SG10201500237TA - Extracellular matrix compositions - Google Patents

Extracellular matrix compositions

Info

Publication number
SG10201500237TA
SG10201500237TA SG10201500237TA SG10201500237TA SG10201500237TA SG 10201500237T A SG10201500237T A SG 10201500237TA SG 10201500237T A SG10201500237T A SG 10201500237TA SG 10201500237T A SG10201500237T A SG 10201500237TA SG 10201500237T A SG10201500237T A SG 10201500237TA
Authority
SG
Singapore
Prior art keywords
extracellular matrix
matrix compositions
compositions
extracellular
matrix
Prior art date
Application number
SG10201500237TA
Inventor
Gail K Naughton
Frank Ziegler
Mark Baumgartner
Kyle Nickey
Original Assignee
Histogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Histogen Inc filed Critical Histogen Inc
Publication of SG10201500237TA publication Critical patent/SG10201500237TA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0627—Hair cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0656—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/02—Atmosphere, e.g. low oxygen conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/165—Vascular endothelial growth factor [VEGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/415—Wnt; Frizzeled
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Rheumatology (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
SG10201500237TA 2008-01-30 2009-01-30 Extracellular matrix compositions SG10201500237TA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2485408P 2008-01-30 2008-01-30
US3436108P 2008-03-06 2008-03-06
US5094008P 2008-05-06 2008-05-06

Publications (1)

Publication Number Publication Date
SG10201500237TA true SG10201500237TA (en) 2015-04-29

Family

ID=40913280

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201906494PA SG10201906494PA (en) 2008-01-30 2009-01-30 Extracellular matrix compositions
SG10201500237TA SG10201500237TA (en) 2008-01-30 2009-01-30 Extracellular matrix compositions

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201906494PA SG10201906494PA (en) 2008-01-30 2009-01-30 Extracellular matrix compositions

Country Status (12)

Country Link
US (1) US8257947B2 (en)
EP (1) EP2262891B1 (en)
JP (2) JP5647007B2 (en)
KR (1) KR101650957B1 (en)
CN (1) CN102066558B (en)
AP (1) AP3129A (en)
AU (1) AU2009209022B2 (en)
BR (2) BRPI0906972B1 (en)
CA (1) CA2714387C (en)
SG (2) SG10201906494PA (en)
WO (1) WO2009097559A1 (en)
ZA (1) ZA201006148B (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008109407A2 (en) 2007-03-02 2008-09-12 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Extracellular matrix-derived gels and related methods
US9283302B2 (en) 2011-12-16 2016-03-15 Cormatrix Cardiovascular, Inc. Extracellular matrix encasement structures and methods
US8524494B2 (en) 2008-01-30 2013-09-03 Histogen, Inc. Low oxygen tension and BFGF generates a multipotent stem cell from a fibroblast in vitro
WO2009111087A1 (en) * 2008-03-07 2009-09-11 Worcester Polytechnic Institute Novel use of basic fibroblast growth factor in the de-differentiation of animal connective tissue cells
CA2767600C (en) * 2009-07-10 2022-05-31 Histogen, Inc. Conditioned medium and extracellular matrix compositions from cells cultured under hypoxic conditions
RU2418066C1 (en) * 2010-04-26 2011-05-10 Учреждение Российской академии наук Государственный научный центр Российской Федерации-Институт медико-биологических проблем Российской академии наук (ГНЦ РФ-ИМБП РАН) Method of modifying proliferative activity and differential potency of multipotent mesenchymal stromal cells
EP2598181B1 (en) * 2010-07-31 2021-04-21 Cook Medical Technologies LLC Collagenous tissue pocket for an implantable medical device, and manufacturing method therefor
JP2016500526A (en) * 2012-10-08 2016-01-14 コーマトリックス カーディオバスキュラー， インコーポレイテッドＣｏｒＭａｔｒｉｘ Ｃａｒｄｉｏｖａｓｃｕｌａｒ， Ｉｎｃ． Methods and systems for treating biological tissue of the invention
AU2014216300B2 (en) 2013-02-12 2020-02-27 Replicel Life Sciences Inc. Compositions and methods for treating and repairing tendons
CN105246494B (en) * 2013-04-19 2020-02-07 高丽大学校产学协力团 Composition comprising extract of neural stem cell for stimulating hair growth or preventing hair loss and method for producing the same
US10533191B2 (en) 2014-01-15 2020-01-14 Serucell Corporation Therapeutic serum obtained from co-cultured cells
TW201538730A (en) 2014-02-12 2015-10-16 Replicel Life Sciences Inc Compositions and methods for treating bone, joints and cartilage
US10213526B2 (en) 2014-03-21 2019-02-26 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix
KR101633585B1 (en) * 2014-03-31 2016-06-27 아주대학교산학협력단 Composition for preventing of adhesion comprising surface-modified chondrocyte-derived extracellular matrix membrane
WO2015152596A1 (en) * 2014-03-31 2015-10-08 아주대학교산학협력단 Composition for preventing adhesion, containing surface-modified chondrocyte-derived extracellular matrix membrane as active ingredient
US20170049932A1 (en) * 2014-04-24 2017-02-23 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Fractionating Extracellular Matrix to Modulate Bioactivity and the Host Response
JP6718202B2 (en) * 2014-06-20 2020-07-08 共栄化学工業株式会社 Topical skin
FR3029116B1 (en) * 2014-12-01 2018-03-30 Advanced Chitosan Solutions Biotech PROCESS FOR OBTAINING A CARTILAGE GEL FOR CARTILAGE REPAIR COMPRISING CHITOSAN AND CHONDROCYTES
FR3032632A1 (en) * 2015-02-12 2016-08-19 Exel Ind FLUID SPRAY GUN, FILTER FOR SUCH A GUN, AND METHOD OF EXTRACTING A FILTER OUTSIDE SUCH A GUN
CN104941008A (en) * 2015-05-19 2015-09-30 烟台正海生物科技股份有限公司 Preparation method and application of guided tissue regeneration membrane
CN105769381B (en) * 2015-05-26 2018-04-17 南通大学 A kind of biological sticking patch for tissue damage reparation
JP6587877B2 (en) * 2015-09-17 2019-10-09 日本メナード化粧品株式会社 Marker for separating epidermal stem cells and method for producing three-dimensional cultured epidermis
CN106978394B (en) * 2017-02-23 2020-06-23 北京恒峰铭成生物科技有限公司 Preparation method and application of chronic inflammation resistant mesenchymal stem cells
AU2018226871B2 (en) 2017-03-02 2023-08-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix (ECM) hydrogel and soluble fraction thereof for the treatment of cancer
US11718829B2 (en) 2017-07-28 2023-08-08 Breakthrough Tech Llc Methods and compositions for manufacturing extracellular matrix
JP7151203B2 (en) * 2018-06-19 2022-10-12 東洋インキＳｃホールディングス株式会社 Cell culture medium additive, cell culture medium, and method for producing cell aggregates
WO2020028526A1 (en) * 2018-08-02 2020-02-06 Histogen, Inc. Conditioned medium and extracellular matrix compositions and uses thereof
WO2020027336A1 (en) * 2018-08-03 2020-02-06 株式会社細胞応用技術研究所 Production method for culture supernatant preparation
CN110607279B (en) * 2019-10-18 2023-09-19 深圳优圣康医学检验实验室 3D culture system of primary tumor cells, and culture method and application thereof
US20210254008A1 (en) * 2020-02-14 2021-08-19 Allergan Sales, Llc Conditioned medium from cells cultured under hypoxic conditions and uses thereof
WO2023167082A1 (en) * 2022-03-01 2023-09-07 国立大学法人横浜国立大学 Method for producing proliferated hair follicle mesenchymal cells, and use thereof

