及其应用
CN105769381B (zh) * 2015-05-26 2018-04-17 南通大学 一种用于组织损伤修复的生物补片
JP6587877B2 (ja) * 2015-09-17 2019-10-09 日本メナード化粧品株式会社 表皮幹細胞を分離するためのマーカー及び三次元培養表皮の製造方法
CN106978394B (zh) * 2017-02-23 2020-06-23 北京恒峰铭成生物科技有限公司 一种抗慢性炎症的间充质干细胞的制备方法及其应用
CA3049990A1 (en) 2017-03-02 2018-09-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix (ecm) hydrogel and soluble fraction thereof for the treatment of cancer
US11718829B2 (en) 2017-07-28 2023-08-08 Breakthrough Tech Llc Methods and compositions for manufacturing extracellular matrix
JP7151203B2 (ja) * 2018-06-19 2022-10-12 東洋インキScホールディングス株式会社 細胞培養培地添加剤、細胞培養培地及び細胞凝集塊の製造方法
US20210299036A1 (en) * 2018-08-02 2021-09-30 Histogen, Inc. Conditioned medium and extracellular matrix compositions and uses thereof
SG11202011845XA (en) * 2018-08-03 2020-12-30 Laboratory Of Cell Applied Technologies Co Production method for culture supernatant preparation
CN110607279B (zh) * 2019-10-18 2023-09-19 深圳优圣康医学检验实验室 一种原代肿瘤细胞的3d培养体系及其培养方法和应用
US20210254008A1 (en) * 2020-02-14 2021-08-19 Allergan Sales, Llc Conditioned medium from cells cultured under hypoxic conditions and uses thereof
WO2023167082A1 (ja) * 2022-03-01 2023-09-07 国立大学法人横浜国立大学 増幅毛包間葉系細胞の製造方法及びその使用

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235312A (en) 1978-10-30 1980-11-25 Eaton Corporation Brake actuator assembly
IL74715A0 (en) * 1984-03-27 1985-06-30 Univ New Jersey Med Biodegradable matrix and methods for producing same
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US5160490A (en) * 1986-04-18 1992-11-03 Marrow-Tech Incorporated Three-dimensional cell and tissue culture apparatus
US5032508A (en) * 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5380746A (en) * 1989-05-05 1995-01-10 Goedecke Aktiengesellschaft Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
US5091173A (en) * 1989-06-29 1992-02-25 The University Of Dundee Hair growth composition
US5204382A (en) 1992-02-28 1993-04-20 Collagen Corporation Injectable ceramic compositions and methods for their preparation and use
US6733776B1 (en) * 1992-04-02 2004-05-11 Anticancer, Inc. Method for promoting hair growth
US6284284B1 (en) 1995-06-06 2001-09-04 Advanced Tissue Sciences, Inc. Compositions and methods for production and use of an injectable naturally secreted extracellular matrix
US5830708A (en) 1995-06-06 1998-11-03 Advanced Tissue Sciences, Inc. Methods for production of a naturally secreted extracellular matrix
US5833948A (en) 1995-06-15 1998-11-10 Bracco Research S.A. Blood-pool imaging composition comprising micelles containing a lipophilic chelating agent and a non-ionic surfactant
US5888551A (en) * 1995-12-11 1999-03-30 University Of Miami Hair growth stimulating composition
US5866165A (en) * 1997-01-15 1999-02-02 Orquest, Inc. Collagen-polysaccharide matrix for bone and cartilage repair
US6197586B1 (en) * 1997-12-12 2001-03-06 The Regents Of The University Of California Chondrocyte-like cells useful for tissue engineering and methods
US6610540B1 (en) * 1998-11-18 2003-08-26 California Institute Of Technology Low oxygen culturing of central nervous system progenitor cells
ES2402739T3 (es) * 1998-11-19 2013-05-08 Organogenesis Inc. Constructos tisulares modificados por bioingeniería y métodos para producirlos y utilizarlos
US20030007954A1 (en) 1999-04-12 2003-01-09 Gail K. Naughton Methods for using a three-dimensional stromal tissue to promote angiogenesis
US6372494B1 (en) * 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
US6280284B1 (en) 2000-03-17 2001-08-28 Carl Winefordner Toy submarine with counter rotating propellers
AU5301201A (en) * 2000-03-31 2001-10-15 Gen Hospital Corp Methods of modulating hair growth
US20020155440A1 (en) * 2000-12-19 2002-10-24 Ljubimova Julia Y. Using overexpression of laminin alpha 4 subunit as a diagnostic and prognostic indicator of malignant tumors
BR0206855A (pt) 2001-01-30 2006-01-17 Orthogene Inc Composições e suas aplicações para o tratamento de defeitos em cartilagem articular
ITPD20010032A1 (it) * 2001-02-09 2002-08-09 Fidia Advanced Biopolymers Srl Innesti ingegnerizzati per la riparazione di difetti osteocondrali
US20050032208A1 (en) * 2003-06-18 2005-02-10 Oh Steve Kah Weng Materials and methods to produce stem cells
WO2005054446A2 (en) 2003-12-02 2005-06-16 Universiteit Gent Use of polysulphated alginate in cellular matrices
EP1727893B1 (en) * 2004-03-09 2012-12-12 Jan-Eric W. Ahlfors Autogenic living scaffolds and living tissue matrices: methods and uses thereof
WO2005104766A2 (en) 2004-04-28 2005-11-10 Myocardial Therapeutics, Inc. Injection of bone marrow-derived conditioned medium for angiogenesis
US7828711B2 (en) * 2004-08-16 2010-11-09 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular growth and regeneration using ventricular assist device
US20060115460A1 (en) * 2004-08-30 2006-06-01 Naughton Gail K Compositions and methods comprising WNT proteins to promote repair of damaged tissue
WO2006026730A2 (en) 2004-08-30 2006-03-09 Iken Tissue Therapeutics, Inc. Cultured three dimensional tissues and uses thereof
US20070072294A1 (en) * 2004-09-30 2007-03-29 Doronin Sergey V Use of human stem cells and/or factors they produce to promote adult mammalian cardiac repair through cardiomyocyte cell division
JP2009514646A (ja) * 2005-11-08 2009-04-09 ジョージア テック リサーチ コーポレイション 胚幹細胞由来無細胞化生体材料

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KR20110011599A (ko) 2011-02-08
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EP2262891A4 (en) 2011-04-20
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BRPI0906972B1 (pt) 2021-09-08
AU2009209022B2 (en) 2014-06-12
US8257947B2 (en) 2012-09-04
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