AP2006003621A0 - Methods for treatment modification and management of pains using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoin-doleline - Google Patents
Methods for treatment modification and management of pains using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoin-dolelineInfo
- Publication number
- AP2006003621A0 AP2006003621A0 AP2006003621A AP2006003621A AP2006003621A0 AP 2006003621 A0 AP2006003621 A0 AP 2006003621A0 AP 2006003621 A AP2006003621 A AP 2006003621A AP 2006003621 A AP2006003621 A AP 2006003621A AP 2006003621 A0 AP2006003621 A0 AP 2006003621A0
- Authority
- AP
- ARIPO
- Prior art keywords
- methylisoin
- doleline
- dioxopiperidin
- pains
- oxo
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/693,794 US20050203142A1 (en) | 2002-10-24 | 2003-10-23 | Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain |
PCT/US2004/012721 WO2005044178A2 (fr) | 2003-10-23 | 2004-04-23 | Procedes d'utilisation et compositions comprenant des composes immunomodulaires pour traiter, modifier et gerer la douleur |
Publications (1)
Publication Number | Publication Date |
---|---|
AP2006003621A0 true AP2006003621A0 (en) | 2006-06-30 |
Family
ID=34573202
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AP2006003621A AP2006003621A0 (en) | 2003-10-23 | 2004-04-23 | Methods for treatment modification and management of pains using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoin-doleline |
Country Status (16)
Country | Link |
---|---|
US (1) | US20050203142A1 (fr) |
EP (2) | EP1680111A4 (fr) |
JP (1) | JP2007525484A (fr) |
KR (2) | KR20060125763A (fr) |
CN (2) | CN1897945A (fr) |
AP (1) | AP2006003621A0 (fr) |
AU (2) | AU2004286819A1 (fr) |
BR (2) | BRPI0415007A (fr) |
CA (1) | CA2543160A1 (fr) |
EA (1) | EA200600820A1 (fr) |
IL (2) | IL175074A0 (fr) |
MX (2) | MXPA06004427A (fr) |
NZ (1) | NZ547129A (fr) |
OA (1) | OA13274A (fr) |
WO (2) | WO2005043971A2 (fr) |
ZA (2) | ZA200603461B (fr) |
Families Citing this family (57)
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US7629360B2 (en) * | 1999-05-07 | 2009-12-08 | Celgene Corporation | Methods for the treatment of cachexia and graft v. host disease |
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AU2002253795B2 (en) * | 2000-11-30 | 2007-02-01 | The Children's Medical Center Corporation | Synthesis of 4-Amino-Thalidomide enantiomers |
US7323479B2 (en) * | 2002-05-17 | 2008-01-29 | Celgene Corporation | Methods for treatment and management of brain cancer using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline |
US20040087558A1 (en) * | 2002-10-24 | 2004-05-06 | Zeldis Jerome B. | Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain |
UA83504C2 (en) | 2003-09-04 | 2008-07-25 | Селджин Корпорейшн | Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione |
US20050100529A1 (en) * | 2003-11-06 | 2005-05-12 | Zeldis Jerome B. | Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders |
US20050143344A1 (en) * | 2003-12-30 | 2005-06-30 | Zeldis Jerome B. | Methods and compositions using immunomodulatory compounds for the treatment and management of central nervous system disorders or diseases |
EP2505200A1 (fr) * | 2004-03-22 | 2012-10-03 | Celgene Corporation | Procédé dýutilisation et compositions comprenant des composés immunomodulateurs pour le traitement et la sclérodermie |
US20050222209A1 (en) * | 2004-04-01 | 2005-10-06 | Zeldis Jerome B | Methods and compositions for the treatment, prevention or management of dysfunctional sleep and dysfunctional sleep associated with disease |
US20050239842A1 (en) * | 2004-04-23 | 2005-10-27 | Zeldis Jerome B | Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of pulmonary hypertension |
WO2006058008A1 (fr) * | 2004-11-23 | 2006-06-01 | Celgene Corporation | Methodes et compositions comprenant l'utilisation de composes immunomodulateurs pour le traitement et la prise en charge des lesions du systeme nerveux central |
WO2006105670A1 (fr) * | 2005-04-08 | 2006-10-12 | Neuromed Pharmaceuticals Ltd. | Thérapie de combinaison qui comprend un agent bloquant les canaux calciques de type n pour le soulagement de la douleur |
EP1907373B1 (fr) * | 2005-06-30 | 2013-01-09 | Celgene Corporation | Elaboration de composes 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioniques |
CA2623648C (fr) * | 2005-09-21 | 2018-05-22 | The Regents Of The University Of California | Systemes, compositions et procedes pour representer localement et traiter la douleur |
WO2007136640A2 (fr) * | 2006-05-16 | 2007-11-29 | Celgene Corporation | Procédé de préparation de 2-(2,6-dioxopipéridin-3-yl)isoindole-1,3-dione substitué |
US8877780B2 (en) | 2006-08-30 | 2014-11-04 | Celgene Corporation | 5-substituted isoindoline compounds |