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235312A (en) 1978-10-30 1980-11-25 Eaton Corporation Brake actuator assembly
IL74715A0 (en) 1984-03-27 1985-06-30 Univ New Jersey Med Biodegradable matrix and methods for producing same
US5266480A (en) 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US5160490A (en) 1986-04-18 1992-11-03 Marrow-Tech Incorporated Three-dimensional cell and tissue culture apparatus
US5032508A (en) 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5380746A (en) * 1989-05-05 1995-01-10 Goedecke Aktiengesellschaft Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
US5091173A (en) 1989-06-29 1992-02-25 The University Of Dundee Hair growth composition
US5204382A (en) 1992-02-28 1993-04-20 Collagen Corporation Injectable ceramic compositions and methods for their preparation and use
US6733776B1 (en) 1992-04-02 2004-05-11 Anticancer, Inc. Method for promoting hair growth
US5830708A (en) 1995-06-06 1998-11-03 Advanced Tissue Sciences, Inc. Methods for production of a naturally secreted extracellular matrix
US6284284B1 (en) 1995-06-06 2001-09-04 Advanced Tissue Sciences, Inc. Compositions and methods for production and use of an injectable naturally secreted extracellular matrix
US5833948A (en) 1995-06-15 1998-11-10 Bracco Research S.A. Blood-pool imaging composition comprising micelles containing a lipophilic chelating agent and a non-ionic surfactant
US5888551A (en) 1995-12-11 1999-03-30 University Of Miami Hair growth stimulating composition
US5866165A (en) 1997-01-15 1999-02-02 Orquest, Inc. Collagen-polysaccharide matrix for bone and cartilage repair
US6197586B1 (en) 1997-12-12 2001-03-06 The Regents Of The University Of California Chondrocyte-like cells useful for tissue engineering and methods
US6610540B1 (en) * 1998-11-18 2003-08-26 California Institute Of Technology Low oxygen culturing of central nervous system progenitor cells
BR9915476A (en) * 1998-11-19 2002-01-02 Organogenesis Inc Fabric constructs made by bioengineering and methods for their production and use
US20030007954A1 (en) 1999-04-12 2003-01-09 Gail K. Naughton Methods for using a three-dimensional stromal tissue to promote angiogenesis
US6372494B1 (en) * 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
US6280284B1 (en) 2000-03-17 2001-08-28 Carl Winefordner Toy submarine with counter rotating propellers
ATE369144T1 (en) 2000-03-31 2007-08-15 Gen Hospital Corp METHOD FOR INCREASE HAIR GROWTH USING WNT POLYPEPTIDE
US20020155440A1 (en) 2000-12-19 2002-10-24 Ljubimova Julia Y. Using overexpression of laminin alpha 4 subunit as a diagnostic and prognostic indicator of malignant tumors
WO2002060315A2 (en) 2001-01-30 2002-08-08 Orthogene, Inc. Compositions and methods for the treatment and repair of defects or lesions in articular cartilage using synovial-derived tissue or cells
ITPD20010032A1 (en) 2001-02-09 2002-08-09 Fidia Advanced Biopolymers Srl ENGINEERED GRAFTES FOR THE REPAIR OF OSTEOCONDRAL DEFECTS
US20050032208A1 (en) 2003-06-18 2005-02-10 Oh Steve Kah Weng Materials and methods to produce stem cells
DE602004010307T2 (en) 2003-12-02 2008-09-25 Universiteit Gent USE OF POLYSULPATED ALGINATE IN CELL MATRIX
AU2005300263A1 (en) * 2004-03-09 2006-05-11 Jan-Eric W. Ahlfors Autogenic living scaffolds and living tissue matrices: methods and uses thereof
WO2005104766A2 (en) 2004-04-28 2005-11-10 Myocardial Therapeutics, Inc. Injection of bone marrow-derived conditioned medium for angiogenesis
US7828711B2 (en) 2004-08-16 2010-11-09 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular growth and regeneration using ventricular assist device
AU2005279934A1 (en) 2004-08-30 2006-03-09 Theregen, Inc. Compositions and methods of promoting hair growth
WO2006026617A2 (en) 2004-08-30 2006-03-09 Iken Tissue Therapeutics, Inc. Compositions and methods of promoting hair growth
US20070072294A1 (en) 2004-09-30 2007-03-29 Doronin Sergey V Use of human stem cells and/or factors they produce to promote adult mammalian cardiac repair through cardiomyocyte cell division
US9211307B2 (en) * 2005-11-08 2015-12-15 Georgia Tech Research Corporation Acellularized biomaterial from embryonic stem cells

