AP215A - Substituted benzimidazoles, process for their preparation and their pharmaceutical use. - Google Patents

Substituted benzimidazoles, process for their preparation and their pharmaceutical use. Download PDF

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Publication number
AP215A
AP215A APAP/P/1991/000285A AP9100285A AP215A AP 215 A AP215 A AP 215A AP 9100285 A AP9100285 A AP 9100285A AP 215 A AP215 A AP 215A
Authority
AP
ARIPO
Prior art keywords
methyl
compound
compound according
benzimidazole
carbon atoms
Prior art date
Application number
APAP/P/1991/000285A
Other languages
English (en)
Other versions
AP9100285A0 (en
Inventor
Arne Elof Brandstrom
Per Lennart Lindberg
Gunnel Elisabeth Sunden
Original Assignee
Ab Astra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ab Astra filed Critical Ab Astra
Publication of AP9100285A0 publication Critical patent/AP9100285A0/xx
Application granted granted Critical
Publication of AP215A publication Critical patent/AP215A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
APAP/P/1991/000285A 1990-06-20 1991-06-19 Substituted benzimidazoles, process for their preparation and their pharmaceutical use. AP215A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9002206A SE9002206D0 (sv) 1990-06-20 1990-06-20 New compounds

Publications (2)

Publication Number Publication Date
AP9100285A0 AP9100285A0 (en) 1991-07-31
AP215A true AP215A (en) 1992-09-02

Family

ID=20379831

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1991/000285A AP215A (en) 1990-06-20 1991-06-19 Substituted benzimidazoles, process for their preparation and their pharmaceutical use.

Country Status (26)

Country Link
EP (1) EP0535081A1 (pt)
JP (1) JPH05507713A (pt)
CN (1) CN1058212A (pt)
AP (1) AP215A (pt)
AU (1) AU649453B2 (pt)
CA (1) CA2083714A1 (pt)
CZ (1) CZ279772B6 (pt)
FI (1) FI925766A0 (pt)
HU (1) HUT62881A (pt)
IE (1) IE912025A1 (pt)
IL (1) IL98470A0 (pt)
IS (1) IS3721A7 (pt)
LT (2) LT3952B (pt)
LV (1) LV10953A (pt)
MA (1) MA22199A1 (pt)
NO (1) NO924775D0 (pt)
NZ (1) NZ238546A (pt)
OA (1) OA09682A (pt)
PT (1) PT98035A (pt)
RO (1) RO110493B1 (pt)
SE (1) SE9002206D0 (pt)
TN (1) TNSN91049A1 (pt)
TW (1) TW216418B (pt)
WO (1) WO1991019711A1 (pt)
YU (1) YU104191A (pt)
ZA (2) ZA914296B (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9002043D0 (sv) * 1990-06-07 1990-06-07 Astra Ab Improved method for synthesis
SE9103776D0 (sv) * 1991-12-19 1991-12-19 Astra Ab New compounds
IS4232A (is) * 1993-12-06 1995-06-07 Astra Aktiebolag Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
SE9500478D0 (sv) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
SE9600070D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
WO2001062248A1 (en) 2000-02-24 2001-08-30 Kopran Research Laboratories Limited Orally administrable acid stable anti-ulcer benzimidazole derivatives
SE0101379D0 (sv) 2001-04-18 2001-04-18 Diabact Ab Komposition som hämmar utsöndring av magsyra
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
PT1492511E (pt) 2002-04-09 2009-04-09 Flamel Tech Sa Formulação farmacêutica oral na forma de suspensão aquosa de microcápsulas para libertação modificada de princípio(s) activo(s)
SE0203065D0 (sv) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
NZ546148A (en) 2003-09-26 2009-05-31 Alza Corp Drug coating providing high drug loading and methods for providing the same
TW200606163A (en) 2004-04-22 2006-02-16 Eisai Co Ltd Imidazopyridine compound
US8541026B2 (en) 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US20070015782A1 (en) 2005-04-15 2007-01-18 Eisai Co., Ltd. Benzimidazole compound
US9040564B2 (en) 2005-04-28 2015-05-26 Eisai R&D Management Co., Ltd. Stabilized composition
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
WO2007122686A1 (ja) * 2006-04-14 2007-11-01 Eisai R & D Management Co., Ltd. ベンズイミダゾール化合物
ES2511792T3 (es) 2006-07-25 2014-10-23 Vecta Ltd. Composiciones y métodos para la inhibición de la secreción de ácido gástrico usando derivados de pequeños ácidos dicarboxílicos en combinación con IBP
EP2065379A4 (en) * 2006-10-13 2011-01-19 Eisai R&D Man Co Ltd BENZIMIDAZOLE HAVING INHIBITORY ACTIVITY OF GASTRIC ACID SECRETION
EP2344139A1 (en) 2008-09-09 2011-07-20 AstraZeneca AB Method for delivering a pharmaceutical composition to patient in need thereof
EP2445499A4 (en) 2009-06-25 2013-02-27 Astrazeneca Ab METHOD FOR TREATING A PATIENT WITH RISK OF DEVELOPING A NSAID-ASSOCIATED SPURGE
WO2011080502A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
US20120294937A1 (en) 2009-12-29 2012-11-22 Novartis Ag New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080500A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
EP2601947A1 (en) 2011-12-05 2013-06-12 Abo Bakr Mohammed Ali Al-Mehdar Fixed-dose combination for treatment of helicobacter pylori associated diseases
BR112014016085A8 (pt) 2011-12-28 2017-07-04 Pozen Inc composições aprimoradas e métodos para distribuição de omeprazol mais ácido acetilsalicílico
IL307576A (en) * 2016-09-14 2023-12-01 Yufeng Jane Tseng Novel mutated benzimidazoles as D-amino acid oxidase (DAAO) inhibitors