US7645767B2 (en) * | 2006-08-31 | 2010-01-12 | Trinity Laboratories, Inc. | Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy |
JP5388854B2 (ja) | 2006-09-26 | 2014-01-15 | セルジーン コーポレイション | 5−置換キナゾリノン誘導体、それを含む組成物、及びその使用方法 |
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US20090298882A1 (en) * | 2008-05-13 | 2009-12-03 | Muller George W | Thioxoisoindoline compounds and compositions comprising and methods of using the same |
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HUE037955T2 (hu) | 2011-03-11 | 2018-09-28 | Celgene Corp | A 3-(5-amino-2-metil-4-oxo-4H-kinazolin-3-il)- piperidin-2,6-dion szilárd halmazállapotú formái, valamint gyógyászati készítményei és felhasználása |
US9090585B2 (en) | 2011-03-28 | 2015-07-28 | Deuterx, Llc | 2,6-dioxo-3-deutero-piperdin-3-yl-isoindoline compounds |
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KR20140063808A (ko) | 2011-09-14 | 2014-05-27 | 셀진 코포레이션 | 시클로프로판카르복실 산{2-[(1s)-1-(3-에톡시-4-메톡시-페닐)-2-메탄술포닐-에틸]-3-옥소-2,3-디하이드로-1h-이소인돌-4-일}-아마이드의 제제 |
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ES2671608T3 (es) | 2012-02-21 | 2018-06-07 | Celgene Corporation | Formas sólidas de 3-(4-nitro-1-oxoisoindolin-2-il)piperidina-2,6-diona |
WO2013130849A1 (fr) | 2012-02-29 | 2013-09-06 | Concert Pharmaceuticals, Inc. | Dérivés de phthalimide dioxopipéridinyle substitués |
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CA2878954C (fr) | 2012-08-09 | 2020-12-08 | Benjamin M. Cohen | Sels et formes solides de la (s)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione et des compositions les comprenant et ses procedes d'utilisation |
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UA117141C2 (uk) | 2013-10-08 | 2018-06-25 | Селджин Корпорейшн | Склади (s)-3-(4-((4-(морфолінометил)бензил)оксі)-1-оксоізоіндолін-2-іл)піперидин-2,6-діону |
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-
2003
- 2003-10-23 US US10/693,794 patent/US20050203142A1/en not_active Abandoned
-
2004
- 2004-04-23 EP EP04750612A patent/EP1680111A4/fr not_active Withdrawn
- 2004-04-23 BR BRPI0415007-4A patent/BRPI0415007A/pt not_active IP Right Cessation
- 2004-04-23 CN CNA2004800381718A patent/CN1897945A/zh active Pending
- 2004-04-23 MX MXPA06004427A patent/MXPA06004427A/es unknown
- 2004-04-23 ZA ZA200603461A patent/ZA200603461B/en unknown
- 2004-04-23 KR KR1020067009895A patent/KR20060125763A/ko not_active Application Discontinuation
- 2004-04-23 WO PCT/US2004/012722 patent/WO2005043971A2/fr active Search and Examination
- 2004-04-23 MX MXPA06004381A patent/MXPA06004381A/es unknown
- 2004-04-23 CA CA002543160A patent/CA2543160A1/fr not_active Abandoned
- 2004-04-23 BR BRPI0415649-8A patent/BRPI0415649A/pt not_active IP Right Cessation
- 2004-04-23 NZ NZ547129A patent/NZ547129A/en unknown
- 2004-04-23 EP EP04750613A patent/EP1679967A4/fr not_active Withdrawn
- 2004-04-23 OA OA1200600133A patent/OA13274A/en unknown
- 2004-04-23 WO PCT/US2004/012721 patent/WO2005044178A2/fr active Search and Examination
- 2004-04-23 KR KR1020067009894A patent/KR20060123748A/ko not_active Application Discontinuation
- 2004-04-23 JP JP2006536542A patent/JP2007525484A/ja not_active Withdrawn
- 2004-04-23 AP AP2006003621A patent/AP2006003621A0/xx unknown
- 2004-04-23 EA EA200600820A patent/EA200600820A1/ru unknown
- 2004-04-23 CN CNA2004800382528A patent/CN1897816A/zh active Pending
- 2004-04-23 AU AU2004286819A patent/AU2004286819A1/en not_active Abandoned
- 2004-04-23 AU AU2004286818A patent/AU2004286818A1/en not_active Abandoned
- 2004-04-23 ZA ZA200603401A patent/ZA200603401B/en unknown
-
2006
- 2006-04-20 IL IL175074A patent/IL175074A0/en unknown
- 2006-04-23 IL IL175100A patent/IL175100A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2543160A1 (fr) | 2005-05-19 |
IL175074A0 (en) | 2008-04-13 |
CN1897945A (zh) | 2007-01-17 |
EP1680111A2 (fr) | 2006-07-19 |
CN1897816A (zh) | 2007-01-17 |
WO2005044178A3 (fr) | 2005-10-27 |
BRPI0415007A (pt) | 2006-11-07 |
MXPA06004381A (es) | 2006-07-06 |
AU2004286819A1 (en) | 2005-05-19 |
JP2007525484A (ja) | 2007-09-06 |
EP1679967A2 (fr) | 2006-07-19 |
ZA200603461B (en) | 2007-09-26 |
EP1680111A4 (fr) | 2009-07-15 |
US20050203142A1 (en) | 2005-09-15 |
NZ547129A (en) | 2008-09-26 |
IL175100A0 (en) | 2006-09-05 |
MXPA06004427A (es) | 2006-06-27 |
WO2005044178A2 (fr) | 2005-05-19 |
OA13274A (en) | 2007-01-31 |
KR20060125763A (ko) | 2006-12-06 |
EP1679967A4 (fr) | 2009-07-15 |
WO2005043971A3 (fr) | 2005-07-14 |
EA200600820A1 (ru) | 2006-08-25 |
WO2005043971A2 (fr) | 2005-05-19 |
BRPI0415649A (pt) | 2006-12-19 |
ZA200603401B (en) | 2007-09-26 |
AU2004286818A1 (en) | 2005-05-19 |
KR20060123748A (ko) | 2006-12-04 |
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