ZA200503240B - Methods of using and compositions comprising immunodulatory compounds for treatment, modification and management of pain - Google Patents

Methods of using and compositions comprising immunodulatory compounds for treatment, modification and management of pain

Info

Publication number
ZA200503240B
ZA200503240B ZA200503240A ZA200503240A ZA200503240B ZA 200503240 B ZA200503240 B ZA 200503240B ZA 200503240 A ZA200503240 A ZA 200503240A ZA 200503240 A ZA200503240 A ZA 200503240A ZA 200503240 B ZA200503240 B ZA 200503240B
Authority
ZA
South Africa
Prior art keywords
immunodulatory
pain
compositions
management
compounds
Prior art date
Application number
ZA200503240A
Inventor
Jerome B Zeldis
Faleck Herbert
Donald C Manning
Original Assignee
Gelgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gelgene Corp filed Critical Gelgene Corp
Publication of ZA200503240B publication Critical patent/ZA200503240B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
ZA200503240A 2002-10-24 2003-10-24 Methods of using and compositions comprising immunodulatory compounds for treatment, modification and management of pain ZA200503240B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42100302P 2002-10-24 2002-10-24

Publications (1)

Publication Number Publication Date
ZA200503240B true ZA200503240B (en) 2007-11-28

Family

ID=32176661

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200503240A ZA200503240B (en) 2002-10-24 2003-10-24 Methods of using and compositions comprising immunodulatory compounds for treatment, modification and management of pain

Country Status (13)

Country Link
EP (1) EP1556044A2 (en)
JP (1) JP2006507284A (en)
KR (1) KR20050057672A (en)
CN (2) CN1326522C (en)
AU (1) AU2003286663B2 (en)
BR (1) BR0315609A (en)
CA (1) CA2503536A1 (en)
HK (1) HK1088225A1 (en)
MX (1) MXPA05004182A (en)
NZ (1) NZ540028A (en)
TW (1) TW200503683A (en)
WO (1) WO2004037199A2 (en)
ZA (1) ZA200503240B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU228769B1 (en) 1996-07-24 2013-05-28 Celgene Corp Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha
US20050203142A1 (en) * 2002-10-24 2005-09-15 Zeldis Jerome B. Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain
US7563810B2 (en) 2002-11-06 2009-07-21 Celgene Corporation Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases
US20050143344A1 (en) * 2003-12-30 2005-06-30 Zeldis Jerome B. Methods and compositions using immunomodulatory compounds for the treatment and management of central nervous system disorders or diseases
US20050222209A1 (en) * 2004-04-01 2005-10-06 Zeldis Jerome B Methods and compositions for the treatment, prevention or management of dysfunctional sleep and dysfunctional sleep associated with disease
WO2006105670A1 (en) * 2005-04-08 2006-10-12 Neuromed Pharmaceuticals Ltd. Combination therapy comprising an n-type calcium channel blocker for the alleviation of pain
US20070066512A1 (en) * 2005-09-12 2007-03-22 Dominique Verhelle Methods and compositions using immunomodulatory compounds for the treatment of disorders associated with low plasma leptin levels
JP4382735B2 (en) * 2005-10-06 2009-12-16 独立行政法人科学技術振興機構 Neuropathic pain treatment
AU2007267928A1 (en) * 2006-05-26 2007-12-06 Celgene Corporation Methods and compositions using immunomodulatory compounds in combination therapy
US20110184025A1 (en) * 2006-10-19 2011-07-28 Hensel Jennifer L Methods and Compositions Using Immunomodulatory Compounds for the Treatment and Management of Spirochete and Other Obligate Intracellular Bacterial Diseases
CN101696205B (en) 2009-11-02 2011-10-19 南京卡文迪许生物工程技术有限公司 3-(substituted xylylenimine-2-yl)-2,6-dioxopiperidine polymorph and pharmaceutical composition

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215114A (en) * 1976-11-12 1980-07-29 The Upjohn Company Analgesic N-[2-(furyl-methylamino and 2-thienylmethylamino)cycloaliphatic]be
US6281230B1 (en) * 1996-07-24 2001-08-28 Celgene Corporation Isoindolines, method of use, and pharmaceutical compositions
EP2070920B8 (en) * 1996-07-24 2011-04-27 Celgene Corporation Substituted 2-(2,6-dioxopiperidin-3-yl)-phthalimides and 1-oxoisoindolines and method of reducing TNF alpha levels
HU228769B1 (en) * 1996-07-24 2013-05-28 Celgene Corp Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha
US5955476A (en) * 1997-11-18 1999-09-21 Celgene Corporation Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing inflammatory cytokine levels
US20030045552A1 (en) * 2000-12-27 2003-03-06 Robarge Michael J. Isoindole-imide compounds, compositions, and uses thereof
SE0101256D0 (en) * 2001-04-06 2001-04-06 A & Science Invest Ab Treatment of low back pain

Also Published As

Publication number Publication date
TW200503683A (en) 2005-02-01
MXPA05004182A (en) 2005-06-08
BR0315609A (en) 2005-08-23
NZ540028A (en) 2009-07-31
AU2003286663B2 (en) 2009-08-13
CN1732000A (en) 2006-02-08
KR20050057672A (en) 2005-06-16
WO2004037199A2 (en) 2004-05-06
CA2503536A1 (en) 2004-05-06
AU2003286663A1 (en) 2004-05-13
CN101108185A (en) 2008-01-23
CN1326522C (en) 2007-07-18
HK1088225A1 (en) 2006-11-03
EP1556044A2 (en) 2005-07-27
WO2004037199A3 (en) 2004-12-23
JP2006507284A (en) 2006-03-02

Similar Documents

Publication Publication Date Title
EP1680111A4 (en) Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain
EP1567157A4 (en) Methods of using and compositions comprising immunomudulatory compounds for the treatment and management of myeloproliferative diseases
EP1567158A4 (en) Methods and compositions using immunomodulatory compounds for treatment and management of cancers and other diseases
HRP20040665B1 (en) Fluoro substituted cycloalkanoindoles, compositions containing such compounds and methods of treatment
AU2003257937A8 (en) Methods and compositions for treatment of dermal conditions
IL209352A0 (en) 4-tetrazolyl-4phenylpiperidine derivatives for treating pain
EP1613266A4 (en) Methods of treating pain and compositions for use therefor
AU2003287443A8 (en) Compositions and methods for pain reduction
ZA200503240B (en) Methods of using and compositions comprising immunodulatory compounds for treatment, modification and management of pain
AU2003211009A8 (en) Compositions and methods for treating pain using cyclooxygenase-1 inhibitors
EP1551388A4 (en) Compounds useful for the treatment of cancer, compositions thereof and methods therewith
GB0211295D0 (en) Treatment of pain
EP1680132A4 (en) Methods of using and compositions comprising thalidomide for treatment, modification and management of fibromyalgia
IL166062A0 (en) Compositions and methods for therapeutic treatment
AU2003275433A8 (en) Compositions and methods for treating pain
AU2003266960A1 (en) Composition for the treatment of pain, especially for the treatment of articular pain
GB0208897D0 (en) New method of treatment
GB0217493D0 (en) Novel methods of treatment
GB0221712D0 (en) Methods of treatment
AU2003202255A8 (en) Compositions for treatment of central nervous system neoplasms, and methods of making and using the same
AU2003272327A8 (en) Methods of bone healing
GB0213198D0 (en) Method of treatment
GB0207091D0 (en) Method of treatment
IL151799A0 (en) Composition for treatment of onychomycosis
AU2003229335A8 (en) Compositions and methods for treatment of wounds