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166287A1 (de) * 1984-06-16 1986-01-02 Byk Gulden Lomberg Chemische Fabrik GmbH Dialkoxypyridine, Verfahren zu ihrer Herstellung, ihre Anwendung und sie enthaltende Arzneimittel
WO1986002646A1 (en) * 1984-10-31 1986-05-09 Byk Gulden Lomberg Chemische Fabrik Gesellschaft M New picoline derivatives, preparation process thereof, utilization thereof and drugs containing them
WO1989005299A1 (en) * 1987-12-11 1989-06-15 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel benzimidazole derivatives
WO1989011479A1 (en) * 1988-05-25 1989-11-30 Byk Gulden Lomberg Chemische Fabrik Gmbh New fluoralkoxy compounds

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (pt) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
SE8300736D0 (sv) 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
SE8301182D0 (sv) 1983-03-04 1983-03-04 Haessle Ab Novel compounds
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
US4738975A (en) 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
NZ222495A (en) 1986-11-21 1991-04-26 Haessle Ab Benzimidazole derivatives and pharmaceutical compositions
DE3722810A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung
MY103790A (en) * 1987-10-30 1993-09-30 Ab Hassle Novel compound for the treatment of several bone affecting diseases

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166287A1 (de) * 1984-06-16 1986-01-02 Byk Gulden Lomberg Chemische Fabrik GmbH Dialkoxypyridine, Verfahren zu ihrer Herstellung, ihre Anwendung und sie enthaltende Arzneimittel
WO1986002646A1 (en) * 1984-10-31 1986-05-09 Byk Gulden Lomberg Chemische Fabrik Gesellschaft M New picoline derivatives, preparation process thereof, utilization thereof and drugs containing them
WO1989005299A1 (en) * 1987-12-11 1989-06-15 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel benzimidazole derivatives
WO1989011479A1 (en) * 1988-05-25 1989-11-30 Byk Gulden Lomberg Chemische Fabrik Gmbh New fluoralkoxy compounds

Also Published As

Publication number Publication date
CS189491A3 (en) 1992-04-15
WO1991019711A1 (en) 1991-12-26
LT3977B (en) 1996-06-25
NO924775L (no) 1992-12-10
IS3721A7 (is) 1991-12-21
LTIP1713A (en) 1995-08-25
HUT62881A (en) 1993-06-28
SE9002206D0 (sv) 1990-06-20
FI925766A (fi) 1992-12-18
TW216418B (pt) 1993-11-21
NO924775D0 (no) 1992-12-10
OA09682A (en) 1993-05-15
MA22199A1 (fr) 1992-04-01
CA2083714A1 (en) 1991-12-21
PT98035A (pt) 1992-03-31
AU8009791A (en) 1992-01-07
IL98470A0 (en) 1992-07-15
AU649453B2 (en) 1994-05-26
HU9204033D0 (en) 1993-03-29
LTIP1712A (en) 1995-08-25
CZ279772B6 (cs) 1995-06-14
CN1058212A (zh) 1992-01-29
JPH05507713A (ja) 1993-11-04
EP0535081A1 (en) 1993-04-07
TNSN91049A1 (fr) 1992-10-25
LT3952B (en) 1996-05-27
ZA914296B (en) 1992-03-25
AP9100285A0 (en) 1991-07-31
YU104191A (sh) 1994-01-20
FI925766A0 (fi) 1992-12-18
NZ238546A (en) 1994-03-25
RO110493B1 (ro) 1996-01-30
LV10953A (lv) 1995-12-20
IE912025A1 (en) 1992-01-01
ZA914297B (en) 1992-03-25

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