Also Published As

Publication number Publication date
AP2010005380A0 (en) 2010-08-31
WO2009097559A1 (en) 2009-08-06
BRPI0906972A2 (en) 2015-07-14
KR101650957B1 (en) 2016-08-24
AP3129A (en) 2015-02-28
JP5647007B2 (en) 2014-12-24
EP2262891A4 (en) 2011-04-20
JP2014221070A (en) 2014-11-27
JP2011510662A (en) 2011-04-07
ZA201006148B (en) 2011-10-26
BR122020017131B1 (en) 2023-05-16
AU2009209022A1 (en) 2009-08-06
EP2262891A1 (en) 2010-12-22
CN102066558A (en) 2011-05-18
EP2262891B1 (en) 2022-09-21
US8257947B2 (en) 2012-09-04
AU2009209022B2 (en) 2014-06-12
BRPI0906972B1 (en) 2021-09-08
CA2714387C (en) 2018-06-19
SG10201906494PA (en) 2019-09-27
US20100047305A1 (en) 2010-02-25
CN102066558B (en) 2017-02-08
KR20110011599A (en) 2011-02-08
CA2714387A1 (en) 2009-08-06

Similar Documents

Publication Publication Date Title
AP3129A (en) Extracellular matrix compositions
HUE059978T2 (en) Compositions
GB0810404D0 (en) Compositions
HK1159668A1 (en) Multi-cure compositions
GB0801119D0 (en) Composition
GB0812041D0 (en) Compositions
GB0810554D0 (en) Herbicde composition
GB0808537D0 (en) Compositions
PL2035047T3 (en) Extracellular matrix composition
GB0818804D0 (en) Compositions
GB0809808D0 (en) Composition
GB0811743D0 (en) Composition
GB0801401D0 (en) Composition
EP2357204A4 (en) Composition
GB0810359D0 (en) Composition
GB0806948D0 (en) Composition
GB0809983D0 (en) Composition
GB0804031D0 (en) Composition
GB0709099D0 (en) Extracellular matrix composition
GB0611986D0 (en) Extracellular matrix composition
SI2035047T1 (en) Extracellular matrix composition
GB0800412D0 (en) Compositions
GB0805099D0 (en) Claening compositions
GB0818050D0 (en) Compositions
GB0809354D0 (en) Compositions